Reaping the longevity dividend in time: Biogerontology heavyweights advocate seeking late-onset interventions against aging

Rejuvenation Research

Volumn 13, Issue 4, 2010, Pages 383-385

  De Grey, Aubrey D N J ^a  

^a SENS Foundation   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AGING; EDITORIAL; GERONTOLOGY; HEALTH CARE POLICY; HEALTH PROGRAM; HUMAN; LONGEVITY; MEDICAL RESEARCH; PRIORITY JOURNAL; PUBLIC FIGURE; REGENERATIVE MEDICINE;

GERIATRICS; HUMANS; LONGEVITY; PATIENT ADVOCACY;

EID: 77956131882     PISSN: 15491684     EISSN: None     Source Type: Journal    
DOI: 10.1089/rej.2010.1090     Document Type: Editorial

References (27)

1. Rae MR, Butler RN, Campisi J, de Grey ADNJ, Finch CE, Gough M, Martin GM, Vijg J, Perrott KM, Logan BJ. The demographic and biomedical case for late-life interventions in aging. Science Translational Medicine 2(40):21.
2. De Grey ADNJ. Man, machines, manufacturing, and maintenance: Merits of a much-maligned metaphor. Rejuvenation Res 2008;11:277-279.
3. De Grey ADNJ. Long live the unreasonable man. Rejuvenation Res 2008;11:541-542.
4. De Grey ADNJ. The Einsteinian imperative. Rejuvenation Res 2009;12:383-385.
5. De Grey ADNJ. The curiously misunderstood role of evidence in designing new technology. Rejuvenation Res 2009;12:75-76.
6. Partridge B, Lucke J, Bartlett H, Hall W. Ethical, social, and personal implications of extended human lifespan identified by members of the public. Rejuvenation Res 2009;12:351-357.
7. Warner HR. Making the political case for biogerontology funding: A view from the trenches. Rejuvenation Res 2008; 11:485-488.
8. Lederman S. American Federation for Aging Research: Interview with Stephanie Lederman. Interview by Vicki Gla-ser. Rejuvenation Res 2009;12:155-157.
9. Butler RN. Interview with Robert Butler, M.D. Interview by Vicki Glaser. Rejuvenation Res 2008;11:977-980.
10. Jaenisch R. Interview with Rudolf Jaenisch, M.D. Interview by Vicki Glaser. Rejuvenation Res 2008;11:849-850.
11. Blackburn E. Interview with Elizabeth Blackburn, Ph.D. Interview by Vicki Glaser. Rejuvenation Res 2008;11:701-705.
12. Miller RA, Harrison DE, Astle CM, Floyd RA, Flurkey K, Hensley KL, Javors MA, Leeuwenburgh C, Nelson JF, On-gini E, Nadon NL, Warner HR, Strong R. An aging interventions testing program: Study design and interim report. Aging Cell 2007; 6: 565-575.
13. Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, Flurkey K, Nadon NL, Wilkinson JE, Frenkel K, Carter CS, Pahor M, Javors MA, Fernandez E, Miller RA. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 2009; 460: 392-395.
14. Blagosklonny MV. Aging, stem cells, and mammalian target of rapamycin: a prospect of pharmacologic rejuvenation of aging stem cells. Rejuvenation Res 2008;11:801-808.
15. De Grey ADNJ. Curiosity is addictive, and this is not an entirely good thing. Rejuvenation Res 2008;11:1-3.
16. Abramovich A, Muradian KK, Fraifeld VE. Have we reached the point for in vivo rejuvenation? Rejuvenation Res 2008;11:489-492.
17. Lee SJ, Van Dyke M, Atala A, Yoo JJ. Host cell mobilization for in situ tissue regeneration. Rejuvenation Res 2008;11:747-756.
18. Kurz T. Can lipofuscin accumulation be prevented? Rejuvenation Res 2008;11:441-443.
19. Lee SJ, Van Dyke M, Atala A, Yoo JJ. Host cell mobilization for in situ tissue regeneration. Rejuvenation Res 2008;11:747-756.
20. Okarma T. Interview with Thomas Okarma, M.D., Ph.D.; CEO, Geron. Interview by Vicki Glaser. Rejuvenation Res 2009;12:295-300.
21. Sinclair DA. Interview with David A. Sinclair, Ph.D. Interview by Vicki Glaser. Rejuvenation Res 2008;11:265-268.
22. Chen J, Velalar CN, Ruan R. Identifying the changes in gene profiles regulating the amelioration of age-related oxidative damages in kidney tissue of rats by the intervention of adult-onset calorie restriction. Rejuvenation Res 2008;11:757-763.
23. Froy O, Chapnik N, Miskin R. Relationship between calorie restriction and the biological clock: Lessons from long-lived transgenic mice. Rejuvenation Res 2008;11:467-471.
24. Goertzel B, Pennachin C, de Alvarenga Mudado M, de Souza Coelho L. Identifying the genes and genetic interrelationships underlying the impact of calorie restriction on maximum lifespan: an artificial intelligence-based approach. Rejuvenation Res 2008;11:735-748.
25. Hipkiss AR. On methionine restriction, suppression of mi-tochondrial dysfunction and aging. Rejuvenation Res 2008;11:685-688.
26. Hofer T, Fontana L, Anton SD, Weiss EP, Villareal D, Ma-layappan B, Leeuwenburgh C. Long-term effects of caloric restriction or exercise on DNA and RNA oxidation levels in white blood cells and urine in humans. Rejuvenation Res 2008;11:793-799.
27. Brindley D, Davie N. Regenerative medicine through a crisis: social perception and the financial reality. Rejuvenation Res 2009;12:455-461.