Cerebrospinal fluid hypocretin-1 (orexin A) levels in mania compared to unipolar depression and healthy controls

Neuroscience Letters

Volumn 483, Issue 1, 2010, Pages 20-22

  Schmidt, Frank M ^a   Brügel, Matthias ^a   Kratzsch, Jürgen ^a   Strauß, Maria ^a   Sander, Christian ^a   Baum, Petra ^a   Thiery, Joachim ^a   Hegerl, Ulrich ^a   Schönknecht, Peter ^a  

^a UNIVERSITY HOSPITAL LEIPZIG   (Germany)

Author keywords

Depression; Hypocretin; Locomotor activity; Mania; Narcolepsy; Vigilance

Indexed keywords

ARIPIPRAZOLE; CITALOPRAM; LITHIUM; LORAZEPAM; MIRTAZAPINE; OLANZAPINE; OREXIN A; PROMETHAZINE; PROTHAZIN; QUETIAPINE; REBOXETINE; SERTRALINE; UNCLASSIFIED DRUG; VALPROIC ACID; VENLAFAXINE;

ALERTNESS; ARTICLE; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ELECTROCORTICOGRAPHY; FEMALE; FLUOROIMMUNOASSAY; HOSPITAL ADMISSION; HUMAN; MAJOR DEPRESSION; MALE; MANIA; PRIORITY JOURNAL;

BIPOLAR DISORDER; DEPRESSIVE DISORDER, MAJOR; FEMALE; FLUORESCENCE POLARIZATION IMMUNOASSAY; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; NEUROPEPTIDES; SEVERITY OF ILLNESS INDEX;

EID: 77956171449     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.07.038     Document Type: Article

References (27)

1. Aston-Jones G., Smith R.J., Moorman D.E., Richardson K.A. Role of lateral hypothalamic orexin neurons in reward processing and addiction. Neuropharmacology 2009, 56(Suppl. 1):112-121.
2. Brundin L., Petersen A., Träskman- Bendz L. Reduced orexin levels in the cerebrospinal fluid of suicidal patients with major depressive disorder. Eur. Neuropsychiat. 2007, 17:573-579.
3. Brundin L., Björkqvist M., Träskman-Bendz L., Petersén A. Increased orexin levels in the cerebrospinal fluid the first year after a suicide attempt. J. Affect. Disord. 2009, 113:179-182.
4. Cope M.B., Li X., Jumbo- Lucioni P., DiConstanzo C.A., Jamison W.G., Kesterson R.A., Allison D.B., Nagy T.R. Risperidone alters food intake, core body temperature, and locomotor activity in mice. Physiol. Behav. 2009, 96(3):457-463.
5. Fujiki N., Yoshida Y., Ripley B., Honda K., Mignot E., Nishino S. Changes in CSF hypocretin-I (orexin A) levels in rats across 24hours and in response to food deprivation. NeuroReport 2001, 5:993-997.
6. Hamilton M. A rating scale for depression. J. Neurol. Neurosurg. Psychiat. 1960, 23:56-62.
7. Harris G.C., Wimmer M., Aston-Jones G. A role for lateral hypothalamic orexin neurons in reward seeking. Nature 2005, 437:556-559.
8. Hegerl U., Sander C., Olbrich S., Schoenknecht P. Are psychostimulants a treatment option in mania?. Pharmacopsychiatry 2009, 42(5):169-174.
9. Hudson J.I., Lipinski J.F., Keck P.E., Aizley H.G., Lukas S.E., Rothschild A.J., Waternaux C.M., Kupfer D.J. Polysomnographic characteristics of young manic patients. Arch. Gen. Psychiat. 1992, 49:378-383.
10. Lambe E.K., Olausson P., Horst N.K., Taylor J.R., Aghajanian G.K. Hypocretin and nicotine excite the same thalamocortical synapses in prefrontal cortex: correlation with improved attention in rat. J. Neurosci. 2005, 25(21):5225-5229.
11. Martins P.J., D'Almeida V., Pedrazzoli M., Lin L., Mignot E., Tufik S. Increased hypocretin-1 (orexin-a) levels in cerebrospinal fluid of rats after short-term forced activity. Regul. Pept. 2004, 117(3):155-158.
12. Mignot E., Lammers G.J., Ripley B., Okun M., Nevsimalova S., Overeem S., Vankova J., Black J., Harsh J., Bassetti C., Schrader H., Nishino S. The role of CSF- Hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias. Arch. Neurol. 2002, 59:1553-1562.
13. Mileykovskiy B.Y., Kiyashchenko L.I., Siegel J.M. Behavioral correlates of activity in identified hypocretin/orexin neurons. Neuron 2005, 46:787-798.
14. Morin L.P., Allen C.N. The circadian visual system. Brain Res. Rev. 2006, 51:1-60.
15. Nishino S. The hypothalamic peptidergic system, hypocretin/orexin and vigilance control. Neuropeptides 2007, 41:117-133.
16. Nishino S., Ripley B., Overeem S., Nevsimalova S., Lammers G.J., Vankova J., Okun M., Rogers W., Brooks S., Mignot E. Low cerebrospinal fluid hypocretin (orexin) and altered energy homeostasis in human narcolepsy. Ann. Neurol. 2001, 50:381-388.
17. Nixon J.P., Smale L. Individual differences in wheel-running rhythms are related to temporal and spatial patterns of activation of orexin A and B cells in a diurnal rodent (arvicanthis niloticus). Neuroscience 2004, 127:25-34.
18. Oken B.S., Salinsky M.C., Elsas S.M. Vigilance, alertness, or sustained attention: physiological basis and measurement. Clin. Neurophysiol. 2006, 117:1885-1901.
19. Peyron C., Faraco J., Rogers W., Ripley B., Overeem S., Charnay Y., Nevsimalova S., Aldrich M., Reynolds D., Albin R., Li R., Hungs M., Pedrazzoli M., Padigaru M., Kucherlapati M., Fan J., Maki R., Lammers G.J., Bouras C., Kucherlapati R., Nishino S., Mignot E. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nat. Med. 2000, 6:991-997.
20. Reppert S.M., Weaver D.R. Coordination of circadian timing in mammals. Nature 2002, 418:935-941.
21. Riemann D., Voderholzer U., Berger M. Sleep and sleep-wake manipulations in bipolar depression. Neuropsychobiology 2002, 45:7-12.
22. Salomon R., Ripley B., Kennedy J., Johnson B., Schmidt D., Zeitzer J.M., Nishino S., Mignot E. Diurnal variation of CSF hypocretin- 1 (Orexin-A) levels in control and depressed subjects. Soc. Biol. Psychiat. 2003, 54:96-104.
23. Small J.G., Milstein V., Malloy F.W., Medlock C.E., Klapper M.H. Clinical and quantitative EEG studies of mania. J. Affect. Disord. 1999, 53:217-224.
24. Van Sweden B. Disturbed vigilance in mania. Biol. Psychiat. 1986, 21:311-313.
25. Wehr T.A., Sack D.A., Rosenthal N.E. Sleep reduction as a final common pathway in the genesis of mania. Am. J. Psychiat. 1987, 144:201-204.
26. Wu J.C., Gillian J.C., Buchsbaum M.S., Hershey T., Johnson J.C., Bunney W.E. Effect of sleep deprivation on brain metabolism of depressed patients. Am. J. Psychiat. 1990, 149:538-543.
27. Young R.C., Biggs J.T., Ziegler E., Meyer D.A. A rating scale for mania: reliability, validity and sensitivity. Br. J. Psychiat. 1978, 133:429-435.