High frequency of MCM6 lactose intolerance genotype in Polynesian people

Alimentary Pharmacology and Therapeutics

Volumn 32, Issue 6, 2010, Pages 828-829

  Roberts, R L ^a,b   Merriman, T R ^a   Upton, J D ^c  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b UNIVERSITY OF OTAGO   (New Zealand)

^c CANTERBURY HEALTH LABORATORIES   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

LACTOSE; MINICHROMOSOME MAINTENANCE PROTEIN 6;

ABDOMINAL PAIN; ABORIGINE; ASIAN; BLOATING; CAUCASIAN; DAIRY PRODUCT; DIARRHEA; DIET; FLATULENCE; GENE EXPRESSION; GENOTYPE; HUMAN; LACTOSE INTOLERANCE; LETTER; NEW ZEALAND; POLYNESIA; PRIORITY JOURNAL; RACE DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; TAIWAN;

CELL CYCLE PROTEINS; DAIRY PRODUCTS; GENETIC VARIATION; GENOTYPE; HUMANS; LACTOSE INTOLERANCE; OCEANIC ANCESTRY GROUP;

EID: 77955730064     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/j.1365-2036.2010.04398.x     Document Type: Letter

References (6)

1. Lomer MC, Parkes GC, Sanderson JD. Review article: lactose intolerance in clinical practice - myths and realities. Aliment Pharmacol Ther 2008 27 : 93 103.
2. Enattah NS, Sahi T, Savilahti E, Terwilliger JD, Peltonen L, Jarvela I. Identification of a variant associated with adult-type hypolactasia. Nat Genet 2002 30 : 233 237.
3. Lewinsky RH, Jensen TG, Moller J, Stensballe A, Olsen J, Troelsen JT. T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro. Hum Mol Genet 2005 14 : 3945 3953.
4. Friedlaender JS, Friedlaender FR, Reed FA, et al. The genetic structure of Pacific Islanders. PLoS Genet 2008 4 : e19.
5. Upton J, George P. The prevalence of lactose intolerance (adult hypolactasia) in a randomly selected New Zealand population. N Z Med J 2010 123 : 123.
6. Horwath C, Parnell WR, Wilson NC, Russell DG. Attaining optimal bone status: lessons from the 1997 National Nutrition Survey. N Z Med J 2001 114 : 138 141.