The impact of lymph node density on survival of cervical cancer patients

British Journal of Cancer

Volumn 103, Issue 5, 2010, Pages 613-616

  Polterauer, S ^a   Hefler, L ^a   Seebacher, V ^a   Rahhal, J ^a   Tempfer, C ^a   Horvat, R ^a   Reinthaller, A ^a   Grimm, C ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

cervical cancer; lymph node density; prognosis

Indexed keywords

ADULT; ARTICLE; CANCER GRADING; CANCER PATIENT; CANCER STAGING; CANCER SURVIVAL; DISEASE FREE SURVIVAL; HISTOPATHOLOGY; HUMAN; LYMPH NODE; MAJOR CLINICAL STUDY; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; UTERINE CERVIX CANCER;

ADULT; FEMALE; HUMANS; LYMPH NODES; LYMPHATIC METASTASIS; MIDDLE AGED; PROGNOSIS; UTERINE CERVICAL NEOPLASMS;

EID: 77955984413     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6605801     Document Type: Article

References (18)

1. Cai T, Nesi G, Tinacci G, Giubilei G, Gavazzi A, Mondaini N, Zini E, Bartoletti R (2009) Clinical importance of lymph node density in predicting outcome of prostate cancer patients. J Surg Res epub ahead of print 6 June 2009; doi:10.1016/j.jss.2009.05.004
2. Chan JK, Kapp DS, Cheung MK, Osann K, Shin JY, Cohn D, Seid PL (2007) The impact of the absolute number and ratio of positive lymph nodes on survival of endometrioid uterine cancer patients. Br J Cancer 97: 605-611
3. Committee on Practice Bulletins-Gynecology (2002) ACOG practice bulletin. Diagnosis and treatment of cervical carcinomas, number 35, May 2002. Obstet Gynecol 99: 855-867
4. Delgado G, Bundy B, Zaino R, Sevin BU, Creasman WT, Major F (1990) Prospective surgical-pathological study of disease-free interval in patients with stage IB squamous cell carcinoma of the cervix: a Gynecologic Oncology Group study. Gynecol Oncol 38: 352-357
5. Gil Z, Carlson DL, Boyle JO, Kraus DH, Shah JP, Shaha AR, Singh B, Wong RJ, Patel SG (2009) Lymph node density is a significant predictor of outcome in patients with oral cancer. Cancer 15: 5700-5710
6. Green J, Kirwan J, Tierney J, Vale C, Symonds P, Fresco L, Williams C, Collingwood M (2005) Concomitant chemotherapy and radiation therapy for cancer of the uterine cervix. Cochrane Database Syst Rev Issue 3. Art. no. CD002225
7. Herr HW (2003) Superiority of ratio based lymph node staging for bladder cancer. J Urol 169: 943-945
8. Kassouf W, Agarwal PK, Herr HW, Munsell MF, Spiess PE, Brown GA, Pisters L, Grossman HB, Dinney CP, Kamat AM (2008) Lymph node density is superior to TNM nodal status in predicting disease-specific survival after radical cystectomy for bladder cancer: analysis of pooled data from MDACC and MSKCC. J Clin Oncol 26: 121-126
9. Lai CH, Huang KG, Hong JH, Lee CL, Chou HH, Chang TC, Hsueh S, Huang HJ, Ng KK, Tsai CS (2003) Randomized trial of surgical staging (extraperitoneal or laparoscopic) versus clinical staging in locally advanced cervical cancer. Gynecol Oncol 89: 160
10. Lee YN, Wang KL, Lin MH, Liu CH, Wang KG, Lan CC, Chuang JT, Chen AC, Wu CC (1989) Radical hysterectomy with pelvic lymph node dissection for treatment of cervical cancer: a clinical review of 954 cases. Gynecol Oncol 32: 135-142
11. Ooki A, Yamashita K, Kobayashi N, Katada N, Sakuramoto S, Kikuchi S, Watanabe M (2007) Lymph node metastasis density and growth pattern as independent prognostic factors in advanced esophageal squamous cell carcinoma. World J Surg 31: 2184-2191
12. Polterauer S, Hefler LA, Petry M, Seebacher V, Tempfer C, Reinthaller A (2008) The perioperative morbidity of laparoscopic pelvic lymph node staging in patients with advanced cervical cancer. Anticancer Res 28: 1849-1851
13. Singh N, Arif S (2004) Histopathologic parameters of prognosis in cervical cancer\a review. Int J Gynecol Cancer 14: 741-750
14. Svatek RS, Munsell M, Kincaid JM, Hegarty P, Slaton JW, Busby JE, Gaston KE, Spiess PE, Pagliaro LC, Tamboli P, Pettaway CA (2009) Association between lymph node density and disease specific survival in patients with penile cancer. J Urol 182: 2721-2727
15. Tanaka Y, Sawada S, Murata T (1984) Relationship between lymph node metastases and prognosis in patients irradiated postoperatively for carcinoma of the uterine cervix. Acta Radiol Oncol 23: 455-459
16. Tseng JY, Yen MS, Twu NF, Lai CR, Horng HC, Tseng CC, Chao KC, Juang CM (2010) Prognostic nomogram for overall survival in stage IIB-IVA cervical cancer patients treated with concurrent chemoradiotherapy. Am J Obstet Gynecol 202: 174
17. Vinh-Hung V, Verkooijen HM, Fioretta G, Neyroud-Caspar I, Rapiti E, Vlastos G, Deglise C, Usel M, Lutz JM, Bouchardy C (2009) Lymph node ratio as an alternative to pN staging in node-positive breast cancer. J Clin Oncol 27: 1062-1068
18. Yamashita K, Ooki A, Sakuramoto S, Kikuchi S, Katada N, Kobayashi N, Watanabe M (2008) Lymph node metastasis density (ND)-factor association with malignant degree and ND40 as 'non-curative factor' in gastric cancer. Anticancer Res 28: 435-441