Down syndrome risk calculation for a twin fetus taking account of the nuchal translucency in the co-twin

Prenatal Diagnosis

Volumn 30, Issue 9, 2010, Pages 827-833

  Cuckle, Howard ^a   Maymon, Ron ^b  

^a NewYork Presbyterian Hospital   (United States)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

Correlation; Down syndrome; Nuchal translucency; Risk; Zygocity

Indexed keywords

ADULT; ARTICLE; DIZYGOTIC TWINS; DOWN SYNDROME; ETHNICITY; FEMALE; FETUS; HUMAN; MALE; MONOZYGOTIC TWINS; NUCHAL TRANSLUCENCY MEASUREMENT; PRIORITY JOURNAL; TWINS;

DISEASES IN TWINS; DOWN SYNDROME; FEMALE; HUMANS; LIKELIHOOD FUNCTIONS; MALE; MATERNAL AGE; NUCHAL TRANSLUCENCY MEASUREMENT; PREGNANCY; RISK;

EID: 77956154570     PISSN: 01973851     EISSN: 10970223     Source Type: Journal    
DOI: 10.1002/pd.2557     Document Type: Article

References (38)

1. Bortolus R, Parazzini F, Chatenoud L, Benzi G, Bianchi MM, Marini A. 1999. The epidemiology of multiple births. Hum Reprod Update 5(2): 179-187.
2. Bulmer MG. 1970. The Biology of Twinning in Man. Clarendon Press: Oxford.
3. Casasbuenas A, Wong AE, Sepulveda W. 2008. Nuchal translucency thickness in monochorionic multiple pregnancies: value in predicting pregnancy outcome. J Ultrasound Med 27(3): 363-369.
4. Cheng PJ, Huang SY, Shaw SW, et al. 2010. Difference in nuchal translucency between monozygotic and dizygotic spontaneously conceived twins. Prenat Diagn 30(3): 247-250.
5. Cuckle H, Benn P. 2010. Multianalyte maternal serum screening for chromosomal defects. In Genetic Disorders and the Fetus: Diagnosis, Prevention and Treatment (6th edn), Milunsky A, Milunsky JM (eds). Johns Hopkins University Press: Baltimore; 771-818.
6. Cuckle HS, Wald NJ, Thompson SG. 1987. Estimating a woman's risk of having a pregnancy associated with Down's syndrome using her age and serum alpha-fetoprotein level. Br J Obstet Gynaecol 94: 387-402.
7. Doyle PE, Beral V, Botting B, Wale CJ. 1990. Congenital malformations in twins in England and Wales. J Epidemiol Community Health 45: 43-48.
8. Elwood JM. 1978. Maternal and environmental factors affecting twin births in Canadian cities. Br J Obstet Gynaecol 85(5): 351-358.
9. Garchet-Beaudron A, Dreux S, Leporrier N, Oury JF, Muller F; ABA Study Group; Clinical Study Group. 2008. Second-trimester Down syndrome maternal serum marker screening: a prospective study of 11 040 twin pregnancies. Prenat Diagn 28(12): 1105-1109.
10. General Register Office. 1962. The Registrar General's Statistical Review of England and Wales for the year 1960. Part 2: Tables, Population, Her Majesty's Stationery Office: London; xi + 180.
11. Gerris J, De Neubourg D, Mangelschots K, Van Royen E, Van de Meerssche M, Valkenburg M. 1999. Prevention of twin pregnancy after in-vitro fertilization or intracytoplasmic sperm injection based on strict embryo criteria: a prospective randomized clinical trial. Hum Reprod 14(10): 2581-2587.
12. Gonće A, Borrell A, Fortuny A, et al. 2005. First-trimester screening for trisomy 21 in twin pregnancy, does the addition of biochemistry make an improvement? Prenat Diagn 25: 1156-1161. (Pubitemid 43016299)
13. Hey S, Wehrung DA. 1970. Congenital malformations in twins. Am J Hum Genet 22: 662-678.
14. Hui PW, Tang MH, Ng EH, Yeung WS, Ho PC. 2006. Nuchal translucency in dichorionic twins conceived after assisted reproduction. Prenat Diagn 26(6): 510-513.
15. Linskens IH, Spreeuwenberg MD, Blankenstein MA, van Vugt JM. 2009. Early first-trimester free beta-hCG and PAPP-A serum distributions in monochorionic and dichorionic twins. Prenat Diagn 29(1): 74-78.
16. Logghe H, Cuckle H, Sehmi I. 2003. Centre-specific ultrasound nuchal translucency medians needed for Down's syndrome screening. Prenat Diagn 23: 389-392.
17. Loos R, Derom K, Vlietinck R, Derom R. 1998. East Flanders Prospective Twin Survey (Belgium): a population-based register. Twin Res 1: 167-175. (Pubitemid 128560439)
18. Machin G, Bamforth F, Innes M, McNichol K. 1995. Some perinatal characteristics of monozygotic twins who are dichorionic. Am J Med Genet 55(1): 71-76.
19. Maymon R, Jauniaux E, Holmes A, Weiner YM, Dreazen E, Herman A. 2001. Nuchal translucency measurement and pregnancy outcome after assisted conception versus spontaneously conceived twins. Hum Reprod 16(9): 1999-2004.
20. Meyers C, Adam R, Dungan J, Prenger V. 1997. Aneuploidy in twin gestations, when is maternal age advanced? Obstet Gynecol 89: 248-251.
21. Monni G, Zoppi MA, Ibba RM, Putzolu M, Floris M. 2000. Nuchal translucency in multiple pregnancies. Croat Med J 41(3): 266-269.
22. Mutton D, Alberman E, Hook EB. 1996. Cytogenetic and epidemiological findings in Down syndrome, England and Wales 1989 to 1993. National Down Syndrome Cytogenetic Register and the Association of Clinical Cytogeneticists. J Med Genet 33(5): 387-394.
23. National Center for Health Statistics. 1992. Vital and Health Statistics. Health and demographic characteristics of twin births: United States 1988. DHHS: Hyattsville, MD; DHHS Publication No. (PHS) 92-1928.
24. Orlandi F, Rossi C, Allegra A, et al. 2002. First trimester screening with free beta-hCG, PAPP-A and nuchal translucency in pregnancies conceived with assisted reproduction. Prenat Diagn 22(8): 718-721.
25. Pandya PP, Hilbert F, Snijders RJM, Nicolaides KH. 1995. Nuchal translucency thickness and crown-rump length in twin pregnancies with chromosomally abnormal fetuses. J Utrasound Med 14: 565-568.
26. Russell RB, Petrini JR, Damus K, Mattison DR, Schwarz RH. 2003. The changing epidemiology of multiple births in the United States. Obstet Gynecol 101(1): 129-135. (Pubitemid 36057098)
27. Sebire NJ, D'Ercole C, Hughes K, Carvalho M, Nicolaides KH. 1997. Increased nuchal translucency thickness at 10-14 weeks of gestation as a predictor of severe twin-to-twin transfusion syndrome. Ultrasound Obstet Gynecol 10(2): 86-89.
28. Sebire NJ, Snijders RJM, Hughes K, Sepulveda W, Nicolaides KH. 1996. Screening for trisomy 21 in twin pregnancies by maternal age and fetal nuchal translucency thickness at 10-14 weeks of gestation. Br J Obstet Gynaecol 103: 999-1003.
29. Spencer K, Bindra R, Nix AB, Heath V, Nicolaides KH. 2003. Delta- NT or NT MoM, which is the most appropriate method for calculating accurate patient-specific risks for trisomy 21 in the first trimester? Ultrasound Obstet Gynecol 22: 142-148. (Pubitemid 36976380)
30. Spencer K, Nicolaides KH. 2003. Screening for trisomy 21 in twins using first trimester ultrasound and maternal serum biochemistry in a one-stop clinic: a review of three years experience. Br J Obstet Gyneacol. 110(3): 276-280. (Pubitemid 36298911)
31. Sperling L, Kiil C, Larsen LU, et al. 2007. Detection of chromosomal abnormalities, congenital abnormalities and transfusion syndrome in twins. Ultrasound Obstet Gynecol 29(5): 517-526.
32. Stenhouse E, Hardwick C, Maharaj S, Webb J, Kelly T, Mackenzie FM. 2002. Chorionicity determination in twin pregnancies, how accurate are we? Ultrasound Obstet Gynecol 19(4): 350-352.
33. Sundström P, Saldeen P. 2009. Cumulative delivery rate in an in vitro fertilization program with a single embryo transfer policy. Acta Obstet Gynecol Scand 88(6): 700-706.
34. Vitthala S, Gelbaya TA, Brison DR, Fitzgerald CT, Nardo LG. 2009. The risk of monozygotic twins after assisted reproductive technology: a systematic review and meta-analysis. Hum Reprod Update 15(1): 45-55.
35. Windham GC, Bjerkedal T. 1984. Malformations in twins and their siblings, Norway, 1967-79. Acta Genet Med Gemellol (Roma) 33(1): 87-95. (Pubitemid 15173366)
36. Wøjdemann KR, Larsen SO, Shalmi AC, Sundberg K, Tabor A, Christiansen M. 2006. Nuchal translucency measurements are highly correlated in both mono- and dichorionic twin pairs. Prenat Diagn 26(3): 218-220.
37. Wright D, Kagan KO, Molina FS, Gazzoni A, Nicolaides KH. 2008. A mixture model of nuchal translucency thickness in screening for chromosomal defects. Ultrasound Obstet Gynecol 31(4): 376-383.
38. Wright V, Schieve LA, Vahratian A, Reynolds MA. 2004. Monozygotic twinning associated with day 5 embryo transfer in pregnancies conceived after IVF. Hum Reprod 19(8): 1831-1836.