The postmenopausal bladder

Menopause International

Volumn 16, Issue 2, 2010, Pages 74-80

  Hillard, Timothy ^a  

^a POOLE HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

estrogens; Postmenopausal; urinary incontinence; urogenital atrophy

Indexed keywords

CONJUGATED ESTROGEN; ESTRADIOL; ESTRIOL; ESTROGEN; ESTROGEN RECEPTOR; GESTAGEN; MEDROXYPROGESTERONE ACETATE; PROGESTERONE RECEPTOR; SEX HORMONE;

AGING; BLADDER; BLADDER FUNCTION; DETRUSOR MUSCLE; DISEASE ASSOCIATION; ESTROGEN DEFICIENCY; ESTROGEN THERAPY; FEMALE; HORMONE ACTION; HORMONE SUBSTITUTION; HUMAN; HYSTERECTOMY; LOW DRUG DOSE; LOWER URINARY TRACT SYMPTOM; MENOPAUSE; NOCTURIA; POSTMENOPAUSE; POSTMENOPAUSE OSTEOPOROSIS; PREVALENCE; RECURRENT INFECTION; REVIEW; STRESS INCONTINENCE; TREATMENT OUTCOME; URETHRA; URGE INCONTINENCE; URINARY TRACT INFECTION; URINE INCONTINENCE; UROGENITAL TRACT DISEASE; VAGINA ATROPHY; WOMEN'S HEALTH;

ADMINISTRATION, INTRAVAGINAL; AGE FACTORS; ESTROGEN REPLACEMENT THERAPY; FEMALE; HUMANS; POSTMENOPAUSE; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; URINARY BLADDER; URINARY INCONTINENCE; URINARY TRACT INFECTIONS;

EID: 77955884058     PISSN: 17540453     EISSN: 17540461     Source Type: Journal    
DOI: 10.1258/mi.2010.010020     Document Type: Review

References (72)

1. Thom D. Variation in estimates of urinary incontinence prevalence in the community: effects of differences in definition, population characteristics, and study type. J Am Geriatr Soc 1998; 46: 473–80
2. Mishra GD, Hardy R, Cardozo L, Kuh D. Body weight through adult life and risk of urinary incontinence in middle-aged women: results from a British prospective cohort. Int J Obes 2008; 32: 1415–22
3. Hunskaar S, Burgio KL, Diokno AC,, et al. Epidemiology and natural history of urinary incontinence. In: Abrams P, Cardozo L, Khoury S, Wein A, eds. Incontinence. Plymouth: Health Publication Limited, 2002: 165–201
4. Mishra GD, Cardozo L, Kuh D. Menopausal transition and the risk of urinary incontinence: results from a British prospective study. BJU Int 2010 DOI:10.111/j.1464-410X.2010.09321.x
5. Jolleys JV. Reported prevalence of urinary incontinence in a general practice. BMJ 1988; 296: 1300–2
6. Thomas TM, Plymat KR, Blannin J,, et al. Prevalence of urinary incontinence. BMJ 1980; 281: 1243–5
7. Kondo A, Kato K, Saito M, Otani T. Prevalence of incontinence in females in comparison with stress and urge incontinence. Neurourol Urodyn 1990; 9: 330–331
8. Miller YD, Brown WJ, Russell A,, et al. Urinary incontinence across the lifespan. Neurourol Urodyn 2003; 22: 550–557
9. Melville JL, Katon W, Delaney K,, et al. Urinary incontinence in US women: a population based study. Arch Intern Med 2005; 165: 537–42
10. Hannestad YS, Rortveit G, Daltveit AK, Hunskaar S. Are smoking and other lifestyle factors associated with female urinary incontinence? The Norwegian EPINCONT Study. Br J Obstet Gynaecol 2003; 110: 247–54
11. Nihira MA, Henderson N. Epidemiology of urinary incontinence in women. Curr Womens Health Rep 2003; 3: 340–347
12. Fultz NH, Herzog AR. Prevalence of urinary incontinence in middle-aged and older women: a survey-based methodological experiment. J AgingHealth 2000; 12: 459–69
13. Sherburn M, Guthrie JR, Dudley EC,, et al. Is incontinence associated with menopause? Obstet Gynecol 2001; 98: 628–33
14. Iosif CS, Bekassey Z. Prevalence of genito-urinary symptoms in the late menopause. Acta Obstet Gynecol Scand 1984; 63: 257–60
15. Barlow DH, Cardozo LD, Francis RM,, et al. Urogenital ageing and its effect on sexual health in older British women. Br J Obstet Gynecol 1997; 104: 87–91
16. Waetjen LE, Feng WY, Ye J,, et al. Factors associated with worsening and improving urinary incontinence across the menopausal transition. Obstet Gynecol 2008; 111: 667–77
17. Iosif CS, Batra S, Ek A,, et al. Estrogen receptors in the human female lower urinary tract. Am J Obstet Gynecol 1981; 141: 817–20
18. Blakeman PJ, Hilton P, Bulmer JN. Oestrogen and progestin receptor expression in the female lower urinary tract, with reference to oestrogen status. BJU Int 2000; 86: 32–38
19. Gebhardt J, Richard D, Barrett T. Expression of estrogen receptor isoforms alpha and beta messenger RNA in vaginal tissue of premenopausal and postmenopausal women. Am J Obstet Gynecol 2001; 185: 1325–30
20. Brocklehurst JC. Ageing of the human bladder. Geriatrics 1972; 27: 154
21. Perrucchini D, DeLancey JOL, Patane L,, et al. The number and diameter of striated muscle fibres in the female urethra. Neurourol Urodyn 1997; 16: 405–406
22. Kolbl H, Strassegger H, Riis PA. Morphological and functional aspects of pelvic floor muscles in patients with pelvic relaxation and genuine stress incontinence. Obstet Gynecol 1989; 74: 789–95
23. Malone Lee J, Waheda I. The characterisation of detrusor contractile function in relation to old age. Br J Urol 1993; 72: 873–80
24. Collas DM, Malone Lee J. Age associated changes in detrusor sensory function in women with lower urinary tract symptoms. Int Urognecol J 1996; 7: 24–29
25. Susset J, Plante P. Studies of female urethral pressure profile. Part II. Urethral pressure profile in female incontinence. J Urol 1980; 123: 70–74
26. Bhatia NN, Bergman A, Karram MM,, et al. Effects of estrogen on urethral function in women with urinary incontinence. Am J Obstet Gynecol 1989; 160: 176–81
27. Blakeman PJ, Hilton P, Bulmer JN. Cellular proliferation in the female lower urinary tract with reference to estrogen status. Br J Obstet Gynaecol 2001; 108: 813–16
28. Endo RM, Girao MJ, Sartori MG,, et al. Effect of estrogen–progestogen hormonal replacement therapy on peri-urethral and bladder vessels. Int Urogynecol J Pelvic Floor Dysfunct 2000; 11: 120–123
29. Rud T, Andersson KE, Asmussen M,, et al. Factors maintaining the intraurethral pressure in women. Invest Urol 1980; 17: 343–347
30. Callaghan SM, Creed KE. The effect of estrogens on spontaneous activities and responses to phenylepherine of the mammalian urethra. J Physiol 1985; 358: 35–46
31. Brincat MP, Baron YM, Galea R. Estrogens and the skin. Climacteric 2005; 8: 110–23
32. Versi E, Cardozo LD, Brincat MP,, et al. Correlation of urethral physiology and skin collagen in postmenopausal women. Br J Obstet Gynaecol 1988; 95: 147–52
33. Keane DP, Sims TJ, Abrams P,, et al. Analysis of collagen status in premenopausal nulliparous women with genuine stress incontinence. Br J Obstet Gynaecol 1997; 104: 994–998
34. Sartori MG, Girao MJ, de Jesus Simoes M,, et al. Quantitative evaluation of collagen and muscle fibres in the lower urinary tract of castrated rats and under-hormone replacement female rats. Clin Exp Obstet Gynecol 2001; 28: 92–96
35. Fantl JA, Wyman JF, Anderson RL,, et al. Postmenopausal urinary incontinence: comparison between non-estrogen and estrogen supplemented women. Obstet Gynecol 1988; 71: 823–828
36. Zoubina EV, Mize AL, Alper RH,, et al. Acute and chronic estrogen supplementation decreases uterine sympathetic innervations in ovariectomized adult virgin rats. Histol Histopathol 2001; 16: 989–96
37. Shenfield OZ, Blackmore PF, Morgan CW,, et al. Rapid effects of estradiol and progesterone on tone and spontaneous rhythmic contractions of the rabbit bladder. Neurourol Urodyn 1998; 17: 408–409
38. Elliott RA, Castleden CM, Miodrag A,, et al. The direct effects of diethylstilboestrol and nifedipine on the contractile responses of isolated human and rat detrsuor muscles. Eur J Clin Pharmacol 1992; 43: 149–55
39. Cutner A, Burton G, Cardozo LD,, et al. Does progesterone cause an irritable bladder? Int Urogynecol J 1993; 4: 261
40. Hextall A, Bidmead J, Cardozo LD,, et al. The impact of the menstrual cycle on urinary symptoms and the results of urodynamic investigation. Br J Obstet Gynaecol 2001; 108: 1193–6
41. Benness C, Gangar K, Cardozo LD,, et al. Do progestogens exacerbate urinary incontinence in women on HRT? Neurourol Urodyn 1991; 10: 316–18
42. Swift SE, Ostergaard DR. Effects of progesterone on the urinary tract. Int Urogynecol J 1993; 2: 232–236
43. Elliott RA, Castleden CM. Effects of progestogens and oestrogens on the contractile response of rat detrusor muscle to electrical field stimulation. Clin Sci 1994; 87: 337–42
44. Suckling J, Lethaby A, Kennedy R. Local oestrogen for vaginal atrophy in postmenopausal women. Cochrane Database Syst Rev 2006; CD001500
45. Cody JD, Richardson K, Moehrer B,, et al. Oestrogen therapy for urinary incontinence in postmenopausal women. Cochrane Database Syst Rev 2009; CD001405
46. Fantl JA, Cardozo LD, McClish DK. Estrogen therapy in the management of urinary incontinence in postmenopausal women: a meta-analysis. First report of the Hormones and Urogenital Therapy Committee (HUT). Obstet Gynecol 1994; 83: 12–18
47. Cardozo LD, Wise BG, Benness CJ. Vaginal oestradiol for the treatment of urinary tract symptoms in postmenopausal women – a double blind placebo controlled study. J Obstet Gynecol 2001; 21: 383–385
48. Long C-Y, Liu C-M, Hsu S-C, Chen Y-H, Wu C-H, Tsai E-M. A randomized comparative study of the effects of oral and topical estrogen therapy on the lower urinary tract of hysterectomized postmenopausal women. Fertil Steril 2006; 85: 155–60
49. Serati M, Salvatore S, Ucella S,, et al. Is there a synergestic effect of topical estrogens when administered with antimuscarinics in the treatment of symptomatic detrusor overactivity? Eur Urol 2009; 55: 713–19
50. Moehrer B, Hextall A, Jackson S. Oestrogens for urinary incontinence in women. Cochrane Database Syst Rev 2003; CD001405
51. Cardozo L, Lose G, McClish D,, et al. A systematic review of the effects of estrogens for symptoms suggestive of overactive bladder. Acta Obstet Gynecol Scand 2004; 83: 892–897
52. NICE. Urinary incontinence in women CG40 2006. See www.nice.org.uk/CG40 (last accessed 16 June 2010)
53. Al-Badr A, Ross S, Soroka D,, et al. What is the available evidence for hormone replacement therapy for women with stress urinary incontinence? J Obstet Gynecol Can 2003; 25: 567–74
54. Grodstein F, Lifford K, Resnick NM,, et al. Postmenopausal hormone therapy and risk of developing urinary incontinence. Obstet Gynecol 2004; 103: 254–60
55. Steinauer JE, Waetjen LE, Vittinghoff E,, et al. Postmenopausal hormone therapy: does it cause incontinence? Obstet Gynecol 2005; 106: 940–945
56. Hendrix SL, Cochrane BB, Nygaard IE,, et al. Effects of estrogen with and without progestin on urinary incontinence. JAMA 2005; 293: 935–48
57. Shamliyan TA, Kane RL, Wyman J,, et al. Systematic review: randomised controlled trials of non surgical treatments for urinary incontinence in women. Ann Intern Med 2008; 148: 459–73
58. Akhila V, Pratap Kumar. A comparison of transdermal and oral HRT for menopausal symptom control. Int J Fertil Womens Med 2006; 51: 64–69
59. Waetjen LE, Brown JS, Vittinghoff E,, et al. The effect of ultralow-dose transdermal estradiol on urinary incontinence in postmenopausal women. Obstet Gynecol 2005; 106: 946–52
60. Jackson S, James M, Abrams P. The effect of oestradiol on vaginal collagen metabolism in postmenopausal women with genuine stress incontinence. Br J Obstet Gynaecol 2002; 109: 339–44
61. Edwall L, Carlström K, Jonasson AF. Endocrine status and markers of collagen synthesis and degradation in serum and urogenital tissue form women with and without stress urinary incontinence. Neurol Urodyn 2007; 26: 410–15
62. Hextall A, Hooper R, Cardozo LD,, et al. Does the menopause influence the risk of bacteriuria? Int J Urogynecol J Pelvic Floor Dysfunct 2001; 12: 332–336
63. Raz R, Stamm WE. A controlled trial of intravaginal estriol in postmenopausal women with recurrent urinary tract infections. N Engl J Med 1993; 329: 753–756
64. Cardozo LD, Benness C, Abbot D. Low dose oestrogen prophylaxis for recurrent urinary tract infections in elderly women. Br J Obstet Gynecol 1998; 105: 403–407
65. Eriksen B. A randomized open parallel group study on the preventative effect of an estradiol releasing vaginal ring (Estring) on recurrent urinary tract infections in postmenopausal women. Am J Obstet Gynecol 1999; 180: 1072–9
66. Cardozo LD, Lose G, McClish D,, et al. A systematic review of estrogens for recurrent urinary tract infections: third report of the hormones and urogenital therapy (HUT) committee. Int Urogynecol J Pelvic Floor Dysfunct 2001; 12: 15–20
67. Moore EE, Jackson SL, Boyko EJ,, et al. Urinary incontinence and urinary tract infection: temporal relationships in postmenopausal women. Obstet Gynecol 2008; 111: 317–23
68. Pitkin J, Rees M. Urogenital atrophy. Menopause Int 2008; 14: 136–137
69. Guthrie JR, Dennerstein L, Taffe JR,, et al. The menopausal transition: a 9-year prospective population-based study. The Melbourne Women's Midlife Health Project. Climacteric 2004; 7: 375–89
70. Versi E, Harvey MA, Cardozo LD,, et al. Urogenital prolapse and atrophy at menopause: a prevalence study. Int Urogynecol J Pelvic Floor Dysfunct 2001; 12: 107–10
71. Cardozo LD, Bachmann G, McClish D,, et al. Meta-analysis of estrogen therapy in the management of urogenital atrophy in postmenopausal women: second report of the Hormones and Urogenital Therapy Committee. Obstet Gynecol 1998; 92: 722–727
72. Weisberg E, Ayton R, Darling G,, et al. Endometrial and vaginal effects of low-dose estradiol delivered by vaginal ring or vaginal tablet. Climacteric 2005; 8: 83–92