Single maintenance and reliever therapy (SMART) of asthma: A critical appraisal

Thorax

Volumn 65, Issue 8, 2010, Pages 747-752

  Chapman, Kenneth R ^a   Barnes, Neil C ^b   Greening, Andrew P ^c   Jones, Paul W ^d   Pedersen, S ^e  

^a TORONTO WESTERN HOSPITAL   (Canada)

^b LONDON CHEST HOSPITAL   (United Kingdom)

^c WESTERN GENERAL HOSPITAL   (United Kingdom)

^d ST GEORGE S HOSPITAL   (United Kingdom)

^e KOLDING HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BUDESONIDE; BUDESONIDE PLUS FORMOTEROL; CORTICOSTEROID; FLUTICASONE PROPIONATE PLUS SALMETEROL; FORMOTEROL; TERBUTALINE;

ASTHMA; CLINICAL RESEARCH; CLINICAL TRIAL; COMPARATIVE STUDY; DISEASE EXACERBATION; HUMAN; MAINTENANCE THERAPY; MONOTHERAPY; PATIENT MONITORING; PRIORITY JOURNAL; REVIEW; SINGLE MAINTENANCE AND RELIEVER THERAPY; TREATMENT OUTCOME;

EID: 77956026534     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thx.2009.128504     Document Type: Review

References (38)

1. Global Initiative for Asthma (GINA). Global strategy for asthma management and prevention. http://www.ginasthma.com (accessed 9 Dec 2008).
2. Greening AP, Ind PW, Northfield M, et al. Added salmeterol versus higher-dose corticosteroid in asthma patients with symptoms on existing inhaled corticosteroid. Lancet 1994;344:219-24. (Pubitemid 24229008)
3. Pauwels RA, Lofdahl CG, Postma DS, et al; Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group. Effect of inhaled formoterol and budesonide on exacerbations of asthma. N Engl J Med 1997;337:1405-11.
4. Bateman ED, Boushey HA, Bousquet J, et al. Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma Control study. Am J Respir Crit Care Med 2004;170:836-44.
5. Selroos O. A smarter way to manage asthma with a combination of a long-acting beta(2)-agonist and inhaled corticosteroid. Ther Clin Risk Manag 2007;3:349-59.
6. Barnes PJ. Using a combination inhaler (budesonide plus formoterol) as rescue therapy improves asthma control. BMJ 2007;335:513.
7. Humbert M, Andersson TL, Buhl R. Budesonide/formoterol for maintenance and reliever therapy in the management of moderate to severe asthma. Allergy 2008;63:1567-80.
8. Cates CJ, Lasserson TJ. Combination formoterol and budesonide as maintenance and reliever therapy versus inhaled steroid maintenance for chronic asthma in adults and children. Cochrane Database Syst Rev 2009;(2):CD007313.
9. Pavord ID, Jeffery PK, Qiu Y, et al. Airway inflammation in patients with asthma with high-fixed or low-fixed plus as-needed budesonide/formoterol. J Allergy Clin Immunol 2009;123:1083-9.
10. Rabe KF, Pizzichini E, Stallberg B, et al. Budesonide/formoterol in a single inhaler for maintenance and relief in mild-to-moderate asthma: a randomized, double-blind trial. Chest 2006;129:246-56.
11. Scicchitano R, Aalbers R, Ukena D, et al. Efficacy and safety of budesonide/formoterol single inhaler therapy versus a higher dose of budesonide in moderate to severe asthma. Curr Med Res Opin 2004;20:1403-18.
12. O'Byrne PM, Bisgaard H, Godard PP, et al. Budesonide/formoterol combination therapy as both maintenance and reliever medication in asthma. Am J Respir Crit Care Med 2005;171:129-36.
13. Reddel HK, Taylor DR, Bateman ED, et al. An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. Am J Respir Crit Care Med 2009;180:59-99.
14. Rabe KF, Atienza T, Magyar P, et al. Effect of budesonide in combination with formoterol for reliever therapy in asthma exacerbations: a randomised controlled, double-blind study. Lancet 2006;368:744-53. (Pubitemid 44279053)
15. Vogelmeier C, D'Urzo A, Pauwels R, et al. Budesonide/formoterol maintenance and reliever therapy: an effective asthma treatment option? Eur Respir J 2005;26:819-28.
16. Sears MR, Boulet LP, Laviolette M, et al. Budesonide/formoterol maintenance and reliever therapy: impact on airway inflammation in asthma. Eur Respir J 2008;31:982-9.
17. Anon. Clinical Study Report Synopsis [D5890L00008]: A comparison of the efficacy of Symbicort SMART (Symbicort)Turbuhaler 160/4.5 μg 1 inhalation b.i.d. plus as-needed) and conventional best standard treatment for the treatment of persistent asthma in adolescents and adults. A randomized, open, parallel-group, multicentre, 26 weeks study. http://www. astrazenecaclinicaltrials.com (accessed 9 Dec 2008).
18. Louis R, Joos G, Michils A, et al. A comparison of budesonide/formoterol maintenance and reliever therapy vs. conventional best practice in asthma management. Int J Clin Pract 2009;63:1479-88.
19. Bousquet J, Boulet LP, Peters MJ, et al. Budesonide/formoterol for maintenance and relief in uncontrolled asthma vs. high-dose salmeterol/ fluticasone. Respir Med 2007;101:243746.
20. Tattersfield AE, Lofdahl CG, Postma DS, et al. Comparison of formoterol and terbutaline for as-needed treatment of asthma: a randomised trial. Lancet 2001;357:257-61.
21. Kraan J, Koeter GH, vd Mark TW, et al. Changes in bronchial hyperreactivity induced by 4 weeks of treatment with antiasthmatic drugs in patients with allergic asthma: a comparison between budesonide and terbutaline. J Allergy Clin Immunol 1985;76:628-36.
22. Aldridge RE, Hancox RJ, Taylor DR, et al. Effects of terbutaline and budesonide on sputum cells and bronchial hyperresponsiveness in asthma. Am J Respir Crit Care Med 2000;161:1459-64.
23. Kuna P, Peters MJ, Manjra AI, et al. Effect of budesonide/formoterol maintenance and reliever therapy on asthma exacerbations. Int J Clin Pract 2007;61:725-36.
24. Juniper EF, O'Byrne PM, Guyatt GH, et al. Development and validation of a questionnaire to measure asthma control. Eur Respir J 1999;14:902-7.
25. Nathan RA, Sorkness CA, Kosinski M, et al. Development of the asthma control test: a survey for assessing asthma control. J Allergy Clin Immunol 2004;113:59-65. (Pubitemid 38096162)
26. Bateman ED, Clark TJH, Frith L, et al. Rate of response of individual control measures varies and may overestimate asthma control: an analysis of the GOAL study. J Asthma 2007;44:667-73.
27. Bateman ED, Reddel HK, Eriksson G, et al. Overall asthma control: the relationship between current control and future risk. J Allergy Clin Immunol 2010;125:600-8.
28. Lloyd A, Price D, Brown R. The impact of asthma exacerbations on health-related quality of life in moderate to severe asthma patients in the UK. Prim Care Respir J 2007;16:22-7.
29. Lloyd A, McIntosh E, Rabe KF, et al. Patient preferences for asthma therapy: a discrete choice experiment. Prim Care Respir J 2007;16:241-8. (Pubitemid 47281450)
30. Barnes PJ. Scientific rationale for using a single inhaler for asthma control. Eur Respir J 2007;29:587-95.
31. Simmons MS, Nides MA, Rand CS, et al. Unpredictability of deception in compliance with physician-prescribed bronchodilator inhaler use in a clinical trial. Chest 2000;118:290-5.
32. Simmons MS, Nides MA, Rand CS, et al. Trends in compliance with bronchodilator inhaler use between follow-up visits in a clinical trial. Chest 1996;109:963-8.
33. Chapman KR. Reality-based medicine. Chest 2000;118:281-3.
34. Bosley CM, Parry DT, Cochrane GM. Patient compliance with inhaled medication: does combining beta-agonists with corticosteroids improve compliance? Eur Respir J 1994;7:504-9.
35. Rubinfeld AR, Pain MC. Perception of asthma. Lancet 1976;1:882-4.
36. Rushford N, Tiller JW, Pain MC. Perception of natural fluctuations in peak flow in asthma: clinical severity and psychological correlates. J Asthma 1998;35:251-9.
37. Burdon JG, Juniper EF, Killian KJ, et al. The perception of breathlessness in asthma. Am Rev Respir Dis 1982;126:825-8.
38. Mawhinney H, Spector SL, Heitjan D, et al. As-needed medication use in asthma usage patterns and patient characteristics. J Asthma 1993;30:61-71.