Root surface conditioning with bone morphogenetic protein-2 facilitates cementum-like tissue deposition in beagle dogs

Journal of Periodontal Research

Volumn 45, Issue 5, 2010, Pages 658-663

  Miyaji, H ^a   Sugaya, T ^a   Ibe, K ^b   Ishizuka, R ^a   Tokunaga, K ^a   Kawanami, M ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b Maruyama Kita Nijyo Dental Clinic   (Japan)

Author keywords

Bone morphogenetic protein 2; Cementum like tissue; Dog; Root dentin surface conditioning

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-2; RECOMBINANT PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL; ARTICLE; DENTIN; DOG; DRUG EFFECT; FEMALE; PERIODONTAL LIGAMENT; PERIODONTIUM; PHYSIOLOGY; PREVENTIVE DENTISTRY; RANDOMIZATION; REGENERATION; TOOTH DEVELOPMENT; TOOTH ROOT;

ANIMALS; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEINS; CEMENTOGENESIS; DENTIN; DOGS; EPITHELIAL ATTACHMENT; FEMALE; PERIODONTAL LIGAMENT; RANDOM ALLOCATION; RECOMBINANT PROTEINS; REGENERATION; ROOT PLANING; TOOTH ROOT; TRANSFORMING GROWTH FACTOR BETA;

EID: 77955965806     PISSN: 00223484     EISSN: 16000765     Source Type: Journal    
DOI: 10.1111/j.1600-0765.2010.01281.x     Document Type: Article

References (24)

1. Bartold PM, McCulloch CA, Narayanan AS, Pitaru S. Tissue engineering: a new paradigm for periodontal regeneration based on molecular and cell biology. Periodontol 2000 2000, 24:253-269.
2. Nyman S, Karring T, Lindhe J, Plantén S. Healing following implantation of periodontitis-affected roots into gingival connective tissue. J Clin Periodontol 1980, 7:394-401.
3. Lasho DJ, O'Leary TJ, Kafrawy AH. A scanning electron microscope study of the effects of various agents on instrumented periodontally involved root surfaces. J Periodontol 1983, 54:210-220.
4. Pitaru S, Gray A, Aubin JE, Melcher AH. The influence of the morphological and chemical nature of dental surfaces on the migration, attachment, and orientation of human gingival fibroblasts in vitro. J Periodontal Res 1984, 19:408-418.
5. Fardal O, Lowenberg BF. A quantitative analysis of the migration, attachment, and orientation of human gingival fibroblasts to human dental root surfaces in vitro. J Periodontol 1990, 61:529-535.
6. Blomlöf J, Lindskog S. Root surface texture and early cell and tissue colonization after different etching modalities. Eur J Oral Sci 1995, 103:17-24.
7. Zaman KU, Sugaya T, Hongo O, Kato H. A study of attached and oriented human periodontal ligament cells to periodontally diseased cementum and dentin after demineralizing with neutral and low pH etching solution. J Periodontol 2000, 71:1094-1099.
8. Park JB, Matsuura M, Han KY. Periodontal regeneration in class III furcation defects of beagle dogs using guided tissue regenerative therapy with platelet-derived growth factor. J Periodontol 1995, 66:462-477.
9. Katagiri T, Yamaguchi A, Ikeda T. The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2. Biochem Biophys Res Commun 1990, 172:295-299.
10. Gong L, Hoshi K, Ejiri S, Nakajima T, Shingaki S, Ozawa H. Bisphosphonate incadronate inhibits maturation of ectopic bone induced by recombinant human bone morphogenetic protein-2. J Bone Miner Metab 2003, 21:5-11.
11. Nanno K, Sugiyasu K, Daimon T, Yoshikawa H, Myoui A. Synthetic alginate is a carrier of OP-1 for bone induction. Clin Orthop Relat Res 2009, 467:3149-3155.
12. Zaman KU, Sugaya T, Kato H. Effect of recombinant human platelet-derived growth factor-BB and bone morphogenetic protein-2 application to demineralized dentin on early periodontal ligament cell response. J Periodontal Res 1999, 34:244-250.
13. Miyaji H, Sugaya T, Miyamoto T, Kato K, Kato H. Hard tissue formation on dentin surfaces applied with recombinant human bone morphogenetic protein-2 in the connective tissue of the palate. J Periodontal Res 2002, 37:204-209.
14. Miyaji H, Sugaya T, Kato H. Effect of rhBMP-2 applied dentin on alkaline phosphatase activity and mineralized nodule formation in gingival fibroblasts. J Jpn Soc Periodontol 2000, 42:247-254.
15. Miyaji H, Sugaya T, Kato K, Kawamura N, Tsuji H, Kawanami M. Dentin resorption and cementum-like tissue formation by bone morphogenetic protein application. J Periodontal Res 2006, 41:311-315.
16. Takita H, Tsuruga E, Ono I, Kuboki Y. Enhancement by bFGF of osteogenesis induced by rhBMP-2 in rats. Eur J Oral Sci 1997, 105:588-592.
17. Akizuki T, Oda S, Komaki M. Application of periodontal ligament cell sheet for periodontal regeneration: a pilot study in beagle dogs. J Periodontal Res 2005, 40:245-251.
18. Zhou G, Liu W, Cui L, Wang X, Liu T, Cao Y. Repair of porcine articular osteochondral defects in non-weightbearing areas with autologous bone marrow stromal cells. Tissue Eng 2006, 12:3209-3221.
19. Nishida K, Yamato M, Hayashida Y. Functional bioengineered corneal epithelial sheet grafts from corneal stem cells expanded ex vivo on a temperature-responsive cell culture surface. Transplantation 2004, 77:379-385.
20. Shipley GD, Pittelkow MR, Willie JJ, Scott RE, Moses HL. Reversible inhibition of normal human prokeratinocyte proliferation by type β transforming growth factor-growth inhibitor in serum-free medium. Cancer Res 1986, 46:2068-2071.
21. Sigurdsson TJ, Lee MB, Kubota K, Turek TJ, Wozney JM, Wikesjö UM. Periodontal repair in dogs: recombinant human bone morphogenetic protein-2 significantly enhances periodontal regeneration. J Periodontol 1995, 66:131-138.
22. Wikesjö UM, Guglielmoni P, Promsudthi A. Periodontal repair in dogs: effect of rhBMP-2 concentration on regeneration of alveolar bone and periodontal attachment. J Clin Periodontol 1999, 26:392-400.
23. Saito E, Saito A, Kawanami M. Favorable healing following space creation in rhBMP-2-induced periodontal regeneration of horizontal circumferential defects in dogs with experimental periodontitis. J Periodontol 2003, 74:1808-1815.
24. Takahashi D, Odajima T, Morita M, Kawanami M, Kato H. Formation and resolution of ankylosis under application of recombinant human bone morphogenetic protein-2 (rhBMP-2) to class III furcation defects in cats. J Periodontal Res 2005, 40:299-305.