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Volumn 85, Issue 3, 2010, Pages 251-256

MDM2 SNP309 promoter polymorphism, an independent prognostic factor in chronic lymphocytic leukemia

Author keywords

chronic lymphocytic leukemia; MDM2 SNP309; prognostic markers; TP53 mutations

Indexed keywords

CD19 ANTIGEN; CD23 ANTIGEN; CD5 ANTIGEN; PROTEIN MDM2; PROTEIN P53; IMMUNOGLOBULIN HEAVY CHAIN;

EID: 77955824152     PISSN: 09024441     EISSN: 16000609     Source Type: Journal    
DOI: 10.1111/j.1600-0609.2010.01470.x     Document Type: Article
Times cited : (16)

References (26)
  • 4
    • 54049141334 scopus 로고    scopus 로고
    • Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: Results from a detailed genetic characterization with long-term follow-up
    • Zenz T, Kröber A, Scherer K, et al. Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: results from a detailed genetic characterization with long-term follow-up. Blood 2008 112 : 3322 9.
    • (2008) Blood , vol.112 , pp. 3322-9
    • Zenz, T.1    Kröber, A.2    Scherer, K.3
  • 6
    • 0028172868 scopus 로고
    • P53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies
    • Wattel E, Preudhomme C, Hecquet B, Vanrumbeke M, Quesnel B, Dervite I, Morel P, Fenaux P. p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies. Blood 1994 84 : 3148 57.
    • (1994) Blood , vol.84 , pp. 3148-57
    • Wattel, E.1    Preudhomme, C.2    Hecquet, B.3    Vanrumbeke, M.4    Quesnel, B.5    Dervite, I.6    Morel, P.7    Fenaux, P.8
  • 7
    • 61549089361 scopus 로고    scopus 로고
    • The prognostic value of TP53 mutations in chronic lymphocytic leukemia is independent of del17p13: Implications for overall survival and chemorefractoriness
    • Rossi D, Cerri M, Deambrogi C, et al. The prognostic value of TP53 mutations in chronic lymphocytic leukemia is independent of del17p13: implications for overall survival and chemorefractoriness. Clin Cancer Res 2009 15 : 995 1004.
    • (2009) Clin Cancer Res , vol.15 , pp. 995-1004
    • Rossi, D.1    Cerri, M.2    Deambrogi, C.3
  • 8
    • 0037329056 scopus 로고    scopus 로고
    • The p53-Mdm2 module and the ubiquitin system
    • Michael D, Oren M. The p53-Mdm2 module and the ubiquitin system. Semin Cancer Biol 2003 13 : 49 58.
    • (2003) Semin Cancer Biol , vol.13 , pp. 49-58
    • Michael, D.1    Oren, M.2
  • 9
    • 0028081261 scopus 로고
    • The MDM2 oncogene overexpression in chronic lymphocytic leukemia and low-grade lymphoma of B-cell origin
    • Watanabe T, Hotta T, Ichikawa A, Kinoshita T, Nagai H, Uchida T, Murate T, Saito H. The MDM2 oncogene overexpression in chronic lymphocytic leukemia and low-grade lymphoma of B-cell origin. Blood 1994 84 : 3158 65.
    • (1994) Blood , vol.84 , pp. 3158-65
    • Watanabe, T.1    Hotta, T.2    Ichikawa, A.3    Kinoshita, T.4    Nagai, H.5    Uchida, T.6    Murate, T.7    Saito, H.8
  • 10
    • 8844278362 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans
    • Bond GL, Hu W, Bond EE, Robins H, et al. A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. Cell 2004 119 : 591 602.
    • (2004) Cell , vol.119 , pp. 591-602
    • Bond, G.L.1    Hu, W.2    Bond, E.E.3    Robins, H.4
  • 11
    • 0037103257 scopus 로고    scopus 로고
    • Multivariate analysis of prognostic factors in CLL: Clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors
    • Oscier DG, Gardiner AC, Mould SJ, et al. Multivariate analysis of prognostic factors in CLL: clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors. Blood 2002 100 : 1177 84.
    • (2002) Blood , vol.100 , pp. 1177-84
    • Oscier, D.G.1    Gardiner, A.C.2    Mould, S.J.3
  • 12
    • 33847308066 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in the p53 pathway interacts with gender, environmental stresses and tumor genetics to influence in humans
    • Bond GL, Levine AJ. A single nucleotide polymorphism in the p53 pathway interacts with gender, environmental stresses and tumor genetics to influence in humans. Oncogene 2007 26 : 1317 23.
    • (2007) Oncogene , vol.26 , pp. 1317-23
    • Bond, G.L.1    Levine, A.J.2
  • 14
    • 46849101280 scopus 로고    scopus 로고
    • The MDM2-309 TG promoter single nucleotide polymorphism does not alter disease characteristics in chronic lymphocytic leukemia
    • Zenz T, Häbe S, Benner A, Kienle D, Döhner H, Stilgenbauer S. The MDM2-309 TG promoter single nucleotide polymorphism does not alter disease characteristics in chronic lymphocytic leukemia. Haematologica 2008 93 : 1111 3.
    • (2008) Haematologica , vol.93 , pp. 1111-3
    • Zenz, T.1    Häbe, S.2    Benner, A.3    Kienle, D.4    Döhner, H.5    Stilgenbauer, S.6
  • 15
    • 77649181649 scopus 로고    scopus 로고
    • Lack of association between the MDM2 promoter polymorphism SNP309 and clinical outcome in chronic lymphocytic leukemia
    • Kaderi MA, Mansouri M, Zainuddin N, et al. Lack of association between the MDM2 promoter polymorphism SNP309 and clinical outcome in chronic lymphocytic leukemia. Leuk Res 2010 34 : 335 9.
    • (2010) Leuk Res , vol.34 , pp. 335-9
    • Kaderi, M.A.1    Mansouri, M.2    Zainuddin, N.3
  • 16
    • 0024756969 scopus 로고
    • Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction
    • Orita M, Suzuki Y, Sekiya T, Hayashi K. Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction. Genomics 1989 5 : 874 9.
    • (1989) Genomics , vol.5 , pp. 874-9
    • Orita, M.1    Suzuki, Y.2    Sekiya, T.3    Hayashi, K.4
  • 17
    • 9144265458 scopus 로고    scopus 로고
    • Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of BIOMED-2 Concerted Action BMH4-CT98-3936
    • Van Dongen JJM, Lagerak AW, Brüggemann M, et al. Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia 2003 17 : 2257 317.
    • (2003) Leukemia , vol.17 , pp. 2257-317
    • Van Dongen, J.J.M.1    Lagerak, A.W.2    Brüggemann, M.3
  • 18
    • 33744918197 scopus 로고    scopus 로고
    • Association of a functional polymorphism in the promoter of the MDM2 gene with risk of nonsmall cell lung cancer
    • Lind H, Zienolddiny S, Ekstrom PO, Skaug V, Haugen A. Association of a functional polymorphism in the promoter of the MDM2 gene with risk of nonsmall cell lung cancer. Int J Cancer 2006 119 : 718 21.
    • (2006) Int J Cancer , vol.119 , pp. 718-21
    • Lind, H.1    Zienolddiny, S.2    Ekstrom, P.O.3    Skaug, V.4    Haugen, A.5
  • 20
    • 33749040649 scopus 로고    scopus 로고
    • Mdm2 Promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis
    • Ohmiya N, Taguchi A, Mabuchi N, Itoh A, Hirooka Y, Niwa Y, Goto H. Mdm2 Promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis. J Clin Oncol 2006 24 : 4434 40.
    • (2006) J Clin Oncol , vol.24 , pp. 4434-40
    • Ohmiya, N.1    Taguchi, A.2    Mabuchi, N.3    Itoh, A.4    Hirooka, Y.5    Niwa, Y.6    Goto, H.7
  • 21
    • 34547220487 scopus 로고    scopus 로고
    • Mdm2 SNP309 polymorphism as risk factor for susceptibility and poor prognosis in renal cell carcinoma
    • Hirata H, Hinoda Y, Kikuno N, Kawamoto K, Suehiro Y, Tanaka Y, Dahiya R. Mdm2 SNP309 polymorphism as risk factor for susceptibility and poor prognosis in renal cell carcinoma. Clin Cancer Res 2007 13 : 4123 9.
    • (2007) Clin Cancer Res , vol.13 , pp. 4123-9
    • Hirata, H.1    Hinoda, Y.2    Kikuno, N.3    Kawamoto, K.4    Suehiro, Y.5    Tanaka, Y.6    Dahiya, R.7
  • 23
    • 33144460815 scopus 로고    scopus 로고
    • Association between MDM2-SNP309 and age at colorectal cancer diagnosis according to p53 mutation status
    • Menin C, Scaini MC, De Salvo GL, et al. Association between MDM2-SNP309 and age at colorectal cancer diagnosis according to p53 mutation status. J Natl Cancer Inst 2006 98 : 285 8.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 285-8
    • Menin, C.1    Scaini, M.C.2    De Salvo, G.L.3
  • 24
    • 45149100665 scopus 로고    scopus 로고
    • Guidelines for diagnosis and treatment of chronic lymphocytic leukemia: A report from the international workshop on chronic lymphocytic leukemia updating the national cancer institute working group 1996 guidelines
    • Hallek M, Cheson BD, Catovsky D, et al. Guidelines for diagnosis and treatment of chronic lymphocytic leukemia: a report from the international workshop on chronic lymphocytic leukemia updating the national cancer institute working group 1996 guidelines. Blood 2008 111 : 5446 56.
    • (2008) Blood , vol.111 , pp. 5446-56
    • Hallek, M.1    Cheson, B.D.2    Catovsky, D.3
  • 25
    • 33646550549 scopus 로고    scopus 로고
    • MDM2 antagonists activate p53 and synergize with genotoxic drugs in B-cell chronic lymphocytic leukemia cells
    • Coll-Mulet L, Iglesias-Serret D, Santidrián AF, et al. MDM2 antagonists activate p53 and synergize with genotoxic drugs in B-cell chronic lymphocytic leukemia cells. Blood 2006 107 : 4109 14.
    • (2006) Blood , vol.107 , pp. 4109-14
    • Coll-Mulet, L.1    Iglesias-Serret, D.2    Santidrián, A.F.3
  • 26
    • 52649119010 scopus 로고    scopus 로고
    • SNP309 as predictor for sensitivity of CLL cells to the MDM2 inhibitor nutlin-3a
    • Seyfried I, Hofbauer S, Stoecher M, Greil R, Tinhofer I. SNP309 as predictor for sensitivity of CLL cells to the MDM2 inhibitor nutlin-3a. Blood 2008 112 : 2168.
    • (2008) Blood , vol.112 , pp. 2168
    • Seyfried, I.1    Hofbauer, S.2    Stoecher, M.3    Greil, R.4    Tinhofer, I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.