Topical application of TRPM8 agonists accelerates skin permeability barrier recovery and reduces epidermal proliferation induced by barrier insult: role of cold-sensitive TRP receptors in epidermal permeability barrier homoeostasis

Experimental Dermatology

Volumn 19, Issue 9, 2010, Pages 791-795

  Denda, Mitsuhiro ^a   Tsutsumi, Moe ^a   Denda, Sumiko ^a  

^a SHISEIDO RESEARCH CENTER   (Japan)

Author keywords

Epidermis; Keratinocyte; Stratum corneum; Transient receptor potential; TRP

Indexed keywords

AMIDE; DERMATOLOGICAL AGENT; MENTHOL; N (4 BUTYLPHENYL) 4 (3 CHLOROPYRIDIN 2 YL)TETRAHYDROPYRAZINE 1 (2H) CARBOXAMIDE; N (4 METHOXYPHENYL) 5 METHYL 2 (1 METHYLETHYL)CYCLOHEXANECARBOXAMIDE; RUTHENIUM RED; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8; UNCLASSIFIED DRUG; WS 12;

ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; COLD SENSITIVITY; CONTROLLED STUDY; DRUG EFFECT; EPIDERMIS; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; MALE; MEMBRANE DAMAGE; MOUSE; NONHUMAN; PERMEABILITY BARRIER; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN PERMEABILITY;

ADMINISTRATION, CUTANEOUS; ANILIDES; ANIMALS; CELLS, CULTURED; EPIDERMIS; HOMEOSTASIS; HUMANS; HYPERPLASIA; KERATINOCYTES; MALE; MENTHOL; MICE; MICE, HAIRLESS; PERMEABILITY; PYRAZINES; PYRIDINES; RUTHENIUM RED; SKIN DISEASES; TRPM CATION CHANNELS;

EID: 77955730452     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.1600-0625.2010.01154.x     Document Type: Article

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