Conjugates of betulin derivatives with AZT as potent anti-HIV agents

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 17, 2010, Pages 6451-6469

  Xiong, Juan ^a   Kashiwada, Yoshiki ^a   Chen, Chin Ho ^b   Qian, Keduo ^c   Morris Natschke, Susan L ^c   Lee, Kuo Hsiung ^c   Takaishi, Yoshihisa ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b DUKE UNIVERSITY   (United States)

^c University of North Carolina   (United States)

Author keywords

AZT; Betulin; Conjugate; HIV 1

Indexed keywords

1 (3' AZIDO 3' DEOXYTHYMIDINE 5' YL) 4 (3 O GLUTARYLLUP 28 YL) 2,2 DIMETHYLSUCCINATE; 1 (3' AZIDO 3' DEOXYTHYMIDINE 5' YL) 4 [3 O (3',3' DIMETHYLSUCCINYL)LUP 20(29)EN 28 YL] 2,2 DIMETHYLSUCCINATE; 1 (3' AZIDO 3' DEOXYTHYMIDINE 5' YL) 4 [3 O (3',3' DIMETHYLSUCCINYL)LUP 28 YL] 2,2 DIMETHYLSUCCINATE; 3' AZIDO 3' DEOXYTHYMIDINE 5' YL 3 O (3',3' DIMETHYLGLUTARYL)LUP 20(29)EN 28 YL 3,3 DIMETHYLGLUTARATE; 3' AZIDO 3' DEOXYTHYMIDINE 5' YL 3 O (3',3' DIMETHYLGLUTARYL)LUP 28 YL 3,3 DIMETHYLGLUTARATE; 3' AZIDO 3' DEOXYTHYMIDINE 5' YL 3 O (3',3' DIMETHYLSUCCINYL) LUP 20(29)EN 28 YL SUCCINATE; 3' AZIDO 3' DEOXYTHYMIDINE 5' YL 3 O (3',3' DIMETHYLSUCCINYL)LUP 20(29)EN 28 YL 3,3 DIMETHYLGLUTARATE; 3' AZIDO 3' DEOXYTHYMIDINE 5' YL 3 O (3',3' DIMETHYLSUCCINYL)LUP 28 YL 3,3 DIMETHYLGLUTARATE; 3' AZIDO 3' DEOXYTHYMIDINE 5' YL 3 O (30,30 DIMETHYLSUCCINYL)LUP 20(29)EN 28 YL GLUTARATE; 3' AZIDO 3' DEOXYTHYMIDINE 5' YL 3 O GLUTARYLLUP 28 YL 3,3 DIMETHYLGLUTARATE; 3' AZIDO 3' DEOXYTHYMIDINE 5' YL 3 O GLUTARYLLUP 28 YL GLUTARATE; 4 (3' AZIDO 3' DEOXYTHYMIDINE 5' YL) 1 (3 O GLUTARYLLUP 28 YL) 2,2 DIMETHYLSUCCINATE; 4 (3' AZIDO 3' DEOXYTHYMIDINE 5' YL) 1 [3 O (3',3' DIMETHYLSUCCINYL)LUP 20(29)EN 28 YL] 2,2 DIMETHYLSUCCINATE; 4 (3' AZIDO 3' DEOXYTHYMIDINE 5' YL) 1 [3 O (3',3' DIMETHYLSUCCINYL)LUP 28 YL] 2,2 DIMETHYLSUCCINATE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; BETULIN; BEVIRIMAT; UNCLASSIFIED DRUG; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; LYMPHOCYTE; VIRUS INHIBITION;

ANTI-HIV AGENTS; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; HIV-1; HUMANS; TRITERPENES; ZIDOVUDINE;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 77955982012     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.06.092     Document Type: Article

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