메뉴 건너뛰기




Volumn 7, Issue SUPPL. 3, 2010, Pages

Live cell imaging of mechanotransduction

Author keywords

Fluorescence resonance energy transfer; Mechanotransduction; Shear stress; Stretch; Substrate stiffness

Indexed keywords

BIOSENSORS; ENERGY TRANSFER; FLUORESCENCE; RESONANCE; SHEAR STRESS; STIFFNESS; STRENGTH OF MATERIALS; TECHNOLOGY;

EID: 77955947356     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2010.0042.focus     Document Type: Review
Times cited : (24)

References (97)
  • 1
    • 33845751079 scopus 로고    scopus 로고
    • Directed evolution of a monomeric, bright and photostable version of Clavularia cyan fluorescent protein: Structural characterization and applications in fluorescence imaging
    • doi:10.1042/BJ20060874
    • Ai, H. W., Henderson, J. N., Remington, S. J. & Campbell, R. E. 2006 Directed evolution of a monomeric, bright and photostable version of Clavularia cyan fluorescent protein: structural characterization and applications in fluorescence imaging. Biochem. J. 400, 531-540. (doi:10.1042/BJ20060874)
    • (2006) Biochem. J. , vol.400 , pp. 531-540
    • Ai, H.W.1    Henderson, J.N.2    Remington, S.J.3    Campbell, R.E.4
  • 2
    • 33746907024 scopus 로고    scopus 로고
    • Subcellular dynamics of protein kinase A activity visualized by FRET-based reporters
    • doi:10. 1016/j.bbrc.2006.07.136
    • Allen, M. D. & Zhang, J. 2006 Subcellular dynamics of protein kinase A activity visualized by FRET-based reporters. Biochem. Biophys. Res. Commun. 348, 716-721. (doi:10. 1016/j.bbrc.2006.07.136)
    • (2006) Biochem. Biophys. Res. Commun. , vol.348 , pp. 716-721
    • Allen, M.D.1    Zhang, J.2
  • 3
    • 4644318980 scopus 로고    scopus 로고
    • Cyclic, mechanical compression enhances chondrogenesis of mesenchymal progenitor cells in tissue engineering scaffolds
    • Angele, P. et al. 2004 Cyclic, mechanical compression enhances chondrogenesis of mesenchymal progenitor cells in tissue engineering scaffolds. Biorheology 41, 335-346.
    • (2004) Biorheology , vol.41 , pp. 335-346
    • Angele, P.1
  • 4
    • 0345687176 scopus 로고    scopus 로고
    • Src kinase activation by direct interaction with the integrin beta cytoplasmic domain
    • doi:10.1073/pnas.2336149100
    • Arias-Salgado, E. G., Lizano, S., Sarkar, S., Brugge, J. S., Ginsberg, M. H. & Shattil, S. J. 2003 Src kinase activation by direct interaction with the integrin beta cytoplasmic domain. Proc. Natl Acad. Sci. USA 100, 13 298-13 302. (doi:10.1073/pnas.2336149100)
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 13298-13302
    • Arias-Salgado, E.G.1    Lizano, S.2    Sarkar, S.3    Brugge, J.S.4    Ginsberg, M.H.5    Shattil, S.J.6
  • 5
    • 69149102112 scopus 로고    scopus 로고
    • Role of the actin cytoskeleton in tuning cellular responses to external mechanical stress
    • doi:10.1111/j.1600-0838.2009.00928.x
    • Asparuhova, M. B., Gelman, L. & Chiquet, M. 2009 Role of the actin cytoskeleton in tuning cellular responses to external mechanical stress. Scand. J. Med. Sci. Sports 19, 490-499. (doi:10.1111/j.1600-0838.2009.00928.x)
    • (2009) Scand. J. Med. Sci. Sports , vol.19 , pp. 490-499
    • Asparuhova, M.B.1    Gelman, L.2    Chiquet, M.3
  • 6
    • 70450267353 scopus 로고    scopus 로고
    • Real-time measurements of cAMP production in live Dictyostelium cells
    • doi:10.1242/jcs.051987
    • Bagorda, A., Das, S., Rericha, E. C., Chen, D., Davidson, J. & Parent, C. A. 2009 Real-time measurements of cAMP production in live Dictyostelium cells. J. Cell Sci. 122, 3907-3914. (doi:10.1242/jcs.051987)
    • (2009) J. Cell Sci. , vol.122 , pp. 3907-3914
    • Bagorda, A.1    Das, S.2    Rericha, E.C.3    Chen, D.4    Davidson, J.5    Parent, C.A.6
  • 7
    • 0034304906 scopus 로고    scopus 로고
    • The versatility and universality of calcium signalling
    • doi:10.1038/35036035
    • Berridge, M. J., Lipp, P. & Bootman, M. D. 2000 The versatility and universality of calcium signalling. Nat. Rev. Mol. Cell Biol. 1, 11-21. (doi:10.1038/35036035)
    • (2000) Nat. Rev. Mol. Cell Biol. , vol.1 , pp. 11-21
    • Berridge, M.J.1    Lipp, P.2    Bootman, M.D.3
  • 8
    • 30744439311 scopus 로고    scopus 로고
    • A dual parameter FRET probe for measuring PKC and PKA activity in living cells
    • doi:10.1021/ja0562200
    • Brumbaugh, J., Schleifenbaum, A., Gasch, A., Sattler, M. & Schultz, C. 2006 A dual parameter FRET probe for measuring PKC and PKA activity in living cells. J. Am. Chem. Soc. 128, 24-25. (doi:10.1021/ja0562200)
    • (2006) J. Am. Chem. Soc. , vol.128 , pp. 24-25
    • Brumbaugh, J.1    Schleifenbaum, A.2    Gasch, A.3    Sattler, M.4    Schultz, C.5
  • 10
    • 33750366860 scopus 로고    scopus 로고
    • G protein-coupled receptors sense fluid shear stress in endothelial cells
    • doi:10.1073/pnas.0607224103
    • Chachisvilis, M., Zhang, Y. L. & Frangos, J. A. 2006 G protein-coupled receptors sense fluid shear stress in endothelial cells. Proc. Natl Acad. Sci. USA 103, 15 463-15 468. (doi:10.1073/pnas.0607224103)
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 15463-15468
    • Chachisvilis, M.1    Zhang, Y.L.2    Frangos, J.A.3
  • 11
    • 23444431611 scopus 로고
    • Green fluorescent protein as a marker for gene expression
    • doi:10.1126/science.8303295
    • Chalfie, M., Tu, Y., Euskirchen, G., Ward, W. W. & Prasher, D. C. 1994 Green fluorescent protein as a marker for gene expression. Science 263, 802-805. (doi:10.1126/science.8303295)
    • (1994) Science , vol.263 , pp. 802-805
    • Chalfie, M.1    Tu, Y.2    Euskirchen, G.3    Ward, W.W.4    Prasher, D.C.5
  • 12
    • 67650321832 scopus 로고    scopus 로고
    • PECAM-1 is necessary for flow-induced vascular remodeling
    • doi:10.1161/ATVBAHA.109. 186692
    • Chen, Z. & Tzima, E. 2009 PECAM-1 is necessary for flow-induced vascular remodeling. Arterioscler. Thromb. Vasc. Biol. 29, 1067-1073. (doi:10.1161/ATVBAHA.109. 186692)
    • (2009) Arterioscler. Thromb. Vasc. Biol. , vol.29 , pp. 1067-1073
    • Chen, Z.1    Tzima, E.2
  • 13
    • 39749098357 scopus 로고    scopus 로고
    • Effects of cyclic mechanical stretching on the mRNA expression of tendon/ligament-related and osteoblast-specific genes in human mesenchymal stem cells
    • doi:10.1080/03008200701818561
    • Chen, Y. J., Huang, C. H., Lee, I. C., Lee, Y. T., Chen, M. H. & Young, T. H. 2008 Effects of cyclic mechanical stretching on the mRNA expression of tendon/ligament-related and osteoblast-specific genes in human mesenchymal stem cells. Connect. Tissue Res. 49, 7-14. (doi:10.1080/03008200701818561)
    • (2008) Connect. Tissue Res. , vol.49 , pp. 7-14
    • Chen, Y.J.1    Huang, C.H.2    Lee, I.C.3    Lee, Y.T.4    Chen, M.H.5    Young, T.H.6
  • 14
    • 3042717667 scopus 로고    scopus 로고
    • Regulation of integrin-mediated cellular responses through assembly of a CAS/Crk scaffold
    • Chodniewicz, D. & Klemke, R. L. 2004 Regulation of integrin-mediated cellular responses through assembly of a CAS/Crk scaffold. Biochim. Biophys. Acta 1692, 63-76.
    • (2004) Biochim. Biophys. Acta , vol.1692 , pp. 63-76
    • Chodniewicz, D.1    Klemke, R.L.2
  • 15
    • 72449124116 scopus 로고    scopus 로고
    • Material properties of the cell dictate stress-induced spreading and differentiation in embryonic stem cells
    • doi:10.1038/nmat2563
    • Chowdhury, F., Na, S., Li, D., Poh, Y. C., Tanaka, T. S., Wang, F. & Wang, N. 2010 Material properties of the cell dictate stress-induced spreading and differentiation in embryonic stem cells. Nat. Mater. 9, 82-88. (doi:10.1038/nmat2563)
    • (2010) Nat. Mater. , vol.9 , pp. 82-88
    • Chowdhury, F.1    Na, S.2    Li, D.3    Poh, Y.C.4    Tanaka, T.S.5    Wang, F.6    Wang, N.7
  • 16
    • 33644517215 scopus 로고    scopus 로고
    • In vitro generated extracellular matrix and fluid shear stress synergistically enhance 3D osteoblastic differentiation
    • doi:10.1073/pnas.0505661103
    • Datta, N., Pham, Q. P., Sharma, U., Sikavitsas, V. I., Jansen, J. A. & Mikos, A. G. 2006 In vitro generated extracellular matrix and fluid shear stress synergistically enhance 3D osteoblastic differentiation. Proc. Natl Acad. Sci. USA 103, 2488-2493. (doi:10.1073/pnas.0505661103)
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 2488-2493
    • Datta, N.1    Pham, Q.P.2    Sharma, U.3    Sikavitsas, V.I.4    Jansen, J.A.5    Mikos, A.G.6
  • 17
    • 0029072762 scopus 로고
    • Flow-mediated endothelial mechanotransduction
    • Davies, P. F. 1995 Flow-mediated endothelial mechanotransduction. Physiol. Rev. 75, 519-560.
    • (1995) Physiol. Rev. , vol.75 , pp. 519-560
    • Davies, P.F.1
  • 18
    • 33747152561 scopus 로고    scopus 로고
    • Matrix elasticity directs stem cell lineage specification
    • doi:10.1016/j.cell.2006.06.044
    • Engler, A. J., Sen, S., Sweeney, H. L. & Discher, D. E. 2006 Matrix elasticity directs stem cell lineage specification. Cell 126, 677-689. (doi:10.1016/j.cell.2006.06.044)
    • (2006) Cell , vol.126 , pp. 677-689
    • Engler, A.J.1    Sen, S.2    Sweeney, H.L.3    Discher, D.E.4
  • 19
    • 0027523375 scopus 로고
    • Endothelial cell calcium increases during flow-induced dilation in isolated arterioles
    • Falcone, J. C., Kuo, L. & Meininger, G. A. 1993 Endothelial cell calcium increases during flow-induced dilation in isolated arterioles. Am. J. Physiol. 264, H653-H659.
    • (1993) Am. J. Physiol. , vol.264
    • Falcone, J.C.1    Kuo, L.2    Meininger, G.A.3
  • 20
    • 0033175564 scopus 로고    scopus 로고
    • Selective regulation of integrin-cytoskeleton interactions by the tyrosine kinase Src
    • doi:10.1038/12021
    • Felsenfeld, D. P., Schwartzberg, P. L., Venegas, A., Tse, R. & Sheetz, M. P. 1999 Selective regulation of integrin-cytoskeleton interactions by the tyrosine kinase Src. Nat. Cell Biol. 1, 200-206. (doi:10.1038/12021)
    • (1999) Nat. Cell Biol. , vol.1 , pp. 200-206
    • Felsenfeld, D.P.1    Schwartzberg, P.L.2    Venegas, A.3    Tse, R.4    Sheetz, M.P.5
  • 21
    • 0021972202 scopus 로고
    • Flow effects on prostacyclin production by cultured human endothelial cells
    • doi:10.1126/science.3883488
    • Frangos, J. A., Eskin, S. G., McIntire, L. V. & Ives, C. L. 1985 Flow effects on prostacyclin production by cultured human endothelial cells. Science 227, 1477-1479. (doi:10.1126/science.3883488)
    • (1985) Science , vol.227 , pp. 1477-1479
    • Frangos, J.A.1    Eskin, S.G.2    McIntire, L.V.3    Ives, C.L.4
  • 22
    • 70350400620 scopus 로고    scopus 로고
    • Force-induced cell polarisation is linked to RhoA-driven microtubule-independent focal-adhesion sliding
    • doi:10.1242/jcs.054866
    • Goldyn, A. M., Rioja, B. A., Spatz, J. P., Ballestrem, C. & Kemkemer, R. 2009 Force-induced cell polarisation is linked to RhoA-driven microtubule-independent focal-adhesion sliding. J. Cell Sci. 122, 3644-3651. (doi:10.1242/jcs.054866)
    • (2009) J. Cell Sci. , vol.122 , pp. 3644-3651
    • Goldyn, A.M.1    Rioja, B.A.2    Spatz, J.P.3    Ballestrem, C.4    Kemkemer, R.5
  • 23
    • 45449112757 scopus 로고    scopus 로고
    • Real-time monitoring of phosphodiesterase inhibition in intact cells
    • doi:10.1016/j.cellsig.2008.03.011
    • Herget, S., Lohse, M. J. & Nikolaev, V. O. 2008 Real-time monitoring of phosphodiesterase inhibition in intact cells. Cell. Signal. 20, 1423-1431. (doi:10.1016/j.cellsig.2008.03.011)
    • (2008) Cell. Signal. , vol.20 , pp. 1423-1431
    • Herget, S.1    Lohse, M.J.2    Nikolaev, V.O.3
  • 24
    • 54449083872 scopus 로고    scopus 로고
    • Haptotaxis of endothelial cell migration under flow
    • doi:10.1007/978-1-59745-571-8-15
    • Hsu, S., Thakar, R. & Li, S. 2007 Haptotaxis of endothelial cell migration under flow. Methods Mol. Med. 139, 237-250. (doi:10.1007/978-1-59745- 571-8-15)
    • (2007) Methods Mol. Med. , vol.139 , pp. 237-250
    • Hsu, S.1    Thakar, R.2    Li, S.3
  • 25
    • 34047245477 scopus 로고    scopus 로고
    • Integrin alpha v beta 3 controls activity and oncogenic potential of primed c-Src
    • doi:10.1158/0008-5472.CAN-06-3654
    • Huveneers, S., van den Bout, I., Sonneveld, P., Sancho, A., Sonnenberg, A. & Danen, E. H. 2007 Integrin alpha v beta 3 controls activity and oncogenic potential of primed c-Src. Cancer Res. 67, 2693-2700. (doi:10.1158/0008-5472.CAN-06-3654)
    • (2007) Cancer Res. , vol.67 , pp. 2693-2700
    • Huveneers, S.1    Van Den Bout, I.2    Sonneveld, P.3    Sancho, A.4    Sonnenberg, A.5    Danen, E.H.6
  • 27
    • 33744488545 scopus 로고    scopus 로고
    • Cellular mechanotransduction: Putting all the pieces together again
    • doi:10.1096/fj.05-5424rev
    • Ingber, D. E. 2006 Cellular mechanotransduction: putting all the pieces together again. FASEB J. 20, 811-827. (doi:10.1096/fj.05-5424rev)
    • (2006) FASEB J , vol.20 , pp. 811-827
    • Ingber, D.E.1
  • 28
    • 0028777967 scopus 로고
    • Aequorea green fluorescent protein. Expression of the gene and fluorescence characteristics of the recombinant protein
    • doi:10.1016/0014-5793(94)80472-9
    • Inouye, S. & Tsuji, F. I. 1994 Aequorea green fluorescent protein. Expression of the gene and fluorescence characteristics of the recombinant protein. FEBS Lett. 341, 277-280. (doi:10.1016/0014-5793(94)80472-9)
    • (1994) FEBS Lett , vol.341 , pp. 277-280
    • Inouye, S.1    Tsuji, F.I.2
  • 29
    • 0036724188 scopus 로고    scopus 로고
    • Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells
    • doi:10.1128/MCB.22.18.6582-6591.2002
    • Itoh, R. E., Kurokawa, K., Ohba, Y., Yoshizaki, H., Mochizuki, N. & Matsuda, M. 2002 Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells. Mol. Cell. Biol. 22, 6582-6591. (doi:10.1128/MCB.22.18.6582-6591.2002)
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 6582-6591
    • Itoh, R.E.1    Kurokawa, K.2    Ohba, Y.3    Yoshizaki, H.4    Mochizuki, N.5    Matsuda, M.6
  • 30
    • 33750959642 scopus 로고    scopus 로고
    • Effects of mechanical stimulation on the biomechanics and histology of stem cell-collagen sponge constructs for rabbit patellar tendon repair
    • doi:10.1089/ten. 2006.12.2291
    • Juncosa-Melvin, N., Shearn, J. T., Boivin, G. P., Gooch, C., Galloway, M. T., West, J. R., Nirmalanandhan, V. S., Bradica, G. & Butler, D. L. 2006 Effects of mechanical stimulation on the biomechanics and histology of stem cell-collagen sponge constructs for rabbit patellar tendon repair. Tissue Eng. 12, 2291-2300. (doi:10.1089/ten. 2006.12.2291)
    • (2006) Tissue Eng , vol.12 , pp. 2291-2300
    • Juncosa-Melvin, N.1    Shearn, J.T.2    Boivin, G.P.3    Gooch, C.4    Galloway, M.T.5    West, J.R.6    Nirmalanandhan, V.S.7    Bradica, G.8    Butler, D.L.9
  • 31
    • 34250902322 scopus 로고    scopus 로고
    • Mechanical stimulation increases collagen type I and collagen type III gene expression of stem cell-collagen sponge constructs for patellar tendon repair
    • doi:10.1089/ten.2006.0339
    • Juncosa-Melvin, N., Matlin, K. S., Holdcraft, R. W., Nirmalanandhan, V. S. & Butler, D. L. 2007 Mechanical stimulation increases collagen type I and collagen type III gene expression of stem cell-collagen sponge constructs for patellar tendon repair. Tissue Eng. 13, 1219-1226. (doi:10.1089/ten.2006.0339)
    • (2007) Tissue Eng. , vol.13 , pp. 1219-1226
    • Juncosa-Melvin, N.1    Matlin, K.S.2    Holdcraft, R.W.3    Nirmalanandhan, V.S.4    Butler, D.L.5
  • 32
    • 1842530398 scopus 로고    scopus 로고
    • Integrins in mechanotransduction
    • doi:10.1074/jbc.R300038200
    • Katsumi, A., Orr, A. W., Tzima, E. & Schwartz, M. A. 2004 Integrins in mechanotransduction. J. Biol. Chem. 279, 12 001-12 004. (doi:10.1074/jbc. R300038200)
    • (2004) J. Biol. Chem. , vol.279 , pp. 12001-12004
    • Katsumi, A.1    Orr, A.W.2    Tzima, E.3    Schwartz, M.A.4
  • 33
    • 0031002460 scopus 로고    scopus 로고
    • Folding-unfolding transitions in single titin molecules characterized with laser tweezers
    • doi:10.1126/science.276.5315.1112
    • Kellermayer, M. S., Smith, S. B., Granzier, H. L. & Bustamante, C. 1997 Folding-unfolding transitions in single titin molecules characterized with laser tweezers. Science 276, 1112-1116. (doi:10.1126/science.276.5315.1112)
    • (1997) Science , vol.276 , pp. 1112-1116
    • Kellermayer, M.S.1    Smith, S.B.2    Granzier, H.L.3    Bustamante, C.4
  • 35
    • 70849127367 scopus 로고    scopus 로고
    • Fibronectin forms the most extensible biological fibers displaying switchable force-exposed cryptic binding sites
    • doi:10.1073/pnas.0907518106
    • Klotzsch, E., Smith, M. L., Kubow, K. E., Muntwyler, S., Little, W. C., Beyeler, F., Gourdon, D., Nelson, B. J. & Vogel, V. 2009 Fibronectin forms the most extensible biological fibers displaying switchable force-exposed cryptic binding sites. Proc. Natl Acad. Sci. USA 106, 18 267-18 272. (doi:10.1073/pnas.0907518106)
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 18267-18272
    • Klotzsch, E.1    Smith, M.L.2    Kubow, K.E.3    Muntwyler, S.4    Little, W.C.5    Beyeler, F.6    Gourdon, D.7    Nelson, B.J.8    Vogel, V.9
  • 36
    • 20144373766 scopus 로고    scopus 로고
    • Non-viral gene delivery regulated by stiffness of cell adhesion substrates
    • doi:10.1038/nmat1392
    • Kong, H. J., Liu, J., Riddle, K., Matsumoto, T., Leach, K. & Mooney, D. J. 2005a Non-viral gene delivery regulated by stiffness of cell adhesion substrates. Nat. Mater. 4, 460-464. (doi:10.1038/nmat1392)
    • (2005) Nat. Mater. , vol.4 , pp. 460-464
    • Kong, H.J.1    Liu, J.2    Riddle, K.3    Matsumoto, T.4    Leach, K.5    Mooney, D.J.6
  • 37
    • 15444367409 scopus 로고    scopus 로고
    • FRET measurements of cell-traction forces and nano-scale clustering of adhesion ligands varied by substrate stiffness
    • doi:10.1073/pnas.0405873102
    • Kong, H. J., Polte, T. R., Alsberg, E. & Mooney, D. J. 2005b FRET measurements of cell-traction forces and nano-scale clustering of adhesion ligands varied by substrate stiffness. Proc. Natl Acad. Sci. USA 102, 4300-4305. (doi:10.1073/pnas.0405873102)
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 4300-4305
    • Kong, H.J.1    Polte, T.R.2    Alsberg, E.3    Mooney, D.J.4
  • 38
    • 0034644603 scopus 로고    scopus 로고
    • Localized Rac activation dynamics visualized in living cells
    • doi:10.1126/science.290.5490.333
    • Kraynov, V. S., Chamberlain, C., Bokoch, G. M., Schwartz, M. A., Slabaugh, S. & Hahn, K. M. 2000 Localized Rac activation dynamics visualized in living cells. Science 290, 333-337. (doi:10.1126/science.290.5490.333)
    • (2000) Science , vol.290 , pp. 333-337
    • Kraynov, V.S.1    Chamberlain, C.2    Bokoch, G.M.3    Schwartz, M.A.4    Slabaugh, S.5    Hahn, K.M.6
  • 39
    • 0028095848 scopus 로고
    • Role of calcium and calmodulin in flow-induced nitric oxide production in endothelial cells
    • Kuchan, M. J. & Frangos, J. A. 1994 Role of calcium and calmodulin in flow-induced nitric oxide production in endothelial cells. Am. J. Physiol. 266, C628-C636.
    • (1994) Am. J. Physiol. , vol.266
    • Kuchan, M.J.1    Frangos, J.A.2
  • 40
    • 33750838708 scopus 로고    scopus 로고
    • Anisotropic mechanosensing by mesenchymal stem cells
    • doi:10.1073/pnas.0604182103
    • Kurpinski, K., Chu, J., Hashi, C. & Li, S. 2006 Anisotropic mechanosensing by mesenchymal stem cells. Proc. Natl Acad. Sci. USA 103, 16 095-16 100. (doi:10.1073/pnas.0604182103)
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 16095-16100
    • Kurpinski, K.1    Chu, J.2    Hashi, C.3    Li, S.4
  • 41
    • 34347212520 scopus 로고    scopus 로고
    • Effects of uniaxial cyclic strain on adipose-derived stem cell morphology, proliferation, and differentiation
    • doi:10.1007/s10237-006-0053-y
    • Lee, W. C., Maul, T. M., Vorp, D. A., Rubin, J. P. & Marra, K. G. 2007 Effects of uniaxial cyclic strain on adipose-derived stem cell morphology, proliferation, and differentiation. Biomech. Model. Mechanobiol. 6, 265-273. (doi:10.1007/s10237-006-0053-y)
    • (2007) Biomech. Model. Mechanobiol. , vol.6 , pp. 265-273
    • Lee, W.C.1    Maul, T.M.2    Vorp, D.A.3    Rubin, J.P.4    Marra, K.G.5
  • 42
    • 0030729489 scopus 로고    scopus 로고
    • Fluid shear stress activation of focal adhesion kinase. Linking to mitogen-activated protein kinases
    • doi:10.1074/jbc.272.48.30455
    • Li, S., Kim, M., Hu, Y. L., Jalali, S., Schlaepfer, D. D., Hunter, T., Chien, S. & Shyy, J. Y. 1997 Fluid shear stress activation of focal adhesion kinase. Linking to mitogen-activated protein kinases. J. Biol. Chem. 272, 30 455-30 462. (doi:10.1074/jbc.272.48.30455)
    • (1997) J. Biol. Chem. , vol.272 , pp. 30455-30462
    • Li, S.1    Kim, M.2    Hu, Y.L.3    Jalali, S.4    Schlaepfer, D.D.5    Hunter, T.6    Chien, S.7    Shyy, J.Y.8
  • 43
    • 45049084735 scopus 로고    scopus 로고
    • Assay to mechanically tune and optically probe fibrillar fibronectin conformations from fully relaxed to breakage
    • doi:10.1016/j.matbio.2008.02.003
    • Little, W. C., Smith, M. L., Ebneter, U. & Vogel, V. 2008 Assay to mechanically tune and optically probe fibrillar fibronectin conformations from fully relaxed to breakage. Matrix Biol. 27, 451-461. (doi:10.1016/j.matbio.2008. 02.003)
    • (2008) Matrix Biol. , vol.27 , pp. 451-461
    • Little, W.C.1    Smith, M.L.2    Ebneter, U.3    Vogel, V.4
  • 44
    • 0031865351 scopus 로고    scopus 로고
    • Bcl-2 and Bax interactions in mitochondria probed with green fluorescent protein and fluorescence resonance energy transfer
    • doi:10.1038/nbt0698-547
    • Mahajan, N. P., Linder, K., Berry, G., Gordon, G. W., Heim, R. & Herman, B. 1998 Bcl-2 and Bax interactions in mitochondria probed with green fluorescent protein and fluorescence resonance energy transfer. Nat. Biotechnol. 16, 547-552. (doi:10.1038/nbt0698-547)
    • (1998) Nat. Biotechnol. , vol.16 , pp. 547-552
    • Mahajan, N.P.1    Linder, K.2    Berry, G.3    Gordon, G.W.4    Heim, R.5    Herman, B.6
  • 45
    • 0031017220 scopus 로고    scopus 로고
    • Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure
    • doi:10.1073/pnas.94.3.849
    • Maniotis, A. J., Chen, C. S. & Ingber, D. E. 1997 Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure. Proc. Natl Acad. Sci. USA 94, 849-854. (doi:10.1073/pnas.94.3.849)
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 849-854
    • Maniotis, A.J.1    Chen, C.S.2    Ingber, D.E.3
  • 46
    • 3042853029 scopus 로고    scopus 로고
    • Mechanosensitive ion channels: Molecules of mechanotransduction
    • doi:10.1242/jcs.01232
    • Martinac, B. 2004 Mechanosensitive ion channels: molecules of mechanotransduction. J. Cell Sci. 117, 2449-2460. (doi:10.1242/jcs.01232)
    • (2004) J. Cell Sci. , vol.117 , pp. 2449-2460
    • Martinac, B.1
  • 48
    • 44349176807 scopus 로고    scopus 로고
    • A fluorescence energy transfer-based mechanical stress sensor for specific proteins in situ
    • doi:10.1111/j.1742-4658.2008.06461.x
    • Meng, F., Suchyna, T. M. & Sachs, F. 2008 A fluorescence energy transfer-based mechanical stress sensor for specific proteins in situ. FEBS J. 275, 3072-3087. (doi:10.1111/j.1742-4658.2008.06461.x)
    • (2008) FEBS J. , vol.275 , pp. 3072-3087
    • Meng, F.1    Suchyna, T.M.2    Sachs, F.3
  • 49
    • 33748286819 scopus 로고    scopus 로고
    • Integrin-regulated FAK-Src signaling in normal and cancer cells
    • doi:10.1016/j.ceb.2006.08.011
    • Mitra, S. K. & Schlaepfer, D. D. 2006 Integrin-regulated FAK-Src signaling in normal and cancer cells. Curr. Opin. Cell Biol. 18, 516-523. (doi:10.1016/j.ceb.2006.08.011)
    • (2006) Curr. Opin. Cell Biol. , vol.18 , pp. 516-523
    • Mitra, S.K.1    Schlaepfer, D.D.2
  • 50
    • 11244258882 scopus 로고    scopus 로고
    • Focal adhesion kinase: In command and control of cell motility
    • doi:10.1038/nrm1549
    • Mitra, S. K., Hanson, D. A. & Schlaepfer, D. D. 2005 Focal adhesion kinase: in command and control of cell motility. Nat. Rev. Mol. Cell Biol. 6, 56-68. (doi:10.1038/nrm1549)
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 56-68
    • Mitra, S.K.1    Hanson, D.A.2    Schlaepfer, D.D.3
  • 52
    • 55749086825 scopus 로고    scopus 로고
    • Application of fluorescence resonance energy transfer and magnetic twisting cytometry to quantify mechanochemical signaling activities in a living cell
    • doi:10.1126/scisignal.134pl1
    • Na, S. & Wang, N. 2008 Application of fluorescence resonance energy transfer and magnetic twisting cytometry to quantify mechanochemical signaling activities in a living cell. Sci. Signal. 1, p.l1. (doi:10.1126/scisignal. 134pl1)
    • (2008) Sci. Signal. , vol.1 , pp. 11
    • Na, S.1    Wang, N.2
  • 53
    • 44349189707 scopus 로고    scopus 로고
    • Rapid signal transduction in living cells is a unique feature of mechanotransduction
    • doi:10.1073/pnas.0711704105
    • Na, S., Collin, O., Chowdhury, F., Tay, B., Ouyang, M., Wang, Y. & Wang, N. 2008 Rapid signal transduction in living cells is a unique feature of mechanotransduction. Proc. Natl Acad. Sci. USA 105, 6626-6631. (doi:10.1073/pnas.0711704105)
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 6626-6631
    • Na, S.1    Collin, O.2    Chowdhury, F.3    Tay, B.4    Ouyang, M.5    Wang, Y.6    Wang, N.7
  • 54
    • 21444436724 scopus 로고    scopus 로고
    • Evolutionary optimization of fluorescent proteins for intracellular FRET
    • doi:10.1038/nbt1066
    • Nguyen, A. W. & Daugherty, P. S. 2005 Evolutionary optimization of fluorescent proteins for intracellular FRET. Nat. Biotechnol. 23, 355-360. (doi:10.1038/nbt1066)
    • (2005) Nat. Biotechnol. , vol.23 , pp. 355-360
    • Nguyen, A.W.1    Daugherty, P.S.2
  • 55
    • 33644855566 scopus 로고    scopus 로고
    • Functional TRPM7 channels accumulate at the plasma membrane in response to fluid flow
    • doi:10.1161/01.RES.0000200179.29375.cc
    • Oancea, E., Wolfe, J. T. & Clapham, D. E. 2006 Functional TRPM7 channels accumulate at the plasma membrane in response to fluid flow. Circ. Res. 98, 245-253. (doi:10.1161/01.RES.0000200179.29375.cc)
    • (2006) Circ. Res. , vol.98 , pp. 245-253
    • Oancea, E.1    Wolfe, J.T.2    Clapham, D.E.3
  • 56
    • 58649097753 scopus 로고    scopus 로고
    • Fluid shear stress induces arterial differentiation of endothelial progenitor cells
    • doi:10.1152/japplphysiol.00197.2008
    • Obi, S., Yamamoto, K., Shimizu, N., Kumagaya, S., Masumura, T., Sokabe, T., Asahara, T. & Ando, J. 2009 Fluid shear stress induces arterial differentiation of endothelial progenitor cells. J. Appl. Physiol. 106, 203-211. (doi:10.1152/japplphysiol.00197.2008)
    • (2009) J. Appl. Physiol. , vol.106 , pp. 203-211
    • Obi, S.1    Yamamoto, K.2    Shimizu, N.3    Kumagaya, S.4    Masumura, T.5    Sokabe, T.6    Asahara, T.7    Ando, J.8
  • 57
    • 0029847806 scopus 로고    scopus 로고
    • Crystal structure of the Aequorea victoria green fluorescent protein
    • doi:10.1126/science.273.5280.1392
    • Ormo, M., Cubitt, A. B., Kallio, K., Gross, L. A., Tsien, R. Y. & Remington, S. J. 1996 Crystal structure of the Aequorea victoria green fluorescent protein. Science 273, 1392-1395. (doi:10.1126/science.273.5280.1392)
    • (1996) Science , vol.273 , pp. 1392-1395
    • Ormo, M.1    Cubitt, A.B.2    Kallio, K.3    Gross, L.A.4    Tsien, R.Y.5    Remington, S.J.6
  • 58
    • 47749090496 scopus 로고    scopus 로고
    • Visualization of polarized membrane type 1 matrix metalloproteinase activity in live cells by fluorescence resonance energy transfer imaging
    • doi:10.1074/jbc.M709872200
    • Ouyang, M., Lu, S., Li, X. Y., Xu, J., Seong, J., Giepmans, B. N., Shyy, J. Y., Weiss, S. J. & Wang, Y. 2008a Visualization of polarized membrane type 1 matrix metalloproteinase activity in live cells by fluorescence resonance energy transfer imaging. J. Biol. Chem. 283, 17 740-17 748. (doi:10.1074/jbc.M709872200)
    • (2008) J. Biol. Chem. , vol.283 , pp. 17740-17748
    • Ouyang, M.1    Lu, S.2    Li, X.Y.3    Xu, J.4    Seong, J.5    Giepmans, B.N.6    Shyy, J.Y.7    Weiss, S.J.8    Wang, Y.9
  • 59
    • 55749093427 scopus 로고    scopus 로고
    • Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors
    • doi:10.1073/pnas.0807537105
    • Ouyang, M., Sun, J., Chien, S. & Wang, Y. 2008b Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors. Proc. Natl Acad. Sci. USA 105, 14 353-14 358. (doi:10.1073/pnas. 0807537105)
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 14353-14358
    • Ouyang, M.1    Sun, J.2    Chien, S.3    Wang, Y.4
  • 60
    • 34347230164 scopus 로고    scopus 로고
    • Measuring calcium signaling using genetically targetable fluorescent indicators
    • doi:10.1038/nprot.2006.172
    • Palmer, A. E. & Tsien, R. Y. 2006 Measuring calcium signaling using genetically targetable fluorescent indicators. Nat. Protoc. 1, 1057-1065. (doi:10.1038/nprot.2006.172)
    • (2006) Nat. Protoc. , vol.1 , pp. 1057-1065
    • Palmer, A.E.1    Tsien, R.Y.2
  • 61
    • 70449133423 scopus 로고    scopus 로고
    • The effect of matrix stiffness on mesenchymal stem cell differentiation in a 3D thixotropic gel
    • doi:10.1016/j.biomaterials.2009.09.057
    • Pek, Y. S., Wan, A. C. & Ying, J. Y. 2010 The effect of matrix stiffness on mesenchymal stem cell differentiation in a 3D thixotropic gel. Biomaterials 31, 385-391. (doi:10.1016/j.biomaterials.2009.09.057)
    • (2010) Biomaterials , vol.31 , pp. 385-391
    • Pek, Y.S.1    Wan, A.C.2    Ying, J.Y.3
  • 62
    • 60149091370 scopus 로고    scopus 로고
    • Cyclic compression maintains viability and induces chondrogenesis of human mesenchymal stem cells in fibrin gel scaffolds
    • doi:10.1089/scd. 2008.0030
    • Pelaez, D., Huang, C. Y. & Cheung, H. S. 2008 Cyclic compression maintains viability and induces chondrogenesis of human mesenchymal stem cells in fibrin gel scaffolds. Stem Cells Dev. 18, 93-102. (doi:10.1089/scd. 2008.0030)
    • (2008) Stem Cells Dev. , vol.18 , pp. 93-102
    • Pelaez, D.1    Huang, C.Y.2    Cheung, H.S.3
  • 63
    • 33646197411 scopus 로고    scopus 로고
    • Spatiotemporal dynamics of RhoA activity in migrating cells
    • doi:10.1038/nature04665
    • Pertz, O., Hodgson, L., Klemke, R. L. & Hahn, K. M. 2006 Spatiotemporal dynamics of RhoA activity in migrating cells. Nature 440, 1069-1072. (doi:10.1038/nature04665)
    • (2006) Nature , vol.440 , pp. 1069-1072
    • Pertz, O.1    Hodgson, L.2    Klemke, R.L.3    Hahn, K.M.4
  • 64
    • 70849098229 scopus 로고    scopus 로고
    • Rapid activation of Rac GTPase in living cells by force is independent of Src
    • doi:10.1371/journal.pone.0007886
    • Poh, Y. C., Na, S., Chowdhury, F., Ouyang, M., Wang, Y. & Wang, N. 2009 Rapid activation of Rac GTPase in living cells by force is independent of Src. PLoS ONE 4, e7886. (doi:10.1371/journal.pone.0007886)
    • (2009) PLoS ONE , vol.4
    • Poh, Y.C.1    Na, S.2    Chowdhury, F.3    Ouyang, M.4    Wang, Y.5    Wang, N.6
  • 65
    • 34248513296 scopus 로고    scopus 로고
    • Participation of caveolae in beta1 integrin-mediated mechanotransduction
    • doi:10.1016/j.bbrc.2007.04.179
    • Radel, C., Carlile-Klusacek, M. & Rizzo, V. 2007 Participation of caveolae in beta1 integrin-mediated mechanotransduction. Biochem. Biophys. Res. Commun. 358, 626-631. (doi:10.1016/j.bbrc.2007.04.179)
    • (2007) Biochem. Biophys. Res. Commun. , vol.358 , pp. 626-631
    • Radel, C.1    Carlile-Klusacek, M.2    Rizzo, V.3
  • 66
    • 0031011418 scopus 로고    scopus 로고
    • Detection in living cells of Ca2 + -dependent changes in the fluorescence emission of an indicator composed of two green fluorescent protein variants linked by a calmodulin-binding sequence. A new class of fluorescent indicators
    • doi:10.1074/jbc.272.20.13270
    • Romoser, V. A., Hinkle, P. M. & Persechini, A. 1997 Detection in living cells of Ca2 + -dependent changes in the fluorescence emission of an indicator composed of two green fluorescent protein variants linked by a calmodulin-binding sequence. A new class of fluorescent indicators. J. Biol. Chem. 272, 13 270-13 274. (doi:10.1074/jbc.272.20.13270)
    • (1997) J. Biol. Chem. , vol.272 , pp. 13270-13274
    • Romoser, V.A.1    Hinkle, P.M.2    Persechini, A.3
  • 67
    • 0022516979 scopus 로고
    • Flow-induced release of endothelium-derived relaxing factor
    • Rubanyi, G. M., Romero, J. C. & Vanhoutte, P. M. 1986 Flow-induced release of endothelium-derived relaxing factor. Am. J. Physiol. 250, H1145-H1149.
    • (1986) Am. J. Physiol. , vol.250
    • Rubanyi, G.M.1    Romero, J.C.2    Vanhoutte, P.M.3
  • 68
    • 56249113001 scopus 로고    scopus 로고
    • Emergence of patterned stem cell differentiation within multicellular structures
    • doi:10.1634/stemcells.2008-0432
    • Ruiz, S. A. & Chen, C. S. 2008 Emergence of patterned stem cell differentiation within multicellular structures. Stem Cells 26, 2921-2927. (doi:10.1634/stemcells.2008-0432)
    • (2008) Stem Cells , vol.26 , pp. 2921-2927
    • Ruiz, S.A.1    Chen, C.S.2
  • 69
    • 58849160148 scopus 로고    scopus 로고
    • Visualization of Src activity at different compartments of the plasma membrane by FRET imaging
    • doi:10.1016/j.chembiol.2008.11.007
    • Seong, J., Lu, S., Ouyang, M., Huang, H., Zhang, J., Frame, M. C. & Wang, Y. 2009 Visualization of Src activity at different compartments of the plasma membrane by FRET imaging. Chem. Biol. 16, 48-57. (doi:10.1016/j.chembiol. 2008.11.007)
    • (2009) Chem. Biol. , vol.16 , pp. 48-57
    • Seong, J.1    Lu, S.2    Ouyang, M.3    Huang, H.4    Zhang, J.5    Frame, M.C.6    Wang, Y.7
  • 70
    • 11144267737 scopus 로고    scopus 로고
    • Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein
    • doi:10.1038/nbt1037
    • Shaner, N. C., Campbell, R. E., Steinbach, P. A., Giepmans, B. N., Palmer, A. E. & Tsien, R. Y. 2004 Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat. Biotechnol. 22, 1567-1572. (doi:10.1038/nbt1037)
    • (2004) Nat. Biotechnol. , vol.22 , pp. 1567-1572
    • Shaner, N.C.1    Campbell, R.E.2    Steinbach, P.A.3    Giepmans, B.N.4    Palmer, A.E.5    Tsien, R.Y.6
  • 71
    • 30944467113 scopus 로고    scopus 로고
    • A guide to choosing fluorescent proteins
    • doi:10.1038/nmeth819
    • Shaner, N. C., Steinbach, P. A. & Tsien, R. Y. 2005 A guide to choosing fluorescent proteins. Nat. Methods 2, 905-909. (doi:10.1038/nmeth819)
    • (2005) Nat. Methods , vol.2 , pp. 905-909
    • Shaner, N.C.1    Steinbach, P.A.2    Tsien, R.Y.3
  • 72
    • 34548363677 scopus 로고    scopus 로고
    • Bright far-red fluorescent protein for whole-body imaging
    • doi:10.1038/nmeth1083
    • Shcherbo, D. et al. 2007 Bright far-red fluorescent protein for whole-body imaging. Nat. Methods 4, 741-746. (doi:10.1038/nmeth1083)
    • (2007) Nat. Methods , vol.4 , pp. 741-746
    • Shcherbo, D.1
  • 73
    • 34548576414 scopus 로고
    • Extraction, purification and properties of aequorin, a bioluminescent protein from the luminous hydromedusan, Aequorea
    • doi:10.1002/jcp.1030590302
    • Shimomura, O., Johnson, F. H. & Saiga, Y. 1962 Extraction, purification and properties of aequorin, a bioluminescent protein from the luminous hydromedusan, Aequorea. J. Cell. Comp. Physiol. 59, 223-239. (doi:10.1002/jcp.1030590302)
    • (1962) J. Cell. Comp. Physiol. , vol.59 , pp. 223-239
    • Shimomura, O.1    Johnson, F.H.2    Saiga, Y.3
  • 75
    • 33845918633 scopus 로고    scopus 로고
    • Osteogenic differentiation of human mesenchymal stem cells in collagen matrices: Effect of uniaxial cyclic tensile strain on bone morphogenetic protein (BMP-2) mRNA expression
    • doi:10.1089/ten.2006.12.3459
    • Sumanasinghe, R. D., Bernacki, S. H. & Loboa, E. G. 2006 Osteogenic differentiation of human mesenchymal stem cells in collagen matrices: effect of uniaxial cyclic tensile strain on bone morphogenetic protein (BMP-2) mRNA expression. Tissue Eng. 12, 3459-3465. (doi:10.1089/ten.2006.12.3459)
    • (2006) Tissue Eng. , vol.12 , pp. 3459-3465
    • Sumanasinghe, R.D.1    Bernacki, S.H.2    Loboa, E.G.3
  • 76
    • 34347244955 scopus 로고    scopus 로고
    • Magnetic tweezers in cell biology
    • doi:10.1016/S0091-679X(07)83020-2
    • Tanase, M., Biais, N. & Sheetz, M. 2007 Magnetic tweezers in cell biology. Methods Cell Biol. 83, 473-493. (doi:10.1016/S0091-679X(07)83020-2)
    • (2007) Methods Cell Biol. , vol.83 , pp. 473-493
    • Tanase, M.1    Biais, N.2    Sheetz, M.3
  • 77
    • 26444501596 scopus 로고    scopus 로고
    • Kinetics of the endocytotic pathway of low density lipoprotein (LDL) in human endothelial cell line under shear stress: An in vitro confocal microscopy study
    • Traore, M., Sun, R. J., Fawzi-Grancher, S., Dumas, D., Qing, X., Santus, R., Stoltz, J. F. & Muller, S. 2005 Kinetics of the endocytotic pathway of low density lipoprotein (LDL) in human endothelial cell line under shear stress: an in vitro confocal microscopy study. Clin. Hemorheol. Microcirc. 33, 243-251.
    • (2005) Clin. Hemorheol. Microcirc. , vol.33 , pp. 243-251
    • Traore, M.1    Sun, R.J.2    Fawzi-Grancher, S.3    Dumas, D.4    Qing, X.5    Santus, R.6    Stoltz, J.F.7    Muller, S.8
  • 78
    • 0031663369 scopus 로고    scopus 로고
    • The green fluorescent protein
    • doi:10.1146/annurev.biochem.67.1.509
    • Tsien, R. Y. 1998 The green fluorescent protein. Annu. Rev. Biochem. 67, 509-544. (doi:10.1146/annurev.biochem.67.1.509)
    • (1998) Annu. Rev. Biochem. , vol.67 , pp. 509-544
    • Tsien, R.Y.1
  • 79
    • 33644866797 scopus 로고    scopus 로고
    • Role of small GTPases in endothelial cytoskeletal dynamics and the shear stress response
    • doi:10.1161/01.RES.0000200162.94463.d7
    • Tzima, E. 2006 Role of small GTPases in endothelial cytoskeletal dynamics and the shear stress response. Circ. Res. 98, 176-185. (doi:10.1161/01.RES. 0000200162.94463.d7)
    • (2006) Circ. Res. , vol.98 , pp. 176-185
    • Tzima, E.1
  • 80
    • 0035801529 scopus 로고    scopus 로고
    • Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment
    • doi:10.1093/emboj/20.17.4639
    • Tzima, E., Del Pozo, M. A., Shattil, S. J., Chien, S. & Schwartz, M. A. 2001 Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment. EMBO J. 20, 4639-4647. (doi:10.1093/emboj/20.17.4639)
    • (2001) EMBO J. , vol.20 , pp. 4639-4647
    • Tzima, E.1    Del Pozo, M.A.2    Shattil, S.J.3    Chien, S.4    Schwartz, M.A.5
  • 81
    • 0037121966 scopus 로고    scopus 로고
    • Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression
    • doi:10.1093/emboj/cdf688
    • Tzima, E., Del Pozo, M. A., Kiosses, W. B., Mohamed, S. A., Li, S., Chien, S. & Schwartz, M. A. 2002 Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression. EMBO J. 21, 6791-6800. (doi:10.1093/emboj/cdf688)
    • (2002) EMBO J. , vol.21 , pp. 6791-6800
    • Tzima, E.1    Del Pozo, M.A.2    Kiosses, W.B.3    Mohamed, S.A.4    Li, S.5    Chien, S.6    Schwartz, M.A.7
  • 83
    • 43249121576 scopus 로고    scopus 로고
    • Hydrostatic pressure enhances chondrogenic differentiation of human bone marrow stromal cells in osteochondrogenic medium
    • doi:10.1007/s10439-008-9448-5
    • Wagner, D. R., Lindsey, D. P., Li, K. W., Tummala, P., Chandran, S. E., Smith, R. L., Longaker, M. T., Carter, D. R. & Beaupre, G. S. 2008 Hydrostatic pressure enhances chondrogenic differentiation of human bone marrow stromal cells in osteochondrogenic medium. Ann. Biomed. Eng. 36, 813-820. (doi:10.1007/s10439-008-9448-5)
    • (2008) Ann. Biomed. Eng. , vol.36 , pp. 813-820
    • Wagner, D.R.1    Lindsey, D.P.2    Li, K.W.3    Tummala, P.4    Chandran, S.E.5    Smith, R.L.6    Longaker, M.T.7    Carter, D.R.8    Beaupre, G.S.9
  • 84
    • 0027172919 scopus 로고
    • Mechanotransduction across the cell surface and through the cytoskeleton
    • doi:10.1126/science.7684161
    • Wang, N., Butler, J. P. & Ingber, D. E. 1993 Mechanotransduction across the cell surface and through the cytoskeleton. Science 260, 1124-1127. (doi:10.1126/science.7684161)
    • (1993) Science , vol.260 , pp. 1124-1127
    • Wang, N.1    Butler, J.P.2    Ingber, D.E.3
  • 86
    • 17844388845 scopus 로고    scopus 로고
    • Visualizing the mechanical activation of Src
    • doi:10.1038/nature03469
    • Wang, Y., Botvinick, E. L., Zhao, Y., Berns, M.W., Usami, S., Tsien, R. Y. & Chien, S. 2005 Visualizing the mechanical activation of Src. Nature 434, 1040-1045. (doi:10.1038/nature03469)
    • (2005) Nature , vol.434 , pp. 1040-1045
    • Wang, Y.1    Botvinick, E.L.2    Zhao, Y.3    Berns, M.W.4    Usami, S.5    Tsien, R.Y.6    Chien, S.7
  • 87
    • 33746326465 scopus 로고    scopus 로고
    • Shear stress protects against endothelial regulation of vascular smooth muscle cell migration in a coculture system
    • doi:10.1080/10623320600760282
    • Wang, H. Q., Huang, L. X., Qu, M. J., Yan, Z. Q., Liu, B., Shen, B. R. & Jiang, Z. L. 2006 Shear stress protects against endothelial regulation of vascular smooth muscle cell migration in a coculture system. Endothelium 13, 171-180. (doi:10.1080/10623320600760282)
    • (2006) Endothelium , vol.13 , pp. 171-180
    • Wang, H.Q.1    Huang, L.X.2    Qu, M.J.3    Yan, Z.Q.4    Liu, B.5    Shen, B.R.6    Jiang, Z.L.7
  • 88
    • 34547405865 scopus 로고    scopus 로고
    • Selective adapter recruitment and differential signaling networks by VEGF vs. shear stress
    • doi:10.1073/pnas.0703088104
    • Wang, Y., Chang, J., Chen, K. D., Li, S., Li, J. Y., Wu, C. & Chien, S. 2007 Selective adapter recruitment and differential signaling networks by VEGF vs. shear stress. Proc. Natl Acad. Sci. USA 104, 8875-8879. (doi:10.1073/pnas.0703088104)
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 8875-8879
    • Wang, Y.1    Chang, J.2    Chen, K.D.3    Li, S.4    Li, J.Y.5    Wu, C.6    Chien, S.7
  • 89
    • 50249098131 scopus 로고    scopus 로고
    • Fluorescence proteins, live-cell imaging, and mechanobiology: Seeing is believing
    • doi:10.1146/annurev.bioeng.010308.161731
    • Wang, Y., Shyy, J. Y. & Chien, S. 2008 Fluorescence proteins, live-cell imaging, and mechanobiology: seeing is believing. Annu. Rev. Biomed. Eng. 10, 1-38. (doi:10.1146/annurev.bioeng.010308.161731)
    • (2008) Annu. Rev. Biomed. Eng. , vol.10 , pp. 1-38
    • Wang, Y.1    Shyy, J.Y.2    Chien, S.3
  • 90
    • 15544374098 scopus 로고    scopus 로고
    • Intracellular calcium release and cardiac disease
    • doi:10.1146/annurev.physiol.67. 040403.114521
    • Wehrens, X. H., Lehnart, S. E. & Marks, A. R. 2005 Intracellular calcium release and cardiac disease. Annu. Rev. Physiol. 67, 69-98. (doi:10.1146/annurev.physiol.67. 040403.114521)
    • (2005) Annu. Rev. Physiol. , vol.67 , pp. 69-98
    • Wehrens, X.H.1    Lehnart, S.E.2    Marks, A.R.3
  • 91
    • 0037731922 scopus 로고    scopus 로고
    • Shear stress-induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinases
    • doi:10.1083/jcb.200210135
    • Wojciak-Stothard, B. & Ridley, A. J. 2003 Shear stress-induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinases. J. Cell Biol. 161, 429-439. (doi:10.1083/jcb.200210135)
    • (2003) J. Cell Biol. , vol.161 , pp. 429-439
    • Wojciak-Stothard, B.1    Ridley, A.J.2
  • 92
    • 0034283214 scopus 로고    scopus 로고
    • Fluid shear stress activates Ca(2+) influx into human endothelial cells via P2X4 purinoceptors
    • Yamamoto, K., Korenaga, R., Kamiya, A. & Ando, J. 2000 Fluid shear stress activates Ca(2+) influx into human endothelial cells via P2X4 purinoceptors. Circ. Res. 87, 385-391.
    • (2000) Circ. Res. , vol.87 , pp. 385-391
    • Yamamoto, K.1    Korenaga, R.2    Kamiya, A.3    Ando, J.4
  • 93
    • 20144385079 scopus 로고    scopus 로고
    • Fluid shear stress induces differentiation of Flk-1-positive embryonic stem cells into vascular endothelial cells in vitro
    • doi:10.1152/ajpheart.00956.2004
    • Yamamoto, K. et al. 2005 Fluid shear stress induces differentiation of Flk-1-positive embryonic stem cells into vascular endothelial cells in vitro. Am. J. Physiol. Heart Circ. Physiol. 288, H1915-H1924. (doi:10.1152/ajpheart. 00956.2004)
    • (2005) Am. J. Physiol. Heart Circ. Physiol. , vol.288
    • Yamamoto, K.1
  • 94
    • 0042672950 scopus 로고    scopus 로고
    • Activity of Rho-family GTPases during cell division as visualized with FRET-based probes
    • doi:10.1083/jcb.200212049
    • Yoshizaki, H., Ohba, Y., Kurokawa, K., Itoh, R. E., Nakamura, T., Mochizuki, N., Nagashima, K. & Matsuda, M. 2003 Activity of Rho-family GTPases during cell division as visualized with FRET-based probes. J. Cell Biol. 162, 223-232. (doi:10.1083/jcb.200212049)
    • (2003) J. Cell Biol. , vol.162 , pp. 223-232
    • Yoshizaki, H.1    Ohba, Y.2    Kurokawa, K.3    Itoh, R.E.4    Nakamura, T.5    Mochizuki, N.6    Nagashima, K.7    Matsuda, M.8
  • 95
    • 26244434925 scopus 로고    scopus 로고
    • Polarized down-regulation of the paxillin-p130CAS-Rac1 pathway induced by shear flow
    • doi:10.1242/jcs.02523
    • Zaidel-Bar, R., Kam, Z. & Geiger, B. 2005 Polarized down-regulation of the paxillin-p130CAS-Rac1 pathway induced by shear flow. J. Cell Sci. 118, 3997-4007. (doi:10.1242/jcs.02523)
    • (2005) J. Cell Sci. , vol.118 , pp. 3997-4007
    • Zaidel-Bar, R.1    Kam, Z.2    Geiger, B.3
  • 96
    • 0036902813 scopus 로고    scopus 로고
    • Creating new fluorescent prsobes for cell biology
    • doi:10.1038/nrm976
    • Zhang, J., Campbell, R. E., Ting, A. Y. & Tsien, R. Y. 2002 Creating new fluorescent prsobes for cell biology. Nat. Rev. Mol. Cell Biol. 3, 906-918. (doi:10.1038/nrm976)
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 906-918
    • Zhang, J.1    Campbell, R.E.2    Ting, A.Y.3    Tsien, R.Y.4
  • 97
    • 66749151000 scopus 로고    scopus 로고
    • Mechanical stimulus alters conformation of type 1 parathyroid hormone receptor in bone cells
    • doi:10.1152/ajpcell.00549.2008
    • Zhang, Y. L., Frangos, J. A. & Chachisvilis, M. 2009 Mechanical stimulus alters conformation of type 1 parathyroid hormone receptor in bone cells. Am. J. Physiol. Cell Physiol. 296, C1 391-C1 399. (doi:10.1152/ajpcell. 00549.2008)
    • (2009) Am. J. Physiol. Cell Physiol. , vol.296
    • Zhang, Y.L.1    Frangos, J.A.2    Chachisvilis, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.