Effect of single dose administration of Polyalthia longifolia (Sonn.) Thw. var. pendula leaf on gross behavioral assessment in mice

Indian Drugs

Volumn 46, Issue 2, 2009, Pages 116-123

  Nair, R ^a   Shukla, V ^a   Chanda, S ^a  

^a NONE

Author keywords

Acute toxicity; Gross behavioral studies; Polyalthia longifolia

Indexed keywords

PLANT EXTRACT; POLYALTHIA LONGIFOLIA EXTRACT; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG SAFETY; FEMALE; MALE; MOUSE; NONHUMAN; PLANT LEAF; POLYALTHIA; POLYALTHIA LONGIFOLIA; SINGLE DRUG DOSE; TOXICITY TESTING;

EID: 77955827750     PISSN: 0019462X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Klein R, Toxicology and Herbs: An Introduction, Aust J Med Herbalism, 8 (1996) 100.
2. University of Wisconsin Chemical Safety and Disposal Guide (UWCSDG), Chemical and Environmental Safety Program, University of Wisconsin-Madison, 30 N. Murray St.,Madison, WI. 53715-2609 (1999).
3. Erik W, Acute Oral Toxicity, Environ Health Perspect, Supplement 2, 106 (1998) 497.
4. Guidance for Industry, Single dose acute toxicity testing for pharmaceuticals, Center for Drug Evaluation and Research (CDER), (1996) 1.
5. Sofowora E A, Medicinal Plants and Traditional Medicine in Africa. Spectrum Books Ltd. Ibadan, Nigeria (1989).
6. Zhu M, Lew K T & Leung P, Protective effects of plant formula on ethanol induced gastric lesions in rats, Phytother Res 16 (2002) 276.
7. Cristiani B, Doris R F, Dórys A C, de Borba Batschauer A P, Valdir C F & Adair R S S, Acute and subacute toxicity of the hydroalcoholic extract from Wedelia paludosa (Acmela brasiliensis), J Pharm Pharmaceut Sci, 8 (2005) 370.
8. Stanley O A, Florence C N, David D A, Gloria A A, Sunday D, Kazeem S I, Matthew D, Patrick E C N, Charles W & Karynius G, Toxicity studies in rats fed nature cure bitters, African J Biotechnol, 4 (2005) 72.
9. Kishore N, Dubey N K, Tripathi R D & Singh S K, Fungitoxic activity of leaves of some higher plants, Nat Acad Sci Lett, 6 (1982) 9.
10. Faizi S, Mughal N R, Khan R A, Khan S A, Ahmad A, Bibi N & Ahmed S A, Evaluation of the antimicrobial property of Polyalthia longifolia var. pendula: isolation of a lactone as the active antibacterial agent from the ethanol extract of the stem, Phytother Res, 17 (2003) 1177.
11. Marthanda M, Subramanyam M, Hima Bindu M & Annapurna J, Antibacterial activity of clerodane diterpenoids from Polyalthia longifolia seeds, Fitoterapia, 76 (2005) 3.
12. Nair R & Chanda S, Evaluation of Polyalthia longifolia (Sonn.) leaf extract for antifungal activity, J Cell Tissue Res, 6 (2006) 581.
13. Nair R, Shukla V & Chanda S, Assessment of Polyalthia longifolia var. pendula for hypoglycemic and anthihyperglycemic activity, J Clin Dlagn Res, 1 (2007) 1.
14. Nair R & Chanda S, Antimicrobial activity of Polyalthia longifolia (Sonn.) Thw. Var. pendula leaf extracts against 91 clinically important pathogenic microbial strains. J Herbal Pharmacotherapy, (2008) (In Press)
15. Tanna A, Nair R & Chanda S, Assessment of anti-inflammatory and hepatoprotective potency of Polyalthia longifolia var. pendula leaf in Wistar albino rats, J Nat Med, (2008) (In Press)
16. Paget G E, Barnes J M, In: Evaluation of drug activities. Pharmacometrics, Lawrence DR, Bachrach AL (Eds.) Vol. 1, Academic press, New York (1964).
17. Morpugo C, A new design for the screening of CNS-active drugs in mice Arzneim-Forsch, 11 (1971) 1727.
18. 50, J Appl Toxicol, 6 (1986) 145.