Blocking fasciola hepatica's energy metabolism - a pilot study of vaccine potential of a novel gene - phosphoglycerate kinase

Veterinary Parasitology

Volumn 172, Issue 3-4, 2010, Pages 229-237

  Jaros, Slawomir ^a,c   Jaros, Dorota ^b,d   Wesolowska, Agnieszka ^a   Zygner, Wojciech ^b   Wedrychowicz, Halina ^a,b  

^a W STEFA SKI INSTITUTE OF PARASITOLOGY   (Poland)

^b WARSAW UNIVERSITY OF LIFE SCIENCES   (Poland)

^c Laboratory of Molecular Biology   (Poland)

^d INSTITUTE OF MEDICAL BIOLOGY   (Poland)

Author keywords

Fasciola hepatica phosphoglycerate kinase; Recombinant antigen; Vaccination

Indexed keywords

DNA VACCINE; PHOSPHOGLYCERATE KINASE; RECOMBINANT VACCINE;

ACTIVE IMMUNIZATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; ENERGY METABOLISM; FASCIOLA HEPATICA; FASCIOLIASIS; FEMALE; IMMUNE RESPONSE; INFECTION PREVENTION; MALE; NONHUMAN; RAT; SEX DIFFERENCE;

ANIMALS; ANTIBODIES, HELMINTH; ANTIGENS, HELMINTH; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; FASCIOLA HEPATICA; FASCIOLIASIS; FEMALE; MALE; PHOSPHOGLYCERATE KINASE; PILOT PROJECTS; RATS; VACCINATION; VACCINES, SYNTHETIC;

FASCIOLA HEPATICA; RATTUS;

EID: 77956010843     PISSN: 03044017     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetpar.2010.05.008     Document Type: Article

References (21)

1. Behm C.A. Pathophysiology of Fasciola hepatica infections in mammals. Immunology, Pathology and Control of Fasciolosis 1994, 37. MSD AGVET, Izmir. J.C. Boray (Ed.).
2. Dalton J.P., McGongile S., Rolph T.P., Andrews S.J. Induction of protective immunity in cattle against infection with Fasciola hepatica by vaccination with cathepsin L proteinases and hemoglobin. Infect. Immun. 1996, 64:5066-5074.
3. Hayes T.J., Bailer J., Mitrovic M. Studies on the transfer of immunity to Fasciola hepatica in the rat. J. Parasitol. 1974, 60:930-934.
4. Hong S.J., Seong K.Y., Sohn W.M., Song K.Y. Molecular cloning and immunological characterization of phosphoglycerate kinase from Clonorchis sinensis. Mol. Biochem. Parasitol. 2000, 108:207-216.
5. Jaros S., Januszkiewicz K., Smaga-Kozlowska K., Wesolowska A., Zygner W., Wedrychowicz H. A comparison of protectivity of cDNA vaccination against Fasciola hepatica infections using a novel cathepsin L (FhPcW1) and previously tested cathepsin Ls. Wiadomosci Parazytologiczne 2007, 53:72. (supplement - Conference Materials: XXI Congress of the Polish Parsitological Society, Miedzyzdroje, Poland, 5-7th September 2007).
6. Kesik M., Jedlina-Panasiuk L., Kozak-Cieszczyk M., Plucienniczak A., Wedrychowicz H. Enteral vaccination of rats against Fasciola hepatica Rusing recombinant cysteine proteinase (cathepsin L1). Vaccine 2007, 25:3619-3628.
7. Kofta W., Mieszczanek J., Plucienniczak G., Wedrychowicz H. Successful DNA immunisation of rats against fasciolosis. Vaccine 2000, 18:2985-2990.
8. Lozes E., Huygen K., Content J., Denis O., Montgomery D.L., Yawman A.M., Vandenbussche P., van Vooren J.P., Drowart A.M., Ulmer J.B., Liu M.A. Immunogenicity and efficacy of a tuberculosis DNA vaccine encoding the components of the secreted antigen 85 complex. Vaccine 1997, 15:830-833.
9. Mas-Coma S., Bargues M.D., Esteban J.G. Human fasciolosis. Fasciolosis 1999, 411-434. CAB International, Wallingford, UK. J.P. Dalton (Ed.).
10. Morrison C.A., Colin T., Sexton J.L., Bowen F., Wicker J., Friedel T., Spithill T.W. Protection of cattle against Fasciola hepatica by vaccination with glutathione S-transferase. Vaccine 1996, 14:1603-1612.
11. Muro A., Ramajo V., Lopez J., Simon F., Hillyer G.V. Fasciola hepatica: vaccination of rabbits with native and recombinant antigens related to fatty acid binding proteins. Vet. Parasitol. 1997, 69:219-229.
12. O'Neil S.M., Parkinson M., Strauss W., Angles R., Dalton J.P. Immunodiagnosis of Fasciola hepatica infection (fascioliasis) in a human population in the Bolivian altiplano using purified cathepsin L cysteine protease. Am. J. Trop. Med. Hyg. 1998, 58:417-423.
13. Poitou I., Baeza E., Boulard C. Humoral and cellular immune responses in rats during a primary infestation with Fasciola hepatica. Vet. Parasitol. 1992, 45:59-71.
14. Rajasekariah G.R., Howell M.J. Fasciola hepatica: role of developmental stages in the rat's resistance to challenge. Exp. Parasitol. 1978, 44:233-238.
15. Reddington J.J., Wes Leid R., Wescott R.B. Effect of inoculum on the size and location of Fasciola hepatica subsequently recovered from the livers of rats. Vet. Parasitol. 1984, 14:13-19.
16. Rokni M.B., Massoud J., O'Neil S.M., Parkinson M., Dalton J.P. Diagnosis of human fasciolosis in the Gilan province of northern Iran: application of cathepsin L-ELISA. Diagn. Microbiol. Infect. Dis. 2002, 44:175-179.
17. Spithill T.W., Smooker P.M., Sexton J.L., Bozas E., Morrison C.A., Creaney J., Parsons J.C. Development of vaccines against Fasciola hepatica. Fasciolosis 1999, 377-410. CAB International, Wallingford, UK. J.P. Dalton (Ed.).
18. Sutherland I. Spectrum of activity of anthelmintics. Novartis Animal Health: Anthelmintics and Resistance: A Review 2007, pp. 17-21.
19. von Samson-Himmelstjerna G. Mode of action of current anthelmintic drug classes. Novartis Animal Health: Anthelmintics and Resistance: A Review 2007, pp. 23-27.
20. Wedrychowicz H., Lamparska M., Kesik M., Kotomski G., Mieszczanek J., Jedlina-Panasiuk L., Plucienniczak A. The immune response of rats to vaccination with the cDNA or protein forms of the cysteine proteinase of Fasciola hepatica. Vet. Immunol. Immunopathol. 2003, 94:83-93.
21. Xu D., Liew F.Y. Genetic vaccination against leishmaniasis. Vaccine 1994, 12:1534-1536.