Incidence and outcome of nasal and groin methicillin-resistant staphylococcus aureus carrier state in patients admitted for routine cardiac surgery

JPMI - Journal of Postgraduate Medical Institute

Volumn 22, Issue 1, 2008, Pages 21-26

  Mohammad, Zahidullah ^a   Yasin, Khan ^a   Niaz, Ali ^a   Aurangzeb, Durrani ^a   Mohammad, Khan Amir ^a   Mohammad, Rehman ^a  

^a REHMAN MEDICAL INSTITUTE   (Pakistan)

Author keywords

Cardiac surgery; MRSA carriers; Wound infection

Indexed keywords

OXACILLIN;

ADOLESCENT; ADULT; AGED; ANTIBIOTIC SENSITIVITY; ARTERY LIGATION; ARTICLE; BACTERIUM CARRIER; BACTERIUM IDENTIFICATION; CHILD; CONTROLLED STUDY; CORONARY ARTERY BYPASS SURGERY; CULTURE MEDIUM; DIABETIC PATIENT; DISK DIFFUSION; FEMALE; HEART SURGERY; HEART VALVE SURGERY; HIGH RISK POPULATION; HUMAN; INGUINAL REGION; MAJOR CLINICAL STUDY; MALE; MEDIASTINITIS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; NONHUMAN; NOSE SMEAR; OPEN HEART SURGERY; PAKISTAN; PERICARDIECTOMY; PRESCHOOL CHILD; SCHOOL CHILD; STERNOTOMY; SURGICAL INFECTION; BACTERIUM CULTURE; HOSPITAL ADMISSION; INCIDENCE; NOSE; OUTCOME ASSESSMENT; POSTOPERATIVE INFECTION; PREOPERATIVE PERIOD; SURGICAL PATIENT;

EID: 77956123596     PISSN: 10135472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Bratzler DW, Houck PM. Antimicrobial prophylaxis for surgery: An advisory statement from the National Surgical Infection Prevention Project. Clin Infect Dis 2004:38:1706-15.
2. Demmy TL, Park SB, Liebler GA, Burkholder JA, Maher TD, Benckart DH, et al. Recent experience with major sternal wound complications. Ann Thorac Surg 1990;49:458-62.
3. Tang GHL, Maganti M, Weisel RD, Borger MA. Prevention and management of deep sternal wound infection. Sem Thorac Cardiovasc Surg 2004;16:62-9.
4. Braxton JH, Marrin CAS, McGrath PD, Morton JR, Norotsky M, Charlesworth DC, et al. 10-year follow-up of patients with and without mediastinitis. Sem Thorac Cardiovasc Surg 2004;16:70-6.
5. Baskett RJ, MacDougall CE, Ross DB. Is mediastinitis a preventable complication? A 10-year review. Ann Thorac Surg 1999;67:462-5.
6. Abboud SC, Wey SB, Baltar VT. Risk factors for mediastinitis after cardiac surgery. Ann Thorac Surg 2002;77:676-83.
7. Crabtree TD, Codd JE, Fraser VJ, Bailey MS, Olsen MA, Damiano RJ. Multivariate analysis of risk factors for deep and superficial sternal infection after coronary artery bypass grafting at a tertiary care medical center. Sem Thorac Cardiovasc Surg 2004;16:53-61.
8. Olsen MA, Lock-Buckley P, Hopkins D, Polish LB, Sundt TM, Fraser VJ. The risk factors for deep and superficial chest surgical-site infections after coronary artery bypass graft surgery are different. J Thorac Cardiovasc Surg 2002;124:136-45.
9. Gardlund B, Bitkover CY, Vaage J. Postoperative mediastinitis in cardiac surgery: Microbiology and pathogenesis. Eur J Cardiothorac Surg 2002;21:825-30.
10. Siegman-Igra Y, Shafir R, Weiss J, Herman O, Schwartz D, Konforti N. Serious infectious complications of midsternotomy: A review of bacteriology and antimicrobial therapy. Scand J Infect Dis 1990;22:633-43.
11. Cheng-Hsin L, Ron-Bin H, Shan-Chwen C, Fang-Yue L, Shu-Hsun C. Poststernotomy mediastinitis due to Methicillin-resistant staphylococcus aureus endemic in a hospital. Clin Infect Dis 2003;37:679-84.
12. Kluytmans JA, Mouton JW, Ijzerman EPF, Vandenbroucke-Grauls CMJE, Maat AWPM, Wagenvoort JAT, et al. Nasal carriage of Staphylococcus aureus as a major risk factor for wound infections after cardiac surgery. J Infect Dis 1995;171:216-9.
13. Cimochowski GE, Harostock MD, Brown R, Bernardi M, Alonzo N, Coyle K. Intranasal mupirocin reduces sternal wound infection after open heart surgery in diabetics and nondiabetics. Ann Thorac Surg 2001;71:1572-9.
14. Cookson BD. The emergence of mupirocin resistance: A challenge to infection control and antibiotic prescribing practice. J Antimicrob Chemother 1998;41:11-8.
15. Mekontso-Dessap A, Kirsch M, Brun-Buisson C, Loisance D. Poststernotomy mediastinitis due to Staphylococcus aureus: Comparison between Methicillin-resistant and Methicillin- susceptible cases. Clin Infect Dis 2001;32:877-83.
16. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing. Sixteenth informational supplement. M100-516. Wayne, PA:CLSI:2006.
17. Kluytmans J, Belkum AV, Verbrugh H. Nasal carriage of Staph y lococcus aureus: Epidemiology, underlying mechanism, and associated risks. Clinic Microbiol Rev. 1997 July, p. 505-20.
18. Jevons MP. Celbenin-resistant staphylococci. Br Med J 1961;1:124-5.
19. Nick JM. Surgical site infections. In: Beard JD, Murray S, editors. Pathways of care in vascular surgery. tfm Publishing Limited, 2002:307-314.
20. Davis KA, Stewart JJ, Crouch HK, Florez CE, Hospenthal DR. Methicillin-resistant Staphylococcus aureus (MRSA) nares colonization at hospital admission and its effects on subsequent MRSA infection. Clin Infect Dis 2004;39:776-82.
21. Hidron AI, Kourbatova EV, Halvosa JS, Terrell BJ, McDougal LK, Tenover FC, et al. Risk factors for colonization with methicillin- resistant Staphylococcus aureus (MRSA) in patients admitted to an urban hospital: emergence of community-associated MRSA nasal carriage. Clin Infect Dis 2005;41:159-66.
22. Finkelstein R, Rabino G, Mashiah T, Bar-El Y, Alder Z, Kertzman V, et al. Vancomycin versus cefazolin prophylaxis for cardiac surgery in the setting of a high prevalence of methicillin-resistant staphylococcus infections. J Thorac Cardiovasc Surg. 2002;123:326-32.
23. Dodds Ashley ES, Carroll DN, Engemann JJ, Harris AD, Fowler Jr. VG, Sexton DJ, Kaye K S. Risk factors for post operative mediastinitis due to Methicillin-resistant Staphylococcus aureus. Clin Infect Dis 2004;38:1555-60.
24. Casewell MW. The nose: An underestimated source of Staphylococcus aureus causing wound infection. J Hosp Infect 1998;40:S3-11.
25. White A. Increased infection rates in heavy nasal car rier s o f c o a gu l a se- po siti v e staphylococci. Antimicrob Agents Chemother 1963;30:667-70.
26. Archer TB. Prevention of health care- associated methicillin-resistant Staphylococcus aureus infections: adapting to a changing epidemiology. Clin Infect Dis 2005:41:167-9.
27. Muto C, Jernigan JA, Ostrowsky BE, Richet HM, Jarvis WR, Boyce JM, et al. SHEA guidelines for preventing nosocomial transmission of multidrug-resistant strains of Staphylococcus aureus and enterococcus. Infect Control Hosp Epidemiol 2003;24:362-86.
28. Maki DG, Bohn MJ, Stolz SM, Kroncke GM, Acher CW, Myerowitz DP. Comparative study of cefazolin, cefamandole, and vancomycin for surgical prophylaxis in cardiac and vascular operations. A double-blind randomized trial. J Thorac Cardiovasc Surg 1992;104:1423-34.
29. Chenoweth CE, DePestel DD, Prager RL. Are cephalosporins adequate for antimicrobial prophylaxis for cardiac surgery involving implants? Clin Infect Dis 2005;41:122-3.