메뉴 건너뛰기




Volumn 70, Issue 3, 2010, Pages 335-341

Generic and therapeutic substitutions in the UK: Are they a good thing?

Author keywords

Bioequivalence; Cost minimization analysis; Generic substitution; Therapeutic equivalence; Therapeutic substitution

Indexed keywords

ADRENALIN; AMINOPHYLLINE; ANTACID AGENT; APOMORPHINE; BECLOMETASONE; BECLOMETASONE DIPROPIONATE; BISOPROLOL FUMARATE; BUPRENORPHINE; CARBAMAZEPINE; CARDICOR; CLENIL MODULITE; CYCLOSPORIN A; CYPROTERONE; CYPROTERONE ACETATE; DILTIAZEM; DULOXETINE; ESTRADIOL; FENTANYL; GENERIC DRUG; HORMONE; HUMAN GROWTH HORMONE; INSULIN; LITHIUM; MESALAZINE; MORPHINE; NIFEDIPINE; ORAL CONTRACEPTIVE AGENT; OXYCODONE; PANCREATIN; PHENYTOIN; PROSTAGLANDIN E1; SILDENAFIL; SIMETHICONE; TACROLIMUS; THEOPHYLLINE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 77955741424     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2010.03718.x     Document Type: Review
Times cited : (123)

References (40)
  • 1
    • 77955752461 scopus 로고    scopus 로고
    • House of Commons Committee of Public Accounts. Department of Health: Prescribing costs in primary care. December 2007. Available at. (last accessed 5 July 2010)
    • House of Commons Committee of Public Accounts. Department of Health: Prescribing costs in primary care. December 2007. Available at http://www.parliament.uk/parliamentary-committees/committee-of-public-accounts/ pacpn070117.cfm (last accessed 5 July 2010).
  • 2
    • 77955754646 scopus 로고    scopus 로고
    • Statins: To switch or not to switch?
    • Goldsmith D, Duerden M. Statins: to switch or not to switch? Prescriber 2008 19 : 35 41.
    • (2008) Prescriber , vol.19 , pp. 35-41
    • Goldsmith, D.1    Duerden, M.2
  • 3
    • 33845892767 scopus 로고    scopus 로고
    • Cholesterol lowering in patients with CHD and metabolic syndrome
    • Butler R, Wainwright J. Cholesterol lowering in patients with CHD and metabolic syndrome. Lancet 2007 369 : 27.
    • (2007) Lancet , vol.369 , pp. 27
    • Butler, R.1    Wainwright, J.2
  • 4
    • 77955728903 scopus 로고    scopus 로고
    • National Audit Office. Prescribing costs in primary care. May 2007. Available at. (last accessed 5 July 2010)
    • National Audit Office. Prescribing costs in primary care. May 2007. Available at http://www.nao.org.uk/publications/0607/prescribing-costs-in- primary-c.aspx (last accessed 5 July 2010).
  • 5
    • 84855809357 scopus 로고    scopus 로고
    • Institute for Innovation and Improvement. Available at. (last accessed 5 July 2010)
    • Institute for Innovation and Improvement. NHS Better Care, Better Value Indicators. Available at http://www.productivity.nhs.uk/default.aspx (last accessed 5 July 2010).
    • NHS Better Care, Better Value Indicators
  • 6
    • 77955749672 scopus 로고    scopus 로고
    • National Audit Office. (last accessed 5 July 2010)
    • National Audit Office. Prescribing Savings in 2008. http://www.nao.org. uk/publications/0809/prescribing-savings-in-2008.aspx (last accessed 5 July 2010).
    • Prescribing Savings in 2008
  • 7
    • 77955753583 scopus 로고    scopus 로고
    • Department of Health. June 2007. Available at. (last accessed 5 July 2010)
    • Department of Health. Strategies to achieve cost-effective prescribing: Interim Guidance for Primary Care Trusts. June 2007. Available at http://www.dh.gov.uk/en/Publicationsandstatistics/Publications/ PublicationsPolicyAndGuidance/DH-076350?IdcService=GET-FILE&dID= 143220&Rendition=Web (last accessed 5 July 2010).
    • Strategies to Achieve Cost-effective Prescribing: Interim Guidance for Primary Care Trusts
  • 9
    • 77955739867 scopus 로고    scopus 로고
    • The Association of the British Pharmaceutical Industry. (last accessed 5 July 2010)
    • The Association of the British Pharmaceutical Industry. Generic substitution: patient safety comes first. http://www.abpi.org.uk/press/press- releases-10/050110.asp (last accessed 5 July 2010).
    • Generic Substitution: Patient Safety Comes First
  • 10
    • 2342560204 scopus 로고    scopus 로고
    • Department of Health. Available at. (last accessed 5 July 2010)
    • Department of Health. Building on the best: Choice, responsiveness and equity in the NHS. 2003. Available at http://www.dh.gov.uk/en/Consultations/ Responsestoconsultations/DH-4068391 (last accessed 5 July 2010).
    • (2003) Building on the Best: Choice, Responsiveness and Equity in the NHS
  • 11
    • 84872218156 scopus 로고    scopus 로고
    • (last accessed 5 July 2010)
    • NHS Choices. http://www.nhs.uk/choiceintheNHS/Yourchoices/allaboutchoice/ Pages/Allaboutchoice.aspx (last accessed 5 July 2010).
    • NHS Choices
  • 12
    • 77955756706 scopus 로고    scopus 로고
    • last accessed 5 July 2010
    • One Voice Wales. http://www.onevoicewales.org.uk/news/new-nhs-structure- for-wales (last accessed 5 July 2010).
    • One Voice Wales
  • 13
  • 15
    • 25844453682 scopus 로고    scopus 로고
    • Joint Formulary Committee. London. British Medical Association, Royal Pharmaceutical Society of Great Britain
    • Joint Formulary Committee. British National Formulary No 59. London : British Medical Association, Royal Pharmaceutical Society of Great Britain, 2010.
    • (2010) British National Formulary No 59.
  • 16
    • 0030934989 scopus 로고    scopus 로고
    • Generic inhaled salbutamol versus branded salbutamol. A randomised double-blind study
    • Williamson IJ, Reid A, Monei RD, Fennerty AG, Rimmer EM. Generic inhaled salbutamol versus branded salbutamol. A randomised double-blind study. Postgrad Med J 1997 73 : 156 158.
    • (1997) Postgrad Med J , vol.73 , pp. 156-158
    • Williamson, I.J.1    Reid, A.2    Monei, R.D.3    Fennerty, A.G.4    Rimmer, E.M.5
  • 18
    • 57549093120 scopus 로고    scopus 로고
    • Clinical equivalence of generic and brand-name drugs used in cardiovascular disease: A systematic review and meta-analysis
    • Kesselheim AS, Misono AS, Lee JL, Stedman MR, Brookhart MA, Choudhry NK, Shrank WH. Clinical equivalence of generic and brand-name drugs used in cardiovascular disease: a systematic review and meta-analysis. JAMA 2008 300 : 2514 2526.
    • (2008) JAMA , vol.300 , pp. 2514-2526
    • Kesselheim, A.S.1    Misono, A.S.2    Lee, J.L.3    Stedman, M.R.4    Brookhart, M.A.5    Choudhry, N.K.6    Shrank, W.H.7
  • 20
    • 58149259929 scopus 로고    scopus 로고
    • Patient perception of generic antiepileptic drugs in the Midwestern United States
    • Papsdorf TB, Ablah E, Ram S, Sadler T, Liow K. Patient perception of generic antiepileptic drugs in the Midwestern United States. Epilepsy Behav 2009 14 : 150 153.
    • (2009) Epilepsy Behav , vol.14 , pp. 150-153
    • Papsdorf, T.B.1    Ablah, E.2    Ram, S.3    Sadler, T.4    Liow, K.5
  • 22
    • 0142078725 scopus 로고    scopus 로고
    • Scottish Intercollegiate Guidelines Network. Guideline No 70. Edinburgh. Diagnosis and management of epilepsy in adults
    • Scottish Intercollegiate Guidelines Network. Diagnosis and Management of Epilepsy in Adults. Guideline No 70. Edinburgh : Diagnosis and management of epilepsy in adults, 2003.
    • (2003) Diagnosis and Management of Epilepsy in Adults.
  • 23
    • 77955735110 scopus 로고    scopus 로고
    • Department of Health. March 2005. Available at. (last accessed 5 July 2010)
    • Department of Health. Treatment for epilepsy: generic lamotrigine. March 2005. Available at http://www.dh.gov.uk/en/Healthcare/ Medicinespharmacyandindustry/Prescriptions/DH-4104966 (last accessed 5 July 2010).
    • Treatment for Epilepsy: Generic Lamotrigine
  • 24
    • 77955722246 scopus 로고    scopus 로고
    • Epilepsy Action. Available at. (accessed 5 July 2010)
    • Epilepsy Action. Continuity of drugs. Available at http://www.epilepsy. org.uk/info/drugs-change.html (accessed 5 July 2010).
    • Continuity of drugs
  • 26
    • 33644952525 scopus 로고    scopus 로고
    • European Medicines Agency. November 2004. Available at. (last accessed 5 July 2010)
    • European Medicines Agency. Guideline on similar biological medicinal products. November 2004. Available at http://www.ema.europa.eu/pdfs/human/ biosimilar/043704en.pdf (last accessed 5 July 2010).
    • Guideline on Similar Biological Medicinal Products
  • 28
    • 77149122380 scopus 로고    scopus 로고
    • Biosimilars: Evidential standards for health technology assessment
    • Hughes DA. Biosimilars: evidential standards for health technology assessment. Clin Pharmacol Ther 2010 87 : 257 261.
    • (2010) Clin Pharmacol Ther , vol.87 , pp. 257-261
    • Hughes, D.A.1
  • 31
    • 76049096858 scopus 로고    scopus 로고
    • Does higher usage of low-cost statins correlate with a poorer achievement in cholesterol quality markers for secondary prevention?
    • Hickman J. Does higher usage of low-cost statins correlate with a poorer achievement in cholesterol quality markers for secondary prevention? Br J Gen Pract 2010 60 : 50 2.
    • (2010) Br J Gen Pract , vol.60 , pp. 50-2
    • Hickman, J.1
  • 32
    • 38849113845 scopus 로고    scopus 로고
    • Evaluation of the clinical outcomes of switching patients from atorvastatin to simvastatin and losartan to candesartan in a primary care setting: 2 years on
    • Usher-Smith J, Ramsbottom T, Pearmain H, Kirby M. Evaluation of the clinical outcomes of switching patients from atorvastatin to simvastatin and losartan to candesartan in a primary care setting: 2 years on. Int J Clin Pract 2008 62 : 480 484.
    • (2008) Int J Clin Pract , vol.62 , pp. 480-484
    • Usher-Smith, J.1    Ramsbottom, T.2    Pearmain, H.3    Kirby, M.4
  • 33
    • 70450221024 scopus 로고    scopus 로고
    • Much cheaper, almost as good: Decrementally cost-effective medical innovation
    • Nelson AL, Cohen JT, Greenberg D, Kent DM. Much cheaper, almost as good: decrementally cost-effective medical innovation. Ann Intern Med 2009 151 : 662 667.
    • (2009) Ann Intern Med , vol.151 , pp. 662-667
    • Nelson, A.L.1    Cohen, J.T.2    Greenberg, D.3    Kent, D.M.4
  • 34
    • 36148982628 scopus 로고    scopus 로고
    • Which statin, what dose?
    • Anon. Drug and Therapeutics Bulletin
    • Anon. Drug and Therapeutics Bulletin. Which statin, what dose? Drug Ther Bull 2007 45 : 33 6.
    • (2007) Drug Ther Bull , vol.45 , pp. 33-36
  • 35
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvasatatin in 20,536 high risk individuals: A randomised placebo-controlled trial
    • Heart Protection Study Collaborative Group
    • Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol lowering with simvasatatin in 20,536 high risk individuals: a randomised placebo-controlled trial. Lancet 2002 360 : 7 22.
    • (2002) Lancet , vol.360 , pp. 7-22
  • 36
    • 77955754609 scopus 로고    scopus 로고
    • National Institute for Health and Clinical Excellence. May 2008. Available at. (last accessed 5 July 2010)
    • National Institute for Health and Clinical Excellence. Clinical Guideline Number 67. May 2008. Available at http://www.nice.org.uk/CG067 (last accessed 5 July 2010).
    • Clinical Guideline Number 67
  • 37
    • 0037490080 scopus 로고    scopus 로고
    • Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: Systematic review and meta-analysis
    • Law MR, Wald NJ, Rudnicka AR. Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis. BMJ 2003 326 : 1423.
    • (2003) BMJ , vol.326 , pp. 1423
    • Law, M.R.1    Wald, N.J.2    Rudnicka, A.R.3
  • 38
    • 77951632946 scopus 로고    scopus 로고
    • WeMeReC Online resources. Available at. (last accessed 5 July 2010)
    • Duerden MG. Making sense of drug pricing. WeMeReC Online resources. 2006. Available at http://www.wemerec.org/Documents/enotes/MedicinesPricing.pdf (last accessed 5 July 2010).
    • (2006) Making Sense of Drug Pricing
    • Duerden, M.G.1
  • 39
    • 77950276201 scopus 로고    scopus 로고
    • New drugs for old: Disinvestment and NICE
    • Hughes DA, Ferner RE. New drugs for old: disinvestment and NICE. BMJ 2010 340 : c572.
    • (2010) BMJ , vol.340 , pp. 572
    • Hughes, D.A.1    Ferner, R.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.