Potential implications of genomic medicine in general practice

Medical Journal of Australia

Volumn 193, Issue 2, 2010, Pages 120-123

  Sullivan, Frank M ^a   Lockhart, Pauline M ^a   Usherwood, Timothy P ^b  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CONSULTATION; GENERAL PRACTICE; GENERAL PRACTITIONER; GENETIC SCREENING; GENOMICS; HUMAN; MEDICAL RESEARCH; MOLECULAR GENETICS; PATIENT CARE; PROGNOSIS; REVIEW;

EID: 77955737267     PISSN: 0025729X     EISSN: 13265377     Source Type: Journal    
DOI: 10.5694/j.1326-5377.2010.tb03820.x     Document Type: Review

References (27)

1. Feero WG, Guttmacher AE, Collins FS. Genomic medicine - an updated primer. N Engl J Med 2010; 362: 2001-2011.
2. National Center for Biotechnology Information. GenBank Statistics. http://www.ncbi.nlm.nih.gov/genbank/genbankstats.html (accessed May 2010).
3. Wolf CR, Smith G, Smith RL. Pharmacogenetics. BMJ 2000; 320: 987-990.
4. Starfield B, Holtzman NA, Roland MO, et al. Primary care and genetic services. Health care in evolution. Eur J Public Health 2002; 12: 51-56. (Pubitemid 34269961)
5. Bell J. The new genetics in clinical practice. BMJ 1998; 316: 618-620.
6. Biotechnology Australia. Genetics in family medicine: the Australian handbook for general practitioners. Canberra: Commonwealth of Australia, 2007. http://www.nhmrc.gov.au/your-health/egenetics/practitioners/gems.htm (accessed May 2010).
7. Andermann A, Blancquaert I, Beauchamp S, Dery V. Revisiting Wilson and Jungner in the genomic age: a review of screening criteria over the past 40 years. Bull World Health Organ 2008; 86: 317-319. (Pubitemid 351521860)
8. Allen KJ, Gurrin LC, Constantine CC, et al. Iron-overload-related disease in HFE hereditary hemochromatosis. N Engl J Med 2008; 358: 221-230.
9. Qaseem A, Aronson M, Fitterman N, et al. Screening for hereditary hemochromatosis: a clinical practice guideline from the American College of Physicians. Ann Intern Med 2005; 143: 517-521. (Pubitemid 41377200)
10. National Breast and Ovarian Cancer Centre. Familial risk assessment: breast and ovarian cancer (FRA-BOC). http://nbocc.org.au/fraboc/(accessed May 2010).
11. National Center for Biotechnology Information. OMIM - Online Mendelian Inheritance in Man. http://www.ncbi.nlm.nih.gov/omim (accessed May 2010).
12. Otlowski MFA, Williamson R. Ethical and legal issues and the "new genetics". Med J Aust 2003; 178: 582-585.
13. Hadithi M, von Blomberg ME, Crusius BA, et al. Accuracy of serologic tests and HLA-DQ typing for diagnosing celiac disease. Ann Intern Med 2007; 147: 294-302. (Pubitemid 351664556)
14. Coulter I. Genomic medicine: the sorcerer's new broom? West J Med 2001; 175: 424-426. (Pubitemid 33151091)
15. Choi M, Scholl UI, Ji W, et al. Genetic diagnosis by whole exome capture and massively parallel DNA sequencing. Proc Natl Acad Sci U S A 2009; 106: 19096-19101.
16. Palmer CNA, Ismail T, Lee SP, et al. Filaggrin null mutations are associated with increased asthma severity in children and young adults. J Allergy Clin Immunol 2007; 120: 64-68. doi: 10.1016/j.jaci.2007.04.001.
17. Dent T. Predicting the risk of coronary heart disease with conventional, genetic and novel molecular biomarkers. Cambridge, UK: PHG Foundation, 2010. http://www.phgfoundation.org/ (accessed May 2010).
18. Ashley EA, Butte AJ, Wheeler MT, et al. Clinical assessment incorporating a personal genome. Lancet 2010; 375: 1525-1535.
19. Treweek S, Pearson E, Smith N, et al. Desktop software to identify patients eligible for recruitment into a clinical trial: using SARMA to recruit to the ROAD feasibility trial. Inform Prim Care 2010; 18: 51-58.
20. Serretti A, Kato M, De Ronchi D, Kinoshita T. Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with selective serotonin reuptake inhibitor efficacy in depressed patients. Mol Psychiatry 2007; 12: 247-257. doi: 10.1038/sj.mp.4001926.
21. Evaluation of Genomic Applications in Practice and Prevention Working Group. Recommendations from the EGAPP Working Group: testing for cytochrome P450 polymorphisms in adults with nonpsychotic depression treated with selective serotonin reuptake inhibitors. Genet Med 2007; 9: 819-825.
22. Emery J, Morris H, Goodchild R, et al. The GRAIDS trial: a cluster randomised controlled trial of computer decision support for the management of familial cancer risk in primary care. Br J Cancer 2007; 97: 486-493. (Pubitemid 47258453)
23. Attia J, Ioannidis JP, Thakkinstian A, et al. How to use an article about genetic association. C: What are the results and will they help me in caring for my patients? JAMA 2009; 301: 304-308.
24. Burton H, Adams M, Bunton R, Schroeder-Baeck P. Developing stakeholder involvement for introducing public health genomics into public policy. Public Health Genomics 2009; 12: 11-19. Epub 2008; 3 Sep.
25. Smith BH, Campbell H, Blackwood D, et al. Generation Scotland: the Scottish Family Health Study; a new resource for researching genes and heritability. BMC Medical Genetics 2006; 7: 74.
26. McBride CM, Bowen D, Brody LC, et al. Future health applications of genomics: priorities for communication, behavioral, and social sciences research. Am J Prev Med 2010; 38: 556-565.
27. Smith BH, Watt GC, Campbell H, Sheikh A. Genetic epidemiology and primary care. Br J Gen Pract 2006; 56: 214-221.