메뉴 건너뛰기




Volumn 19, Issue 6, 2010, Pages 356-364

Efficacy and mechanisms of intraocular pressure reduction with latanoprost and timolol in participants with ocular hypertension: A comparison of 1 and 6 weeks of treatment

Author keywords

aqueous flow; aqueous humor dynamics; intraocular pressure; latanoprost; outflow facility; timolol

Indexed keywords

LATANOPROST; TIMOLOL; ANTIHYPERTENSIVE AGENT; PROSTAGLANDIN F;

EID: 77956016049     PISSN: 10570829     EISSN: None     Source Type: Journal    
DOI: 10.1097/IJG.0b013e3181d12dd8     Document Type: Article
Times cited : (13)

References (48)
  • 1
    • 0036284225 scopus 로고    scopus 로고
    • Aqueous humor dynamics in ocular hypertensive patients
    • Toris CB, Koepsell SA, Yablonski ME, et al. Aqueous humor dynamics in ocular hypertensive patients. J Glaucoma. 2002; 11:253-258.
    • (2002) J Glaucoma , vol.11 , pp. 253-258
    • Toris, C.B.1    Koepsell, S.A.2    Yablonski, M.E.3
  • 2
    • 33644655886 scopus 로고    scopus 로고
    • The number of people with glaucoma worldwide in 2010 and 2020
    • Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol. 2006; 90:262-267.
    • (2006) Br J Ophthalmol , vol.90 , pp. 262-267
    • Quigley, H.A.1    Broman, A.T.2
  • 3
    • 0030023938 scopus 로고    scopus 로고
    • Comparison of latanoprost and timolol in patients with ocular hypertension and glaucoma: A six-month masked, multicenter trial in the United States. The United States Latanoprost Study Group
    • Camras CB. Comparison of latanoprost and timolol in patients with ocular hypertension and glaucoma: a six-month masked, multicenter trial in the United States. The United States Latanoprost Study Group. Ophthalmology. 1996;103:138-147.
    • (1996) Ophthalmology , vol.103 , pp. 138-147
    • Camras, C.B.1
  • 4
    • 0033497559 scopus 로고    scopus 로고
    • A 12- month, randomized, double-masked study comparing latanoprost with timolol in pigmentary glaucoma
    • Mastropasqua L, Carpineto P, Ciancaglini M, et al. A 12- month, randomized, double-masked study comparing latanoprost with timolol in pigmentary glaucoma. Ophthalmology. 1999;106:550-555.
    • (1999) Ophthalmology , vol.106 , pp. 550-555
    • Mastropasqua, L.1    Carpineto, P.2    Ciancaglini, M.3
  • 5
    • 0033917235 scopus 로고    scopus 로고
    • A pooled-data analysis of three randomized, double-masked, six-month clinical studies comparing the intraocular pressure reducing effect of latanoprost and timolol
    • Hedman K, Alm A. A pooled-data analysis of three randomized, double-masked, six-month clinical studies comparing the intraocular pressure reducing effect of latanoprost and timolol. Eur J Ophthalmol. 2000;10:95-104.
    • (2000) Eur J Ophthalmol , vol.10 , pp. 95-104
    • Hedman, K.1    Alm, A.2
  • 6
    • 0345599882 scopus 로고    scopus 로고
    • Pooled-data analysis of three randomized, double-masked, six-month studies comparing intraocular pressure-reducing effects of latanoprost and timolol in patients with ocular hypertension
    • Hedman K, Alm A, Gross RL. Pooled-data analysis of three randomized, double-masked, six-month studies comparing intraocular pressure-reducing effects of latanoprost and timolol in patients with ocular hypertension. J Glaucoma. 2003;12: 463-465.
    • (2003) J Glaucoma , vol.12 , pp. 463-465
    • Hedman, K.1    Alm, A.2    Gross, R.L.3
  • 7
    • 67650432141 scopus 로고    scopus 로고
    • Assessing the efficacy of latanoprost vs timolol using an alternate efficacy parameter: The intervisit intraocular pressure range
    • Varma R, Hwang LJ, Grunden JW, et al. Assessing the efficacy of latanoprost vs timolol using an alternate efficacy parameter: the intervisit intraocular pressure range. Am J Ophthalmol. 2009;148:221-226.
    • (2009) Am J Ophthalmol , vol.148 , pp. 221-226
    • Varma, R.1    Hwang, L.J.2    Grunden, J.W.3
  • 8
    • 0344305395 scopus 로고    scopus 로고
    • Rate of response to latanoprost or timolol in patients with ocular hypertension or glaucoma
    • Camras CB, Hedman K. Rate of response to latanoprost or timolol in patients with ocular hypertension or glaucoma. J Glaucoma. 2003;12:466-469.
    • (2003) J Glaucoma , vol.12 , pp. 466-469
    • Camras, C.B.1    Hedman, K.2
  • 9
    • 0018082448 scopus 로고
    • A fluorophotometric study of the effect of topical timolol on aqueous humor dynamics
    • Yablonski ME, Zimmerman TJ, Waltman SR, et al. A fluorophotometric study of the effect of topical timolol on aqueous humor dynamics. Exp Eye Res. 1978;27:135-142.
    • (1978) Exp Eye Res , vol.27 , pp. 135-142
    • Yablonski, M.E.1    Zimmerman, T.J.2    Waltman, S.R.3
  • 10
    • 0031453576 scopus 로고    scopus 로고
    • Comparison of dorzolamide and timolol as suppressors of aqueous humor flow in humans
    • Wayman L, Larsson LI, Maus T, et al. Comparison of dorzolamide and timolol as suppressors of aqueous humor flow in humans. Arch Ophthalmol. 1997;115:1368-1371.
    • (1997) Arch Ophthalmol , vol.115 , pp. 1368-1371
    • Wayman, L.1    Larsson, L.I.2    Maus, T.3
  • 11
    • 0035066403 scopus 로고    scopus 로고
    • Aqueous humor flow in normal human eyes treated with brimonidine and timolol, alone and in combination
    • Larsson LI. Aqueous humor flow in normal human eyes treated with brimonidine and timolol, alone and in combination. Arch Ophthalmol. 2001;119:492-495.
    • (2001) Arch Ophthalmol , vol.119 , pp. 492-495
    • Larsson, L.I.1
  • 12
    • 0020067083 scopus 로고
    • The effects of timolol maleate and acetazolamide on the rate of aqueous formation in normal human subjects
    • Dailey RA, Brubaker RF, Bourne WM. The effects of timolol maleate and acetazolamide on the rate of aqueous formation in normal human subjects. Am J Ophthalmol. 1982;93:232-237.
    • (1982) Am J Ophthalmol , vol.93 , pp. 232-237
    • Dailey, R.A.1    Brubaker, R.F.2    Bourne, W.M.3
  • 13
    • 0027379360 scopus 로고
    • The effects on aqueous dynamics of PhXA41, a new prostaglandin F2 alpha analogue, after topical application in normal and ocular hypertensive human eyes
    • Ziai N, Dolan JW, Kacere RD, et al. The effects on aqueous dynamics of PhXA41, a new prostaglandin F2 alpha analogue, after topical application in normal and ocular hypertensive human eyes. Arch Ophthalmol. 1993;111:1351-1358.
    • (1993) Arch Ophthalmol , vol.111 , pp. 1351-1358
    • Ziai, N.1    Dolan, J.W.2    Kacere, R.D.3
  • 14
    • 0027216487 scopus 로고
    • Effects of PhXA41, a new prostaglandin F2 alpha analog, on aqueous humor dynamics in human eyes
    • Toris CB, Camras CB, Yablonski ME. Effects of PhXA41, a new prostaglandin F2 alpha analog, on aqueous humor dynamics in human eyes. Ophthalmology. 1993;100:1297-1304.
    • (1993) Ophthalmology , vol.100 , pp. 1297-1304
    • Toris, C.B.1    Camras, C.B.2    Yablonski, M.E.3
  • 15
    • 56649118924 scopus 로고    scopus 로고
    • A review of additivity to prostaglandin analogs: Fixed and unfixed combinations
    • Tabet R, Stewart WC, Feldman R, et al. A review of additivity to prostaglandin analogs: fixed and unfixed combinations. Surv Ophthalmol. 2008;53 (Suppl 1):S85-S92.
    • (2008) Surv Ophthalmol , vol.53 , Issue.SUPPL. 1
    • Tabet, R.1    Stewart, W.C.2    Feldman, R.3
  • 16
    • 42649122971 scopus 로고    scopus 로고
    • Mechanism of action of bimatoprost, latanoprost, and travoprost in healthy subjects. A crossover study
    • Lim KS, Nau CB, O'Byrne MM, et al. Mechanism of action of bimatoprost, latanoprost, and travoprost in healthy subjects. A crossover study. Ophthalmology. 2008;115:790-795.
    • (2008) Ophthalmology , vol.115 , pp. 790-795
    • Lim, K.S.1    Nau, C.B.2    O'Byrne, M.M.3
  • 17
    • 0028973225 scopus 로고
    • Prostaglandin F2 alpha effects on isolated rhesus monkey ciliary muscle
    • Poyer JF, Millar C, Kaufman PL. Prostaglandin F2 alpha effects on isolated rhesus monkey ciliary muscle. Invest Ophthalmol Vis Sci. 1995;36:2461-2465.
    • (1995) Invest Ophthalmol Vis Sci , vol.36 , pp. 2461-2465
    • Poyer, J.F.1    Millar, C.2    Kaufman, P.L.3
  • 18
    • 0017366741 scopus 로고
    • The effect of prostaglandins on the isolated internal muscles of the mammalian eye, including man
    • Alphen GW, Wilhelm PB, Elsenfeld PW. The effect of prostaglandins on the isolated internal muscles of the mammalian eye, including man. Doc Ophthalmol. 1977;42:397-415.
    • (1977) Doc Ophthalmol , vol.42 , pp. 397-415
    • Alphen, G.W.1    Wilhelm, P.B.2    Elsenfeld, P.W.3
  • 19
    • 0032144288 scopus 로고    scopus 로고
    • Effect of latanoprost on the extracellular matrix of the ciliary muscle. A study on cultured cells and tissue sections
    • Ocklind A. Effect of latanoprost on the extracellular matrix of the ciliary muscle. A study on cultured cells and tissue sections. Exp Eye Res. 1998;67:179-191.
    • (1998) Exp Eye Res , vol.67 , pp. 179-191
    • Ocklind, A.1
  • 20
    • 0032588080 scopus 로고    scopus 로고
    • Topical prostaglandin F2alpha treatment reduces collagen types i III and IV in the monkey uveoscleral outflow pathway
    • Sagara T, Gaton DD, Lindsey JD, et al. Topical prostaglandin F2alpha treatment reduces collagen types I, III, and IV in the monkey uveoscleral outflow pathway. Arch Ophthalmol. 1999; 117:794-801.
    • (1999) Arch Ophthalmol , vol.117 , pp. 794-801
    • Sagara, T.1    Gaton, D.D.2    Lindsey, J.D.3
  • 21
    • 0034910110 scopus 로고    scopus 로고
    • Increased matrix metalloproteinases 1, 2, and 3 in the monkey uveoscleral outflow pathway after topical prostaglandin F(2 alpha)-isopropyl ester treatment
    • Gaton DD, Sagara T, Lindsey JD, et al. Increased matrix metalloproteinases 1, 2, and 3 in the monkey uveoscleral outflow pathway after topical prostaglandin F(2 alpha)-isopropyl ester treatment. Arch Ophthalmol. 2001;119:1165-1170.
    • (2001) Arch Ophthalmol , vol.119 , pp. 1165-1170
    • Gaton, D.D.1    Sagara, T.2    Lindsey, J.D.3
  • 22
    • 0036905886 scopus 로고    scopus 로고
    • Latanoprost's effects on TIMP-1 and TIMP-2 expression in human ciliary muscle cells
    • Anthony TL, Lindsey JD, Weinreb RN. Latanoprost's effects on TIMP-1 and TIMP-2 expression in human ciliary muscle cells. Invest Ophthalmol Vis Sci. 2002;43:3705-3711.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 3705-3711
    • Anthony, T.L.1    Lindsey, J.D.2    Weinreb, R.N.3
  • 23
    • 0036191197 scopus 로고    scopus 로고
    • Metalloproteinase gene transcription in human ciliary muscle cells with latanoprost
    • Weinreb RN, Lindsey JD. Metalloproteinase gene transcription in human ciliary muscle cells with latanoprost. Invest Ophthalmol Vis Sci. 2002;43:716-722.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 716-722
    • Weinreb, R.N.1    Lindsey, J.D.2
  • 24
    • 9444265394 scopus 로고    scopus 로고
    • Prostaglandin FP agonists alter metalloproteinase gene expression in sclera
    • Weinreb RN, Lindsey JD, Marchenko G, et al. Prostaglandin FP agonists alter metalloproteinase gene expression in sclera. Invest Ophthalmol Vis Sci. 2004;45:4368-4377.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 4368-4377
    • Weinreb, R.N.1    Lindsey, J.D.2    Marchenko, G.3
  • 25
    • 0031441685 scopus 로고    scopus 로고
    • Prostaglandins increase matrix metalloproteinase release from human ciliary smooth muscle cells
    • Weinreb RN, Kashiwagi K, Kashiwagi F, et al. Prostaglandins increase matrix metalloproteinase release from human ciliary smooth muscle cells. Invest Ophthalmol Vis Sci. 1997;38: 2772-2780.
    • (1997) Invest Ophthalmol Vis Sci , vol.38 , pp. 2772-2780
    • Weinreb, R.N.1    Kashiwagi, K.2    Kashiwagi, F.3
  • 26
    • 56449090612 scopus 로고    scopus 로고
    • Update on the mechanism of action of topical prostaglandins for intraocular pressure reduction
    • Toris CB, Gabelt BT, Kaufman PL. Update on the mechanism of action of topical prostaglandins for intraocular pressure reduction. Survey Ophthalmology. 2008;53 (Suppl 1):S107-120.
    • (2008) Survey Ophthalmology , vol.53 , Issue.SUPPL. 1
    • Toris, C.B.1    Gabelt, B.T.2    Kaufman, P.L.3
  • 27
    • 0019365907 scopus 로고
    • Long-term drift and continued efficacy after multiyear timolol therapy
    • Steinert RF, Thomas JV, Boger WP, III. Long-term drift and continued efficacy after multiyear timolol therapy. Arch Ophthalmol. 1981;99:100-103.
    • (1981) Arch Ophthalmol , vol.99 , pp. 100-103
    • Steinert, R.F.1    Thomas, J.V.2    Boger III, W.P.3
  • 28
    • 0020065959 scopus 로고
    • Effect of chronically administered timolol on aqueous humor flow in patients with glaucoma
    • Brubaker RF, Nagataki S, Bourne WM. Effect of chronically administered timolol on aqueous humor flow in patients with glaucoma. Ophthalmology. 1982;89:280-283.
    • (1982) Ophthalmology , vol.89 , pp. 280-283
    • Brubaker, R.F.1    Nagataki, S.2    Bourne, W.M.3
  • 29
    • 0034754932 scopus 로고    scopus 로고
    • Lack of long-term drift in timolol's effectiveness in patients with ocular hypertension
    • Bengtsson B, Heijl A. Lack of long-term drift in timolol's effectiveness in patients with ocular hypertension. Invest Ophthalmol Vis Sci. 2001;42:2839-2842.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 2839-2842
    • Bengtsson, B.1    Heijl, A.2
  • 31
    • 0019445529 scopus 로고
    • Fluorophotometric study of epinephrine and timolol in human subjects
    • Schenker HI, Yablonski ME, Podos SM, et al. Fluorophotometric study of epinephrine and timolol in human subjects. Arch Ophthalmol. 1981;99:1212-1216.
    • (1981) Arch Ophthalmol , vol.99 , pp. 1212-1216
    • Schenker, H.I.1    Yablonski, M.E.2    Podos, S.M.3
  • 32
    • 0001860583 scopus 로고
    • Methods for assessing the effects of pharmacologic agents on aqueous humor dynamics
    • Tasman W, Jaeger EA, eds. Philadelphia: Lippincott
    • Hayashi M, Yablonski ME, Mindel JS. Methods for assessing the effects of pharmacologic agents on aqueous humor dynamics. In: Tasman W, Jaeger EA, eds. Duane's foundations of clinical ophthalmology. Philadelphia: Lippincott; 1993:1-9.
    • (1993) Duane's Foundations of Clinical Ophthalmology , pp. 1-9
    • Hayashi, M.1    Yablonski, M.E.2    Mindel, J.S.3
  • 33
    • 0021873537 scopus 로고
    • A fluorophotometric study of the effect of argon laser trabeculoplasty on aqueous humor dynamics
    • Yablonski ME, Cook DJ, Gray J. A fluorophotometric study of the effect of argon laser trabeculoplasty on aqueous humor dynamics. Am J Ophthalmol. 1985;99:579-582.
    • (1985) Am J Ophthalmol , vol.99 , pp. 579-582
    • Yablonski, M.E.1    Cook, D.J.2    Gray, J.3
  • 34
    • 0024403949 scopus 로고
    • Trabecular outflow facility determined by fluorophotometry in human subjects
    • Hayashi M, Yablonski ME, Novack GD. Trabecular outflow facility determined by fluorophotometry in human subjects. Exp Eye Res. 1989;48:621-625.
    • (1989) Exp Eye Res , vol.48 , pp. 621-625
    • Hayashi, M.1    Yablonski, M.E.2    Novack, G.D.3
  • 35
    • 34247644962 scopus 로고    scopus 로고
    • Effects of travoprost on aqueous humor dynamics in patients with elevated intraocular pressure
    • Toris CB, Zhan G, Fan S, et al. Effects of travoprost on aqueous humor dynamics in patients with elevated intraocular pressure. J Glaucoma. 2007;16:189-195.
    • (2007) J Glaucoma , vol.16 , pp. 189-195
    • Toris, C.B.1    Zhan, G.2    Fan, S.3
  • 36
    • 0031775011 scopus 로고    scopus 로고
    • Additive effect of dorzolamide on aqueous humor flow in patients receiving longterm treatment with timolol
    • Wayman LL, Larsson LI, Maus TL, et al. Additive effect of dorzolamide on aqueous humor flow in patients receiving longterm treatment with timolol. Arch Ophthalmol. 1998;116: 1438-1440.
    • (1998) Arch Ophthalmol , vol.116 , pp. 1438-1440
    • Wayman, L.L.1    Larsson, L.I.2    Maus, T.L.3
  • 37
    • 33845604091 scopus 로고    scopus 로고
    • Topical dorzolamide 2%/timolol 0.5% ophthalmic solution: A review of its use in the treatment of glaucoma and ocular hypertension
    • Frampton JE, Perry CM. Topical dorzolamide 2%/timolol 0.5% ophthalmic solution: a review of its use in the treatment of glaucoma and ocular hypertension. Drugs Aging. 2006; 23:977-995.
    • (2006) Drugs Aging , vol.23 , pp. 977-995
    • Frampton, J.E.1    Perry, C.M.2
  • 38
    • 0036263686 scopus 로고    scopus 로고
    • Additive intraocular pressure lowering effect of various medications with latanoprost
    • O'Connor DJ, Martone JF, Mead A. Additive intraocular pressure lowering effect of various medications with latanoprost. Am J Ophthalmol. 2002;133:836-837.
    • (2002) Am J Ophthalmol , vol.133 , pp. 836-837
    • O'Connor, D.J.1    Martone, J.F.2    Mead, A.3
  • 39
    • 33746397955 scopus 로고    scopus 로고
    • Additive effect of dorzolamide or carteolol to latanoprost in primary open-angle glaucoma: A prospective randomized crossover trial
    • Maruyama K, Shirato S. Additive effect of dorzolamide or carteolol to latanoprost in primary open-angle glaucoma: a prospective randomized crossover trial. J Glaucoma. 2006;15: 341-345.
    • (2006) J Glaucoma , vol.15 , pp. 341-345
    • Maruyama, K.1    Shirato, S.2
  • 40
    • 0032419372 scopus 로고    scopus 로고
    • Additive effect of latanoprost and dorzolamide in patients with elevated intraocular pressure
    • Kimal Arici M, Topalkara A, Guler C. Additive effect of latanoprost and dorzolamide in patients with elevated intraocular pressure. Int Ophthalmol. 1998;22:37-42.
    • (1998) Int Ophthalmol , vol.22 , pp. 37-42
    • Kimal Arici, M.1    Topalkara, A.2    Guler, C.3
  • 41
    • 0019788829 scopus 로고
    • Separate and combined effects of timolol maleate and acetazolamide in open-angle glaucoma
    • Berson FG, Epstein DL. Separate and combined effects of timolol maleate and acetazolamide in open-angle glaucoma. Am J Ophthalmol. 1981;92:788-791.
    • (1981) Am J Ophthalmol , vol.92 , pp. 788-791
    • Berson, F.G.1    Epstein, D.L.2
  • 42
    • 0034019026 scopus 로고    scopus 로고
    • Effects of topical nipradilol, a beta blocking agent with alpha blocking and nitroglycerin-like activities, on intraocular pressure and aqueous dynamics in humans
    • Kanno M, Araie M, Koibuchi H, et al. Effects of topical nipradilol, a beta blocking agent with alpha blocking and nitroglycerin-like activities, on intraocular pressure and aqueous dynamics in humans. Br J Ophthalmol. 2000;84: 293-299.
    • (2000) Br J Ophthalmol , vol.84 , pp. 293-299
    • Kanno, M.1    Araie, M.2    Koibuchi, H.3
  • 43
    • 0033825805 scopus 로고    scopus 로고
    • Effects of latanoprost and timolol-XE on hydrodynamics in the normal eye
    • Sponsel WE, Mensah J, Kiel JW, et al. Effects of latanoprost and timolol-XE on hydrodynamics in the normal eye. Am J Ophthalmol. 2000;130:151-159.
    • (2000) Am J Ophthalmol , vol.130 , pp. 151-159
    • Sponsel, W.E.1    Mensah, J.2    Kiel, J.W.3
  • 44
    • 0025970159 scopus 로고
    • Dose-related effects of prostaglandin F2 alpha isopropylester on intraocular pressure, refraction, and pupil diameter in monkeys
    • Crawford KS, Kaufman PL. Dose-related effects of prostaglandin F2 alpha isopropylester on intraocular pressure, refraction, and pupil diameter in monkeys. Invest Ophthalmol Vis Sci. 1991;32:510-519.
    • (1991) Invest Ophthalmol Vis Sci , vol.32 , pp. 510-519
    • Crawford, K.S.1    Kaufman, P.L.2
  • 45
    • 47549102420 scopus 로고    scopus 로고
    • Aqueous humor dynamics in exfoliation syndrome
    • Johnson TV, Fan S, Camras CB, et al. Aqueous humor dynamics in exfoliation syndrome. Arch Ophthalmol. 2008;126:914-920.
    • (2008) Arch Ophthalmol , vol.126 , pp. 914-920
    • Johnson, T.V.1    Fan, S.2    Camras, C.B.3
  • 46
    • 0033044222 scopus 로고    scopus 로고
    • Acute versus chronic effects of brimonidine on aqueous humor dynamics in ocular hypertensive patients
    • Toris CB, Camras CB, Yablonski ME. Acute versus chronic effects of brimonidine on aqueous humor dynamics in ocular hypertensive patients. Am J Ophthalmol. 1999;128:8-14.
    • (1999) Am J Ophthalmol , vol.128 , pp. 8-14
    • Toris, C.B.1    Camras, C.B.2    Yablonski, M.E.3
  • 47
    • 0033118793 scopus 로고    scopus 로고
    • Aqueous humor dynamics in the aging human eye
    • Toris CB, Yablonski ME, Wang YL, et al. Aqueous humor dynamics in the aging human eye. Am J Ophthalmol. 1999;127: 407-412.
    • (1999) Am J Ophthalmol , vol.127 , pp. 407-412
    • Toris, C.B.1    Yablonski, M.E.2    Wang, Y.L.3
  • 48
    • 0842287985 scopus 로고    scopus 로고
    • Studies on the mechanism of action of timolol and on the effects of suppression and redirection of aqueous flow on outflow facility
    • Kiland JA, Gabelt BT, Kaufman PL. Studies on the mechanism of action of timolol and on the effects of suppression and redirection of aqueous flow on outflow facility. Exp Eye Res. 2004;78:639-651.
    • (2004) Exp Eye Res , vol.78 , pp. 639-651
    • Kiland, J.A.1    Gabelt, B.T.2    Kaufman, P.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.