Identification and quantitative analysis of acetaminophen, acetylsalicylic acid, and caffeine in commercial analgesic tablets by LC-MS

Journal of Chemical Education

Volumn 87, Issue 8, 2010, Pages 838-841

  Fenk, Christopher J ^a   Hickman, Nicole M ^a   Fincke, Melissa A ^a   Douglas H Motry, ^a   Barry Lavine, ^b  

^a KENT STATE UNIVERSITY   (United States)

^b OKLAHOMA STATE UNIVERSITY   (United States)

Author keywords

Analytical chemistry; Chromatography; Drugs Pharmaceuticals; First year undergraduate general; Hands on learning manipulativesinquiry based discovery learning; HPLC; Instrumental Methods; Laboratory instruction; Mass Spectrometry; Organic chemistry; Second year undergraduate; Separation science; Spectroscopy; Upper division undergraduate; UV Vis spectroscopy

Indexed keywords

EID: 77955909606     PISSN: 00219584     EISSN: None     Source Type: Journal    
DOI: 10.1021/ed100280y     Document Type: Article

References (20)

1. Sojka, Z.; Chi, M. J. Chem. Educ. 2008, 85, 934-940.
2. Anzivino, B.; Tilley, L. J.; Ingalls, L. R.; Hall, A. B.; Drugan, J. E. J. Chem. Educ. 2009, 86, 55-59.
3. Lavoie, J. M.; Chornet, E.; Pelletier, A. J. Chem. Educ. 2008, 85, 1555-1557.
4. Wang, Y. M.; Ocariz, J.; Hammersand, J.; MacDonald, E.; Bartczak, A.; Kero, F.; Young, V. Y.; Williams, K. R. J. Chem. Educ. 2008, 85, 957-958.
5. Latimer, D. J. Chem. Educ. 2007, 84, 699-701.
6. Stock, N. L.; Martin, J. W.; Yun, Y.; Mabury, S. A. J. Chem. Educ. 2007, 84, 310-311.
7. Arnquist, I. J.; Beussman, D. J. J. Chem. Educ. 2009, 86, 382-384.
8. Arnquist, I. J.; Beussman, D. J. J. Chem. Educ. 2007, 84, 1971-1973.
9. Weinecke, A.; Ryzhov, V. J. Chem. Educ. 2005, 82, 99-102.
10. Stynes,H.C.; Layo,A.; Smith, R.W. J. Chem. Educ. 2004, 81, 266-269.
11. Reimann, C. T.; Mie, A.; Nilsson, C. J. Chem. Educ. 2005, 82, 1215-1218.
12. Coe, B. J. J. Chem. Educ. 2004, 81, 718-721.
13. Bergen, H. R.; Benson, L. M.; Naylor, S. J. Chem. Educ. 2000, 77, 1325-1326.
14. Sproch, N.; Begin, K. J.; Morris, R. J. J. Chem. Educ. 1996, 73, A33-A39.
15. Haddad, P.;Hutchins, S.;Tuffy,M. J. Chem. Educ. 1983, 60, 166-168.
16. Beaver, R. W.; Bunch, J. E.; Jones, L. A. J. Chem. Educ. 1983, 60, 1000-1001.
17. Ferguson, G. K. J. Chem. Educ. 1998, 75, 467-469.
18. Kagel, R. A.; Farwell, S. O. J. Chem. Educ. 1983, 60, 163-166.
19. National Institute of Standards and Technology (NIST) Web-Book. http://webbook.nist.gov (accessed May 2010).
20. Spectra Data Base System for Organic Compounds. http://www. aist.go.jp (accessed May 2010).