Clinical utility gene card for: Lynch syndrome (MLH1, MSH2, MSH6, PMS2)

European Journal of Human Genetics

Volumn 18, Issue 9, 2010, Pages 1069-

  Rahner, Nils ^a   Steinke, Verena ^a   Schlegelberger, Brigitte ^b   Olschwang, Sylviane ^c   Eisinger, François ^c   Hutter, Pierre ^d  

^a UNIVERSITY OF BONN   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c INSTITUT PAOLI CALMETTES   (France)

^d Institut Central des Hopitaux Valaisans   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

GENE MUTATION; GENETIC DISORDER; GENETIC SCREENING; HEMOCHROMATOSIS; MORBIDITY; PRIORITY JOURNAL; QUESTIONNAIRE; RISK ASSESSMENT; SHORT SURVEY; ARTICLE; CHROMOSOME MAP; GENETIC PREDISPOSITION; GENETICS; GERMANY; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HUMAN; MUTATION; SENSITIVITY AND SPECIFICITY;

ADENOSINE TRIPHOSPHATASE; DNA BINDING PROTEIN; G T MISMATCH BINDING PROTEIN; G-T MISMATCH-BINDING PROTEIN; MLH1 PROTEIN, HUMAN; MSH2 PROTEIN, HUMAN; NUCLEAR PROTEIN; PMS2 PROTEIN, HUMAN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN MSH2; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATASES; CHROMOSOME MAPPING; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; GENETIC PREDISPOSITION TO DISEASE; GERMANY; HUMANS; MUTATION; MUTS HOMOLOG 2 PROTEIN; NUCLEAR PROTEINS; SENSITIVITY AND SPECIFICITY;

EID: 77955982440     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/ejhg.2009.232     Document Type: Short Survey

References (5)

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2. LoughreyMB,Waring PM, Tan A et al: Incorporation of somatic BRAF mutation testing into an algorithm for the investigation of hereditary non-polyposis colorectal cancer. Fam Cancer 2007; 6: 301-310.
3. Grover S, Syngal S: Genetic testing in gastroenterology: Lynch syndrome. Best Pract Res Clin Gastroenterol 2009; 23: 185-196.
4. Stoffel E, Mukherjee B, Raymond VM et al: Calculation of risk of colorectal and endometrial cancer among patients with Lynch syndrome. Gastroenterology 2009; 137: 1621-1627.
5. Krausz C, Quintana-Murci L, McElreavey K: Prognostic value of deletion analysis: what is the clinical prognostic value of Y chromosome microdeletion analysis? Hum Reprod 2000; 15: 1431-1434.