Aggregating and disaggregating patients in clinical trials and their subgroup analyses

Annals of Internal Medicine

Volumn 153, Issue 1, 2010, Pages 51-52

  Kent, David M ^a   Lindenauer, Peter K ^b  

^a TUFTS MEDICAL CENTER   (United States)

^b BAYSTATE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENOXAPARIN; ANTICOAGULANT AGENT;

BLEEDING; EDITORIAL; HIGH RISK PATIENT; PRIORITY JOURNAL; RISK FACTOR; TREATMENT DURATION; VENOUS THROMBOEMBOLISM; ACUTE DISEASE; DELAYED RELEASE FORMULATION; HUMAN; NOTE; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; STANDARD; STATISTICAL ANALYSIS; WALKING DIFFICULTY;

ACUTE DISEASE; ANTICOAGULANTS; DATA INTERPRETATION, STATISTICAL; DELAYED-ACTION PREPARATIONS; ENOXAPARIN; HUMANS; MOBILITY LIMITATION; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RISK ASSESSMENT; VENOUS THROMBOEMBOLISM;

EID: 77955909163     PISSN: 00034819     EISSN: 15393704     Source Type: Journal    
DOI: 10.7326/0003-4819-153-1-201007060-00012     Document Type: Editorial

References (6)

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4. Kent DM, Hayward RA. Limitations of applying summary results of clinical trials to individual patients: the need for risk stratification. JAMA. 2007;298:1209-12. [PMID: 17848656]
5. Sun X, Briel M, Walter SD, Guyatt GH. Is a subgroup effect believable? Updating criteria to evaluate the credibility of subgroup analyses. BMJ. 2010;340:c117. [PMID: 20354011]
6. Rothberg MB, Lahti M, Pekow PS, Lindenauer PK. Venous thromboembolism prophylaxis among medical patients at US hospitals. J Gen Intern Med. 2010;25:489-94. [PMID: 20352366]