Racial variation in medical outcomes among living kidney donors

New England Journal of Medicine

Volumn 363, Issue 8, 2010, Pages 724-732

  Lentine, Krista L ^a   Schnitzler, Mark A ^a   Xiao, Huiling ^a   Saab, Georges ^b   Salvalaggio, Paolo R ^c   Axelrod, David ^d   Davis, Connie L ^c   Abbott, Kevin C ^e   Brennan, Daniel C ^b  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

^e WALTER REED ARMY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGINA PECTORIS; ARTICLE; CARDIOVASCULAR RISK; CHRONIC KIDNEY DISEASE; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DEMOGRAPHY; DIABETES MELLITUS; ETHNIC DIFFERENCE; FEMALE; GRAFT RECIPIENT; HAZARD RATIO; HEALTH SURVEY; HEART INFARCTION; HISPANIC; HUMAN; HYPERTENSION; KIDNEY DONOR; KIDNEY FAILURE; LIVING DONOR; MAJOR CLINICAL STUDY; MALE; NEGRO; NEPHRECTOMY; PREVALENCE; PRIORITY JOURNAL; PRIVATE HEALTH INSURANCE; RACE DIFFERENCE; RETROSPECTIVE STUDY; SOCIAL STATUS; STROKE; TREATMENT OUTCOME; UNITED STATES;

EID: 77955913153     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa1000950     Document Type: Article

References (40)

1. Terasaki PI, Cecka JM, Gjertson DW, Takemoto S. High survival rates of kidney transplants from spousal and living unrelated donors. N Engl J Med 1995;333:333-6.
2. Horvat LD, Shariff SZ, Garg AX. Global trends in the rates of living kidney donation. Kidney Int 2009;75:1088-98.
3. Organ Procurement and Transplant Network database. (Accessed July 23, 2010, at http://www.optn.org/data/.)
4. Ommen ES, Winston JA, Murphy B. Medical risks in living kidney donors: absence of proof is not proof of absence. Clin J Am Soc Nephrol 2006;1:885-95.
5. Ibrahim HN, Foley R, Tan L, et al. Long-term consequences of kidney donation. N Engl J Med 2009;360:459-69.
6. Segev DL, Muzaale AD, Caffo BS, et al. Perioperative mortality and long-term survival following live kidney donation. JAMA 2010;303:959-66.
7. Carter JS, Pugh JA, Monterrosa A. Non-insulin-dependent diabetes mellitus in minorities in the United States. Ann Intern Med 1996;125:221-32. (Pubitemid 126449266)
8. Cutler JA, Sorlie PD, Wolz M, Thom T, Fields LE, Roccella EJ. Trends in hypertension prevalence, awareness, treatment, and control rates in United States adults between 1988-1994 and 1999-2004. Hypertension 2008;52:818-27.
9. Cowie CC, Port FK, Wolfe RA, Savage PJ, Moll PP, Hawthorne VM. Disparities in incidence of diabetic end-stage renal disease according to race and type of diabetes. N Engl J Med 1989;321:1074-9.
10. Brancati FL, Whittle JC, Whelton PK, Seidler AJ, Klag MJ. The excess incidence of diabetic end-stage renal disease among blacks: a population-based study of potential explanatory factors. JAMA 1992;268:3079-84.
11. Brown RS Jr, Higgins R, Pruett TL. The evolution and direction of OPTN oversight of live organ donation and transplantation in the United States. Am J Transplant 2009;9:31-4.
12. Graham W. Living donor follow-up data: status report from the OPTN. Presentations: November 13, 2008. Rockville, MD: Advisory Committee on Organ Transplantation (ACOT). (Accessed July 23, 2010, at https://www.team-psa.com/ DOT/ACOT2008/presentations.asp.)
13. Mandelbrot D, Pavlakis M, Karp SJ, et al. Practices and barriers in long-term living kidney donor follow-up: a survey of U.S. transplant centers. Transplantation 2009;88:855-60.
14. Organ Procurement and Transplant Network. About OPTN data. (Accessed July 23, 2010, at http://optn.transplant.hrsa.gov/data/about/.)
15. Hebert PL, Geiss LS, Tierney EF, Engelgau MM, Yawn BP, McBean AM. Identifying persons with diabetes using Medicare claims data. Am J Med Qual 1999;14:270-7.
16. Kasiske BL, Snyder JJ, Gilbertson D, Matas AJ. Diabetes mellitus after kidney transplantation in the United States. Am J Transplant 2003;3:178-85.
17. Stevens LA, Fares G, Fleming J, et al. Low rates of testing and diagnostic codes usage in a commercial clinical laboratory: evidence for lack of physician awareness of chronic kidney disease. J Am Soc Nephrol 2005;16:2439-48.
18. Methods appendix. In: U.S. Renal Data System. USRDS 2008 annual data report, Bethesda, MD: National Institute of Diabetes and Digestive and Kidney Diseases, 2008. (Accessed July 23, 2010, at http://www.usrds.org/2008/pdf/V2- Appendices-2008.pdf.)
19. Lentine KL, Schnitzler MA, Abbott KC, Bramesfeld K, Buchanan PM, Brennan DC. Sensitivity of billing claims for cardiovascular disease events among kidney transplant recipients. Clin J Am Soc Nephrol 2009;4:1213-21.
20. Agency for Healthcare Research and Quality. Creating and validating an index of socioeconomic status. (Accessed July 23, 2010, at http://www.ahrq.gov/ qual/medicareindicators/medicareindicators3.htm.)
21. Centers for Disease Control and Prevention. National Health and Nutrition Examination Survey: questionnaires, datasets and related documentation. (Accessed July 23, 2010, at http://www.cdc.gov/nchs/nhanes/nhanes2005-2006/ nhanes05-06.htm.)
22. Delmonico F. A report of the Amsterdam Forum on the Care of the Live Kidney Donor: data and medical guidelines. Transplantation 2005;79:Suppl:S53- S66. (Pubitemid 40446548)
23. Textor SC, Taler SJ, Driscoll N, et al. Blood pressure and renal function after kidney donation from hypertensive living donors. Transplantation 2004;78:276-82.
24. Boudville N, Prasad GV, Knoll G, et al. Meta-analysis: risk for hypertension in living kidney donors. Ann Intern Med 2006;145:185-96.
25. Garg AX, Prasad GV, Thiessen-Philbrook HR, et al. Cardiovascular disease and hypertension risk in living kidney donors: an analysis of health administrative data in Ontario, Canada. Transplantation 2008;86:399-406.
26. Nogueira JM, Weir MR, Jacobs S, et al. A study of renal outcomes in African American living kidney donors. Transplantation 2009;88:1371-6.
27. Haffner SM, Mitchell BD, Stern MP, Hazuda HP, Patterson JK. Decreased prevalence of hypertension in Mexican-Americans. Hypertension 1990;16:225-34.
28. Ramírez EA. Cardiovascular health in Puerto Ricans compared to other population groups in the United States. Ethn Dis 1991;1:188-99.
29. Mitchell BD, Stern MP, Haffner SM, Hazuda HP, Patterson JK. Risk factors for cardiovascular mortality in Mexican Americans and non-Hispanic whites: San Antonio Heart Study. Am J Epidemiol 1990;131:423-33.
30. Pappas G, Gergen PJ, Carroll M. Hypertension prevalence and the status of awareness, treatment, and control in the Hispanic Health and Nutrition Examination Survey (HHANES), 1982-84. Am J Public Health 1990;80:1431-6.
31. Storsley LJ, Young A, Rush DN, et al. Long-term medical outcomes among aboriginal living kidney donors. Transplantation 2010 June 18 [Epub ahead of print].
32. Incidence and prevalence. In: U.S. Renal Data System. USRDS 2008 annual data report. Bethesda, MD: National Institute of Diabetes and Digestive and Kidney Diseases, 2008. (Accessed July 23, 2010, at http://www.usrds.org/adr.htm. )
33. Gibney EM, King AL, Maluf DG, Garg AX, Parikh CR. Living kidney donors requiring transplantation: focus on African Americans. Transplantation 2007;84:647-9.
34. Cherikh WS, Fan PY, Taranto SE, Randall HB, Young CJ. Prior living kidney donors who were subsequently placed on the waiting list: an updated OPTN analysis. Am J Transplant 2008;8:Suppl:2:335. abstract.
35. Ommen ES, Gill JS. The system of health insurance for living organ donors is a disincentive for live donation. Am J Transplant 2010;10:747-50.
36. Wainright JL, Cooper M, Bolton DL, Davis CL. The changing landscape of living kidney donors in the US. Am J Transplant 2009;9:Suppl 2:310-1. abstract.
37. Herring AA, Woolhandler S, Himmelstein DU. Insurance status of U.S. organ donors and transplant recipients: the uninsured give, but rarely receive. Int J Health Serv 2008;38:641-52.
38. Young CJ, Gaston RS. Renal transplantation in black Americans. N Engl J Med 2000;343:1545-52.
39. Gore JL, Danovitch GM, Litwin MS, Pham PT, Singer JS. Disparities in the utilization of live donor renal transplantation. Am J Transplant 2009;9:1124-33.
40. Reeves-Daniel A, Adams PL, Daniel K, et al. Impact of race and gender on live kidney donation. Clin Transplant 2009;23:39-46.