Negative inotropy by angiotensin II is mediated via phosphoinositide 3-kinase alpha-protein kinase C-coupled signaling pathway

Hypertension

Volumn 56, Issue 3, 2010, Pages 349-350

  Dhingra, Rimpy ^a   Kirshenbaum, Lorrie A ^a,b  

^a ST BONIFACE GENERAL HOSPITAL   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; CALCIUM CHANNEL L TYPE; GLYCOGEN SYNTHASE KINASE 3BETA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE ALPHA; PROTEIN KINASE C; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBUNIT; EXCITATION CONTRACTION COUPLING; HEART HYPERTROPHY; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; MOUSE; NONHUMAN; NOTE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANGIOTENSIN II; ANIMALS; MICE; MYOCARDIAL CONTRACTION; PROTEIN KINASE C; SIGNAL TRANSDUCTION;

EID: 77955943196     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.110.156158     Document Type: Note

References (11)

1. Sopjani M, Kunert A, Czarkowski K, Klaus F, Laufer J, Foller M, Lang F. Regulation of the Ca(2 +) channel TRPV6 by the kinases SGK1, PKB/Akt, and PIKfyve. J Membr Biol. 2010;233:35-41.
2. Gusev K, Domenighetti AA, Delbridge LM, Pedrazzini T, Niggli E, Egger M. angiotensiniotensin II-mediated adaptive and maladaptive remodeling of cardiomyocyte excitation-contraction coupling. Circ Res. 2009;105:42-50.
3. Kamp TJ, Hell JW. Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C. Circ Res. 2000;87:1095-1102.
4. Liu F, Carlos LD, Ferreira RA, Rocha J, Ferro MC, Tourrette A, Quignard F, Robitzer M. Synthesis, texture, and photoluminescence of lanthanide- containing chitosan-silica hybrids. J Phys Chem B. 2010;114:77-83.
5. Matsui T, Nagoshi T, Rosenzweig A. Akt and PI 3-kinase signaling in cardiomyocyte hypertrophy and survival. Cell Cycle. 2003;2:220-223.
6. Quignard J, Feletou M, Corriu C, Chataigneau T, Edwards G, Weston AH, Vanhoutte PM. 3-Morpholinosydnonimine (SIN-1) and K(+) channels in smooth muscle cells of the rabbit and guinea pig carotid arteries. Eur J Pharmacol. 2000;399:9-16.
7. Quignard JF, Mironneau J, Carricaburu V, Fournier B, Babich A, Nurnberg B, Mironneau C, Macrez N. Phosphoinositide 3-kinase gamma mediates angiotensin II-induced stimulation of L-type calcium channels in vascular myocytes. J Biol Chem. 2001;276:32545-32551.
8. Brilla CG, Rupp H. Myocardial collagen matrix remodeling and congestive heart failure. Cardiologia. 1994;39:389-393.
9. Dean RG, Bach LA, Burrell LM. Upregulation of cardiac insulin-like growth factor-I receptor by ACE inhibition after myocardial infarction: potential role in remodeling. J Histochem Cytochem. 2003;51:831-839.
10. Chintalgattu V, Katwa LC. Role of protein kinase C-delta in angiotensin II induced cardiac fibrosis. Biochem Biophys Res Commun. 2009;386:612-616.
11. Liang W, Oudit GY, Patel MM, Shah AM, Woodgett JR, Tsushima RG, Ward ME, Backx PH. Role of phosphoinositide 3-kinase alpha, protein kinase C, and L-type calcium channels in mediating the complex actions of angiotensin II on mouse cardiac contractility. Hypertension. 2010;56:422-429.