Evolution of the uses of rats and mice for assessing carcinogenic risk from chemicals in humans

Asian Pacific Journal of Cancer Prevention

Volumn 11, Issue 1, 2010, Pages 18-

  Ward, Jerrold M ^a  

^a Global VetPathology   (United States)

Author keywords

Carcinogenesis screening; Mode of action analysis; Two year bioassay

Indexed keywords

CARCINOGEN;

ANIMAL; BIOASSAY; CARCINOGEN TESTING; CHEMICALLY INDUCED; DISEASE MODEL; EVOLUTION; EXPERIMENTAL NEOPLASM; HUMAN; MOUSE; PATHOLOGY; PROCEDURES; RAT; RISK ASSESSMENT; TIME; TOXICITY; TRENDS;

ANIMALS; BIOLOGICAL ASSAY; BIOLOGICAL EVOLUTION; CARCINOGENICITY TESTS; CARCINOGENS; DISEASE MODELS, ANIMAL; HUMANS; MICE; NEOPLASMS, EXPERIMENTAL; RATS; RISK ASSESSMENT; TIME FACTORS;

EID: 77955784923     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (3)

1. EPA Guidelines for Carcinogen Risk Assessment. http://cfpub.epa.gov/ncea/cfm/recordisplay.cfm?deid=116283 Holsapple MP et al (2006). Toxicol Sci, 89, 51.
2. Jacobs A, Jacobson-Kram D, (2004). Human carcinogenic risk evaluation. Part III. Assessing cancer hazard and risk in human drug development. Toxicol Sci, 81, 260-2.
3. Ward, JM, (2007). The two-year rodent carcinogenesis bioassay - Will it survive? J Toxicol Pathol, 20, 13-9.