High frequency of hand foot syndrome with capecitabine

Journal of the College of Physicians and Surgeons Pakistan

Volumn 20, Issue 6, 2010, Pages 421-422

  Kamil, Muhammad ^a   Haron, Mubassir ^a   Yosuff, Narazah ^a   Khalid, Imran ^b   Azman, Nizuwan ^a  

^a ADVANCED MEDICAL AND DENTAL INSTITUTE   (Malaysia)

^b Seberang Jaya Hospital   (Malaysia)

Author keywords

Capecitabine; Chemotherapy; Colorectal carcinoma; Hand foot syndrome; Oxaliplatin

Indexed keywords

CAPECITABINE; OXALIPLATIN; UNCLASSIFIED DRUG; XELOX; ANTINEOPLASTIC ANTIMETABOLITE; DEOXYCYTIDINE; FLUOROURACIL; PLATINUM COMPLEX;

ADULT; AGED; ARTICLE; CHI SQUARE TEST; CLINICAL ARTICLE; COLORECTAL CARCINOMA; DRUG SAFETY; HAND FOOT SYNDROME; HUMAN; MONOTHERAPY; MULTIPLE CYCLE TREATMENT; RETROSPECTIVE STUDY; ANALOGS AND DERIVATIVES; CHEMICALLY INDUCED; COLORECTAL NEOPLASMS; CROSS-SECTIONAL STUDY; DRUG COMBINATION; FEMALE; HAND DISEASE; MALE; MIDDLE AGED; SKIN DISEASE; SYNDROME;

ADULT; AGED; ANTIMETABOLITES, ANTINEOPLASTIC; COLORECTAL NEOPLASMS; CROSS-SECTIONAL STUDIES; DEOXYCYTIDINE; DRUG THERAPY, COMBINATION; FEMALE; FLUOROURACIL; FOOT DERMATOSES; HAND DERMATOSES; HUMANS; MALE; MIDDLE AGED; ORGANOPLATINUM COMPOUNDS; SYNDROME;

EID: 77955819981     PISSN: 1022386X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Hoff PM, Ansari R, Batist G, Cox J, Kocha W, Kuperminc M, et al. Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first line treatment in 605 patients with metastatic colorectal cancer: results of a randomized phase III study. J Clin Oncol 2001; 19:2282-92. (Pubitemid 32366981)
2. Cassidy J, Twelves C, Van Custem E, Hoff P, Bajetta E, Boyer M, et al. First-line oral capecitabine therapy in metastatic colorectal cancer: a favourable safety profile compared with intravenous 5-fluorouracil/leucovorin. Ann Oncol 2002; 13:566-75.
3. Bellmunt J, Navarro M, Hidalgo R, Sole LA. Palmar-plantar erythrodysesthesia syndrome associated with short-term continuous infusion (5 days) of 5-fluorouracil. Tumori 1988; 74:329-31.
4. Midgley R, Kerr DJ. Capecitabine: have we got the dose right? Nat Clin Pract Oncol 2009; 6:17-24. Epub 2008 Oct 21.
5. Cassidy J, Twelves C. Effective dose-modification scheme for the management of toxicities with capecitabine therapy: data from metastatic colorectal cancer phase III trials. Ann Oncol 2000; 11 (Suppl 4):62.
6. Lee S, Kim H, Hwang S, Kim Y, Nam S, Kim B. Hand-foot syndrome with scleroderma-like change induced by the oral capecitabine: a case report. Korean J Intern Med 2007; 22:109-12.