Pupillary autonomic dysfunction in multiple system atrophy and Parkinson's disease: An assessment by eye-drop tests

Clinical Autonomic Research

Volumn 20, Issue 3, 2010, Pages 191-197

  Yamashita, Fumitada ^a   Hirayama, M ^a   Nakamura, T ^a   Takamori, M ^b   Hori, N ^a   Uchida, K ^a   Hama, T ^a   Sobue, Gen ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SHIZUOKA SAISEIKAI GENERAL HOSPITAL   (Japan)

Author keywords

Eye drop test; Multiple system atrophy(MSA); Parkinson's disease (PD); Pupil assay; Pupillary autonomic dysfunction

Indexed keywords

(3 IODOBENZYL)GUANIDINE I 123; DIPIVEFRINE; EYE DROPS; NORADRENALIN; PILOCARPINE; (3 IODOBENZYL)GUANIDINE; DIAGNOSTIC AGENT; MIOTIC AGENT; RADIOPHARMACEUTICAL AGENT;

ADULT; ARTICLE; AUTONOMIC DYSFUNCTION; CLINICAL ASSESSMENT; CONTROLLED STUDY; DISEASE COURSE; DISEASE DURATION; DISEASE SEVERITY; FEMALE; HEAD TILTING; HEART; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDIASTINUM; ORTHOSTATIC HYPOTENSION; PARKINSON DISEASE; PUPIL; PUPILLARY AUTONOMIC DYSFUNCTION; SCINTIGRAPHY; SHY DRAGER SYNDROME; SYSTOLIC BLOOD PRESSURE; AGED; AUTONOMIC NERVOUS SYSTEM; AUTONOMIC NEUROPATHY; BLOOD PRESSURE; HEART FUNCTION TEST; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; PUPIL REFLEX; RECEIVER OPERATING CHARACTERISTIC; SCINTISCANNING;

3-IODOBENZYLGUANIDINE; AGED; AUTONOMIC NERVOUS SYSTEM; AUTONOMIC NERVOUS SYSTEM DISEASES; BLOOD PRESSURE; DISEASE PROGRESSION; FEMALE; HEART FUNCTION TESTS; HUMANS; MALE; MIDDLE AGED; MIOTICS; MULTIPLE SYSTEM ATROPHY; PARKINSON DISEASE; PILOCARPINE; PUPIL; RADIOPHARMACEUTICALS; REFLEX, PUPILLARY; ROC CURVE;

EID: 77955903032     PISSN: 09599851     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10286-009-0051-0     Document Type: Article

References (26)

1. Wenning GK, Colosimo C, Geser F, Poewe W (2004) Multiple system atrophy. Lancet Neurol 3:93-103
2. Gilman S, Low PA, Quinn N et al (1999) Consensus statement on the diagnosis of multiple system atrophy. J Neurol Sci 163:94-98 (Pubitemid 29155424)
3. Daniel SE (1999) The neuropathology and neurochemistry of multiple system atrophy. In: Mathias CJ, Bannister SR (eds) Autonomic failure. Oxford University Press, Oxford, pp 321-328
4. Wenning GK, Tison F, Ben Shomo Y et al (1997) Multiple system atrophy: a review of 203 pathologically proven cases. Mov Disord 12:133-147
5. Gray F, Vincent D, Hauw JJ (1988) Quantitative study of lateral horn cells in 15 cases of multiple system atrophy. Acta Neuropathol 75:513-518
6. Oppenheimer DR (1980) Lateral horn cells in progressive autonomic failure. J Neurol Sci 46:393-404
7. Riley DE, Chelimsky TC (2003) Autonomic nervous system testing may not distinguish multiple system atrophy from Parkinson's disease. J Neurol Neurosurg Psychiatry 74:56-60
8. Hori N, Takamori M, Fumitada Y, Hirayama M et al (2008) Pupillary supersensitivity and visual disturbance in Parkinson's disease. Clin Auton Res 18:20-27
9. Nirankari VS et al (1982) Ocular manifestations of Shy-Drager syndrome. Ann Ophthalmol 14:635-638
10. Daniel SE, Lees AJ (1993) The clinical features of Parkinson's disease in 100 histologically proven cases. Adv Neurol 60:595-599
11. Ishikawa S (2001) Normal data on pupillary dynamics. Neuroophthalmol Jpn 18:154-156
12. Shirley A, Smith SA, Smith SE (1999) Pupil function: tests and disorders. In: Bannister R, Mathias CJ (eds) Autonomic failure. A textbook of clinical disorders of the autonomic nervous system, 4th edn. Oxford University Press, Oxford, pp 245-253
13. Mathias CJ, Bannister R (1999) Investigation of autonomic disorders. Autonomic failure. In: Mathias CJ, Bannister R (eds) Autonomic failure. A textbook of clinical disorders of the autonomic nervous system, 4th edn. Oxford University Press, Oxford, pp 171-175
14. Polinsky R, Kopin I, Ebert M, Weise V (1981) Pharmacologic distinction of different orthostatic hypotension syndromes. Neurology 31:1-7
15. Niimi Y, Ieda T, Hirayama M, Koike Y, Sobue G, Hasegawa Y, Takahashi A (1999) Clinical and physiologic characteristics of autonomic failure with Parkinson's disease. Clin Auton Res 9:139-144 (Pubitemid 29493493)
16. Hamada K, Hirayama M, Watanabe H, Kobayashi R, Ito H, Ieda T, Koike Y, Sobue G (2003) Onset age and severity of motor impairment are associated with reduction of myocardial 123I-MIBG uptake in Parkinson's disease. J Neurol Neurosurg Psychiatry 74:423-426
17. Jacobson DM (1990) Pupillary responses to dilute pilocarpine in preganglionic 3rd nerve disorders. Neurology 40:804-808
18. Sugiyama T, Utsumi T (1990) Pupillary dynamics in Parkinson's disease. Neuro-ophthalmology 10:1-7
19. Sawada H, Yamakawa K, Yamakado H, Hosokawa R, Ohba M, Miyamoto K, Kawamura T, Shimohama S (2005) Cocaine and phenylephrine eye drop test for Parkinson disease. JAMA 293:932-934
20. Spokes EGS, Bannister R, Oppenheimer DR (1979) Multiple system atrophy with autonomic failure. Clinical, histological and neurochemical observations in four cases. J Neurol Sci 43:59-82
21. Matthews MR (1999) Autonomic ganglia and preganglionic neurons in autonomic failure. In: Bannister R, Mathias CJ (eds) Autonomic failure. A textbook of clinical disorders of the autonomic nervous system, 4th edn. Oxford University Press, Oxford, pp 329-339
22. Khurana RK (1994) Cholinergic dysfunction in Shy-Drager syndrome: effect of the parasympathomimetic agent, bethanechol. Clin Auton Res 4:5-13
23. Shy GM, Drager GA (1960) A neurological syndrome associated with orthostatic hypotension: a clinicopathological study. Arch Neural 2:511-527
24. Orimo S et al (2007) Degeneration of cardiac sympathetic nerve can occur in multiple system atrophy. Acta Neuropathol 113:81-86
25. Wenning GK, Ben Shomo Y, Hughes A, Daniel SE, Lees A, Quinn NP (2000) What clinical features are most useful to distinguish definite multiple system atrophy from Parkinson's disease. J Neurol Neurosurg Psychiatry 68:434-440
26. Osaki Y, Wenning GK, Daniel SE et al (2002) Do published criteria improve clinical diagnostic accuracy in multiple system atrophy? Neurology 59:1486-1491