Unusual cause of proteinuria and re-renal failure after kidney transplantation: De novo localized AL amyloidosis in renal allograft

International Urology and Nephrology

Volumn 42, Issue 2, 2010, Pages 507-511

  Chen, D J ^a   Jiang, H ^a   Yang, H ^a   He, Q ^a   Wang, H P ^a   Chen, J H ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

AL amyloidosis; Renal allograft; Renal transplantation; Transplant pathology

Indexed keywords

AMLODIPINE; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4; CREATININE; CYCLOSPORIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MYCOPHENOLIC ACID; PREDNISONE; TACROLIMUS;

ADULT; ARTICLE; CASE REPORT; CHINESE MEDICINE; CHRONIC GLOMERULONEPHRITIS; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; DOSE RESPONSE; DRUG DOSE REDUCTION; ELECTRON MICROSCOPY; HISTOLOGY; HUMAN; HUMAN TISSUE; HYPERTENSION; IMMUNOFLUORESCENCE; KIDNEY ALLOGRAFT; KIDNEY AMYLOIDOSIS; KIDNEY BIOPSY; KIDNEY FAILURE; KIDNEY FIBROSIS; KIDNEY GRAFT REJECTION; KIDNEY HYPERTROPHY; KIDNEY TRANSPLANTATION; MALE; PROTEINURIA; TREATMENT REFUSAL;

AMYLOIDOSIS; HUMANS; KIDNEY DISEASES; KIDNEY FAILURE; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; PROTEINURIA; RECURRENCE;

EID: 77956138979     PISSN: 03011623     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11255-009-9635-9     Document Type: Article

References (9)

1. Westermark P, Benson MD, Buxbaum JN et al (2007) A primer of amyloid nomenclature. Amyloid 14:179-183
2. Le QC, Wood TC, Alpers CE (1998) De novo AL amyloid in a renal allograft. Am J Nephrol 18:67-70
3. Hrncic R, Wall J, Wolfenbarger DA et al (2000) Antibodymediated resolution of light chain-associated amyloid deposits. Am J Pathol 157:1239-1246
4. Merlini G, Bellotti V (2003) Molecular mechanisms of amyloidosis. N Engl J Med 349:583-596
5. Kisilevsky R (2000) The relation of proteoglycans, serum amyloid P and apo E to amyloidosis current status, 2000. Amyloid 7:23-25
6. Tennent GA, Lovat LB, Pepys MB (1995) Serum amyloid P component prevents proteolysis of the amyloid fibrils of Alzheimer disease and systemic amyloidosis. Proc Natl Acad Sci USA 92:4299-4303
7. Sanchorawala V, Wright DG, Seldin DC et al (2001) An overview of the use of high-dose melphalan with autologous stem cell transplantation for the treatment of AL amyloidosis. Bone Marrow Transplant 28:637-642
8. Seldin DC, Anderson JJ, Sanchorawala V et al (2004) Improvement in quality of life of patients with AL amyloidosis treated with high-dose melphalan and autologous stem cell transplantation. Blood 104:1888-1893
9. Jaccard A, Moreau P, Leblond V et al (2007) High-dose melphalan versus melphalan plus dexamethasone for AL amyloidosis. N Engl J Med 357:1083-1093