Detection of elevated serum levels of the chemokine CCL18 in B-cell chronic lymphocytic leukaemia: Identification of a novel biomarker

Acta Haematologica

Volumn 124, Issue 2, 2010, Pages 110-114

  Schröttner, Percy ^a   Wollner, Stefan ^a   Catusse, Julie ^a   Burger, Meike ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 MICROGLOBULIN; BIOLOGICAL MARKER; CCL1 CHEMOKINE; CD38 ANTIGEN; CHEMOKINE RECEPTOR; PROTEIN CCL18; PROTEIN KINASE ZAP 70; UNCLASSIFIED DRUG; BETA CHEMOKINE; CCL18 PROTEIN, HUMAN; TUMOR MARKER;

ARTICLE; CANCER REGRESSION; CANCER STAGING; CENTRIFUGATION; CHRONIC LYMPHATIC LEUKEMIA; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HEMATOLOGIC DISEASE; HEMATOPOIESIS; HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; BLOOD; CELL CULTURE; FEMALE; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MALE; PROGNOSIS;

BETA 2-MICROGLOBULIN; CELLS, CULTURED; CHEMOKINES, CC; FEMALE; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MALE; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 77956068023     PISSN: 00015792     EISSN: None     Source Type: Journal    
DOI: 10.1159/000317751     Document Type: Article

References (15)

1. Murphy PM, Baggiolini M, Charo IF, Hebert CA, Horuk R, Matsushima K, Miller LH, Oppenheim JJ, Power CA: International union of pharmacology. 22. Nomenclature for chemokine receptors. Pharmacol Rev 2000; 52:145-176.
2. Pals ST, de Gorter DJ, Spaargaren M: Lym-phoma dissemination: the other face of lymphocyte homing. Blood 2007; 110:3102-3111.
3. Burger JA, Kipps TJ: Chemokine receptors and stromal cells in the homing and homeo-stasis of chronic lymphocytic leukemia B cel ls. Leu k Lymphoma 20 02; 43: 461-466.
4. Burger JA, Tsukada N, Burger M, Zvaifler NJ, Dell'Aquila M, Kipps TJ: Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1. Blood 2000; 96: 2655-2663.
5. Ghobrial IM, Bone ND, Stenson MJ, Novak A, Hedin KE, Kay NE, Ansell SM: Expression of the chemokine receptors CXCR4 and CCR7 and disease progression in B-cell chronic lymphocytic leukemia/small lym-phocytic lymphoma. Mayo Clin Proc 2004; 79: 318-325.
6. Wimmer A, Khaldoyanidi SK, Judex M, Se-robyan N, Discipio RG, Schraufstatter IU: CCL18/PARC stimulates hematopoiesis in long-term bone marrow cultures indirectly through its effect on monocytes. Blood 2006; 10 8: 3722-3729.
7. Schutyser E, Richmond A, Van Damme J: Involvement of CC chemokine ligand 18 (CCL18) in normal and pathological processes. J Leukoc Biol 2005; 78:14-26.
8. Wierda WG, O'Brien S, Wang X, Faderl S, Ferrajoli A, Do KA, Garcia-Manero G, Cortes J, Thomas D, Koller C, Burger J, Lerner S, Kantarjian H, Keating M: Characteristics associated with important clinical end points in patients with chronic lymphocytic leukemia at initial treatment. J Clin Oncol 2009; 27:1637-1643.
9. Struyf S, Schutyser E, Gouwy M, Gijsbers K, Proost P, Benoit Y, Opdenakker G, Van Da mme J, Laure ys G: PA RC/CCL18 is a plasma CC chemokine with increased levels in childhood acute lymphoblastic leukemia. Am J Pathol 2003; 163:2065-2075.
10. Ghia P, Circosta P, Scielzo C, Vallario A, Camporeale A, Granziero L, Caligaris-Cap-pio F: Differential effects on CLL cell survival exerted by different microenvironmental elements. Curr Top Microbiol Immunol 2005; 294:135-145.
11. Adema GJ, Hartgers F, Verstraten R, de Vries E , Marland G, Menon S , Foster J, Xu Y, Nooy-en P, McClanahan T, Bacon KB, Figdor CG: A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells. Nature 1997; 387:713-717.
12. Pivarcsi A, Gombert M, Dieu-Nosjean MC, Lauerma A, Kubitza R, Meller S, Rieker J, Muller A, Da Cunha L, Haahtela A, Sonkoly E, Fridman WH, Alenius H, Kemeny L, Ru-zicka T, Zlotnik A, Homey B: CC chemokine ligand 18, an atopic dermatitis-associated and dendritic cell-derived chemokine, is regulated by staphylococcal products and allergen exposure. J Immunol 2004; 173 : 5810-5817.
13. Younes A, Snell V, Consoli U, Clodi K, Zhao S, Palmer JL, Thomas EK, Armitage RJ, An-dreeff M: Elevated levels of biologically active soluble CD40 ligand in the serum of patients with chronic lymphocytic leukaemia. Br J Haematol 1998; 100:135-141.
14. Schutyser E, Struyf S, Proost P, Opdenakker G, Laureys G, Verhasselt B, Peperstraete L, Van de Putte I, Saccani A, Allavena P, Man-tovani A, Van Damme J: Identification of biologically active chemokine isoforms from ascitic fluid and elevated levels of CCL18/ pulmonary and activation-regulated chemo-kine in ovarian carcinoma. J Biol Chem 2002; 277:24584-24593.
15. Leung SY, Yuen ST, Chu KM, Mathy JA, Li R, Chan AS, Law S, Wong J, Chen X, So S: Expression profiling identifies chemokine (C-C motif) ligand 18 as an independent prognostic indicator in gastric cancer. Gas-troenterology 2004; 127:457-469.