Carcinogenesis risk assessment of chemicals using medium-term carcinogenesis bioassays

Asian Pacific Journal of Cancer Prevention

Volumn 11, Issue 1, 2010, Pages 4-6

  Tamano, Seiko ^a  

^a Daiyukai Research Institute for Medical Science   (Japan)

Author keywords

Carcinogenesis screening; Cell proliferation; Mutagenesis; Two year bioassay

Indexed keywords

CARCINOGEN;

ANIMAL; BIOASSAY; CARCINOGEN TESTING; CHEMICALLY INDUCED; DRUG EFFECTS; DRUG SCREENING; EXPERIMENTAL LIVER NEOPLASM; FISCHER 344 RAT; LIVER; MALE; MUTAGEN TESTING; PATHOLOGY; PROCEDURES; RAT; RISK ASSESSMENT; TOXICITY;

ANIMALS; BIOLOGICAL ASSAY; CARCINOGENICITY TESTS; CARCINOGENS; DRUG SCREENING ASSAYS, ANTITUMOR; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MUTAGENICITY TESTS; RATS; RATS, INBRED F344; RISK ASSESSMENT;

EID: 77955813498     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (3)

1. Cooper Jr JA, Saracci R, Cole P (1979). Describing the validity of carcinogen screening tests. Br J Cancer, 39, 87-9.
2. Ito N, Tamano S, Shirai T (2003) A medium-term rat liver bioassay for rapid in vivo detection of carcinogenic potential of chemicals. Cancer Sci, 94, 3-8.
3. Shirai, T., Hirose, M., Ito, N. (1999) Medium-term bioassays in rats for rapid detection of the carcinogenic potential of chemicals. The use of short- and medium-term tests for carcinogens and data on genetic effects in carcinogenic hazard evaluation. D.B. McGregor, J.M. Rice and S. Venitt, eds. IARC Scientific Publications No. 146, IARC, Lyon, 251-272.