Set up and run a thrombolysis service for acute stroke

Practical Neurology

Volumn 10, Issue 3, 2010, Pages 145-151

  Muir, Keith W ^a   Baird, Tracey ^a  

^a SOUTHERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE DISEASE; ARTICLE; ECONOMICS; EVIDENCE BASED MEDICINE; FIBRINOLYTIC THERAPY; HEALTH CARE DELIVERY; HEALTH SERVICE; HUMAN; PATIENT CARE; STROKE;

ACUTE DISEASE; DELIVERY OF HEALTH CARE; EVIDENCE-BASED MEDICINE; HEALTH SERVICES; HUMANS; PATIENT CARE TEAM; STROKE; THROMBOLYTIC THERAPY;

EID: 77955763724     PISSN: 14747758     EISSN: 14747766     Source Type: Journal    
DOI: 10.1136/jnnp.2010.211615     Document Type: Article

References (34)

1. Clinical Effectiveness and Evaluation Unit. National Sentinel Stroke Audit Phase II (clinical audit) 2008. Report for England, Wales and Northern Ireland. London: Royal College of Physicians of London, 2009.
2. Lees KR, Ford GA, Muir KW, et al.; SITS-UK Group. Thrombolytic therapy for acute stroke in the United Kingdom: experience from the safe implementation of thrombolysis in stroke (SITS) register. QJM 2008;101:863-869.
3. Walters MR, Muir KW, Harbison J, et al. Intravenous thrombolysis for acute ischaemic stroke: preliminary experience with recombinant tissue plasminogen activator in the UK. Cerebrovasc Dis 2005;20:438-442.
4. McCormick MT, Reeves I, Baird T, et al. Implementation of a stroke thrombolysis service within a tertiary neurosciences centre in the United Kingdom. QJM 2008;101:291-298.
5. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 1995;333:1581-1587.
6. Ingall TJ, O'Fallon WM, Asplund K, et al. Findings from the reanalysis of the NINDS tissue plasminogen activator for acute ischemic stroke treatment trial. Stroke 2004;35:2418-2424.
7. Saver JL. Number needed to treat estimates incorporating effects over the entire range of clinical outcomes: novel derivation method and application to thrombolytic therapy for acute stroke. Arch Neurol 2004;61:1066-1070.
8. Hacke W, Donnan G, Fieschi C, et al.; ATLANTIS Trials Investigators; ECASS Trials Investigators; NINDS rt-PA Study Group Investigators. Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet 2004;363:768-774.
9. Hacke W, Kaste M, Bluhmki E, et al.; ECASS Investigators. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med 2008;359:1317-1329.
10. Del Zoppo GJ, Saver JL, Jauch EC, et al.; American Heart Association Stroke Council. Expansion of the time window for treatment of acute ischemic stroke with intravenous tissue plasminogen activator: a science advisory from the American Heart Association/American Stroke Association. Stroke 2009;40:2945-2948.
11. Management of Patients with Stroke or TIA: Assessment, Investigation, Immediate Management and Secondary Prevention. A National Clinical Guideline. SIGN Publication No. 108. Edinburgh: Scottish Intercollegiate Guidelines Network, 2008:103.
12. Wahlgren N, Ahmed N, Dávalos A, et al.; SITS investigators. Thrombolysis with alteplase 3-4.5 h after acute ischaemic stroke (SITS-ISTR): an observational study. Lancet 2008;372:1303-1309.
13. Wahlgren N, Ahmed N, Dávalos A, et al.; SITS-MOST investigators. Thrombolysis with alteplase or acuteischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study. Lancet 2007;369:275-282.
14. Whiteley W, Lindley R, Wardlaw J, et al.; IST-3 Collaborative Group. Third international stroke trial. Int J Stroke 2006;1:172-176.
15. Sandercock P, Berge E, Dennis M, et al. Costeffectiveness of thrombolysis with recombinant tissue plasminogen activator for acute ischemic stroke assessed by a model based on UK NHS costs. Stroke 2004;35:1490-1497.
16. Harbison J, Massey A, Barnett L, et al. Rapid ambulance protocol for acute stroke. Lancet 1999;353:1935.
17. Harraf F, Sharma AK, Brown MM, et al. A multicentre observational study of presentation and early assessment of acute stroke. BMJ 2002;325:17.
18. Harbison J, Hossain O, Jenkinson D, et al. Diagnostic accuracy of stroke referrals from primary care, emergency room physicians, and ambulance staff using the face arm speech test. Stroke 2003;34:71-76.
19. Gladstone DJ, Rodan LH, Sahlas DJ, et al. A citywide prehospital protocol increases access to stroke thrombolysis in Toronto. Stroke 2009;40:3841-3844.
20. Audebert HJ, Kukla C, Vatankhah B, et al. Comparison of tissue plasminogen activator administration management between Telestroke Network hospitals and academic stroke centers: the Telemedical Pilot Project for Integrative Stroke Care in Bavaria/Germany. Stroke 2006;37:1822-1827.
21. Audebert HJ, Schultes K, Tietz V, et al.; Telemedical Project for Integrative Stroke Care (TEMPiS). Long-term effects of specialized stroke care with telemedicine support in community hospitals on behalf of the Telemedical Project for Integrative Stroke Care (TEMPiS). Stroke 2009;40:902-908.
22. Vatankhah B, Schenkel J, Fürst A, et al. Telemedically provided stroke expertise beyond normal working hours. The Telemedical Project for Integrative Stroke Care. Cerebrovasc Dis 2008;25:332-337.
23. Nor AM, Davis J, Sen B, et al. The Recognition of Stroke in the Emergency Room (ROSIER) scale: development and validation of a stroke recognition instrument. Lancet Neurol 2005;4:727-734.
24. Libman RB, Wirkowski E, Alvir J, et al. Conditions that mimic stroke in the emergency department. Implications for acute stroke trials. Arch Neurol 1995;52:1119-1122.
25. Wardlaw JM, Seymour J, Cairns J, et al. Immediate computed tomography scanning of acute stroke is cost-effective and improves quality of life. Stroke 2004;35:2477-2483.
26. Barber PA, Zhang J, Demchuk AM, et al. Why are stroke patients excluded from TPA therapy? An analysis of patient eligibility. Neurology 2001;56:1015-1020.
27. Weir NU, Buchan AM. A study of the workload and effectiveness of a comprehensive acute stroke service. J Neurol Neurosurg Psychiatry 2005;76:863-685.
28. Romano JG, Muller N, Merino JG, et al. In-hospital delays to stroke thrombolysis: paradoxical effect of early arrival. Neurol Res 2007;29:664-666.
29. Hill MD, Barber PA, Demchuk AM, et al. Building a "brain attack" team to administer thrombolytic therapy for acute ischemic stroke. CMAJ 2000;162:1589-93.
30. Belvís R, Cocho D, Martí-Fàbregas J, et al. Benefits of a prehospital stroke code system. Feasibility and effi cacy in the fi rst year of clinical practice in Barcelona, Spain. Cerebrovasc Dis 2005;19:96-101.
31. Lindsberg PJ, Häppölä O, Kallela M, et al. Door to thrombolysis: ER reorganization and reduced delays to acute stroke treatment. Neurology 2006;67:334-336.
32. Hill MD, Buchan AM; Canadian Alteplase for Stroke Effectiveness Study (CASES) Investigators. Thrombolysis for acute ischemic stroke: results of the Canadian Alteplase for Stroke Effectiveness Study. CMAJ 2005;172:1307-1312.
33. Sudlow C, Warlow C. Getting the priorities right for stroke care. BMJ 2009;338:b2083.
34. Robbins MS. Right brain: my fi rst tPA. Neurology 2009;73:e9-e10.