ERP effects of methylphenidate and working memory load in healthy adults during a serial visual working memory task

Neuroscience Letters

Volumn 482, Issue 2, 2010, Pages 172-176

  Studer, Petra ^a   Wangler, Susanne ^a   Diruf, Martin S ^a   Kratz, Oliver ^a   Moll, Gunther H ^a   Heinrich, Hartmut ^a,b  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b Heckscher Klinikum   (Germany)

Author keywords

Encoding; Event related potentials; Memory load; Methylphenidate; Working memory

Indexed keywords

METHYLPHENIDATE; PLACEBO;

ARTICLE; BRAIN REGION; CLINICAL TRIAL; COGNITION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; ELECTROENCEPHALOGRAPHY; EVENT RELATED POTENTIAL; HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; WORKING MEMORY;

EID: 77955775267     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.07.030     Document Type: Article

References (33)

1. Baddeley A. Working memory. Science 1992, 255:556-559.
2. Barnett R., Maruff P., Vance A., Luk E.S., Costin J., Wood C., Pantelis C. Abnormal executive function in attention deficit hyperactivity disorder: the effect of stimulant medication and age on spatial working memory. Psychol Med 2001, 31:1107-1115.
3. Bedard A.C., Jain U., Johnson S.H., Tannock R. Effects of methylphenidate on working memory components: influence of measurement. J Child Psychol Psychiatry 2007, 48:872-880.
4. Elliott R., Sahakian B.J., Matthews K., Bannerjea A., Rimmer J., Robbins T.W. Effects of methylphenidate on spatial working memory and planning in healthy young adults. Psychopharmacology (Berl) 1997, 131:196-206.
5. Geffen G.M., Wright M.J., Green H.J., Gillespie N.A., Smyth D.C., Evans D.M., Geffen L.B. Effects of memory load and distraction on performance and event-related slow potentials in a visuospatial working memory task. J Cogn Neurosci 1997, 9:743-757.
6. Gevins A., Smith M.E., Le J., Leong H., Bennett J., Martin N., McEvoy L., Du R., Whitfield S. High resolution evoked potential imaging of the cortical dynamics of human working memory. Electroencephalogr Clin Neurophysiol 1996, 98:327-348.
7. Gilhooly K.J., Logie R.H. Thinking in working memory. Working memory and thinking. current issues in thinking and reasoning 1998, 1-6. Psychology Press Ltd., East Sussex. K.J. Gilhooly, R.H. Logie (Eds.).
8. Gomarus H.K., Althaus M., Wijers A.A., Minderaa R.B. The effects of memory load and stimulus relevance on the EEG during a visual selective memory search task: an ERP and ERD/ERS study. Clin Neurophysiol 2006, 117:871-884.
9. Jung T.P., Makeig S., Westerfield M., Townsend J., Courchesne E., Sejnowski T.J. Removal of eye activity artifacts from visual event-related potentials in normal and clinical subjects. Clin Neurophysiol 2000, 111:1745-1758.
10. Kobel M., Bechtel N., Weber P., Specht K., Klarhöfer M., Scheffler K., Opwis K., Penner I.K. Effects of methylphenidate on working memory functioning in children with attention deficit/hyperactivity disorder. Eur J Paediatr Neurol 2009, 13:516-523.
11. Kok A. On the utility of P3 amplitude as a measure of processing capacity. Psychophysiology 2001, 38:557-577.
12. Kurscheidt J.C., Peiler P., Behnken A., Abel S., Pedersen A., Suslow T., Deckert J. Acute effects of methylphenidate on neuropsychological parameters in adults with ADHD: possible relevance for therapy. J Neural Transm 2008, 115:357-362.
13. Löw A., Rockstroh B., Cohen R., Hauk O., Berg P., Maier W. Determining working memory from ERP topography. Brain Topogr 1999, 12:39-47.
14. Löw A., Rockstroh B., Harsch S., Berg P., Cohen R. Event-related potentials in a working-memory task in schizophrenics and controls. Schizophr Res 2000, 46:175-186.
15. McEvoy L.K., Smith M.E., Gevins A. Dynamic cortical networks of verbal and spatial working memory: effects of memory load and task practice. Cereb Cortex 1998, 8:563-574.
16. Mecklinger A., Pfeifer E. Event-related potentials reveal topographical and temporal distinct neuronal activation patterns for spatial and object working memory. Brain Res Cogn Brain Res 1996, 4:211-224.
17. Mehta M.A., Calloway P., Sahakian B.J. Amelioration of specific working memory deficits by methylphenidate in a case of adult attention deficit/hyperactivity disorder. J Psychopharmacol 2000, 14:299-302.
18. Mehta M.A., Goodyer I.M., Sahakian B.J. Methylphenidate improves working memory and set-shifting in AD/HD: relationships to baseline memory capacity. J Child Psychol Psychiatry 2004, 45:293-305.
19. Mehta M.A., Owen A.M., Sahakian B.J., Mavaddat N., Pickard J.D., Robbins T.W. Methylphenidate enhances working memory by modulating discrete frontal and parietal lobe regions in the human brain. J Neurosci 2000, 20:RC65.
20. Mohanty A., Gitelman D.R., Small D.M., Mesulam M.M. The spatial attention network interacts with limbic and monoaminergic systems to modulate motivation-induced attention shifts. Cereb Cortex 2008, 18:2604-2613.
21. Morgan H.M., Klein C., Boehm S.G., Shapiro K.L., Linden D.E. Working memory load for faces modulates P300, N170, and N250r. J Cogn Neurosci 2008, 20:989-1002.
22. Pietrzak R.H., Mollica C.M., Maruff P., Snyder P.J. Cognitive effects of immediate-release methylphenidate in children with attention-deficit/hyperactivity disorder. Neurosci Biobehav Rev 2006, 30:1225-1245.
23. Polich J. Updating P300: an integrative theory of P3a and P3b. Clin Neurophysiol 2007, 118:2128-2148.
24. Rhodes S.M., Coghill D.R., Matthews K. Acute neuropsychological effects of methylphenidate in stimulant drug-naive boys with ADHD II-broader executive and non-executive domains. J Child Psychol Psychiatry 2006, 47:1184-1194.
25. Rhodes S.M., Coghill D.R., Matthews K. Methylphenidate restores visual memory, but not working memory function in attention deficit-hyperkinetic disorder. Psychopharmacology (Berl) 2004, 175:319-330.
26. Rubia K., Halari R., Cubillo A., Mohammad A.M., Brammer M., Taylor E. Methylphenidate normalises activation and functional connectivity deficits in attention and motivation networks in medication-naive children with ADHD during a rewarded continuous performance task. Neuropharmacology 2009, 57:640-652.
27. Ruchkin D.S., Berndt R.S., Johnson R., Ritter W., Grafman J., Canoune H.L. Modality-specific processing streams in verbal working memory: evidence from spatio-temporal patterns of brain activity. Brain Res Cogn Brain Res 1997, 6:95-113.
28. Small D.M., Gitelman D., Simmons K., Bloise S.M., Parrish T., Mesulam M.M. Monetary incentives enhance processing in brain regions mediating top-down control of attention. Cereb Cortex 2005, 15:1855-1865.
29. Tannock R., Ickowicz A., Schachar R. Differential effects of methylphenidate on working memory in ADHD children with and without comorbid anxiety. J Am Acad Child Adolesc Psychiatry 1995, 34:886-896.
30. Turner D.C., Blackwell A.D., Dowson J.H., McLean A., Sahakian B.J. Neurocognitive effects of methylphenidate in adult attention-deficit/hyperactivity disorder. Psychopharmacology (Berl) 2005, 178:286-295.
31. Turner D.C., Robbins T.W., Clark L., Aron A.R., Dowson J., Sahakian B.J. Relative lack of cognitive effects of methylphenidate in elderly male volunteers. Psychopharmacology (Berl) 2003, 168:455-464.
32. Volkow N.D., Wang G.J., Fowler J.S., Telang F., Maynard L., Logan J., Gatley S.J., Pappas N., Wong C., Vaska P., Zhu W., Swanson J.M. Evidence that methylphenidate enhances the saliency of a mathematical task by increasing dopamine in the human brain. Am J Psychiatry 2004, 161:1173-1180.
33. Weiss M.D., Weiss J.R. A guide to the treatment of adults with ADHD. J Clin Psychiatry 2004, 65(Suppl. 3):27-37.