Use of abacavir in 30 HIV-infected children from Durban, South Africa: Report from a pilot study

Pediatric Infectious Disease Journal

Volumn 29, Issue 9, 2010, Pages 890-

  Bobat, Raziya ^a   Kindra, Gurpreet ^a   Kiepiela, Photini ^b   Reddy, Shabashini ^b   Jeena, Prakash M ^a   Adhikari, Miriam ^a   Coovadia, Hoosen M ^b  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b UNIVERSITY OF KWAZULU NATAL   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; ABACAVIR PLUS LAMIVUDINE PLUS ZIDOVUDINE; HLA B ANTIGEN;

ALLELE; CHILD; CLINICAL ARTICLE; DRUG HYPERSENSITIVITY; DRUG SAFETY; DRUG WITHDRAWAL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; LETTER; NONHUMAN; PRIORITY JOURNAL; RASH; SOUTH AFRICA; TREATMENT DURATION; TREATMENT OUTCOME;

EID: 77955969920     PISSN: 08913668     EISSN: 15320987     Source Type: Journal    
DOI: 10.1097/INF.0b013e3181e5a0fe     Document Type: Letter

References (5)

1. Rabie H, Henning KL, Schoeman P, et al. Abacavir: its use and hypersensitivity. South Afr J HIV Med. 2009;10:81-84.
2. Kiepiela P, Leslie AJ, Honeyborne I, et al. Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA. Nature. 2004;432:769-775.
3. Thobakgale CF, Ramduth D, Reddy S, et al. Human immunodeficiency virus-specific CD8 + T-cell activity is detectable from birth in the majority of in utero-infected infants. J Virol. 2007;81:12775-12784.
4. Thobakgale CF, Prendergast A, Crawford H, et al. Impact of HLA in mother and child on disease progression of pediatric human immunodeficiency virus type 1 infection. J Virol. 2009;83: 10234-10244.
5. Calza L, Rosseti N, Biagetti C, et al. Abacavir-induced reaction with fever and severe skin rash in a patient tested human leukocyte antigen-B*5701 negative. Int J STD AIDS. 2009; 20:276-277.