Effect of long-term steroid withdrawal in renal transplant recipients: A retrospective cohort study

NDT Plus

Volumn 3, Issue SUPPLL. 2, 2010, Pages

  Gonzalez Molina, Miguel ^a   Gentil, Miguel Angel ^b   Burgos, Dolores ^a   Cabello, Mercedes ^a   Cobelo, Carmen ^a   Bustamante, Jesús ^c   Errasti, Pedro ^d   Franco, Antonio ^e   Hernández, Domingo ^a  

^a HOSPITAL REGIONAL UNIVERSITARIO DE MÁLAGA   (Spain)

^b HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^c HOSPITAL CLÍNICO UNIVERSITARIO DE VALLADOLID   (Spain)

^d UNIVERSITY CLINIC OF NAVARRA   (Spain)

^e HOSPITAL GENERAL UNIVERSITARIO DE ALICANTE   (Spain)

Author keywords

graft; patient survival; steroid withdrawal

Indexed keywords

ANTIHYPERTENSIVE AGENT; AZATHIOPRINE; CHOLESTEROL; CYCLOSPORIN; INSULIN; LYMPHOCYTE ANTIBODY; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; ORAL ANTIDIABETIC AGENT; RAPAMYCIN; STEROID; TACROLIMUS; TRIACYLGLYCEROL;

ACUTE GRAFT REJECTION; ARTICLE; BLOOD PRESSURE; COHORT ANALYSIS; DIABETES MELLITUS; DRUG EFFECT; DRUG WITHDRAWAL; GRAFT RECIPIENT; GRAFT SURVIVAL; HUMAN; KIDNEY FUNCTION; KIDNEY GRAFT; ORGAN DONOR; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK FACTOR; SCORING SYSTEM;

EID: 77956021846     PISSN: 17530784     EISSN: 17530792     Source Type: Journal    
DOI: 10.1093/ndtplus/sfq064     Document Type: Article

References (20)

1. Augustine JJ, Hricik DE. Steroid sparing in kidney transplantation: changing paradigms, improving outcomes, and remaining questions. Clin J Am Soc Nephrol 2006; 1: 1080-1089
2. Stratta RJ, Armbrust MJ, Oh CS et al. Withdrawal of steroid inmunosuppression in renal transplant recipients. Transplantation 1988; 45: 323-328
3. Hricik DE, Whalen CC, Lautman J et al. Withdrawal of steroids after renal transplantation-clinical predictors of outcome. Transplantation 1992; 53: 41-45
4. Sinclair NR. Low-dose steroid therapy in cyclosporine-treated renal transplant recipients with well-functioning grafts. CMAJ 1992; 147: 645-657
5. European Best Practice Guidelines for Renal Transplantation. Section IV: long-term management of the transplant recipient. IV.3.1 Longterm immunosuppression. Late steroid or cyclosporine withdrawal. Nephrol Dial Transplant 2002; 17: 19-20
6. Grinyo JM, Gil-Vernet S, Serron D et al. Steroid withdrawal in mycophenolate mofetil-treated renal allograft recipients. Transplantation 1997; 63: 1688-1690
7. Ter Muelen CG, van Riemsdijk I, Hene RJ et al. Steroid-withdrawal at 3 days after renal transplantation with anti-IL-2 receptor alpha therapy: a prospective, randomized, multicenter study. Am J Transplant 2004; 4: 803-810
8. Sola E, Alferez MJ, Cabello M et al. Low-dose and rapid steroid withdrawal in renal transplant patients treated with tacrolimus and mycophenolate mofetil. Transplant Proc 2002; 34: 1689-1690
9. Levy AS, Bosch JP, Lewis JP et al. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new predictor equation. Modification of diet in Renal Disease Study Group. Ann Intern Med 1999; 130: 461-470
10. Heinze G, Mitterbauer C, Regele H et al. Angiotensin-converting enzyme inhibitor or angiotensin II type 1 receptor antagonist therapy is associated with prolonged patient and graft survival after renal transplantation. J Am Soc Nephrol 2006; 17: 889-899
11. Kasiske BL, Chakkera HA, Louis TA et al. A meta-analysis of immunosuppression withdrawal trials in renal transplantation. J Am Soc Nephrol 2000; 11: 1910-1917
12. Pascual J, Quereda C, Zamora J et al. Steroid withdrawal in renal transplant patients on triple therapy with calcineurin inhibitor and mycophenolate mofetil: a meta-analysis of randomized, controlled trials. Transplantation 2004; 78: 1548-1556
13. Maiorca R, Cristinelli L, Brunori G et al. Prospective controlled trial of steroid withdrawal after six months in renal transplant recipients treated with cyclosporine. Transplant Proc 1988; 20: 121-123
14. Schulak JA, Mayers JT, Moritz CE et al. A prospective, randomized trial of prednisone versus no prednisone maintenance therapy in cyclosporine-treated and azathioprine-treated renal transplant patients. Transplantation 1990; 49: 327-332
15. Hricik DE, O'Tool M, Schulak JA et al. Steroid-free immunosuppression in cyclosporine-treated renal transplant recipients: a meta-analysis. J Am Soc Nephrol 1993; 4: 1300-1305
16. Wlodarzyk Z, Waleszewsky J, Perenr F et al. Freedom from rejection and stable kidney function are excellent criteria for steroid withdrawal in TAC-treated kidney transplant recipients. Ann Transplant 2002; 76: 28-31
17. Woodle ES, Vincenti F, Lorber MI et al. A multicenter pilot study of early (4-day) steroid cessation in renal transplant recipients under simulect, tacrolimus and sirolimus. Am J Transplant 2005; 5: 157-166
18. Opelz G, Döler B, Laux G. For the collaborative transplant study-Long-term prospective study of steroid withdrawal in kidney and heart transplant recipients. Am J Transplant 2005; 5: 720-728
19. Ojo AO, Hanson JA,Wolfe RA et al. Long-term survival in renal transplant recipients with graft function. Kidney Int 2000; 57: 307-313
20. Hricik DE, Bartucci MR, Meyes JT et al. The effects of steroid withdrawal on the lipoprotein profiles of cyclosporine-treated kidney and kidney-pancreas recipients. Transplantation 1992; 54: 868-871