Raman spectral imaging of single cancer cells: Probing the impact of sample fixation methods

Analytical and Bioanalytical Chemistry

Volumn 397, Issue 7, 2010, Pages 2727-2737

  Draux, Florence ^a   Gobinet, Cyril ^a   Sulé Suso, Josep ^b   Trussardi, Aurélie ^a   Manfait, Michel ^a   Jeannesson, Pierre ^a   Sockalingum, Ganesh D ^a  

^a UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

^b KEELE UNIVERSITY   (United Kingdom)

Author keywords

Cell fixation; Raman microimaging; Spectral cytology; Statistical analysis

Indexed keywords

AIR DRYING; BIOCHEMICAL INFORMATION; CANCER CELLS; CELL FIXATION; CELLULAR COMPARTMENTS; CLINICAL PRACTICES; CLUSTER CENTERS; FITTING PROCEDURE; FIXATION METHODS; FORMALIN; FORMALIN FIXATION; HIERARCHICAL CLUSTER ANALYSIS; ISOLATED CELLS; LIVING CELL; LIVING CONDITIONS; MICRO-RAMAN; MODEL SPECTRA; MOLECULAR LEVELS; MORPHOLOGICAL MODIFICATION; PREPARATION METHOD; PRINCIPAL COMPONENTS ANALYSIS; RAMAN MICROIMAGING; RAMAN SPECTRAL IMAGING; SAMPLE PREPARATION; SAMPLE PREPARATION METHODS; SPECTRAL CYTOLOGY; SPECTRAL IMAGES; SPECTRAL INFORMATION; STATISTICAL ANALYSIS;

CELLS; CLUSTER ANALYSIS; CYTOLOGY; DRYING; FORMALDEHYDE; HIERARCHICAL SYSTEMS; MASS SPECTROMETRY; NUCLEIC ACIDS; PRINCIPAL COMPONENT ANALYSIS; PROTEINS; RAMAN SCATTERING; RAMAN SPECTROSCOPY; RNA;

BIOINFORMATICS;

CHEMISTRY; CONFERENCE PAPER; EVALUATION; GENETICS; HUMAN; METABOLISM; METHODOLOGY; NEOPLASM; PATHOLOGY; RAMAN SPECTROMETRY; TISSUE FIXATION; TUMOR CELL LINE; EVALUATION STUDY; PROCEDURES;

CELL LINE, TUMOR; HUMANS; NEOPLASMS; SPECTRUM ANALYSIS, RAMAN; TISSUE FIXATION;

EID: 77955982590     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-010-3759-8     Document Type: Conference Paper

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