Strategies for recognition of stem-loop RNA structures by synthetic ligands: Application to the HIV-1 frameshift stimulatory sequence

Journal of Medicinal Chemistry

Volumn 53, Issue 16, 2010, Pages 6018-6027

  Palde, Prakash B ^b   Ofori, Leslie O ^a   Gareiss, Peter C ^b   Lerea, Jaclyn ^a   Miller, Benjamin L ^a,b  

^a UNIVERSITY OF ROCHESTER   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 ETHYL 3 CARBOXYQUINOLINE DERIVATIVE; 2 ETHYLQUINOLINE 3 CARBOXAMIDE; 2 ETHYLQUINOLINE 3 CARBOXYLIC ACID; ALKENE; AMIDE; CARBOXYLIC ACID DERIVATIVE; DISULFIDE; GAG PROTEIN; MITOMYCIN C; NEOMYCIN; POL PROTEIN; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING KINETICS; CONTROLLED STUDY; CYTOTOXICITY; DNA SEQUENCE; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; RIBOSOMAL FRAMESHIFTING; RNA BINDING; RNA SEQUENCE; RNA STRUCTURE; STRUCTURE ACTIVITY RELATION; SURFACE PLASMON RESONANCE;

ALKENES; ANTI-HIV AGENTS; BASE SEQUENCE; CELL SURVIVAL; CELLS, CULTURED; DISULFIDES; FIBROBLASTS; FRAMESHIFTING, RIBOSOMAL; HIV-1; HUMANS; LIGANDS; MUTATION; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; OLIGOPEPTIDES; QUINOLINES; RNA, VIRAL; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77955904335     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm100231t     Document Type: Article

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