Hyperleptinemia positively correlated with metabolic syndrome in renal transplant recipients

Clinical Transplantation

Volumn 24, Issue 4, 2010, Pages

  Lee, Ming Che ^a,b   Lee, Chung Jen ^c   Ho, Guan Jin ^d   Lee, Chia Chi ^c   Shih, Ming Hui ^d   Chou, Kuei Chun ^d   Hsu, Bang Gee ^a,d  

^a TZU CHI UNIVERSITY   (Taiwan)

^b Cancer Center   (Taiwan)

^c TZU CHI COLLEGE OF TECHNOLOGY   (Taiwan)

^d BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

Author keywords

Body fat mass; High sensitive C reactive protein; Kidney transplantation; Leptin; Metabolic syndrome

Indexed keywords

C REACTIVE PROTEIN; CYCLOSPORIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LEPTIN; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RAPAMYCIN; STEROID; TACROLIMUS; TRIACYLGLYCEROL;

ADULT; ARTICLE; BODY FAT DISTRIBUTION; BODY MASS; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GRAFT RECIPIENT; HUMAN; HYPERLEPTINEMIA; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; PREDICTION; PRIORITY JOURNAL; SKINFOLD THICKNESS; TRIACYLGLYCEROL BLOOD LEVEL; WAIST CIRCUMFERENCE;

ADULT; BODY MASS INDEX; FASTING; FEMALE; HUMANS; KIDNEY TRANSPLANTATION; LEPTIN; MALE; METABOLIC SYNDROME X; MIDDLE AGED; TREATMENT OUTCOME; WAIST CIRCUMFERENCE;

EID: 77955767720     PISSN: 09020063     EISSN: 13990012     Source Type: Journal    
DOI: 10.1111/j.1399-0012.2010.01215.x     Document Type: Article

References (31)

1. Alberti KG, Zimmet P, Shaw J. Metabolic syndrome-a new world-wide definition. A Consensus Statement from the International Diabetes Federation. Diabet Med 2006, 23:469.
2. Isomaa B, Almgren P, Tuomi T. Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care 2001, 24:683.
3. Grundy SM, Cleeman JI, Daniels SR. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005, 112:2735.
4. de Vries AP, Bakker SJ, van Son WJ. Metabolic syndrome is associated with impaired long-term renal allograft function; not all component criteria contribute equally. Am J Transplant 2004, 4:1675.
5. Porrini E, Delgado P, Bigo C. Impact of metabolic syndrome on graft function and survival after cadaveric renal transplantation. Am J Kidney Dis 2006, 48:134.
6. Courivaud C, Kazory A, Simula-Faivre D. Metabolic syndrome and atherosclerotic events in renal transplant recipients. Transplantation 2007, 83:1577.
7. Vázquez-Vela ME, Torres N, Tovar AR. White adipose tissue as endocrine organ and its role in obesity. Arch Med Res 2008, 39:715.
8. Farooqi IS, O'Rahilly S. Leptin: a pivotal regulator of human energy homeostasis. Am J Clin Nutr 2009, 89:980S.
9. Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature 1998, 395:763.
10. Teplan V, Schück O, Racek J. Asymmetric dimethylarginine in obesity after renal transplantation. J Ren Nutr 2008, 18:513.
11. Kayacan SM, Yildiz A, Kazancioglu R. The changes in serum leptin, body fat mass and insulin resistance after renal transplantation. Clin Transplant 2003, 17:63.
12. Souza GC, Costa C, Scalco R. Serum leptin, insulin resistance, and body fat after renal transplantation. J Ren Nutr 2008, 18:479.
13. Malyszko J, Malyszko JS, Pawlak K. Correlations between leptin, body composition, bone mineral density, and bone metabolism in kidney transplant recipients. Transplant Proc 2005, 37:2151.
14. Lee CC, Lee RP, Subeq YM. Fasting serum total ghrelin level inversely correlates with metabolic syndrome in hemodialysis patients. Arch Med Res 2008, 39:785.
15. Chowdhury SD, Ghosh T. The upper arm muscle and fat area of Santal children: an evaluation of nutritional status. Acta Paediatr 2009, 98:103.
16. Wang JH, Subeq YM, Tsai WC. Intravenous N-acetylcysteine with saline hydration improves renal function and ameliorates plasma total homocysteine in patients undergoing cardiac angiography. Ren Fail 2008, 30:527.
17. Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 1998, 15:539.
18. Ward HJ. Nutritional and metabolic issues in solid organ transplantation: targets for future research. J Ren Nutr 2009, 19:111.
19. Naganuma T, Uchida J, Kinoshita Y. The prevalence of metabolic syndrome in Japanese renal transplant recipients. Nephrology (Carlton) 2007, 12:413.
20. Cheung CY, Chan HW, Liu YL. Prevalence of metabolic syndrome in Chinese renal transplant recipients. Hong Kong Med J 2008, 14:379.
21. Mancia G, Bousquet P, Elghozi JL. The sympathetic nervous system and the metabolic syndrome. J Hypertens 2007, 25:909.
22. Eikelis N, Schlaich M, Aggarwal A. Interactions between leptin and the human sympathetic nervous system. Hypertension 2003, 41:1072.
23. Kim SK, Kim HJ, Ahn CW. Hyperleptinemia as a robust risk factor of coronary artery disease and metabolic syndrome in type 2 diabetic patients. Endocr J 2008, 55:1085.
24. Tilg H, Moschen AR. Adipocytokines: mediators linking adipose tissue, inflammation and immunity. Nat Rev Immunol 2006, 6:772.
25. Jéquier E, Tappy L. Regulation of body weight in humans. Physiol Rev 1999, 79:451.
26. Baçzkowska T, Soin J, Soluch L. The role of leptin in body mass index increase in renal allograft recipients. Transplant Proc 2000, 32:1331.
27. El Haggan W, Chauveau P, Barthe N. Serum leptin, body fat, and nutritional markers during the six months post-kidney transplantation. Metabolism 2004, 53:614.
28. Koh KK, Quon MJ, Han SH. Differential metabolic effects of pravastatin and simvastatin in hypercholesterolemic patients. Atherosclerosis 2009, 204:483.
29. Chu CH, Lee JK, Lam HC. Atorvastatin does not affect insulin sensitivity and the adiponectin or leptin levels in hyperlipidemic type 2 diabetes. J Endocrinol Invest 2008, 31:42.
30. Usui I, Fujisaka S, Yamazaki K. Telmisartan reduced blood pressure and HOMA-IR with increasing plasma leptin level in hypertensive and type 2 diabetic patients. Diabetes Res Clin Pract 2007, 77:210.
31. de Vinuesa SG, Goicoechea M, Kanter J. Insulin resistance, inflammatory biomarkers, and adipokines in patients with chronic kidney disease: effects of angiotensin II blockade. J Am Soc Nephrol 2006, 17(12 Suppl 3):S206.