Tetracycline and penicillin resistant Clostridium perfringens isolated from the fangs and venom glands of Loxosceles laeta: Its implications in loxoscelism treatment

Toxicon

Volumn 56, Issue 6, 2010, Pages 890-896

  Catalan A ^a   Espoz, M C ^a   Cortes W ^a   Sagua, H ^a   Gonzalez J ^a   Araya, J E ^a  

^a UNIVERSIDAD DE ANTOFAGASTA   (Chile)

Author keywords

Lactamase; Antimicrobial resistance; Clostridium perfringens; Loxosceles laeta; Tetracycline

Indexed keywords

AMPICILLIN; BETA LACTAMASE; CHLORAMPHENICOL; CLINDAMYCIN; ERYTHROMYCIN; GENTAMICIN; PENICILLIN G; SPIDER VENOM; TETRACYCLINE;

ANIMAL EXPERIMENT; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATION; CLOSTRIDIUM PERFRINGENS; CONTROLLED STUDY; ENVENOMATION; FANG; IN VIVO STUDY; LOXOSCELES LAETA; LOXOSCELISM; MALE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RABBIT; SALIVARY GLAND; SKIN NECROSIS; SPIDER; TOOTH; VENOM GLAND;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIVENINS; ARACHNIDISM; BETA-LACTAMASES; CLOSTRIDIUM PERFRINGENS; EXOCRINE GLANDS; GENE EXPRESSION; INJECTIONS, INTRADERMAL; MALE; NECROSIS; PENICILLIN RESISTANCE; PENICILLINS; PHOSPHORIC DIESTER HYDROLASES; RABBITS; SKIN; SPIDER VENOMS; SPIDERS; TETRACYCLINE; TETRACYCLINE RESISTANCE; TOOTH;

ARANEAE; BACTERIA (MICROORGANISMS); CLOSTRIDIUM; CLOSTRIDIUM PERFRINGENS; LOXOSCELES; LOXOSCELES INTERMEDIA; LOXOSCELES LAETA; ORYCTOLAGUS CUNICULUS;

EID: 77956058587     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2010.06.012     Document Type: Article

References (36)

1. Alexander C.J., Citron D.M., Brazier J.S., Goldstein E.J.C. Identification and antimicrobial resistance patterns of clinical isolates of Clostridium clostridioforme, Clostridium innocuum, and Clostridium ramosum compared with those of clinical isolates of Clostridium perfringens. J. Clin. Microbiol. 1995, 33:3209-3215.
2. Allen S.D., Emery C.L., Siders J.A. Clostridium. Manual of Clinical Microbiology 1999, 654-671. American Society for Microbiology, Washington, DC. seventh ed. P.R. Murray, E.J. Baron, M.A. Pfaller, F.C. Tenover, R.H. Yolken (Eds.).
3. Brazier J.S., Levett P.N., Stannard A.J., Phillips K.D., Willis A.T. Antibiotic susceptibility of clinical isolates of clostridia. J. Antimicrob. Chemother. 1985, 15:181-185.
4. Bücherl W. Biology and venoms of the most important South American spiders of the genera Phoneutria, Loxosceles, Lycosa, and Latrodectus. Am. Zool. 1969, 9:157-159.
5. Burgen A.S., Dickens F., Zatman L.J. The action of botulinum toxin on the neuro-muscular junction. J. Physiol. 1949, 109:10-24.
6. Dornbusch K., Nord C.E., Dahlback A. Antibiotic susceptibility of Clostridium species isolated from human infections. Scand. J. Infect. Dis. 1975, 7:127-134.
7. Dutta G.N., Devriese L.A. Macrolide-lincosamide-streptogramin resistance patterns in Clostridium perfringens from animals. Antimicrob. Agents Chemother. 1981, 19:274-278.
8. Futrell J.M. Loxoscelism. Am. J. Med. Sci. 1992, 304:261-267.
9. Hecht D.W. Anaerobes: antibiotic resistance, clinical significance, and the role of susceptibility testing. Anaerobe 2006, 12:115-121.
10. Hogan C.J., Barbaro K.C., Winkel K. Loxoscelism: old obstacles, new directions. Ann. Emerg. Med. 2004, 44(6):608-622.
11. Johanesen P.A., Lyras D., Bannam T.L., Rood J.I. Transcriptional analysis of the tet(P) operon from Clostridium perfringens. J. Bacteriol. 2001, 183:7110-7119.
12. Johansson A., Greko C., Engstrom B.E., Karlsson M. Antimicrobial susceptibility of Swedish, Norwegian and Danish isolates of Clostridium perfringens from poultry, and distribution of tetracycline resistance genes. Vet. Microbiol. 2004, 99:251-257.
13. Lyras D., Rood J.L. Genetic organization and distribution of tetracycline resistance determinants in Clostridium perfringens. Antimicrob. Agents Chemother. 1996, 40:2500-2504.
14. McDonel J.L. Clostridium perfringens toxins (type A, B, C, D, E). Pharmacol. Ther. 1980, 10:617-635.
15. Middlebrook J.L., Dorland B. Bacterial toxins: cellular mechanisms of action. Microbiol. Rev. 1984, 48:199-221.
16. Monteiro C.L.B., Rubel R., Cogo L.L., Mangili O.C., Gremski W., Veiga S.S. Isolation and identification of Clostridium perfringens in the venom and fangs of Loxosceles intermedia: enhancement of the demonecrotic lesion in loxoscelism. Toxicon 2002, 40:409-418.
17. Murphy T.F., Barza M., Park J.T. Penicillin-binding proteins in Clostridium perfringens. Antimicrob. Agents Chemother. 1981, 20:809-813.
18. Murray P.R., Rosenthal K.S., Kobayashi G.S., Pfaller M.A. Medical Microbiology 2000, 3r, American Society for Microbiology, Washington, pp. 654-671.
19. Myers G.S.A., Titball R.W., Rood J.I., Melville S.B., Paulsen I.T., et al. Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens. Genome Res. 2006, 16:1031-1040.
20. NCCLS Methods for Antimicrobial Susceptibility Testing of Anaerobic Bacteria 2001, Approved Standard M11-A5, National Committee for Clinical Laboratory Standards, Wayne, PA. fifth ed.
21. Paixão-Cavalcante D., van den Berg C.W., Gonçalves-de-Andrade R.M., Fernandes-Pedrosa M.F., Okamoto C.K., Tambourgi D.V. Tetracycline protects against dermonecrosis induced by Loxosceles spider venom. J. Invest. Dermatol. 2007, 127:1410-1418.
22. Ríos J.C., Paris E., Apt W., Ristori L., Ramírez G. Guía clínica para el manejo de la mordedura de araña de rincón. Loxosceles laeta 2004, Centro de Información Toxicológica Pontificia Universidad Católica de Chile (CITUC), Santiago, Chile.
23. Ríos J.C., Pérez M., Sánchez P., Bettini M., Mieres J.J., Paris E. Caracterización clínico-epidemiológica telefónica de la mordedura por araña de rincón, en un centro de información toxicológica de Chile, durante el año 2005. Rev. Méd. Chile 2007, 135:1160-1165.
24. Rood J.I., Cole S.T. Molecular genetics and pathogenesis of Clostridium perfringens. Microbiol. Rev. 1991, 55:621-648.
25. Rood J.I., Maher E.A., Somers E.B., Campos E., Duncan C.L. Isolation and characterization of multiply antibiotic-resistant Clostridium perfringens strains from porcine feces. Antimicrob. Agents Chemother. 1978, 13:871-880.
26. Rood J.I., Scott V.N., Duncan C.L. Identification of a transferable tetracycline resistance plasmid (pCW3) from Clostridium perfringens. Plasmid 1978, 1:563-570.
27. Rotilie C.A., Fass R.J., Prior R.B., Perkins R.L. Microdilution technique for antimicrobial susceptibility testing of anaerobic bacteria. Antimicrob. Agents Chemother. 1975, 7:311-315.
28. Sasaki Y., Yamamoto K., Tamura Y., Takahashi T. Tetracycline-resistance genes of Clostridium perfringens, Clostridium septicum and Clostridium sordellii isolated from cattle affected with malignant edema. Vet. Microbiol. 2001, 83:61-69.
29. Schenone F.H. Toxic pictures produced by spider bites in Chile: latrodectism and loxoscelism. Rev. Méd. Chile 2003, 131(4):437-444.
30. Schenone F.H., Rubio A.S., Saavedra U.T., Rojas S.A. Loxoscelismo en pediatría: región Metropolitana, Chile. Rev. Chil. Pediatr. 2001, 72(2):100-109.
31. Schwartzman J.D., Reller L.B., Wang W.L. Susceptibility of Clostridium perfringens isolated from human infections to twenty antibiotics. Antimicrob. Agents Chemother. 1977, 11(4):695-697.
32. Shoemaker N.B., Vlamakis H., Hayes K., Salyers A.A. Evidence for extensive resistance gene transfer among Bacteroides spp. and among Bacteroides and other genera in the human colon. Appl. Environ. Microbiol. 2001, 67:561-568.
33. da Silva P.H., da Silveira R.B., Appel M.H., Mangili C.O., Gremski W., Veiga S.S. Brown spiders and loxoscelim. Toxicon 2004, 44:693-709.
34. Smith L.D.S. Virulence factors of Clostridium perfringens. Rev. Infect. Dis. 1979, 1:254-260.
35. Songer J.G. Bacterial phospholipases and their role in virulence. Trends Microbiol. 1997, 5:156-161.
36. Williamson R. Resistance of Clostridium perfringens to beta-lactam antibiotics mediated by a decreased affinity of a single essential penicillin-binding protein. J. Gen. Microbiol. 1983, 129:2339-2343.