Polymorphisms in GDF9 and BMP15 associated with fertility and ovulation rate in moghani and ghezel sheep in Iran

Reproduction in Domestic Animals

Volumn 45, Issue 4, 2010, Pages 666-669

  Barzegari, A ^a   Atashpaz, S ^b   Ghabili, K ^b   Nemati, Z ^b,c   Rustaei, M ^d   Azarbaijani, R ^e  

^a Agricultural Biotechnology Research Institute for Northwest and West of Iran   (Iran)

^b UNIVERSITY OF TABRIZ   (Iran)

^c Young Researchers' Club   (Iran)

^d URMIA UNIVERSITY   (Iran)

^e Sari University of Agricultural Sciences and Natural Resources   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 15; DNA; GROWTH DIFFERENTIATION FACTOR 9;

ANIMAL; ARTICLE; BREEDING; FEMALE; FERTILITY; GENETIC POLYMORPHISM; GENETICS; GENOTYPE; IRAN; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; OVULATION; PHYSIOLOGY; POINT MUTATION; SHEEP;

ANIMALS; BASE SEQUENCE; BONE MORPHOGENETIC PROTEIN 15; BREEDING; DNA; FEMALE; FERTILITY; GENOTYPE; GROWTH DIFFERENTIATION FACTOR 9; IRAN; MOLECULAR SEQUENCE DATA; OVULATION; POINT MUTATION; POLYMORPHISM, GENETIC; SHEEP;

OVIS ARIES;

EID: 77956108390     PISSN: 09366768     EISSN: 14390531     Source Type: Journal    
DOI: 10.1111/j.1439-0531.2008.01327.x     Document Type: Article

References (13)

1. Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 1997, 25:3389-3402.
2. Atashpaz S, Barzegari A, Azarbaijani R. General DNA Extraction Kit 2008, Iranian Patent Office No.48024, Tehran, Iran
3. Bodin L, Di Pasquale E, Fabre S, Bontoux M, Monget P, Persani L, Mulsant P. A novel mutation in the Bone Morphogenetic Protein 15 Gene causing defective protein secretion is associated with both increased ovulation rate and sterility in Lacaune sheep. Endocrinology 2007, 148:393-400.
4. Davis GH. Major genes affecting ovulation rate in sheep. Genet Sel Evol 2005, 37(Suppl. 1):S11-S23.
5. Galloway SM, McNatty KP, Cambridge LM, Laitinen MP, Juengel JL, Jokiranta TS, McLaren RJ, Luiro K, Dodds KG, Montgomery GW, Beattie AE, Davis GH, Ritvos O. Mutations in an oocyte-derived growth factor gene (BMP15) cause increased ovulation rate and infertility in a dosage-sensitive manner. Nat Genet 2000, 25:279-283.
6. Galloway SM, Gregan SM, Wilson T, McNatty KP, Juengel JL, Ritvos O, Davis GH. Bmp15 mutations and ovarian function. Mol Cell Endocrinol 2002, 191:15-18.
7. Gemmell NJ, Slate J. Heterozygote advantage for fecundity. PLoS ONE 2006, 1:e125.
8. Hanrahan JP, Gregan SM, Mulsant P, Mullen M, Davis GH, Powell R, Galloway SM. Mutations in the genes for oocyte-derived growth factors GDF9 and BMP15 are associated with both increased ovulation rate and sterility in Cambridge and Belclare sheep (Ovis aries). Biol Reprod 2004, 70:900-909.
9. Mason IL. A World Dictionary of Livestock Breeds, Types and Varieties 1996, 4th edn, CAB International, Wallingford, UK, pp
10. Monteagudo LV, Ponz R, Tejedor MT, Laviña A, Sierra I. A 17bp deletion in the Bone Morphogenetic Protein 15 (BMP15) gene is associated to increased prolificacy in the Rasa Aragonesa sheep breed. Anim Reprod Sci 2009, 110:139-146.
11. Nooriyan sooror E. Ghezel or Red Karaman 2000, http://www.ansi.okstate.edu/breeds/sheep/ghezel/index.htm, Department of Animal Sciences at Oklahoma State University, ; accessed 13 October 2008
12. Notter DR. Genetic aspects of reproduction in sheep. Reprod Domest Anim 2008, 43(Suppl. 2):122-128.
13. Shimasaki S, Moore RK, Otsuka F, Erickson GF. The bone morphogenetic protein system in mammalian reproduction. Endocr Rev 2004, 25:72-101.