메뉴 건너뛰기




Volumn 43, Issue 5-6, 2010, Pages 401-412

Thymic remodeling associated with hyperplasia in myasthenia gravis

Author keywords

chemokines; germinal centers; inflammation; Myasthenia; thymus

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CD31 ANTIGEN; CHEMOKINE RECEPTOR CCR7; CHOLINERGIC RECEPTOR ANTIBODY; CORTICOSTEROID; CXCL13 CHEMOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLUCOCORTICOID; HOMEODOMAIN PROTEIN; INTERFERON; INTERFERON ANTIBODY; INTERLEUKIN 1; INTERLEUKIN 2; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; PROSPERO HOMEOBOX PROTEIN 1; RANTES; SECONDARY LYMPHOID TISSUE CHEMOKINE; STROMAL CELL DERIVED FACTOR 1; TRANSCRIPTOME; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 3;

EID: 77955874378     PISSN: 08916934     EISSN: 1607842X     Source Type: Journal    
DOI: 10.3109/08916930903563491     Document Type: Review
Times cited : (62)

References (113)
  • 2
    • 0016800062 scopus 로고
    • Humoral antibodies to acetylcholine receptor in patients with myasthenia gravis
    • Aharonov A, Abramsky O, Tarrab-Hazdai R, Fuchs S. Humoral antibodies to acetylcholine receptor in patients with myasthenia gravis. Lancet 1975;2(7930):340-342.
    • (1975) Lancet , vol.2 , Issue.7930 , pp. 340-342
    • Aharonov, A.1    Abramsky, O.2    Tarrab-Hazdai, R.3    Fuchs, S.4
  • 3
    • 0035105784 scopus 로고    scopus 로고
    • Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies
    • HochW, McConville J, Helms S, Newsom-Davis J, Melms A, Vincent A. Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies. Nature Med 2001;7(3): 365-368.
    • (2001) Nature Med , vol.7 , Issue.3 , pp. 365-368
    • Hochw McConville, J.1    Helms, S.2    Newsom-Davis, J.3    Melms, A.4    Vincent, A.5
  • 6
    • 0032752802 scopus 로고    scopus 로고
    • Thymus et pathologies
    • Berrih-Aknin S, Eymard B. Thymus et pathologies. Biologie 1999;5(7):579-585.
    • (1999) Biologie , vol.5 , Issue.7 , pp. 579-585
    • Berrih-Aknin, S.1    Eymard, B.2
  • 9
    • 0029988314 scopus 로고    scopus 로고
    • The thymus and the pathogenesis of myasthenia gravis
    • Levinson AI, Wheatley LM. The thymus and the pathogenesis of myasthenia gravis. Clin Immunol Immunopathol 1996;78(1):1-5.
    • (1996) Clin Immunol Immunopathol , vol.78 , Issue.1 , pp. 1-5
    • Levinson, A.I.1    Wheatley, L.M.2
  • 11
    • 0025819525 scopus 로고
    • The TH. Antiacetylcholine receptor antibodies decrease after thymectomy in patients with myasthenia gravis. Clinical correlations
    • Kuks JB, Oosterhuis HJ, Limburg PC, The TH. Antiacetylcholine receptor antibodies decrease after thymectomy in patients with myasthenia gravis. Clinical correlations. J Autoimmun 1991;4(2):197-211.
    • (1991) J Autoimmun , vol.4 , Issue.2 , pp. 197-211
    • Kuks, J.B.1    Oosterhuis, H.J.2    Limburg, P.C.3
  • 12
    • 0030587964 scopus 로고    scopus 로고
    • Expression of acetylcholine receptor genes in human thymic epithelial cells: Implications for myasthenia gravis
    • Wakkach A, Guyon T, Bruand C, Tzartos S, Cohen- Kaminsky S, Berrih-Aknin S. Expression of acetylcholine receptor genes in human thymic epithelial cells: Implications for myasthenia gravis. J Immunol 1996;157(8):3752-3760.
    • (1996) J Immunol , vol.157 , Issue.8 , pp. 3752-3760
    • Wakkach, A.1    Guyon, T.2    Bruand, C.3    Tzartos, S.4    Cohen- Kaminsky, S.5    Berrih-Aknin, S.6
  • 13
    • 0023263064 scopus 로고
    • In vitro anti-acetylcholine receptor antibody synthesis by myasthenia gravis patient lymphocytes: Correlations with thymic histology and thymic epithelial-cell interactions
    • Safar D, Berrih-Aknin S, Morel E. In vitro anti-acetylcholine receptor antibody synthesis by myasthenia gravis patient lymphocytes: Correlations with thymic histology and thymic epithelial-cell interactions. J Clin Immunol 1987;7(3): 225-234.
    • (1987) J Clin Immunol , vol.7 , Issue.3 , pp. 225-234
    • Safar, D.1    Berrih-Aknin, S.2    Morel, E.3
  • 15
    • 0023841883 scopus 로고
    • Thymus in myasthenia gravis. Isolation of T-lymphocyte lines specific for the nicotinic acetylcholine receptor from thymuses of myasthenic patients
    • Melms A, Schalke BC, Kirchner T, Muller-Hermelink HK, Albert E, Wekerle H. Thymus in myasthenia gravis. Isolation of T-lymphocyte lines specific for the nicotinic acetylcholine receptor from thymuses of myasthenic patients. J Clin Invest 1988;81(3):902-908.
    • (1988) J Clin Invest , vol.81 , Issue.3 , pp. 902-908
    • Melms, A.1    Schalke, B.C.2    Kirchner, T.3    Muller-Hermelink, H.K.4    Albert, E.5    Wekerle, H.6
  • 16
    • 0025992693 scopus 로고
    • The thymus in myasthenia gravis. Changes typical for the human disease are absent in experimental autoimmune myasthenia gravis of the Lewis rat
    • Meinl E, KlinkertWE,Wekerle H. The thymus in myasthenia gravis. Changes typical for the human disease are absent in experimental autoimmune myasthenia gravis of the Lewis rat. Am J Pathol 1991;139(5):995-1008.
    • (1991) Am J Pathol , vol.139 , Issue.5 , pp. 995-1008
    • Meinl, E.1    Klinkertwewekerle, H.2
  • 17
    • 0015045109 scopus 로고
    • Studies in myasthenia gravis: Effects of thymectomy. Results on 185 patients with nonthymomatous and thymomatous myasthenia gravis, 1941-1969
    • Papatestas AE, Alpert LI, Osserman KE, Osserman RS, Kark AE. Studies in myasthenia gravis: Effects of thymectomy. Results on 185 patients with nonthymomatous and thymomatous myasthenia gravis, 1941-1969. Am J Med 1971;50(4):465-474.
    • (1971) Am J Med , vol.50 , Issue.4 , pp. 465-474
    • Papatestas, A.E.1    Alpert, L.I.2    Osserman, K.E.3    Osserman, R.S.4    Kark, A.E.5
  • 18
    • 58149389093 scopus 로고    scopus 로고
    • A comparison of long-term post-thymectomy outcome of anti-AChR-positive, anti-AChR-negative and anti-MuSK-positive patients with non-thymomatous myasthenia gravis
    • Ponseti JM, Caritg N, Gamez J, Lopez-Cano M, Vilallonga R, Armengol M. A comparison of long-term post-thymectomy outcome of anti-AChR-positive, anti-AChR-negative and anti-MuSK-positive patients with non-thymomatous myasthenia gravis. Expert Opin Biol Ther 2009;9(1):1-8.
    • (2009) Expert Opin Biol Ther , vol.9 , Issue.1 , pp. 1-8
    • Ponseti, J.M.1    Caritg, N.2    Gamez, J.3    Lopez-Cano, M.4    Vilallonga, R.5    Armengol, M.6
  • 25
    • 0021793969 scopus 로고
    • Extracellular matrix of the human thymus: Immunofluorescence studies on frozen sections and cultured epithelial cells
    • Berrih S, Savino W, Cohen S. Extracellular matrix of the human thymus: Immunofluorescence studies on frozen sections and cultured epithelial cells. J Histochem Cytochem 1985;33(7):655-664.
    • (1985) J Histochem Cytochem , vol.33 , Issue.7 , pp. 655-664
    • Berrih, S.1    Savino, W.2    Cohen, S.3
  • 26
    • 0021329452 scopus 로고
    • Anti-AChR antibodies, thymic histology, and T-cell subsets in myasthenia gravis
    • Berrih S, Morel E, Gaud C, Raimond F, Le Brigand H, Bach JF. Anti-AChR antibodies, thymic histology, and T-cell subsets in myasthenia gravis. Neurology 1984;34(1):66-71.
    • (1984) Neurology , vol.34 , Issue.1 , pp. 66-71
    • Berrih, S.1    Morel, E.2    Gaud, C.3    Raimond, F.4    Le Brigand, H.5    Bach, J.F.6
  • 27
    • 0034807306 scopus 로고    scopus 로고
    • B cells in epithelial and perivascular compartments of human adult thymus
    • Flores KG, Li J, Hale LP. B cells in epithelial and perivascular compartments of human adult thymus. Hum Pathol 2001; 32(9):926-934.
    • (2001) Hum Pathol , vol.32 , Issue.9 , pp. 926-934
    • Flores, K.G.1    Li, J.2    Hale, L.P.3
  • 28
    • 0015583707 scopus 로고
    • Altered venules in the stimulated human thymus as evidence of lymphocyte recirculation
    • Bradfield JW. Altered venules in the stimulated human thymus as evidence of lymphocyte recirculation. Clin Exp Immunol 1973;13(2):243-252.
    • (1973) Clin Exp Immunol , vol.13 , Issue.2 , pp. 243-252
    • Bradfield, J.W.1
  • 29
    • 0015814421 scopus 로고
    • The incidence of germinal centres in thymus glands of patients with congenital heart disease
    • Vetters M, Barclay RS. The incidence of germinal centres in thymus glands of patients with congenital heart disease. J Clin Pathol 1973;26(8):583-591.
    • (1973) J Clin Pathol , vol.26 , Issue.8 , pp. 583-591
    • Vetters, M.1    Barclay, R.S.2
  • 31
    • 33751558801 scopus 로고    scopus 로고
    • Microarrays reveal distinct gene signatures in the thymus of seropositive and seronegative myasthenia gravis patients and the role of CCL21 in thymic hyperplasia
    • Le Panse R, Cizeron-Clairac G, Bismuth J, Berrih Aknin S. Microarrays reveal distinct gene signatures in the thymus of seropositive and seronegative myasthenia gravis patients and the role of CCL21 in thymic hyperplasia. J Immunol 2006; 177:7868-7879.
    • (2006) J Immunol , vol.177 , pp. 7868-7879
    • Le Panse, R.1    Cizeron-Clairac, G.2    Bismuth, J.3    Berrih Aknin, S.4
  • 35
    • 0035881829 scopus 로고    scopus 로고
    • Somatic hypermutation and selection of B cells in thymic germinal centers responding to acetylcholine receptor in myasthenia gravis
    • Sims GP, Shiono H, Willcox N, Stott DI. Somatic hypermutation and selection of B cells in thymic germinal centers responding to acetylcholine receptor in myasthenia gravis. J Immunol 2001;167(4):1935-1944.
    • (2001) J Immunol , vol.167 , Issue.4 , pp. 1935-1944
    • Sims, G.P.1    Shiono, H.2    Willcox, N.3    Stott, D.I.4
  • 36
    • 0026081375 scopus 로고
    • Individual germinal centres of myasthenia gravis human thymuses contain polyclonal activated B cells that express all the Vh and Vk families
    • Guigou V, Emilie D, Berrih-Aknin S, Fumoux F, Fougereau M, Schiff C. Individual germinal centres of myasthenia gravis human thymuses contain polyclonal activated B cells that express all the Vh and Vk families. Clin Exp Immunol 1991;83(2):262-266.
    • (1991) Clin Exp Immunol , vol.83 , Issue.2 , pp. 262-266
    • Guigou, V.1    Emilie, D.2    Berrih-Aknin, S.3    Fumoux, F.4    Fougereau, M.5    Schiff, C.6
  • 37
    • 0014876589 scopus 로고
    • Postcapillary venules of the lymph node type in the thymus in myasthenia
    • Soderstrom N, Axelsson JA, Hagelqvist E. Postcapillary venules of the lymph node type in the thymus in myasthenia. Lab Invest 1970;23(5):451-458.
    • (1970) Lab Invest , vol.23 , Issue.5 , pp. 451-458
    • Soderstrom, N.1    Axelsson, J.A.2    Hagelqvist, E.3
  • 38
    • 0029153736 scopus 로고
    • High endothelial venules (HEVs): Specialized endothelium for lymphocyte migration
    • Girard JP, Springer TA. High endothelial venules (HEVs): Specialized endothelium for lymphocyte migration. Immunol Today 1995;16(9):449-457.
    • (1995) Immunol Today , vol.16 , Issue.9 , pp. 449-457
    • Girard, J.P.1    Springer, T.A.2
  • 40
    • 0032921630 scopus 로고    scopus 로고
    • Local immune responses in afferent and efferent lymph
    • Haig DM, Hopkins J, Miller HR. Local immune responses in afferent and efferent lymph. Immunology 1999;96(2): 155-163.
    • (1999) Immunology , vol.96 , Issue.2 , pp. 155-163
    • Haig, D.M.1    Hopkins, J.2    Miller, H.R.3
  • 43
    • 33750475605 scopus 로고    scopus 로고
    • Normal structure, function and histology of the thymus
    • Pearse G. Normal structure, function and histology of the thymus. Toxicol Pathol 2006;34(5):504-514.
    • (2006) Toxicol Pathol , vol.34 , Issue.5 , pp. 504-514
    • Pearse, G.1
  • 44
    • 0037407337 scopus 로고    scopus 로고
    • Dendritic cells in hyperplastic thymuses from patients with myasthenia gravis
    • Nagane Y, Utsugisawa K, Obara D, Yamagata M, Tohgi H. Dendritic cells in hyperplastic thymuses from patients with myasthenia gravis. Muscle Nerve 2003;27(5):582-589.
    • (2003) Muscle Nerve , vol.27 , Issue.5 , pp. 582-589
    • Nagane, Y.1    Utsugisawa, K.2    Obara, D.3    Yamagata, M.4    Tohgi, H.5
  • 45
    • 0024261308 scopus 로고
    • Production of interleukin 1 (IL1) by human thymic epithelial cells (TEC)
    • Cohen-Kaminsky S, Berrih-Aknin S. Production of interleukin 1 (IL1) by human thymic epithelial cells (TEC). Adv Exp Med Biol 1988;237:299-305.
    • (1988) Adv Exp Med Biol , vol.237 , pp. 299-305
    • Cohen-Kaminsky, S.1    Berrih-Aknin, S.2
  • 47
    • 0027163842 scopus 로고
    • Interleukin-6 overproduction by cultured thymic epithelial cells from patients with myasthenia gravis is potentially involved in thymic hyperplasia
    • Cohen-Kaminsky S, Devergne O, Delattre RM, Klingel- Schmitt I, Emilie D, Galanaud P, Berrih-Aknin S. Interleukin-6 overproduction by cultured thymic epithelial cells from patients with myasthenia gravis is potentially involved in thymic hyperplasia. Eur Cytokine Netw 1993; 4(2):121-132. (Pubitemid 23170950)
    • (1993) European Cytokine Network , vol.4 , Issue.2 , pp. 121-132
    • Cohen-Kaminsky, S.1    Devergne, O.2    Delattre, R.-M.3    Klingel-Schmitt, I.4    Emilie, D.5    Galanaud, P.6    Berrih-Aknin, S.7
  • 48
    • 27744547953 scopus 로고    scopus 로고
    • Constitutive activation of p38 and ERK1/2 MAPKs in epithelial cells of myasthenic thymus leads to IL-6 and RANTES overexpression: Effects on survival and migration of peripheral Tand B cells
    • Colombara M, Antonini V, Riviera AP, Mainiero F, Strippoli R, Merola M, Fracasso G, Poffe O, Brutti N, Tridente G, Colombatti M, Ramarli D. Constitutive activation of p38 and ERK1/2 MAPKs in epithelial cells of myasthenic thymus leads to IL-6 and RANTES overexpression: Effects on survival and migration of peripheral Tand B cells. J Immunol 2005;175(10):7021-7028.
    • (2005) J Immunol , vol.175 , Issue.10 , pp. 7021-7028
    • Colombara, M.1    Antonini, V.2    Riviera, A.P.3    Mainiero, F.4    Strippoli, R.5    Merola, M.6    Fracasso, G.7    Poffe, O.8    Brutti, N.9    Tridente, G.10    Colombatti, M.11    Ramarli, D.12
  • 50
    • 11244291391 scopus 로고    scopus 로고
    • Functional defect of regulatory CD4(+)CD25+ T cells in the thymus of patients with autoimmune myasthenia gravis
    • BalandinaA, Lecart S,Dartevelle P, SaoudiA,Berrih-Aknin S. Functional defect of regulatory CD4(+)CD25+ T cells in the thymus of patients with autoimmune myasthenia gravis. Blood 2005;105(2):735-741.
    • (2005) Blood , vol.105 , Issue.2 , pp. 735-741
    • Balandina, A.1    Lecart, S.2    Dartevelle, P.3    Saoudiaberrih-Aknin, S.4
  • 51
    • 0032103108 scopus 로고    scopus 로고
    • An acetylcholine receptor alpha subunit promoter confers intrathymic expression in transgenic mice. Implications for tolerance of a transgenic self-antigen and for autoreactivity in myasthenia gravis
    • Salmon AM, Bruand C, Cardona A, Changeux JP, Berrih-Aknin S. An acetylcholine receptor alpha subunit promoter confers intrathymic expression in transgenic mice. Implications for tolerance of a transgenic self-antigen and for autoreactivity in myasthenia gravis. J Clin Invest 1998; 101(11):2340-2350.
    • (1998) J Clin Invest , vol.101 , Issue.11 , pp. 2340-2350
    • Salmon, A.M.1    Bruand, C.2    Cardona, A.3    Changeux, J.P.4    Berrih-Aknin, S.5
  • 52
    • 18244421874 scopus 로고    scopus 로고
    • The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes
    • Pugliese A, Zeller M, Fernandez A, Jr, Zalcberg LJ, Bartlett RJ, Ricordi C, Pietropaolo M, Eisenbarth GS, Bennett ST, Patel DD. The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes. Nat Genet 1997;15(3):293-297.
    • (1997) Nat Genet , vol.15 , Issue.3 , pp. 293-297
    • Pugliese, A.1    Zeller, M.2    Fernandez, A.3    Zalcberg Jr., L.J.4    Bartlett, R.J.5    Ricordi, C.6    Pietropaolo, M.7    Eisenbarth, G.S.8    Bennett, S.T.9    Patel, D.D.10
  • 54
    • 0032952547 scopus 로고    scopus 로고
    • Acetylcholine receptor alpha subunit mRNA expression in human thymus: Augmented expression in myasthenia gravis and nupregulation by interferon-gamma
    • Zheng Y, Wheatley LM, Liu T, Levinson AI. Acetylcholine receptor alpha subunit mRNA expression in human thymus: Augmented expression in myasthenia gravis and nupregulation by interferon-gamma. Clin Immunol 1999; 91(2):170-177.
    • (1999) Clin Immunol , vol.91 , Issue.2 , pp. 170-177
    • Zheng, Y.1    Wheatley, L.M.2    Liu, T.3    Levinson, A.I.4
  • 55
    • 0018595814 scopus 로고
    • Myosin and actin containing cells in the human postnatal thymus Ultrastructural and immunohistochemical findings in normal thymus and in myasthenia gravis
    • Drenckhahn D, von Gaudecker B, Muller-Hermelink H, Unsicker K, Groschel-Stewart U. Myosin and actin containing cells in the human postnatal thymus. Ultrastructural and immunohistochemical findings in normal thymus and in myasthenia gravis. Virchows Arch B Cell Pathol Mol Pathol 1979;23(1):33-45.
    • (1979) Virchows Arch B Cell Pathol Mol Pathol , vol.23 , Issue.1 , pp. 33-45
    • Drenckhahn, D.1    Von Gaudecker, B.2    Muller-Hermelink, H.3    Unsicker, K.4    Groschel-Stewart, U.5
  • 58
    • 0036231364 scopus 로고    scopus 로고
    • Thymic myoid cells and germinal center formation in myasthenia gravis; Possible roles in pathogenesis
    • Roxanis I, Micklem K, McConville J, Newsom-Davis J, Willcox N. Thymic myoid cells and germinal center formation in myasthenia gravis; possible roles in pathogenesis. J Neuroimmunol 2002;125(1-2):185-197.
    • (2002) J Neuroimmunol , vol.125 , Issue.1-2 , pp. 185-197
    • Roxanis, I.1    Micklem, K.2    McConville, J.3    Newsom-Davis, J.4    Willcox, N.5
  • 60
    • 0027372469 scopus 로고
    • Immune activation in myasthenia gravis: Soluble interleukin-2 receptor, interferon-gamma and tumor necrosis factor-alpha levels inpatients'serum
    • Confalonieri P, Antozzi C, Cornelio F, Simoncini O, Mantegazza R. Immune activation in myasthenia gravis: Soluble interleukin-2 receptor, interferon-gamma and tumor necrosis factor-alpha levels inpatients'serum. JNeuroimmunol 1993;48(1):33-36.
    • (1993) JNeuroimmunol , vol.48 , Issue.1 , pp. 33-36
    • Confalonieri, P.1    Antozzi, C.2    Cornelio, F.3    Simoncini, O.4    Mantegazza, R.5
  • 61
    • 0036240295 scopus 로고    scopus 로고
    • Cytokine secretion by peripheral blood mononuclear cells in myasthenia gravis
    • Yoshikawa H, Satoh K, Yasukawa Y, Yamada M. Cytokine secretion by peripheral blood mononuclear cells in myasthenia gravis. J Clin Neurosci 2002;9(2):133-136.
    • (2002) J Clin Neurosci , vol.9 , Issue.2 , pp. 133-136
    • Yoshikawa, H.1    Satoh, K.2    Yasukawa, Y.3    Yamada, M.4
  • 64
    • 0026737681 scopus 로고
    • Recombinant interferon gamma for treatment of chronic granulomatous disease and other disorders
    • quiz 92-94
    • Bolinger AM, Taeubel MA. Recombinant interferon gamma for treatment of chronic granulomatous disease and other disorders. Clin Pharm 1992;11(10):834-850, quiz 92-94.
    • (1992) Clin Pharm , vol.11 , Issue.10 , pp. 834-850
    • Bolinger, A.M.1    Taeubel, M.A.2
  • 66
    • 0029927531 scopus 로고    scopus 로고
    • Development of myasthenia gravis during interferon-alpha treatment for anti-HCV positive chronic hepatitis
    • Mase G, Zorzon M, Biasutti E, Vitrani B, Cazzato G, Urban F, Frezza M. Development of myasthenia gravis during interferon-alpha treatment for anti-HCV positive chronic hepatitis. J Neurol Neurosurg Psych 1996;60(3): 348-349.
    • (1996) J Neurol Neurosurg Psych , vol.60 , Issue.3 , pp. 348-349
    • Mase, G.1    Zorzon, M.2    Biasutti, E.3    Vitrani, B.4    Cazzato, G.5    Urban, F.6    Frezza, M.7
  • 67
    • 3042747338 scopus 로고    scopus 로고
    • Development of myasthenia gravis in two patients with multiple sclerosis following interferon beta treatment
    • Dionisiotis J, Zoukos Y, Thomaides T. Development of myasthenia gravis in two patients with multiple sclerosis following interferon beta treatment. J Neurol Neurosurg Psych 2004;75(7):1079.
    • (2004) J Neurol Neurosurg Psych , vol.75 , Issue.7 , pp. 1079
    • Dionisiotis, J.1    Zoukos, Y.2    Thomaides, T.3
  • 69
    • 0037387254 scopus 로고    scopus 로고
    • Anti-cytokine autoantibodies in autoimmunity: Preponderance of neutralizing autoantibodies against interferon-alpha, interferon-omega and interleukin-12 in patients with thymoma and/or myasthenia gravis
    • Meager A, Wadhwa M, Dilger P, Bird C, Thorpe R, Newsom-Davis J, Willcox N. Anti-cytokine autoantibodies in autoimmunity: Preponderance of neutralizing autoantibodies against interferon-alpha, interferon-omega and interleukin-12 in patients with thymoma and/or myasthenia gravis. Clin Exp Immunol 2003;132(1):128-136.
    • (2003) Clin Exp Immunol , vol.132 , Issue.1 , pp. 128-136
    • Meager, A.1    Wadhwa, M.2    Dilger, P.3    Bird, C.4    Thorpe, R.5    Newsom-Davis, J.6    Willcox, N.7
  • 71
    • 33745712576 scopus 로고    scopus 로고
    • The thymus is a common target organ in infectious diseases
    • SavinoW. The thymus is a common target organ in infectious diseases. PLoS Pathog 2006;2(6):e62.
    • (2006) PLoS Pathog , vol.2 , Issue.6
    • Savino, W.1
  • 72
    • 28444494764 scopus 로고    scopus 로고
    • Infections and autoimmune diseases
    • Bach JF. Infections and autoimmune diseases. J Autoimmun 2005;25S:74-80.
    • (2005) J Autoimmun , vol.25 S , pp. 74-80
    • Bach, J.F.1
  • 73
    • 0024429029 scopus 로고
    • OldstoneMB. Molecular mimicry and myasthenia gravis. An autoantigenic site of the acetylcholine receptor alpha-subunit that has biologic activity and reacts immunochemically with herpes simplex virus
    • Schwimmbeck PL, Dyrberg T, Drachman DB, OldstoneMB. Molecular mimicry and myasthenia gravis. An autoantigenic site of the acetylcholine receptor alpha-subunit that has biologic activity and reacts immunochemically with herpes simplex virus. J Clin Invest 1989;84(4):1174-1180.
    • (1989) J Clin Invest , vol.84 , Issue.4 , pp. 1174-1180
    • Schwimmbeck, P.L.1    Dyrberg, T.2    Drachman, D.B.3
  • 74
    • 0025124714 scopus 로고
    • Interferon system and natural killer cell activity in myasthenia gravis
    • Kott E, Hahn T, Huberman M, Levin S, Schattner A. Interferon system and natural killer cell activity in myasthenia gravis. Q J Med 1990;76(281):951-960.
    • (1990) Q J Med , vol.76 , Issue.281 , pp. 951-960
    • Kott, E.1    Hahn, T.2    Huberman, M.3    Levin, S.4    Schattner, A.5
  • 75
    • 33748306209 scopus 로고    scopus 로고
    • Toll-like receptors and IFN-alpha: Partners in autoimmunity
    • Colonna M. Toll-like receptors and IFN-alpha: Partners in autoimmunity. J Clin Invest 2006;116(9):2319-2322.
    • (2006) J Clin Invest , vol.116 , Issue.9 , pp. 2319-2322
    • Colonna, M.1
  • 76
    • 33747815094 scopus 로고    scopus 로고
    • Endogenous TLR ligands and autoimmunity
    • Wagner H. Endogenous TLR ligands and autoimmunity. Adv Immunol 2006;91:159-173.
    • (2006) Adv Immunol , vol.91 , pp. 159-173
    • Wagner, H.1
  • 79
    • 0030878993 scopus 로고    scopus 로고
    • Interferon gamma (IFNgamma) is necessary for the genesis of acetylcholine receptor-induced clinical experimental autoimmune myasthenia gravis in mice
    • Balasa B, Deng C, Lee J, Bradley LM, Dalton DK, Christadoss P, Sarvetnick N. Interferon gamma (IFNgamma) is necessary for the genesis of acetylcholine receptor-induced clinical experimental autoimmune myasthenia gravis in mice. J Exp Med 1997;186(3):385-391.
    • (1997) J Exp Med , vol.186 , Issue.3 , pp. 385-391
    • Balasa, B.1    Deng, C.2    Lee, J.3    Bradley, L.M.4    Dalton, D.K.5    Christadoss, P.6    Sarvetnick, N.7
  • 80
    • 0033120962 scopus 로고    scopus 로고
    • Mice with IFN-gamma receptor deficiency are less susceptible to experimental autoimmune myasthenia gravis
    • Zhang GX, Xiao BG, Bai XF, Van Der Meide PH, Orn A, Link H. Mice with IFN-gamma receptor deficiency are less susceptible to experimental autoimmune myasthenia gravis. J Immunol 1999;162(7):3775-3781.
    • (1999) J Immunol , vol.162 , Issue.7 , pp. 3775-3781
    • Zhang, G.X.1    Xiao, B.G.2    Bai, X.F.3    Van Der Meide, P.H.4    Orn, A.5    Link, H.6
  • 81
    • 67649997620 scopus 로고    scopus 로고
    • IFN-gamma-STAT1 signal regulates the differentiation of inducible Treg: Potential role for ROS-mediated apoptosis
    • Chang JH, Kim YJ, Han SH, Kang CY. IFN-gamma-STAT1 signal regulates the differentiation of inducible Treg: Potential role for ROS-mediated apoptosis. Eur J Immunol 2009;39(5):1241-1251.
    • (2009) Eur J Immunol , vol.39 , Issue.5 , pp. 1241-1251
    • Chang, J.H.1    Kim, Y.J.2    Han, S.H.3    Kang, C.Y.4
  • 82
    • 0032797272 scopus 로고    scopus 로고
    • Chemokines and cell migration in secondary lymphoid organs
    • Cyster JG. Chemokines and cell migration in secondary lymphoid organs. Science 1999;286(5447):2098-2102.
    • (1999) Science , vol.286 , Issue.5447 , pp. 2098-2102
    • Cyster, J.G.1
  • 83
    • 0032536373 scopus 로고    scopus 로고
    • B-cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5
    • LeglerDF,LoetscherM,RoosRS,Clark-Lewis I,BaggioliniM, Moser B. B-cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5. J Exp Med 1998;187(4): 655-660.
    • (1998) J Exp Med , vol.187 , Issue.4 , pp. 655-660
    • Legler, D.F.1    Loetscher, M.2    Roos, R.S.3    Clark-Lewis, I.4    Baggiolini, M.5    Moser, B.6
  • 84
    • 0038240921 scopus 로고    scopus 로고
    • Ectopic germinal center formation in rheumatoid synovitis
    • Weyand CM, Goronzy JJ. Ectopic germinal center formation in rheumatoid synovitis. Ann N Y Acad Sci 2003;987: 140-149.
    • (2003) Ann N y Acad Sci , vol.987 , pp. 140-149
    • Weyand, C.M.1    Goronzy, J.J.2
  • 85
    • 34249826618 scopus 로고    scopus 로고
    • Aberrant B1-cell trafficking in a murine model for lupus
    • Ishikawa S, Matsushima K. Aberrant B1-cell trafficking in a murine model for lupus. Front Biosci 2007;12:1790-1803.
    • (2007) Front Biosci , vol.12 , pp. 1790-1803
    • Ishikawa, S.1    Matsushima, K.2
  • 87
    • 0036570610 scopus 로고    scopus 로고
    • CXCR5(+) T cells: Follicular homing takes center stage in T-helper-cell responses
    • Moser B, Schaerli P, Loetscher P. CXCR5(+) T cells: Follicular homing takes center stage in T-helper-cell responses. Trends Immunol 2002;23(5):250-254.
    • (2002) Trends Immunol , vol.23 , Issue.5 , pp. 250-254
    • Moser, B.1    Schaerli, P.2    Loetscher, P.3
  • 91
    • 0029076264 scopus 로고
    • T-cell receptor expression in the thymus from patients with myasthenia gravis
    • Berrih-Aknin S, Cohen-Kaminsky S, Truffault F. T-cell receptor expression in the thymus from patients with myasthenia gravis. Ann N Y Acad Sci 1995;756:438-440.
    • (1995) Ann N y Acad Sci , vol.756 , pp. 438-440
    • Berrih-Aknin, S.1    Cohen-Kaminsky, S.2    Truffault, F.3
  • 92
    • 0031892090 scopus 로고    scopus 로고
    • A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes
    • Gunn MD, Tangemann K, Tam C, Cyster JG, Rosen SD, Williams LT. A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes. Proc Natl Acad Sci USA 1998;95(1): 258-263.
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.1 , pp. 258-263
    • Gunn, M.D.1    Tangemann, K.2    Tam, C.3    Cyster, J.G.4    Rosen, S.D.5    Williams, L.T.6
  • 93
    • 24944583626 scopus 로고    scopus 로고
    • Chemokine receptor CCR7 guides T-cell exit from peripheral tissues and entry into afferent lymphatics
    • Bromley SK, Thomas SY, Luster AD. Chemokine receptor CCR7 guides T-cell exit from peripheral tissues and entry into afferent lymphatics. Nat Immunol 2005;6(9):895-901.
    • (2005) Nat Immunol , vol.6 , Issue.9 , pp. 895-901
    • Bromley, S.K.1    Thomas, S.Y.2    Luster, A.D.3
  • 94
    • 0027315862 scopus 로고
    • Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T-cell adhesion to endothelial cells
    • Taub DD, Lloyd AR, Conlon K, Wang JM, Ortaldo JR, Harada A, Matsushima K, Kelvin DJ, Oppenheim JJ. Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T-cell adhesion to endothelial cells. J Exp Med 1993;177(6):1809-1814.
    • (1993) J Exp Med , vol.177 , Issue.6 , pp. 1809-1814
    • Taub, D.D.1    Lloyd, A.R.2    Conlon, K.3    Wang, J.M.4    Ortaldo, J.R.5    Harada, A.6    Matsushima, K.7    Kelvin, D.J.8    Oppenheim, J.J.9
  • 95
    • 61349166620 scopus 로고    scopus 로고
    • CXCL10 and autoimmune diseases
    • Lee EY, Lee ZH, Song YW. CXCL10 and autoimmune diseases. Autoimmun Rev 2009;8(5):379-383.
    • (2009) Autoimmun Rev , vol.8 , Issue.5 , pp. 379-383
    • Lee, E.Y.1    Zh, L.2    Song, Y.W.3
  • 97
    • 0038784523 scopus 로고    scopus 로고
    • A high endothelial venule secretory protein, mac25/angiomodulin, interacts with multiple high endothelial venule-associated molecules including chemokines
    • Nagakubo D, Murai T, Tanaka T, Usui T, Matsumoto M, Sekiguchi K, Miyasaka M. A high endothelial venule secretory protein, mac25/angiomodulin, interacts with multiple high endothelial venule-associated molecules including chemokines. J Immunol 2003;171(2):553-561.
    • (2003) J Immunol , vol.171 , Issue.2 , pp. 553-561
    • Nagakubo, D.1    Murai, T.2    Tanaka, T.3    Usui, T.4    Matsumoto, M.5    Sekiguchi, K.6    Miyasaka, M.7
  • 98
    • 43949129105 scopus 로고    scopus 로고
    • Reciprocal cross-talk between RANKL and interferon-gamma-inducible protein 10 is responsible for bone-erosive experimental arthritis
    • Kwak HB, Ha H, Kim HN, Lee JH, Kim HS, Lee S, Kim HM, Kim JY, Kim HH, Song YW, Lee ZH. Reciprocal cross-talk between RANKL and interferon-gamma- inducible protein 10 is responsible for bone-erosive experimental arthritis. Arthritis Rheum 2008;58(5):1332-1342.
    • (2008) Arthritis Rheum , vol.58 , Issue.5 , pp. 1332-1342
    • Kwak, H.B.1    Ha, H.2    Kim, H.N.3    Lee, J.H.4    Kim, H.S.5    Lee, S.6    Kim, H.M.7    Kim, J.Y.8    Kim, H.H.9    Song, Y.W.10    Zh, L.11
  • 100
    • 44849090702 scopus 로고    scopus 로고
    • Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input
    • White AJ, Withers DR, Parnell SM, Scott HS, Finke D, Lane PJ, Jenkinson EJ, Anderson G. Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input. Eur J Immunol 2008; 38(4):942-947.
    • (2008) Eur J Immunol , vol.38 , Issue.4 , pp. 942-947
    • White, A.J.1    Withers, D.R.2    Parnell, S.M.3    Scott, H.S.4    Finke, D.5    Lane, P.J.6    Jenkinson, E.J.7    Anderson, G.8
  • 101
    • 0034536820 scopus 로고    scopus 로고
    • Chemokines define distinct microenvironments in the developing thymus
    • Bleul CC, Boehm T. Chemokines define distinct microenvironments in the developing thymus. Eur J Immunol 2000;30(12):3371-3379.
    • (2000) Eur J Immunol , vol.30 , Issue.12 , pp. 3371-3379
    • Bleul, C.C.1    Boehm, T.2
  • 102
    • 17644365138 scopus 로고    scopus 로고
    • Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs
    • Cyster JG. Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs. Annu Rev Immunol 2005;23:127-159.
    • (2005) Annu Rev Immunol , vol.23 , pp. 127-159
    • Cyster, J.G.1
  • 105
    • 0142149043 scopus 로고    scopus 로고
    • Critical role for CXCR4 signaling in progenitor localization and T-cell differentiation in the postnatal thymus
    • Plotkin J, Prockop SE, Lepique A, Petrie HT. Critical role for CXCR4 signaling in progenitor localization and T-cell differentiation in the postnatal thymus. J Immunol 2003; 171(9):4521-4527.
    • (2003) J Immunol , vol.171 , Issue.9 , pp. 4521-4527
    • Plotkin, J.1    Prockop, S.E.2    Lepique, A.3    Petrie, H.T.4
  • 106
    • 0034650922 scopus 로고    scopus 로고
    • Murine CCR9, a chemokine receptor for thymus-expressed chemokine that is up-regulated following pre-TCR signaling
    • Norment AM, Bogatzki LY, Gantner BN, Bevan MJ. Murine CCR9, a chemokine receptor for thymus-expressed chemokine that is up-regulated following pre-TCR signaling. J Immunol 2000;164(2):639-648.
    • (2000) J Immunol , vol.164 , Issue.2 , pp. 639-648
    • Norment, A.M.1    Bogatzki, L.Y.2    Gantner, B.N.3    Bevan, M.J.4
  • 107
    • 0033214322 scopus 로고    scopus 로고
    • TECK, an efficacious chemoattractant for human thymocytes, uses GPR-9-6/CCR9 as a specific receptor
    • Youn BS, Kim CH, Smith FO, Broxmeyer HE. TECK, an efficacious chemoattractant for human thymocytes, uses GPR-9-6/CCR9 as a specific receptor. Blood 1999;94(7): 2533-2536.
    • (1999) Blood , vol.94 , Issue.7 , pp. 2533-2536
    • Youn, B.S.1    Kim, C.H.2    Smith, F.O.3    Broxmeyer, H.E.4
  • 108
    • 0034235746 scopus 로고    scopus 로고
    • Macrophage-derived chemokine and EBI1-ligand chemokine attract human thymocytes in different stage of development and are produced by distinct subsets of medullary epithelial cells: Possible implications for negative selection
    • Annunziato F, Romagnani P, Cosmi L, Beltrame C, Steiner BH, Lazzeri E, Raport CJ, Galli G, Manetti R, Mavilia C, Vanini V, Chantry D, Maggi E, Romagnani S. Macrophage-derived chemokine and EBI1-ligand chemokine attract human thymocytes in different stage of development and are produced by distinct subsets of medullary epithelial cells: Possible implications for negative selection. J Immunol 2000;165(1):238-246.
    • (2000) J Immunol , vol.165 , Issue.1 , pp. 238-246
    • Annunziato, F.1    Romagnani, P.2    Cosmi, L.3    Beltrame, C.4    Steiner, B.H.5    Lazzeri, E.6    Raport, C.J.7    Galli, G.8    Manetti, R.9    Mavilia, C.10    Vanini, V.11    Chantry, D.12    Maggi, E.13    Romagnani, S.14
  • 109
    • 1642289268 scopus 로고    scopus 로고
    • CCR7 directs the migration of thymocytes into the thymic medulla
    • Kwan J, Killeen N. CCR7 directs the migration of thymocytes into the thymic medulla. J Immunol 2004; 172(7):3999-4007.
    • (2004) J Immunol , vol.172 , Issue.7 , pp. 3999-4007
    • Kwan, J.1    Killeen, N.2
  • 113
    • 26044480408 scopus 로고    scopus 로고
    • A CXCR4-dependent chemorepellent signal contributes to the emigration of mature single-positive CD4 cells from the fetal thymus
    • Vianello F, Kraft P, Mok YT, Hart WK, White N, Poznansky MC. A CXCR4-dependent chemorepellent signal contributes to the emigration of mature single-positive CD4 cells from the fetal thymus. J Immunol 2005;175(8): 5115-5125.
    • (2005) J Immunol , vol.175 , Issue.8 , pp. 5115-5125
    • Vianello, F.1    Kraft, P.2    Mok, Y.T.3    Hart, W.K.4    White, N.5    Poznansky, M.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.