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Volumn 25, Issue 8, 2010, Pages 539-546

The scientific assessment of combined effects of risk factors: Different approaches in experimental biosciences and epidemiology

Author keywords

Additivity; Antagonism; Combined effect analysis; Independent action; Synergism

Indexed keywords

ARTICLE; EPIDEMIOLOGICAL DATA; HAZARD ASSESSMENT; NOMENCLATURE; PREDICTION; PUBLIC HEALTH; REGRESSION ANALYSIS; RISK FACTOR; RISK MANAGEMENT; STATISTICAL MODEL;

EID: 77956151473     PISSN: 03932990     EISSN: 15737284     Source Type: Journal    
DOI: 10.1007/s10654-010-9464-2     Document Type: Article
Times cited : (18)

References (56)
  • 3
    • 33748794547 scopus 로고    scopus 로고
    • Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
    • 10.1124/pr.58.3.10 1:CAS:528:DC%2BD28XhtVOhtLfL 16968952
    • TC Chou 2006 Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies Pharmacol Rev 58 621 681 10.1124/pr.58.3.10 1:CAS:528:DC%2BD28XhtVOhtLfL 16968952
    • (2006) Pharmacol Rev , vol.58 , pp. 621-681
    • Chou, T.C.1
  • 4
    • 0022398019 scopus 로고
    • The expected effect of a combination of agents: The general solution
    • 10.1016/S0022-5193(85)80176-4 1:CAS:528:DyaL2MXlslWntbo%3D 4021503
    • MC Berenbaum 1985 The expected effect of a combination of agents: the general solution J Theor Biol 114 413 431 10.1016/S0022-5193(85)80176-4 1:CAS:528:DyaL2MXlslWntbo%3D 4021503
    • (1985) J Theor Biol , vol.114 , pp. 413-431
    • Berenbaum, M.C.1
  • 6
    • 0028472624 scopus 로고
    • Algal toxicity of binary combinations of pesticide
    • 10.1007/BF00205150 1:CAS:528:DyaK2cXktVaqtrs%3D 8069063
    • M Faust R Altenburger W Boedeker LH Grimme 1994 Algal toxicity of binary combinations of pesticide Bull Environ Contam Toxicol 53 134 141 10.1007/BF00205150 1:CAS:528:DyaK2cXktVaqtrs%3D 8069063
    • (1994) Bull Environ Contam Toxicol , vol.53 , pp. 134-141
    • Faust, M.1    Altenburger, R.2    Boedeker, W.3    Grimme, L.H.4
  • 7
    • 0037450915 scopus 로고    scopus 로고
    • Joint algal toxicity of 16 dissimilarly acting chemicals is predictable by the concept of independent action
    • 10.1016/S0166-445X(02)00133-9 1:CAS:528:DC%2BD3sXhs1Cgu7s%3D 12615420
    • M Faust R Altenburger T Backhaus H Blanck W Boedeker P Gramatica V Hamer M Scholze M Vighi LH Grimme 2003 Joint algal toxicity of 16 dissimilarly acting chemicals is predictable by the concept of independent action Aquat Toxicol 63 1 43 63 10.1016/S0166-445X(02)00133-9 1:CAS:528:DC%2BD3sXhs1Cgu7s%3D 12615420
    • (2003) Aquat Toxicol , vol.63 , Issue.1 , pp. 43-63
    • Faust, M.1    Altenburger, R.2    Backhaus, T.3    Blanck, H.4    Boedeker, W.5    Gramatica, P.6    Hamer, V.7    Scholze, M.8    Vighi, M.9    Grimme, L.H.10
  • 8
    • 0037090577 scopus 로고    scopus 로고
    • Something from "nothing"-eight weak estrogenic chemicals combined at concentrations below NOECs produce significant mixture effects
    • 10.1021/es0101227 1:CAS:528:DC%2BD38Xhsl2nsbc%3D 11993873
    • E Silva N Rajapakse A Kortenkamp 2002 Something from "nothing"- eight weak estrogenic chemicals combined at concentrations below NOECs produce significant mixture effects Environ Sci Technol 36 8 1751 1756 10.1021/es0101227 1:CAS:528:DC%2BD38Xhsl2nsbc%3D 11993873
    • (2002) Environ Sci Technol , vol.36 , Issue.8 , pp. 1751-1756
    • Silva, E.1    Rajapakse, N.2    Kortenkamp, A.3
  • 9
    • 1642579672 scopus 로고    scopus 로고
    • Joint algal toxicity of phenylurea herbicides is equally predictable by concentration addition and independent action
    • 10.1897/02-497 1:CAS:528:DC%2BD2cXotFygsw%3D%3D 14982370
    • T Backhaus M Faust M Scholze P Gramatica M Vighi LH Grimme 2004 Joint algal toxicity of phenylurea herbicides is equally predictable by concentration addition and independent action Environ Toxicol Chem 23 2 258 264 10.1897/02-497 1:CAS:528:DC%2BD2cXotFygsw%3D%3D 14982370
    • (2004) Environ Toxicol Chem , vol.23 , Issue.2 , pp. 258-264
    • Backhaus, T.1    Faust, M.2    Scholze, M.3    Gramatica, P.4    Vighi, M.5    Grimme, L.H.6
  • 10
    • 0030292217 scopus 로고    scopus 로고
    • Regulations for combined effects of pollutants: Consequences from risk assessment in aquatic toxicology
    • 10.1016/S0278-6915(97)00088-4 1:CAS:528:DyaK2sXit1Ohu7g%3D 9119330
    • R Altenburger W Boedeker M Faust LH Grimme 1996 Regulations for combined effects of pollutants: consequences from risk assessment in aquatic toxicology Food Chem Toxicol 34 1155 1157 10.1016/S0278-6915(97)00088-4 1:CAS:528:DyaK2sXit1Ohu7g%3D 9119330
    • (1996) Food Chem Toxicol , vol.34 , pp. 1155-1157
    • Altenburger, R.1    Boedeker, W.2    Faust, M.3    Grimme, L.H.4
  • 11
    • 66149153518 scopus 로고    scopus 로고
    • Extrapolation concepts for dealing with multiple contamination in environmental risk assessment
    • 10.1897/IEAM-2008-038.1 1:CAS:528:DC%2BD1MXit1Gkurs%3D
    • R Altenburger WR Greco 2009 Extrapolation concepts for dealing with multiple contamination in environmental risk assessment Integr Environ Assess Manage 5 62 68 10.1897/IEAM-2008-038.1 1:CAS:528:DC%2BD1MXit1Gkurs%3D
    • (2009) Integr Environ Assess Manage , vol.5 , pp. 62-68
    • Altenburger, R.1    Greco, W.R.2
  • 13
    • 66149106311 scopus 로고    scopus 로고
    • Interaction reaction
    • 10.1097/EDE.0b013e318197c0f5 19234409
    • JS Kaufman 2009 Interaction reaction Epidemiology 20 2 159 160 10.1097/EDE.0b013e318197c0f5 19234409
    • (2009) Epidemiology , vol.20 , Issue.2 , pp. 159-160
    • Kaufman, J.S.1
  • 14
    • 66149106310 scopus 로고    scopus 로고
    • When one depends on the other. Reporting of interaction in case-control and cohort studies
    • 10.1097/EDE.0b013e31818f6651 19034025
    • MJ Knol M Egger P Scott MI Geerlings JP Vandenbroucke 2009 When one depends on the other. Reporting of interaction in case-control and cohort studies Epidemiology 20 2 161 166 10.1097/EDE.0b013e31818f6651 19034025
    • (2009) Epidemiology , vol.20 , Issue.2 , pp. 161-166
    • Knol, M.J.1    Egger, M.2    Scott, P.3    Geerlings, M.I.4    Vandenbroucke, J.P.5
  • 15
    • 67349242369 scopus 로고    scopus 로고
    • Interactions in epidemiology: Relevance, identification, and estimation
    • 10.1097/EDE.0b013e318193e7b5 19234397
    • S Greenland 2009 interactions in epidemiology: relevance, identification, and estimation Epidemiology 20 1 14 17 10.1097/EDE.0b013e318193e7b5 19234397
    • (2009) Epidemiology , vol.20 , Issue.1 , pp. 14-17
    • Greenland, S.1
  • 16
    • 0021234395 scopus 로고
    • Drug combinations-concepts and terminology
    • HD Unkelbach T Wolf 1984 Drug combinations-concepts and terminology Arzneim Forsch 34 II 9 935 938
    • (1984) Arzneim Forsch , vol.342 , Issue.9 , pp. 935-938
    • Unkelbach, H.D.1    Wolf, T.2
  • 17
    • 34250958584 scopus 로고
    • Über Kombinationswirkungen I. Mitteilung: Hilfsmittel der Fragestellung
    • 10.1007/BF01952257 1:CAS:528:DyaB2sXitFCm
    • S Loewe H Muischnek 1926 Über Kombinationswirkungen I. Mitteilung: Hilfsmittel der Fragestellung Naunyn-Schmiedebergs Arch Exp Pathol u Pharmakol 114 313 326 10.1007/BF01952257 1:CAS:528:DyaB2sXitFCm
    • (1926) Naunyn-Schmiedebergs Arch Exp Pathol U Pharmakol , vol.114 , pp. 313-326
    • Loewe, S.1    Muischnek, H.2
  • 18
    • 84946384873 scopus 로고
    • The toxicity of poisons applied jointly
    • 10.1111/j.1744-7348.1939.tb06990.x 1:CAS:528:DyaH3cXhtFWq
    • CI Bliss 1939 The toxicity of poisons applied jointly Ann Appl Biol 26 585 615 10.1111/j.1744-7348.1939.tb06990.x 1:CAS:528:DyaH3cXhtFWq
    • (1939) Ann Appl Biol , vol.26 , pp. 585-615
    • Bliss, C.I.1
  • 19
    • 0002959791 scopus 로고
    • The analysis of toxicity tests on mixtures of poisons
    • 10.1111/j.1744-7348.1942.tb06923.x 1:CAS:528:DyaH38XksFaquw%3D%3D
    • DJ Finney 1942 The analysis of toxicity tests on mixtures of poisons Ann Apll Biol 29 82 94 10.1111/j.1744-7348.1942.tb06923.x 1:CAS:528: DyaH38XksFaquw%3D%3D
    • (1942) Ann Apll Biol , vol.29 , pp. 82-94
    • Finney, D.J.1
  • 20
    • 0000152236 scopus 로고
    • Statistical aspects of the independent joint action of poisons particularly insecticides. I. The toxicity of a mixture of poisons
    • 1:CAS:528:DyaH1MXhsF2msg%3D%3D 18121530
    • RL Plackett PS Hewlett 1948 Statistical aspects of the independent joint action of poisons particularly insecticides. I. The toxicity of a mixture of poisons Ann Appl Biol 35 347 358 1:CAS:528:DyaH1MXhsF2msg%3D%3D 18121530
    • (1948) Ann Appl Biol , vol.35 , pp. 347-358
    • Plackett, R.L.1    Hewlett, P.S.2
  • 21
    • 3543008788 scopus 로고
    • Quantal responses to mixtures of poisons under conditions of simple similar action. The analysis of uncontrolled data
    • JR Ashford 1958 Quantal responses to mixtures of poisons under conditions of simple similar action. The analysis of uncontrolled data Biometrika 45 74 88
    • (1958) Biometrika , vol.45 , pp. 74-88
    • Ashford, J.R.1
  • 22
    • 0001851294 scopus 로고
    • Toxicity of chemical mixtures
    • G.M. Rand S.R. Petrocelli (eds). Hemisphere Publishing Corporation Washington
    • Marking LL. Toxicity of chemical mixtures. In: Rand GM, Petrocelli SR, editors. Fundamentals of aquatic toxicology. Washington: Hemisphere Publishing Corporation; 1977.
    • (1977) Fundamentals of Aquatic Toxicology
    • Marking, L.L.1
  • 23
    • 0019517032 scopus 로고
    • Quantitative structure-activity relationships in fish toxicity studies Part 1: Relationship for 50 industrial pollutants
    • 10.1016/0300-483X(81)90130-X
    • H Könemann 1980 Quantitative structure-activity relationships in fish toxicity studies Part 1: relationship for 50 industrial pollutants Toxicology 19 209 221 10.1016/0300-483X(81)90130-X
    • (1980) Toxicology , vol.19 , pp. 209-221
    • Könemann, H.1
  • 24
    • 0000524515 scopus 로고
    • The toxicity to aquatic populations of mixtures containing certain heavy metals
    • 1:CAS:528:DyaE1cXlsFyht78%3D
    • PD Anderson LJ Weber 1975 The toxicity to aquatic populations of mixtures containing certain heavy metals Proc Int Conf Heavy Metals Environ 2 933 953 1:CAS:528:DyaE1cXlsFyht78%3D
    • (1975) Proc Int Conf Heavy Metals Environ , vol.2 , pp. 933-953
    • Anderson, P.D.1    Weber, L.J.2
  • 25
    • 0001967426 scopus 로고
    • Some comments on the assessment of joint action in herbicide mixtures
    • 1:CAS:528:DyaE1MXmslCqtA%3D%3D
    • PM Morse 1978 Some comments on the assessment of joint action in herbicide mixtures Weed Sci 26 1 58 71 1:CAS:528:DyaE1MXmslCqtA%3D%3D
    • (1978) Weed Sci , vol.26 , Issue.1 , pp. 58-71
    • Morse, P.M.1
  • 26
    • 0019750732 scopus 로고
    • Criteria for Analysing Interactions between biologically active agents
    • 10.1016/S0065-230X(08)60912-4 1:CAS:528:DyaL38Xps12isg%3D%3D 7041539
    • MC Berenbaum 1981 Criteria for Analysing Interactions between biologically active agents Adv Cancer Res 35 269 335 10.1016/S0065-230X(08) 60912-4 1:CAS:528:DyaL38Xps12isg%3D%3D 7041539
    • (1981) Adv Cancer Res , vol.35 , pp. 269-335
    • Berenbaum, M.C.1
  • 27
    • 0022266055 scopus 로고
    • A general noninteractive multiple toxicity model including probit, logit, and weibull transformations
    • 10.2307/2531291 1:STN:280:DyaL28%2Fnsl2nsA%3D%3D 4074820
    • ER Christensen CY Chen 1985 A general noninteractive multiple toxicity model including probit, logit, and weibull transformations Biometrics 41 711 725 10.2307/2531291 1:STN:280:DyaL28%2Fnsl2nsA%3D%3D 4074820
    • (1985) Biometrics , vol.41 , pp. 711-725
    • Christensen, E.R.1    Chen, C.Y.2
  • 28
    • 0024253724 scopus 로고
    • A straightforward method for the study of drug interactions: An isobolographic analysis primer
    • 1:CAS:528:DyaL1MXht1OqsLc%3D
    • PK Gessner 1988 A straightforward method for the study of drug interactions: an isobolographic analysis primer J Am Coll Toxicol 7 7 987 1012 1:CAS:528:DyaL1MXht1OqsLc%3D
    • (1988) J Am Coll Toxicol , vol.7 , Issue.7 , pp. 987-1012
    • Gessner, P.K.1
  • 30
    • 0000509587 scopus 로고
    • The employment of combinations of drugs in the chemotherapy of neoplasia: A review
    • 1:CAS:528:DyaG1cXis1Ohug%3D%3D 13460966
    • A Goldin N Mantel 1957 The employment of combinations of drugs in the chemotherapy of neoplasia: a review Cancer Res 17 7 635 654 1:CAS:528: DyaG1cXis1Ohug%3D%3D 13460966
    • (1957) Cancer Res , vol.17 , Issue.7 , pp. 635-654
    • Goldin, A.1    Mantel, N.2
  • 31
    • 77956164582 scopus 로고
    • Drug interactions Some first principles
    • Xintaras C, Johnson BL, deGroot C, editors Department of Health, Education and Welfare
    • Le Blanc AE. Drug interactions Some first principles. In: Xintaras C, Johnson BL, deGroot C, editors. Behavioral toxicology. US Government. Department of Health, Education and Welfare; 1974.
    • (1974) Behavioral Toxicology. US Government
    • Le Blanc, A.E.1
  • 32
    • 0000419454 scopus 로고
    • Die Mischarznei Versuch einer allgemeinen Pharmakologie der Arzneikombinationen
    • 10.1007/BF01890305
    • S Loewe 1927 Die Mischarznei Versuch einer allgemeinen Pharmakologie der Arzneikombinationen Klin Wochenschr 6 23 1077 1085 10.1007/BF01890305
    • (1927) Klin Wochenschr , vol.6 , Issue.23 , pp. 1077-1085
    • Loewe, S.1
  • 33
    • 0001593250 scopus 로고
    • Quantal responses to mixtures of poisons
    • RS Plackett PS Hewlett 1952 Quantal responses to mixtures of poisons J R Statist Soc B14 141 163
    • (1952) J R Statist Soc , vol.14 , pp. 141-163
    • Plackett, R.S.1    Hewlett, P.S.2
  • 34
    • 70449289547 scopus 로고
    • Randbemerkungen zur quantitativen Pharmakologie der Kombinationen
    • 1:STN:280:DyaF3c7ntVGqsg%3D%3D
    • S Loewe 1959 Randbemerkungen zur quantitativen Pharmakologie der Kombinationen Drug Res 9 449 456 1:STN:280:DyaF3c7ntVGqsg%3D%3D
    • (1959) Drug Res , vol.9 , pp. 449-456
    • Loewe, S.1
  • 35
    • 2642622348 scopus 로고
    • Pesticides interactions in higher plants
    • 1:CAS:528:DyaE2cXls1CntLY%3D
    • AR Putnam D Penner 1974 Pesticides interactions in higher plants Res Rev 50 73 110 1:CAS:528:DyaE2cXls1CntLY%3D
    • (1974) Res Rev , vol.50 , pp. 73-110
    • Putnam, A.R.1    Penner, D.2
  • 36
    • 0000994406 scopus 로고
    • Analysis of combined drug effects: A new look to a very old problem
    • 10.1016/0165-6147(83)90490-X
    • TC Chou P Talalay 1983 Analysis of combined drug effects: a new look to a very old problem Trends Pharmacol Sci 11 450 454 10.1016/0165-6147(83)90490-X
    • (1983) Trends Pharmacol Sci , vol.11 , pp. 450-454
    • Chou, T.C.1    Talalay, P.2
  • 37
    • 0026801038 scopus 로고
    • A proposal to define quality objectives for aquatic life for mixtures of chemical substances
    • 10.1016/0045-6535(92)90285-Y
    • D Calamari M Vighi 1992 A proposal to define quality objectives for aquatic life for mixtures of chemical substances Chemosphere 25 531 542 10.1016/0045-6535(92)90285-Y
    • (1992) Chemosphere , vol.25 , pp. 531-542
    • Calamari, D.1    Vighi, M.2
  • 38
    • 0033635575 scopus 로고    scopus 로고
    • Predictability of the toxicity of multiple chemical mixtures to Vibrio fischeri: Mixtures composed of similarly acting compounds
    • 1:CAS:528:DC%2BD3cXosVWjsrg%3D
    • R Altenburger T Backhaus W Boedeker M Faust M Scholze LH Grimme 2000 Predictability of the toxicity of multiple chemical mixtures to Vibrio fischeri: mixtures composed of similarly acting compounds Environ Toxicol Chem 19 2341 2347 1:CAS:528:DC%2BD3cXosVWjsrg%3D
    • (2000) Environ Toxicol Chem , vol.19 , pp. 2341-2347
    • Altenburger, R.1    Backhaus, T.2    Boedeker, W.3    Faust, M.4    Scholze, M.5    Grimme, L.H.6
  • 39
    • 0033636825 scopus 로고    scopus 로고
    • Predictability of the toxicity of a multiple mixture of dissimilarly acting chemicals to Vibrio fischeri
    • 1:CAS:528:DC%2BD3cXosVWjsrk%3D
    • T Backhaus R Altenburger E Boedeker M Faust M Scholze LH Grimme 2000 Predictability of the toxicity of a multiple mixture of dissimilarly acting chemicals to Vibrio fischeri Environ Toxicol Chem 19 2348 2356 1:CAS:528:DC%2BD3cXosVWjsrk%3D
    • (2000) Environ Toxicol Chem , vol.19 , pp. 2348-2356
    • Backhaus, T.1    Altenburger, R.2    Boedeker, E.3    Faust, M.4    Scholze, M.5    Grimme, L.H.6
  • 40
    • 0017360661 scopus 로고
    • Synergy, additivsm and antagonism in immunosuppression
    • 1:CAS:528:DyaE2sXkslyjt78%3D 324671
    • MC Berenbaum 1977 Synergy, additivsm and antagonism in immunosuppression Clin Exp Immunol 28 1 18 1:CAS:528:DyaE2sXkslyjt78%3D 324671
    • (1977) Clin Exp Immunol , vol.28 , pp. 1-18
    • Berenbaum, M.C.1
  • 41
    • 0019296817 scopus 로고
    • Bootstrapping a basic inequality in the analysis of joint action of two drugs
    • 10.2307/2556117 1:STN:280:DyaL3M3jtlWktg%3D%3D 7248434
    • J Wahrendorf CC Brown 1980 Bootstrapping a basic inequality in the analysis of joint action of two drugs Biometrics 36 653 657 10.2307/2556117 1:STN:280:DyaL3M3jtlWktg%3D%3D 7248434
    • (1980) Biometrics , vol.36 , pp. 653-657
    • Wahrendorf, J.1    Brown, C.C.2
  • 42
    • 0035142541 scopus 로고    scopus 로고
    • A general best-fit method for concentration-response curves and the estimation of low-effect concentrations
    • 1:CAS:528:DC%2BD3MXnsFSisg%3D%3D 11351447
    • M Scholze W Boedeker M Faust T Backhaus R Altenburger LH Grimme 2001 A general best-fit method for concentration-response curves and the estimation of low-effect concentrations Environ Toxicol Chem 20 448 457 1:CAS:528: DC%2BD3MXnsFSisg%3D%3D 11351447
    • (2001) Environ Toxicol Chem , vol.20 , pp. 448-457
    • Scholze, M.1    Boedeker, W.2    Faust, M.3    Backhaus, T.4    Altenburger, R.5    Grimme, L.H.6
  • 43
    • 0028991020 scopus 로고
    • Assessment of the combined effect of substances: The relationship between concentration addition and independent action
    • 10.2307/2532957
    • K Drescher W Boedeker 1995 Assessment of the combined effect of substances: the relationship between concentration addition and independent action Biometrics 51 716 730 10.2307/2532957
    • (1995) Biometrics , vol.51 , pp. 716-730
    • Drescher, K.1    Boedeker, W.2
  • 44
    • 0027761311 scopus 로고
    • Combined effects of toxicants: The need and soundness of assessment approaches in ecotoxicology
    • Boedeker W, Drescher K, Altenburger R, Faust M, Grimme LH. Combined effects of toxicants: the need and soundness of assessment approaches in ecotoxicology. Sci Total Environ. 1993;134 Suppl 2:931-938.
    • (1993) Sci Total Environ. , vol.134 , Issue.SUPPL. 2 , pp. 931-938
    • Boedeker, W.1    Drescher, K.2    Altenburger, R.3    Faust, M.4    Grimme, L.H.5
  • 45
    • 30644478790 scopus 로고    scopus 로고
    • Application and validation of approaches for the predictive hazard assessment of realistic pesticide mixtures
    • 10.1016/j.aquatox.2005.10.001 1:CAS:528:DC%2BD28Xjsl2quw%3D%3D
    • M Junghans T Backhaus M Faust M Scholze LH Grimme 2006 Application and validation of approaches for the predictive hazard assessment of realistic pesticide mixtures Aqua Toxicol 76 93 110 10.1016/j.aquatox.2005.10.001 1:CAS:528:DC%2BD28Xjsl2quw%3D%3D
    • (2006) Aqua Toxicol , vol.76 , pp. 93-110
    • Junghans, M.1    Backhaus, T.2    Faust, M.3    Scholze, M.4    Grimme, L.H.5
  • 46
    • 0016076701 scopus 로고
    • Synergy and antagonism in cause-effect relationships
    • 1:STN:280:DyaE2c3ntlOmtw%3D%3D
    • KJ Rothman 1974 Synergy and antagonism in cause-effect relationships Amer J Epidemiol 99 385 388 1:STN:280:DyaE2c3ntlOmtw%3D%3D
    • (1974) Amer J Epidemiol , vol.99 , pp. 385-388
    • Rothman, K.J.1
  • 47
    • 0017076295 scopus 로고
    • The estimation of synergy or antagonism
    • 1:STN:280:DyaE283gtlahtA%3D%3D
    • KJ Rothman 1976 The estimation of synergy or antagonism Amer J Epidemiol 103 506 511 1:STN:280:DyaE283gtlahtA%3D%3D
    • (1976) Amer J Epidemiol , vol.103 , pp. 506-511
    • Rothman, K.J.1
  • 48
    • 0018257769 scopus 로고
    • Additive, multiplicative, and other models for disease risks
    • 1:STN:280:DyaE1M%2FotVahsw%3D%3D 727202
    • SD Walter TR Holford 1978 Additive, multiplicative, and other models for disease risks Am J Epidemiol 108 341 346 1:STN:280:DyaE1M%2FotVahsw%3D%3D 727202
    • (1978) Am J Epidemiol , vol.108 , pp. 341-346
    • Walter, S.D.1    Holford, T.R.2
  • 49
    • 0019920462 scopus 로고
    • Causal and preventive interdependence. Elemetary principles
    • 1:STN:280:DyaL3s7hvFyiuw%3D%3D 7156935
    • OS Miettinen 1982 Causal and preventive interdependence. Elemetary principles Scand J Work Environ Health 8 159 168 1:STN:280:DyaL3s7hvFyiuw%3D%3D 7156935
    • (1982) Scand J Work Environ Health , vol.8 , pp. 159-168
    • Miettinen, O.S.1
  • 50
    • 0018964283 scopus 로고
    • Concepts of interaction
    • 1:STN:280:DyaL3M%2Fjs1OlsQ%3D%3D 7424895
    • KJ Rothman S Greenland AM Walker 1980 Concepts of interaction Am J Epidemiol 112 467 470 1:STN:280:DyaL3M%2Fjs1OlsQ%3D%3D 7424895
    • (1980) Am J Epidemiol , vol.112 , pp. 467-470
    • Rothman, K.J.1    Greenland, S.2    Walker, A.M.3
  • 52
    • 67349266632 scopus 로고    scopus 로고
    • Sufficient cause interactions and statistical interactions
    • 10.1097/EDE.0b013e31818f69e7 19234396
    • TJ VanderWeele 2009 Sufficient cause interactions and statistical interactions Epidemiology 20 1 6 13 10.1097/EDE.0b013e31818f69e7 19234396
    • (2009) Epidemiology , vol.20 , Issue.1 , pp. 6-13
    • Vanderweele, T.J.1
  • 53
    • 0023882628 scopus 로고
    • Invariants and noninvariants in the concept of interdependent effects
    • 1:STN:280:DyaL1c3msVarsQ%3D%3D 3387960
    • S Greenland C Poole 1988 Invariants and noninvariants in the concept of interdependent effects Scand J Work Environ Health 14 125 129 1:STN:280:DyaL1c3msVarsQ%3D%3D 3387960
    • (1988) Scand J Work Environ Health , vol.14 , pp. 125-129
    • Greenland, S.1    Poole, C.2
  • 54
    • 0018066012 scopus 로고
    • Interaction in epidemiologic studies
    • 1:STN:280:DyaE1M7gtFaisQ%3D%3D 736024
    • LL Kupper MD Hogan 1978 Interaction in epidemiologic studies Am J Epidemiol 108 447 453 1:STN:280:DyaE1M7gtFaisQ%3D%3D 736024
    • (1978) Am J Epidemiol , vol.108 , pp. 447-453
    • Kupper, L.L.1    Hogan, M.D.2
  • 55
    • 84982042971 scopus 로고
    • On the additive and multiplicative models of relative risk
    • 10.1002/bimj.4710310317
    • RL Kodell DW Gaylor 1989 On the additive and multiplicative models of relative risk Biom J 31 359 370 10.1002/bimj.4710310317
    • (1989) Biom J , vol.31 , pp. 359-370
    • Kodell, R.L.1    Gaylor, D.W.2
  • 56
    • 40349107178 scopus 로고    scopus 로고
    • Low-level exposure to multiple chemicals: Reasons fur human health concerns?
    • 10.1289/ehp.9358 18174958
    • A Kortenkamp M Faust M Scholze T Backhaus 2007 Low-level exposure to multiple chemicals: reasons fur human health concerns? Environ Health Perspect 115 Suppl 1 106 114 10.1289/ehp.9358 18174958
    • (2007) Environ Health Perspect , vol.115 , Issue.SUPPL. 1 , pp. 106-114
    • Kortenkamp, A.1    Faust, M.2    Scholze, M.3    Backhaus, T.4


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