Generation of Human Embryonic Stem Cell Reporter Lines Expressing GFP Specifically in Neural Progenitors

Stem Cell Reviews and Reports

Volumn 6, Issue 3, 2010, Pages 438-449

  Noisa, Parinya ^a   Urrutikoetxea Uriguen, Alai ^a   Li, Meng ^a   Cui, Wei ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

GFP reporter; Human embryonic stem cells; Nestin; Neural differentiation; Neural progenitor

Indexed keywords

GREEN FLUORESCENT PROTEIN; INTERMEDIATE FILAMENT PROTEIN; NERVE PROTEIN; NESTIN;

CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; CYTOLOGY; EMBRYONIC STEM CELL; GENETICS; HUMAN; METABOLISM; NERVE CELL; PHYSIOLOGY; REPORTER GENE; REVIEW;

CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; EMBRYONIC STEM CELLS; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HUMANS; INTERMEDIATE FILAMENT PROTEINS; NERVE TISSUE PROTEINS; NEURONS;

EID: 77955853858     PISSN: 15508943     EISSN: 15586804     Source Type: Journal    
DOI: 10.1007/s12015-010-9159-9     Document Type: Review

References (34)

1. Thomson, J. A., Itskovitz-Eldor, J., Shapiro, S. S., et al. (1998). Embryonic stem cell lines derived from human blastocysts. Science, 282(5391), 1145-1147.
2. Daley, G. Q., & Scadden, D. T. (2008). Prospects for stem cell-based therapy. Cell, 132(4), 544-548.
3. Dvash, T., & Benvenisty, N. (2004). Human embryonic stem cells as a model for early human development. Best Pratice and Research Clinical Obstetrics and Gynaecology, 18(6), 929-940.
4. Okada, Y., Matsumoto, A., Shimazaki, T., et al. (2008). Spatiotemporal recapitulation of central nervous system development by murine embryonic stem cell-derived neural stem/progenitor cells. Stem Cells, 26(12), 3086-3098.
5. Aubert, J., Stavridis, M. P., Tweedie, S., et al. (2003). Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1-gfp knock-in mice. Proceedings of the National Academy of Sciences of the United States of America, 100(Suppl 1), 11836-11841.
6. Ganat, Y. M., Silbereis, J., Cave, C., et al. (2006). Early postnatal astroglial cells produce multilineage precursors and neural stem cells in vivo. Journal of Neuroscience, 26(33), 8609-8621.
7. Kawaguchi, A., Miyata, T., Sawamoto, K., et al. (2001). Nestin-EGFP transgenic mice: visualization of the self-renewal and multipotency of CNS stem cells. Molecular and Cellular Neurosciences, 17(2), 259-273.
8. Pratt, T., Sharp, L., Nichols, J., Price, D. J., & Mason, J. O. (2000). Embryonic stem cells and transgenic mice ubiquitously expressing a tau-tagged green fluorescent protein. Developments in Biologicals, 228(1), 19-28.
9. Zhao, S., Maxwell, S., Jimenez-Beristain, A., et al. (2004). Generation of embryonic stem cells and transgenic mice expressing green fluorescence protein in midbrain dopaminergic neurons. The European Journal of Neuroscience, 19(5), 1133-1140.
10. Placantonakis, D. G., Tomishima, M. J., Lafaille, F., et al. (2009). BAC transgenesis in human embryonic stem cells as a novel tool to define the human neural lineage. Stem Cells, 27(3), 521-532.
11. Xue, H., Wu, S., Papadeas, S. T., et al. (2009). A targeted neuroglial reporter line generated by homologous recombination in human embryonic stem cells. Stem Cells, 27(8), 1836-1846.
12. Lendahl, U., Zimmerman, L. B., & McKay, R. D. (1990). CNS stem cells express a new class of intermediate filament protein. 60(4), Cell, 585-595.
13. Mujtaba, T., Mayer-Proschel, M., & Rao, M. S. (1998). A common neural progenitor for the CNS and PNS. Developments in Biologicals, 200(1), 1-15.
14. Lothian, C., & Lendahl, U. (1997). An evolutionarily conserved region in the second intron of the human nestin gene directs gene expression to CNS progenitor cells and to early neural crest cells. The European Journal of Neuroscience, 9(3), 452-462.
15. Lothian, C., Prakash, N., Lendahl, U., & Wahlstrom, G. M. (1999). Identification of both general and region-specific embryonic CNS enhancer elements in the nestin promoter. Experimental Cell Research, 248(2), 509-519.
16. Zimmerman, L., Parr, B., Lendahl, U., et al. (1994). Independent regulatory elements in the nestin gene direct transgene expression to neural stem cells or muscle precursors. Neuron, 12(1), 11-24.
17. Gerrard, L., Zhao, D., Clark, A. J., & Cui, W. (2005). Stably transfected human embryonic stem cell clones express OCT4-specific green fluorescent protein and maintain self-renewal and pluripotency. Stem Cells, 23(1), 124-133.
18. Xu, C., Inokuma, M. S., Denham, J., et al. (2001). Feeder-free growth of undifferentiated human embryonic stem cells. Nature Biotechnology, 19(10), 971-974.
19. Itskovitz-Eldor, J., Schuldiner, M., Karsenti, D., et al. (2000). Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers. Molecular Medicine, 6(2), 88-95.
20. Gerrard, L., Rodgers, L., & Cui, W. (2005). Differentiation of human embryonic stem cells to neural lineages in adherent culture by blocking bone morphogenetic protein signaling. Stem Cells, 23(9), 1234-1241.
21. Kioussis, D., & Festenstein, R. (1997). Locus control regions: overcoming heterochromatin-induced gene inactivation in mammals. Current Opinion in Genetics and Development, 7(5), 614-619.
22. Pera, M. F., Andrade, J., Houssami, S., et al. (2004). Regulation of human embryonic stem cell differentiation by BMP-2 and its antagonist noggin. Journal of Cell Science, 117(Pt 7), 1269-1280.
23. Xu, R. H., Chen, X., Li, D. S., et al. (2002). BMP4 initiates human embryonic stem cell differentiation to trophoblast. Nature Biotechnology, 20(12), 1261-1264.
24. Jin, Z., Liu, L., Bian, W., et al. (2009). Different transcription factors regulate nestin gene expression during P19 cell neural differentiation and central nervous system development. Journal of Biological Chemistry 284(12), 8160-8173.
25. Tanaka, S., Kamachi, Y., Tanouchi, A., Hamada, H., Jing, N., & Kondoh, H. (2004). Interplay of SOX and POU factors in regulation of the Nestin gene in neural primordial cells. Molecular and Cellular Biology, 24(20), 8834-8846.
26. Yasuhara, N., Shibazaki, N., Tanaka, S., et al. (2007). Triggering neural differentiation of ES cells by subtype switching of importin-alpha. Nature Cell Biology, 9(1), 72-79.
27. Wu, J. Q., Habegger, L., Noisa, P., et al. (2010). Dynamic transcriptomes during neural differentiation of human embryonic stem cells revealed by short, long, and paired-end sequencing. Proceedings of the National Academy of Sciences of the United States of America, 107(11), 5254-5259.
28. Johansson, C. B., Lothian, C., Molin, M., Okano, H., & Lendahl, U. (2002). Nestin enhancer requirements for expression in normal and injured adult CNS. Journal of Neuroscience Research, 69(6), 784-794.
29. Lenka, N., Lu, Z. J., Sasse, P., Hescheler, J., & Fleischmann, B. K. (2002). Quantitation and functional characterization of neural cells derived from ES cells using nestin enhancer-mediated targeting in vitro. Journal of Cell Science, 115(Pt 7), 1471-1485.
30. Boyer, L. A., Lee, T. I., Cole, M. F., et al. (2005). Core transcriptional regulatory circuitry in human embryonic stem cells. Cell, 122(6), 947-956.
31. Chambers, I., & Tomlinson, S. R. (2009). The transcriptional foundation of pluripotency. Development, 136(14), 2311-2322.
32. Kondoh, H., & Kamachi, Y. (2010). SOX-partner code for cell specification: Regulatory target selection and underlying molecular mechanisms. The International Journal of Biochemistry and Cell Biology, 42(3), 391-399.
33. Giudice, A., & Trounson, A. (2008). Genetic modification of human embryonic stem cells for derivation of target cells. Cell Stem Cell, 2(5), 422-433.
34. Alami, R., Greally, J. M., Tanimoto, K., et al. (2000). Beta-globin YAC transgenes exhibit uniform expression levels but position effect variegation in mice. Human Molecular Genetics, 9(4), 631-636.