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Volumn 95, Issue 8, 2010, Pages 1415-1419

The response to imatinib and interferon-α is more rapid than the response to imatinib alone: A retrospective analysis of 495 philadelphia-positive chronic myeloid leukemia patients in early chronic phase

(20)  Palandri, Francesca a   Castagnetti, Fausto a   Iacobucci, Ilaria a   Martinelli, Giovanni a   Amabile, Marilina a   Gugliotta, Gabriele a   Poerio, Angela a   Testoni, Nicoletta a   Breccia, Massimo b   Bocchia, Monica c   Crugnola, Monica d   Rege Cambrin, Giovanna e   Martino, Bruno f   Pierri, Ivana g   Radaelli, Franca h   Specchia, Giorgina i   Pane, Fabrizio j   Saglio, Giuseppe e   Rosti, Gianantonio a   Baccarani, Michele a  


Author keywords

Chronic myeloid leukemia; Imatinib; Interferon ; Molecular response

Indexed keywords

BCR ABL PROTEIN; IMATINIB; PEGINTERFERON ALPHA2B;

EID: 77956035133     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2009.021246     Document Type: Article
Times cited : (44)

References (27)
  • 1
    • 18144451171 scopus 로고    scopus 로고
    • Chronic myeloid leukemia and interferon-alpha: A study of complete cytogenetic responders
    • Bonifazi F, de Vivo A, Rosti G, Guilhot F, Guilhot J, Trabacchi E, et al. Chronic myeloid leukemia and interferon-alpha: a study of complete cytogenetic responders. Blood. 2001;98(10):3074-81
    • (2001) Blood , vol.98 , Issue.10 , pp. 3074-3081
    • Bonifazi, F.1    de Vivo, A.2    Rosti, G.3    Guilhot, F.4    Guilhot, J.5    Trabacchi, E.6
  • 2
    • 0029947186 scopus 로고    scopus 로고
    • Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
    • Druker BJ, Tamura S, Buchdunger E, Ohno S, Segal GM, Fanning S, et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med. 1996;2(5):561-6.
    • (1996) Nat Med , vol.2 , Issue.5 , pp. 561-566
    • Druker, B.J.1    Tamura, S.2    Buchdunger, E.3    Ohno, S.4    Segal, G.M.5    Fanning, S.6
  • 3
    • 10744233716 scopus 로고    scopus 로고
    • Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
    • O'Brien SG, Guilhot F, Larson RA, Gathmann I, Baccarani M, Cervantes F, et al. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med. 2003;348(11):994-1004.
    • (2003) N Engl J Med , vol.348 , Issue.11 , pp. 994-1004
    • O'Brien, S.G.1    Guilhot, F.2    Larson, R.A.3    Gathmann, I.4    Baccarani, M.5    Cervantes, F.6
  • 4
    • 33747154547 scopus 로고    scopus 로고
    • Evolving concepts in the management of chronic myeloid leukemia: Recommendations from an expert panel on behalf of the European LeukemiaNet
    • Baccarani M, Saglio G, Goldman J, Hochhaus A, Simonsson B, Appelbaum F, et al. Evolving concepts in the management of chronic myeloid leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet. Blood. 2006; 108(6):1809-20.
    • (2006) Blood , vol.108 , Issue.6 , pp. 1809-1820
    • Baccarani, M.1    Saglio, G.2    Goldman, J.3    Hochhaus, A.4    Simonsson, B.5    Appelbaum, F.6
  • 6
    • 0030873359 scopus 로고    scopus 로고
    • Expression of interferon regulatory factor (IRF) genes and response to interferonalpha in chronic myeloid leukaemia
    • Hochhaus A, Yan XH, Willer A, Hehlmann R, Gordon MY, Goldman JM, Melo JV. Expression of interferon regulatory factor (IRF) genes and response to interferonalpha in chronic myeloid leukaemia. Leukemia. 1997;11(7):933-9.
    • (1997) Leukemia , vol.11 , Issue.7 , pp. 933-939
    • Hochhaus, A.1    Yan, X.H.2    Willer, A.3    Hehlmann, R.4    Gordon, M.Y.5    Goldman, J.M.6    Melo, J.V.7
  • 7
    • 0025868121 scopus 로고
    • Interferon-alpha overrides the deficient adhesion of chronic myeloid leukemia primitive progenitor cells to bone marrow stromal cells
    • Dowding C, Guo AP, Osterholz J, Siczkowski M, Goldman J, Gordon M. Interferon-alpha overrides the deficient adhesion of chronic myeloid leukemia primitive progenitor cells to bone marrow stromal cells. Blood. 1991;78(2):499-505.
    • (1991) Blood , vol.78 , Issue.2 , pp. 499-505
    • Dowding, C.1    Guo, A.P.2    Osterholz, J.3    Siczkowski, M.4    Goldman, J.5    Gordon, M.6
  • 8
    • 0029888021 scopus 로고    scopus 로고
    • Interferon-alpha restores normal beta 1 integrin-mediated inhibition of hematopoietic progenitor proliferation by the marrow microenvironment in chronic myelogenous leukemia
    • Bhatia R, McCarthy JB, Verfaillie CM. Interferon-alpha restores normal beta 1 integrin-mediated inhibition of hematopoietic progenitor proliferation by the marrow microenvironment in chronic myelogenous leukemia. Blood. 1996;87(9):3883-91.
    • (1996) Blood , vol.87 , Issue.9 , pp. 3883-3891
    • Bhatia, R.1    McCarthy, J.B.2    Verfaillie, C.M.3
  • 9
    • 1642541167 scopus 로고    scopus 로고
    • IFN-alpha promotes the rapid differentiation of monocytes from patients with chronic myeloid leukemia into activated dendritic cells tuned to undergo full maturation after LPS treatment
    • Gabriele L, Borghi P, Rozera C, Sestili P, Andreotti M, Guarini A, et al. IFN-alpha promotes the rapid differentiation of monocytes from patients with chronic myeloid leukemia into activated dendritic cells tuned to undergo full maturation after LPS treatment. Blood. 2004;103(3):980-7.
    • (2004) Blood , vol.103 , Issue.3 , pp. 980-987
    • Gabriele, L.1    Borghi, P.2    Rozera, C.3    Sestili, P.4    Andreotti, M.5    Guarini, A.6
  • 10
    • 0031885797 scopus 로고    scopus 로고
    • Evidence for specific immune response against P210 BCR-ABL in long-term remission CML patients treated with interferon
    • Oka T, Sastry KJ, Nehete P, Schapiro SJ, Guo JQ, Talpaz M, Arlinghaus RB. Evidence for specific immune response against P210 BCR-ABL in long-term remission CML patients treated with interferon. Leukemia. 1998;12(2):155-63.
    • (1998) Leukemia , vol.12 , Issue.2 , pp. 155-163
    • Oka, T.1    Sastry, K.J.2    Nehete, P.3    Schapiro, S.J.4    Guo, J.Q.5    Talpaz, M.6    Arlinghaus, R.B.7
  • 11
    • 0037217978 scopus 로고    scopus 로고
    • Interferon-alpha, but not the ABL-kinase inhibitor imatinib (STI571), induces expression of myeloblastin and a specific T-cell response in chronic myeloid leukemia
    • Burchert A, Wölfl S, Schmidt M, Brendel C, Denecke B, Cai D, et al. Interferon-alpha, but not the ABL-kinase inhibitor imatinib (STI571), induces expression of myeloblastin and a specific T-cell response in chronic myeloid leukemia. Blood. 2003; 101(1):259-64.
    • (2003) Blood , vol.101 , Issue.1 , pp. 259-264
    • Burchert, A.1    Wölfl, S.2    Schmidt, M.3    Brendel, C.4    Denecke, B.5    Cai, D.6
  • 12
    • 0035383771 scopus 로고    scopus 로고
    • Expression of interferon consensus sequence binding protein induces potent immunity against BCR/ABL-induced leukemia
    • Deng M, Daley GQ. Expression of interferon consensus sequence binding protein induces potent immunity against BCR/ABL-induced leukemia. Blood. 2001; 97(11):3491-7.
    • (2001) Blood , vol.97 , Issue.11 , pp. 3491-3497
    • Deng, M.1    Daley, G.Q.2
  • 13
    • 0035383797 scopus 로고    scopus 로고
    • Expression of nuclear transcription factor interferon consensus sequence binding protein in chronic myeloid leukemia correlates with pretreatment risk features and cytogenetic response to interferon-alpha
    • Schmidt M, Hochhaus A, Nitsche A, Hehlmann R, Neubauer A. Expression of nuclear transcription factor interferon consensus sequence binding protein in chronic myeloid leukemia correlates with pretreatment risk features and cytogenetic response to interferon-alpha. Blood. 2001; 97(11):3648-50.
    • (2001) Blood , vol.97 , Issue.11 , pp. 3648-3650
    • Schmidt, M.1    Hochhaus, A.2    Nitsche, A.3    Hehlmann, R.4    Neubauer, A.5
  • 15
    • 77950396947 scopus 로고    scopus 로고
    • Significant Higher Rates of Undetectable Molecular Residual Disease and Molecular Responses with Pegylated Form of Interferon a2a in Combination with Imatinib (IM) for the Treatment of Newly Diagnosed Chronic Phase (CP) Chronic Myeloid Leukaemia (CML) Patients (pts): Confirmatory Results at 18 Months of Part 1 of the Spirit Phase III Randomized Trial of the French CML Group (FI LMC)
    • (ASH Annual Meeting Abstracts) Abstract 340
    • Guilhot F, Preudhomme C, Guilhot J, et al. Significant Higher Rates of Undetectable Molecular Residual Disease and Molecular Responses with Pegylated Form of Interferon a2a in Combination with Imatinib (IM) for the Treatment of Newly Diagnosed Chronic Phase (CP) Chronic Myeloid Leukaemia (CML) Patients (pts): Confirmatory Results at 18 Months of Part 1 of the Spirit Phase III Randomized Trial of the French CML Group (FI LMC). Blood (ASH Annual Meeting Abstracts) 114: abstract 340,2009.
    • (2009) Blood , vol.114
    • Guilhot, F.1    Preudhomme, C.2    Guilhot, J.3
  • 16
    • 10244257546 scopus 로고    scopus 로고
    • Imatinib and pegylated human recombinant interferon-alpha2b in early chronicphase chronic myeloid leukemia
    • Baccarani M, Martinelli G, Rosti G, Trabacchi E, Testoni N, Bassi S, et al. Imatinib and pegylated human recombinant interferon-alpha2b in early chronicphase chronic myeloid leukemia. Blood. 2004;104(13):4245-51.
    • (2004) Blood , vol.104 , Issue.13 , pp. 4245-4251
    • Baccarani, M.1    Martinelli, G.2    Rosti, G.3    Trabacchi, E.4    Testoni, N.5    Bassi, S.6
  • 17
    • 43449118108 scopus 로고    scopus 로고
    • Front-line treatment of Philadelphia positive chronic myeloid leukemia with imatinib and interferon-alfa: 5-year outcome
    • Palandri F, Iacobucci I, Castagnetti F, Testoni N, Poerio A, Amabile M, et al. Front-line treatment of Philadelphia positive chronic myeloid leukemia with imatinib and interferon-alfa: 5-year outcome. Haematologica. 2008;93(5):770-4.
    • (2008) Haematologica , vol.93 , Issue.5 , pp. 770-774
    • Palandri, F.1    Iacobucci, I.2    Castagnetti, F.3    Testoni, N.4    Poerio, A.5    Amabile, M.6
  • 18
    • 66549108340 scopus 로고    scopus 로고
    • Comparison of imatinib 400 mg and 800 mg daily in the front-line treatment of highrisk, Philadelphia-positive chronic myeloid leukemia: A European LeukemiaNet Study
    • Baccarani M, Rosti G, Castagnetti F, Haznedaroglu I, Porkka K, Abruzzese E, et al. Comparison of imatinib 400 mg and 800 mg daily in the front-line treatment of highrisk, Philadelphia-positive chronic myeloid leukemia: a European LeukemiaNet Study. Blood. 2009; 113(19): 4497-504.
    • (2009) Blood , vol.113 , Issue.19 , pp. 4497-4504
    • Baccarani, M.1    Rosti, G.2    Castagnetti, F.3    Haznedaroglu, I.4    Porkka, K.5    Abruzzese, E.6
  • 19
    • 77956033172 scopus 로고    scopus 로고
    • On behalf of the GINEMA Working Party on CML. Front-line treatment of Philadelphia-positive chronic myeloid leukemia patients at low Sokal risk with Imatinib 400 mg. A multicentric study of the GIMEMA CML WORKING PARTY
    • Rosti G, Palandri F, Castagnetti F, Iacobucci I, Marzocchi G, Testoni N, et al; on behalf of the GINEMA Working Party on CML. Front-line treatment of Philadelphia-positive chronic myeloid leukemia patients at low Sokal risk with Imatinib 400 mg. A multicentric study of the GIMEMA CML WORKING PARTY. Haematologica. 2007; 92 (suppl 3):3.
    • (2007) Haematologica , vol.92 , Issue.SUPPL. 3 , pp. 3
    • Rosti, G.1    Palandri, F.2    Castagnetti, F.3    Iacobucci, I.4    Marzocchi, G.5    Testoni, N.6
  • 20
    • 9144222001 scopus 로고    scopus 로고
    • Standardization and quality control studies of 'realtime' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program
    • Gabert J, Beillard E, van der Velden VH, Bi W, Grimwade D, Pallisgaard N, et al. Standardization and quality control studies of 'realtime' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program. Leukemia. 2003;17(12):2318-57.
    • (2003) Leukemia , vol.17 , Issue.12 , pp. 2318-2357
    • Gabert, J.1    Beillard, E.2    der Velden, V.V.H.3    Bi, W.4    Grimwade, D.5    Pallisgaard, N.6
  • 21
    • 33745603988 scopus 로고    scopus 로고
    • Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: Review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results
    • Hughes T, Deininger M, Hochhaus A, Branford S, Radich J, Kaeda J, et al. Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results. Blood. 2006;108(1):28-37.
    • (2006) Blood , vol.108 , Issue.1 , pp. 28-37
    • Hughes, T.1    Deininger, M.2    Hochhaus, A.3    Branford, S.4    Radich, J.5    Kaeda, J.6
  • 22
    • 77949704880 scopus 로고    scopus 로고
    • Discontinuation of imatinib therapy after achieving a molecular response in chronic myeloid leukemia patients
    • (ASH Annual Meeting Abstracts) Abstract 859
    • Mahon F-X, Rea D, Guilhot F, et al. Discontinuation of imatinib therapy after achieving a molecular response in chronic myeloid leukemia patients. Blood (ASH Annual Meeting Abstracts) 114:abstract 859,2009.
    • (2009) Blood , vol.114
    • Mahon, F.-X.1    Rea, D.2    Guilhot, F.3
  • 23
    • 75749105885 scopus 로고    scopus 로고
    • Phase III, randomized, open-label study of daily imatinib mesylate 400 mg versus 800 mg in patients with newly diagnosed, previously untreated chronic myeloid leukemia in chronic phase using molecular end points: Tyrosine kinase inhibitor optimization and selectivity study
    • Cortes JE, Baccarani M, Guilhot F, Druker BJ, Branford S, Kim DW, et al. Phase III, randomized, open-label study of daily imatinib mesylate 400 mg versus 800 mg in patients with newly diagnosed, previously untreated chronic myeloid leukemia in chronic phase using molecular end points: tyrosine kinase inhibitor optimization and selectivity study. J Clin Oncol. 2010;28(3): 424-30.
    • (2010) J Clin Oncol , vol.28 , Issue.3 , pp. 424-430
    • Cortes, J.E.1    Baccarani, M.2    Guilhot, F.3    Druker, B.J.4    Branford, S.5    Kim, D.W.6
  • 24
    • 58149160055 scopus 로고    scopus 로고
    • Australasian Leukaemia and Lymphoma Group. Impact of early dose intensity on cytogenetic and molecular responses in chronic-phase CML patients receiving 600 mg/day of imatinib as initial therapy
    • Hughes TP, Branford S, White DL, Reynolds J, Koelmeyer R, Seymour JF, et al; Australasian Leukaemia and Lymphoma Group. Impact of early dose intensity on cytogenetic and molecular responses in chronic-phase CML patients receiving 600 mg/day of imatinib as initial therapy. Blood. 2008;112(10):3965-73.
    • (2008) Blood , vol.112 , Issue.10 , pp. 3965-3973
    • Hughes, T.P.1    Branford, S.2    White, D.L.3    Reynolds, J.4    Koelmeyer, R.5    Seymour, J.F.6
  • 25
    • 75749090051 scopus 로고    scopus 로고
    • Nilotinib as front-line treatment for patients with chronic myeloid leukemia in early chronic phase
    • Cortes JE, Jones D, O'Brien S, Jabbour E, Konopleva M, Ferrajoli A, et al. Nilotinib as front-line treatment for patients with chronic myeloid leukemia in early chronic phase. J Clin Oncol. 2010;28(3):392-7
    • (2010) J Clin Oncol , vol.28 , Issue.3 , pp. 392-397
    • Cortes, J.E.1    Jones, D.2    O'Brien, S.3    Jabbour, E.4    Konopleva, M.5    Ferrajoli, A.6
  • 26
    • 73949145209 scopus 로고    scopus 로고
    • Nilotinib for the frontline treatment of Ph+ chronic myeloid leukemia
    • Rosti G, Palandri F, Castagnetti F, Breccia M, Levato L, Gugliotta G, et al. Nilotinib for the frontline treatment of Ph+ chronic myeloid leukemia. Blood. 2009;114(24): 4933-8.
    • (2009) Blood , vol.114 , Issue.24 , pp. 4933-4938
    • Rosti, G.1    Palandri, F.2    Castagnetti, F.3    Breccia, M.4    Levato, L.5    Gugliotta, G.6
  • 27
    • 75749129911 scopus 로고    scopus 로고
    • Results of dasatinib therapy in patients with early chronic-phase chronic myeloid leukemia
    • Cortes JE, Jones D, O'Brien S, Jabbour E, Ravandi F, Koller C, et al. Results of dasatinib therapy in patients with early chronic-phase chronic myeloid leukemia. J Clin Oncol. 2010;28(3):398-404.
    • (2010) J Clin Oncol , vol.28 , Issue.3 , pp. 398-404
    • Cortes, J.E.1    Jones, D.2    O'Brien, S.3    Jabbour, E.4    Ravandi, F.5    Koller, C.6


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