Synthesis, spectroscopic studies and biological activity of a novel nucleopeptide with Moloney murine leukemia virus reverse transcriptase inhibitory activity

Amino Acids

Volumn 38, Issue 5, 2010, Pages 1489-1496

  Roviello, Giovanni N ^a   Di Gaetano, Sonia ^a   Capasso, Domenica ^b   Cesarani, Annalisa ^a   Bucci, Enrico M ^a   Pedone, Carlo ^b  

^a CNR   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

PNA; Reverse transcriptase; RNA; Virus

Indexed keywords

ALPHA,EPSILON LYSINE PEPTIDE NUCLEIC ACID; MESSENGER RNA; NUCLEOTIDE; OLIGOMER; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG; PEPTIDE; PRIMER DNA;

ANTIVIRAL ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CIRCULAR DICHROISM; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG STABILITY; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; ENZYME ASSAY; ENZYME INHIBITION; HELA CELL; HUMAN; IN VITRO STUDY; MOLONEY LEUKEMIA ONCOVIRUS; OLIGOMERIZATION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLID PHASE SYNTHESIS; ULTRAVIOLET SPECTROSCOPY; AGAR GEL ELECTROPHORESIS; CHEMISTRY; ENZYMOLOGY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NUCLEOTIDE SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYNTHESIS; ULTRAVIOLET SPECTROPHOTOMETRY;

EUKARYOTA; MOLONEY MURINE LEUKEMIA VIRUS;

BASE SEQUENCE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; DNA PRIMERS; ELECTROPHORESIS, AGAR GEL; HELA CELLS; HUMANS; MOLONEY MURINE LEUKEMIA VIRUS; PEPTIDES; REVERSE TRANSCRIPTASE INHIBITORS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 77955898177     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00726-009-0361-5     Document Type: Article

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