Update in acute pancreatitis

Current Gastroenterology Reports

Volumn 12, Issue 2, 2010, Pages 83-90

  Wu, Bechien U ^a   Conwell, Darwin L ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Acinar cell; Acute pancreatitis; Clinical management; Complications; Update

Indexed keywords

ANTIBIOTIC AGENT; DICLOFENAC; GLYCERYL TRINITRATE; INTERLEUKIN 10; NITROGEN; PANCREATIC ELASTASE; PROBIOTIC AGENT; PROTEINASE INHIBITOR; SOMATOSTATIN; UREA;

ACINAR CELL; ACUTE PANCREATITIS; ALCOHOL ABSTINENCE; APACHE; BEDSIDE INDEX OF SEVERITY IN ACUTE PANCREATITIS; CELL FATE; CELL PH; CHOLECYSTECTOMY; DEBRIDEMENT; DIABETES MELLITUS; DIET SUPPLEMENTATION; DISEASE SEVERITY; EARLY DIAGNOSIS; ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY; ENDOSCOPIC THERAPY; GALLSTONE; HARMLESS ACUTE PANCREATITIS SCORE; HEALTH CENTER; HUMAN; INFECTION; INNATE IMMUNITY; MICROENVIRONMENT; MORTALITY; MULTIPLE ORGAN FAILURE; NONHUMAN; PANCREAS EXOCRINE INSUFFICIENCY; PANCREAS NECROSIS; PANCREATITIS; PARENTERAL NUTRITION; PATHOPHYSIOLOGY; PERCUTANEOUS DRAINAGE; QUALITY OF LIFE; RANSON SCORE; REVIEW; SCORING SYSTEM; SIGNAL TRANSDUCTION; UREA NITROGEN BLOOD LEVEL; COMPUTER ASSISTED TOMOGRAPHY; DIGESTIVE TRACT ENDOSCOPY; ENTERIC FEEDING; HEALTH; MORBIDITY; NUCLEAR MAGNETIC RESONANCE IMAGING; PANCREAS RESECTION; PANCREATITIS, ACUTE NECROTIZING; PROCEDURES; SURVIVAL RATE; TRENDS;

BLOOD UREA NITROGEN; DEBRIDEMENT; ENDOSCOPY, DIGESTIVE SYSTEM; ENTERAL NUTRITION; HUMANS; MAGNETIC RESONANCE IMAGING; MORBIDITY; PANCREATECTOMY; PANCREATITIS, ACUTE NECROTIZING; SURVIVAL RATE; TOMOGRAPHY, X-RAY COMPUTED; WORLD HEALTH; GLOBAL HEALTH;

EID: 77955885730     PISSN: 15228037     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11894-010-0091-6     Document Type: Review

References (48)

1. Everhart JE, Ruhl CE: Burden of digestive diseases in the United States part III: liver, biliary tract, and pancreas. Gastroenterology 2009, 136:1134-1144. This article provides an update on the etiology of pancreatitis in the United States using several national health surveys.
2. PJ Fagenholz CF Castillo NS Harris, et al. 2007 Increasing United States hospital admissions for acute pancreatitis, 1988-2003 Ann Epidemiol 17 491 497 10.1016/j.annepidem.2007.02.002 17448682
3. Fagenholz PJ, Fernandez-del Castillo C, Harris NS, et al.: Direct medical costs of acute pancreatitis hospitalizations in the United States. Pancreas 2007, 35:302-307.
4. Bhoomagoud M, Jung T, Atladottir J, et al.: Reducing extracellular pH sensitizes the acinar cell to secretagogue-induced pancreatitis responses in rats. Gastroenterology 2009, 137:1083-1092. This study presents a compelling series of in vitro and in vivo experiments in caereulin-induced pancreatitis models that indicate the importance of extracellular pH on sensitization of acinar cells.
5. MD Noble J Romac SR Vigna RA Liddle 2008 A pH-sensitive, neurogenic pathway mediates disease severity in a model of post-ERCP pancreatitis Gut 57 1566 1571 10.1136/gut.2008.148551 1:CAS:528:DC%2BD1cXhtl2gtr%2FN 18625695
6. He S, Wang L, Miao L, et al: Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell 2009, 137:1100-1111. This study presents a compelling series of experiments that demonstrate the central role of RIP3 kinase in mediating necrosis as a pathway for cell death.
7. DW Zhang J Shao J Lin, et al. 2009 RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis Science 325 332 336 10.1126/science.1172308 1:CAS:528:DC%2BD1MXos1Sqt7Y%3D 19498109
8. R Sharif R Dawra K Wasiluk, et al. 2009 Impact of toll-like receptor 4 on the severity of acute pancreatitis and pancreatitis-associated lung injury in mice Gut 58 813 819 10.1136/gut.2008.170423 1:CAS:528:DC%2BD1MXmvFantr8%3D 19201771
9. DA Harrison G D'Amico M Singer 2007 The Pancreatitis Outcome Prediction (POP) Score: a new prognostic index for patients with severe acute pancreatitis Crit Care Med 35 1703 1708 10.1097/01.CCM.0000269031.13283.C8 17522578
10. PA Banks ML Freeman 2006 Practice guidelines in acute pancreatitis Am J Gastroenterol 101 2379 2400 10.1111/j.1572-0241.2006.00856.x 17032204
11. CE Forsmark J Baillie 2007 AGA Institute technical review on acute pancreatitis Gastroenterology 132 2022 2044 10.1053/j.gastro.2007.03.065 1:CAS:528:DC%2BD2sXmsVymsb0%3D 17484894
12. BU Wu RS Johannes X Sun, et al. 2008 The early prediction of mortality in acute pancreatitis: a large population-based study Gut 57 1698 1703 10.1136/gut.2008.152702 1:CAS:528:DC%2BD1cXhsFCrsrnO 18519429
13. VK Singh BU Wu TL Bollen, et al. 2009 A prospective evaluation of the bedside index for severity in acute pancreatitis score in assessing mortality and intermediate markers of severity in acute pancreatitis Am J Gastroenterol 104 966 971 10.1038/ajg.2009.28 19293787
14. Wu BU, Johannes RS, Sun X, et al.: Early changes in blood urea nitrogen predict mortality in acute pancreatitis. Gastroenterology 2009, 137:129-135. This large, retrospective cohort study identified an early rise (first 24 hours) in BUN as the most accurate routine laboratory test for identification of patients at increased risk of mortality from acute pancreatiits.
15. BU Wu RS Johannes DL Conwell PA Banks 2009 Early hemoconcentration predicts increased mortality only among transferred patients with acute pancreatitis Pancreatology 9 639 643 10.1159/000181175 19657219
16. Lankisch PG, Weber-Dany B, Hebel K, et al.: The harmless acute pancreatitis score: a clinical algorithm for rapid initial stratification of nonsevere disease. Clin Gastroenterol Hepatol 2009, 7:702-705; quiz 607.
17. Dellinger EP, Tellado JM, Soto NE, et al: Early antibiotic treatment for severe acute necrotizing pancreatitis: a randomized, double-blind, placebo-controlled study. Ann Surg 2007, 245:674-683. This double-blind, randomized, controlled trial demonstrated no reduction in infectious complications or mortality associated with use of prophlactic antibiotics for severe acute pancreatitis.
18. R Isenmann M Runzi M Kron, et al. 2004 Prophylactic antibiotic treatment in patients with predicted severe acute pancreatitis: a placebo-controlled, double-blind trial Gastroenterology 126 997 1004 10.1053/j.gastro.2003.12.050 1:CAS:528:DC%2BD2cXkt1Krsbg%3D 15057739
19. Besselink MG, van Santvoort HC, Boermeester MA, et al.: Timing and impact of infections in acute pancreatitis. Br J Surg 2009, 96:267-273. This large cohort study presents rich and detailed information on the incidence and impact of both intra- and extrapancreatic infection in acute pancreatitis.
20. BU Wu RS Johannes S Kurtz PA Banks 2008 The impact of hospital-acquired infection on outcome in acute pancreatitis Gastroenterology 135 816 820 10.1053/j.gastro.2008.05.053 18616944
21. SS Vege TB Gardner ST Chari, et al. 2009 Outcomes of intra-abdominal fungal vs. bacterial infections in severe acute pancreatitis Am J Gastroenterol 104 2065 2070 10.1038/ajg.2009.280 19491825
22. KJ Mortele J Girshman D Szejnfeld, et al. 2009 CT-guided percutaneous catheter drainage of acute necrotizing pancreatitis: clinical experience and observations in patients with sterile and infected necrosis AJR Am J Roentgenol 192 110 116 10.2214/AJR.08.1116 19098188
23. Seifert H, Biermer M, Schmitt W, et al.: Transluminal endoscopic necrosectomy after acute pancreatitis: a multicenter study with long-term follow-up (the GEPARD study). Gut 2009, 58:1260-1266. This study presents one of the largest case series to date that describes the experience with endoscopic necrosectomy of postnecrotic fluid collections from acute pancreatitis.
24. JJ Telford JJ Farrell JR Saltzman, et al. 2002 Pancreatic stent placement for duct disruption Gastrointest Endosc 56 18 24 10.1067/mge.2002.125107 12085030
25. C Lawrence DA Howell AM Stefan, et al. 2008 Disconnected pancreatic tail syndrome: potential for endoscopic therapy and results of long-term follow-up Gastrointest Endosc 67 673 679 10.1016/j.gie.2007.07.017 18054008
26. DL Williams T Ha C Li, et al. 2003 Modulation of tissue Toll-like receptor 2 and 4 during the early phases of polymicrobial sepsis correlates with mortality Crit Care Med 31 1808 1818 10.1097/01.CCM.0000069343.27691.F3 12794424
27. JC Alves-Filho A de Freitas M Russo FQ Cunha 2006 Toll-like receptor 4 signaling leads to neutrophil migration impairment in polymicrobial sepsis Crit Care Med 34 461 470 10.1097/01.CCM.0000198527.71819.E1 1:CAS:528: DC%2BD28Xls1Ggug%3D%3D 16424729
28. MG Besselink HC van Santvoort E Buskens, et al. 2008 Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial Lancet 371 651 659 10.1016/S0140-6736(08)60207-X 18279948
29. PE Marik GP Zaloga 2004 Meta-analysis of parenteral nutrition versus enteral nutrition in patients with acute pancreatitis BMJ 328 1407 10.1136/bmj.38118.593900.55 15175229
30. MS Petrov BP Loveday RD Pylypchuk, et al. 2009 Systematic review and meta-analysis of enteral nutrition formulations in acute pancreatitis Br J Surg 96 1243 1252 10.1002/bjs.6862 1:CAS:528:DC%2BD1MXhsFSqtbvO 19847860
31. R Pezzilli P Simoni R Casadei AM Morselli-Labate 2009 Exocrine pancreatic function during the early recovery phase of acute pancreatitis Hepatobiliary Pancreat Dis Int 8 316 319 19502175
32. T Symersky B van Hoorn AA Masclee 2006 The outcome of a long-term follow-up of pancreatic function after recovery from acute pancreatitis JOP 7 447 453 16998241
33. H Pelli R Lappalainen-Lehto A Piironen, et al. 2009 Pancreatic damage after the first episode of acute alcoholic pancreatitis and its association with the later recurrence rate Pancreatology 9 245 251 10.1159/000212089 19407478
34. SE Wright R Lochan K Imrie, et al. 2009 Quality of life and functional outcome at 3, 6 and 12 months after acute necrotising pancreatitis Intensive Care Med 35 1974 1978 10.1007/s00134-009-1616-z 19685037
35. R Pezzilli AM Morselli-Labate D Campana, et al. 2009 Evaluation of patient-reported outcome in subjects treated medically for acute pancreatitis: a follow-up study Pancreatology 9 375 382 10.1159/000181171 1:STN:280: DC%2BD1MvhtFOqsA%3D%3D 19451747
36. Nordback I, Pelli H, Lappalainen-Lehto R, et al.: The recurrence of acute alcohol-associated pancreatitis can be reduced: a randomized controlled trial. Gastroenterology 2009, 136:848-855. This randomized, controlled trial demonstrated a significant reduction in the recurrence of alcohol-associated pancreatitis with repeated 6-month interventions over a 2-year period.
37. K Ito H Ito EE Whang 2008 Timing of cholecystectomy for biliary pancreatitis: do the data support current guidelines? J Gastrointest Surg 12 2164 2170 10.1007/s11605-008-0603-y 18636298
38. DT Chiang G Thompson 2008 Management of acute gallstone pancreatitis: so the story continues ANZ J Surg 78 52 54 18199206
39. SJ Monkhouse EL Court I Dash NJ Coombs 2009 Two-week target for laparoscopic cholecystectomy following gallstone pancreatitis is achievable and cost neutral Br J Surg 96 751 755 10.1002/bjs.6644 1:STN:280: DC%2BD1MvjtFGqsQ%3D%3D 19526610
40. CA Nebiker DM Frey CT Hamel, et al. 2009 Early versus delayed cholecystectomy in patients with biliary acute pancreatitis Surgery 145 260 264 10.1016/j.surg.2008.10.012 19231577
41. Lankisch PG, Breuer N, Bruns A, et al.: Natural history of acute pancreatitis: a long-term population-based study. Am J Gastroenterol 2009, 104:2797-2805; quiz 2806.
42. D Yadav RH Hawes RE Brand, et al. 2009 Alcohol consumption, cigarette smoking, and the risk of recurrent acute and chronic pancreatitis Arch Intern Med 169 1035 1045 10.1001/archinternmed.2009.125 19506173
43. UC Bang C Nojgaard PK Andersen P Matzen 2009 Meta-analysis: nitroglycerin for prevention of post-ERCP pancreatitis Aliment Pharmacol Ther 29 1078 1085 10.1111/j.1365-2036.2009.03978.x 1:CAS:528:DC%2BD1MXmtVOlt78%3D 19236312
44. Rudin D: Somatostatin bolus injection for post-ERCP pancreatitis prevention: a need for further study. Gastrointest Endosc 2008, 67:190; author reply 190-191.
45. S Sherman WM Alazmi GA Lehman, et al. 2009 Evaluation of recombinant platelet-activating factor acetylhydrolase for reducing the incidence and severity of post-ERCP acute pancreatitis Gastrointest Endosc 69 3 Pt 1 462 472 10.1016/j.gie.2008.07.040 19231487
46. S Sherman CL Cheng G Costamagna, et al. 2009 Efficacy of recombinant human interleukin-10 in prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis in subjects with increased risk Pancreas 38 267 274 10.1097/MPA.0b013e31819777d5 1:CAS:528:DC%2BD1MXjsVyqsb8%3D 19214137
47. A Senol U Saritas H Demirkan 2009 Efficacy of intramuscular diclofenac and fluid replacement in prevention of post-ERCP pancreatitis World J Gastroenterol 15 3999 4004 10.3748/wjg.15.3999 19705494
48. A Singla J Simons Y Li, et al. 2009 Admission volume determines outcome for patients with acute pancreatitis Gastroenterology 137 1995 2001 10.1053/j.gastro.2009.08.056 19733570