Prevalence of celiac disease and symptoms in relatives of patients with celiac disease

European Review for Medical and Pharmacological Sciences

Volumn 14, Issue 6, 2010, Pages 567-572

  Tursi, A ^a   Elisei, W ^b   Giorgetti, G M ^c   Gaspardone, A ^c   Lecca, P G ^d   Cesare, L D I ^d   Brandimarte, G ^d  

^a ASL BAT   (Italy)

^b ASL RMH   (Italy)

^c S EUGENIO HOSPITAL   (Italy)

^d Cristo Re Hospital   (Italy)

Author keywords

Celiac disease; Family members; Prevalence; Symptoms

Indexed keywords

ABDOMINAL PAIN; ADULT; ALOPECIA; ARTICLE; CELIAC DISEASE; CHILD; CLINICAL FEATURE; COHORT ANALYSIS; DIARRHEA; DOWN SYNDROME; FAMILY ASSESSMENT; FATIGUE; FEMALE; GASTROESOPHAGEAL REFLUX; HASHIMOTO DISEASE; HEADACHE; HIGH RISK POPULATION; HUMAN; IMMUNOGLOBULIN A DEFICIENCY; INFANT; INSULIN DEPENDENT DIABETES MELLITUS; IRON DEFICIENCY ANEMIA; MAJOR CLINICAL STUDY; MALABSORPTION; MALE; MUSCULOSKELETAL PAIN; PRESCHOOL CHILD; PSORIASIS; RECURRENT ABORTION; RELATIVE; SCHOOL CHILD; THYROID DISEASE; WEIGHT REDUCTION; ADOLESCENT; AGED; FAMILY; GENETICS; MIDDLE AGED; PREVALENCE; VERY ELDERLY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CELIAC DISEASE; CHILD; CHILD, PRESCHOOL; FAMILY; FEMALE; HUMANS; MALE; MIDDLE AGED; PREVALENCE;

EID: 77955829902     PISSN: 11283602     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. ROSTOM A, MURRAY JA, KAGNOFF MF. American Gastroenterological Association (AGA) Institute technical review on the diagnosis and management of celiac disease. Gastroenterology 2006; 131: 1981-2002. (Pubitemid 44958523)
2. CATASSI C. The world map of celiac disease. Acta Gastroenterol Latinoam 2005; 35: 37-55.
3. FASANO A, BERTI I, GERARDUZZI T, NOT T, COLLETTI RB, DRAGO S, ELITSUR Y, GREEN PH, GUANDALINI S, HILL ID, PIETZAK M, VENTURA A, THORPE M, KRYSZAK D, FORNAROLI F, WASSERMAN SS, MURRAY JA, HORVATH K. Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study. Arch Intern Med 2003; 163: 286-292.
4. BOOK L, ZONE JJ, NEUHAUSEN L. Prevalence of celiac disease among relatives of sib pairs with celiac disease in US families. Am J Gastroenterol 2003; 98: 377-381.
5. GUDJONSDOTTIR AH, NILSSON S, EK J, KRISTIANSSON B, ASCHER H. The risk of celiac disease in 107 families with at least two affected siblings. J Pediatr Gastroenterol Nutr 2004; 38: 338-342.
6. GRECO L, ROMINO R, COTO I, DI COSMO N, PERCOPO S, MAGLIO M, PAPARO F, GASPERI V, LIMONGELLI MG, COTICHINI R, D'AGATE C, TINTO N, SACCHETTI L, TOSI R, STAZI MA. The first large population based twin study of celiac disease. Gut 2002; 50: 624-628. (Pubitemid 34407487)
7. FEIGHERY C, WEIR DG, WHELAN A, WILLOUGHBY R, YOUNGPRAPAKORN S, LYNCH S, O'MORÁIN C, MCENEANY P, O'FARRELLY C. Diagnosis of glutensensitive enteropathy: is exclusively reliance on histology appropriate? Eur J Gastroenterol Hepatol 1998; 10: 919-925.
8. MARSH MN. Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ("celiac sprue"). Gastroenterology. 1992; 102: 330-354.
9. ROSTAMI K, KECKHAERT J, TIEMESSEN R, VON BLOMBERG BM, MEIJER JW, MULDER CJ. Sensitivity of anti-endomysium and anti-gliadin antibodies in untreated celiac disease: disappointing in clinical practice. Am J Gastroenterol 1999; 94: 888-894.
10. HAYAT M, CAIMS A, DIXON MF, O'MAHONEY S. Quantitation of intraepithelial lymphocytes in human duodenum; what is normal? J Clin Pathol 2002; 55: 393-394.
11. DICKSON BC, STREUTKER CJ, CHETTY R. Coeliac disease: an update for pathologists. J Clin Pathol 2006; 59: 1008-1016.
12. OBERHUBER G, GRANDITSCH G, VOGELSANG H. The histopathology of coeliac disease: time for a standardized report scheme for pathologists. Eur J Gastroenterol Hepatol 1999; 11: 1185-1194.
13. ALMEIDA PL, GANDOLFI L, MODELLI IC, MARTINS RDE C, ALMEIDA RC, PRATESI R. Prevalence of celiac disease among first degree relatives of Brazilian celiac patients. Arq Gastroenterol 2008; 45: 69-72.
14. RUBIO-TAPIA A, VAN DYKE CT, LAHR BD, ZINSMEISTER AR, EL-YOUSSEF M, MOORE SB, BOWMAN M, BURGART LJ, MELTON LJ 3RD, MURRAY JA. Predictors of family risk for celiac disease: a population-based study. Clin Gastroenterol Hepatol 2008; 6: 983-987.
15. DUBÉ C, ROSTOM A, SY R, CRANNEY A, SALOOJEE N, GARRITTY C, SAMPSON M, ZHANG L, YAZDI F, MAMALADZE V, PAN I, MACNEIL J, MACK D, PATEL D, MOHER D. The prevalence of celiac disease in average-risk and at-risk Western European Population: a systematic review. Gastroenterology 2005; 128: S57-67.
16. MURRAY JA. Celiac disease in patients with an affected member, type 1 diabetes, iron-deficiency, or osteoporosis. Gastroenterology 2005; 128(Suppl 1): S52-56.
17. BIAGI F, CAMPANELLA J, BIANCHI PI, ZANELLATI G, CAPRIGLIONE I, KLERSY C, CORAZZA GR. The incidence of coeliac disease in adult first degree relatives. Dig Liver Dis 2008; 40: 97-100.
18. TURSI A, BRANDIMARTE G, GIORGETTI G, GIGLIOBIANCO A, LOMBARDI D, GASBARRINI G. Low prevalence of antigliadin and anti-endomysium antibodies in subclinical/silent celiac disease. Am J Gastroenterol 2001; 96: 1507-1510. (Pubitemid 32455082)
19. ABRAMS JA, DIAMOND B, ROTTERDAM H, GREEN PH. Seronegative celiac disease: increased prevalence with lesser degrees of villous atrophy. Dig Dis Sci 2004; 49: 546-550.
20. THOMAS HJ, AHMAD T, RAJAGURU C, BARNARDO M, WARREN BF, JEWELL DP. Contribution of histological, serological, and genetic factors to the clinical heterogeneity of adult-onset coeliac disease. Scand J Gastroenterol 2009; 10: 1-8.
21. MEGIORNI F, MORA B, BONAMICO M, BARBATO M, MONTUORI M, VIOLA F, TRABACE S, MAZZILLI MC. HLA-DQ and susceptibility to celiac disease: evidence for gender differences and parent-of-origin effects. Am J Gastroenterol 2008; 103: 997-1003.
22. DI SABATINO A, CORAZZA GR. Coeliac disease. Lancet 2009; 373: 1480-1493.
23. TURSI A. Can histological damage influence the severity of celiac disease? An unanswered question. Dig Liver Dis 2007; 39: 30-32.
24. TURSI A, ELISEI W, GIORGETTI GM, BRANDIMARTE G, AIELLO F. Complications in celiac disease under gluten-free diet. Dig Dis Sci 2009; 54: 2175-2182.
25. CUOCO L, CERTO M, JORIZZO RA, DE VITIS I, TURSI A, PAPA A, DE MARINIS L, FEDELI P, FEDELI G, GASBARRINI G. Prevalence and early diagnosis of coeliac disease in autoimmune thyroid disorders. Ital J Gastroenterol Hepatol 1999; 31: 283-287.
26. PETAROS P, MARTELOSSI S, TOMMASINI A, TORRE G, CARADONNA M, VENTURA A. Prevalence of autoimmune disorders in relatives of patients with celiac disease. Dig Dis Sci 2002; 47: 1427-1431. (Pubitemid 34753916)
27. NEUHAUSEN LA, STEELE L, RYAN S, MOUSAVI M, PINTO M, OSANN KE, FLODMAN P, ZONE JJ. Co-occurrence of celiac disease and other autoimmune diseases in celiacs and their first-degree relatives. J Autoimmunity 2008; 31: 160-165.
28. CHANG M, GREEN PRH. Genetic testing before serologic screening in relatives of patients with celiac disease as a cost containment method. J Clin Gastroenterol 2009; 43: 43-50.
29. NIVELONI S, PEDREIRA S, SUGAI E, VAZQUEZ H, SMECUOL E, FIORINI A, CABANNE A, DEZI R, VALERO J, KOGAN Z, MAURINO E, BAI JC. The natural history of gluten sensitivity: report of two new celiac disease patients resulting from a long-term follow-up of nonatrophic, first-degree relatives. Am J Gastroenterol 2000; 95: 463-468.
30. HÖGBERG L, FÄLTH-MAGNUSSON K, GRODZINSKY E, STENHAMMAR L. Familial prevalence of coeliac disease: a twenty-year follow-up study. Scand J Gastroenterol 2003; 38: 61-65.
31. PITTSCHIELER K, GENTILI L, NIEDERHOFER H. Onset of coeliac disease: a prospective longitudinal study. Acta Paediatr 2003; 92: 1149-1152. (Pubitemid 37297093)
32. GOLDBERG D, KRYSZAK D, FASANO A, GREEN PH. Screening for celiac disease in family members: is follow-up testing necessary? Dig Dis Sci 2007; 52: 1082-1086.