The contribution of the cerebellum to cognition in Spinocerebellar Ataxia Type 6

Behavioural Neurology

Volumn 23, Issue 1-2, 2010, Pages 3-15

  Cooper, Freya E ^a   Grube, Manon ^a   Elsegood, Kelly J ^b   Welch, John L ^c   Kelly, Thomas P ^c   Chinnery, Patrick F ^c   Griffiths, Timothy D ^a,c  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b Trafford Child and Adolescent Mental Health Service   (United Kingdom)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

cerebellum; cognition; executive functions; neurodegeneration; SCA 6

Indexed keywords

ADULT; AGED; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CEREBELLAR ATAXIA; CEREBELLUM; CEREBELLUM DEGENERATION; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; FEMALE; HUMAN; INTELLIGENCE; MALE; MEMORY; NONVERBAL COMMUNICATION; PRIORITY JOURNAL; PSYCHOLOGIC ASSESSMENT; SPINOCEREBELLAR ATAXIA TYPE 6; SPINOCEREBELLAR DEGENERATION; VERBAL BEHAVIOR;

AGED; CEREBELLUM; COGNITION; COHORT STUDIES; DATA INTERPRETATION, STATISTICAL; EXECUTIVE FUNCTION; FEMALE; HUMANS; INTELLIGENCE TESTS; MAGNETIC RESONANCE IMAGING; MALE; MEMORY, SHORT-TERM; MENTAL PROCESSES; MIDDLE AGED; MOTOR SKILLS DISORDERS; NEUROPSYCHOLOGICAL TESTS; SPACE PERCEPTION; SPINOCEREBELLAR ATAXIAS; VERBAL BEHAVIOR;

EID: 77955728923     PISSN: 09534180     EISSN: None     Source Type: Journal    
DOI: 10.1155/2010/724861     Document Type: Article

References (68)

1. H. Ackermann, Cerebellar contributions to speech and language processing: Clinical and functional imaging data, Brain and Cognition 53 (2003), 102-103.
2. M. Bares, O. Lungu, T. Lui, T. Wachter, C. Gomez and J. Ashe, Cerebellum contributes to motor timing and prediction: Behavioural and fMRI study in healthy subjects and patients with spinocerebellar ataxia, Journal of Neurological Sciences Supplement 1 (2005), 236.
3. A.A.M. Bielak, L. Mansueti, E. Strauss and R.A. Dixon, Performance on the Haling and Brixton tests in older adults: Norms and correlates, Archives of Clinical Neuropsychology 21 (2006), 142-149.
4. J.R. Bloedel and V. Bracha, Duality of cerebellar and motor cognitive functions, The Cerebellum and Cognition: International Review of Neurobiology, J.D. Schmahmann, 1997.
5. J.W. Bohland and F.H. Guenther, An fMRI investigation of syllable sequence production, NeuroImage 32 (2006), 821-841.
6. M.I. Botez, J. Leveille, R. Lambert and T. Botez, Single photonemission computed tomography (SPECT) in cerebellar disease: Cerebellocereberal diaschisis, European Neurology 31 (1991), 405-412.
7. P.W. Burgess and T. Shallice, The Hayling and Brixton TestsManual, Thames Valley Test Company/Harcourt Assessment, London, 1997.
8. D. Butteriss, P.Chinnery andD. Birchall, Radiological characterization of spinocerebellar ataxia type 6, The British Journal of Radiology 78 (2005), 694-696.
9. S.H.A. Chen and J.E. Desmond, Temporal dynamics of cerebrocerebellar network recuitment during a cognitive task, Neuropsychologia 43 (2005), 1227-1237.
10. K.T. Ciesielski, P. Lesnik, R. Savoy, E.P. Grant and S.P. Ahlfors, Developmental neural networks in children performing a categorical Nback task, NeuroImage 33 (2006), 980-990.
11. J.W. Cohen, Statistical power analysis for the behavioural sciences, Lawrence Erlbaum Associates, Hillsdale, 1988.
12. F. Collette, M. Van der Linden, S. Laureys, F. Arigoni, G. Delfiore, C. Deguldre, A. Luxen and E. Salmon, Mapping the updating process: Common and specific brain activations across different versions of the running spatial span task, Cortex 43 (2007), 146-158.
13. S. de Ribaupierre, C. Ryser, J.G. Villemure and S. Clarke, Cerebellar lesions: Is there a lateralisation effect on memory deficits? Acta Neurochirurgica 150 (2008), 545-550.
14. D.C. Delis, E. Kaplan and J.H. Kramer, DelisKaplan Executive Function System (DKEFS) technical manual, The Psychological Corporation, San Antonio, 2001.
15. R. Dum, C. Li and P.L. Strick, Motor and non motor domains in the monkey dentate, Annals of The New York Academy of Sciences 978 (2002), 289-301.
16. F. Fabbro, A. Tavano, S. Corti, N. Bresolin, P. De Fabritiis and R. Borgatti, Long term neuropsychological deficits after cerebellar infarctions in two young adult twins, Neuropsychologia 42, (2004), 536-545.
17. B. Frank, B. Schoch, C. HeinKropp, A. Dimitrova, M. Hovel, W. Ziegler, E.R. Gizewski and D. Timmann, Verb generation in children and adults with acute cerebellar lesions, Neuropsychologia 45 (2007), 977-988.
18. P. Garrard, N.H. Martin, P. Giunti and L. Cipolotti, Cognitive and social cognitive functioning in spinocerebellar ataxia: A preliminary characterization, Journal of Neurology 255 (2008), 398-405.
19. C.F. Geier, K.E. Garver and B. Luna, Circuitry underlying temporally extended spatial working memory, NeuroImage 35 (2007), 904-915.
20. C. Globas, S. Bosch, C. Zuhlke, I. Daum, J. Dichgans and K. Burke, The cerebellum and cognition: Intellectual functioning in spinocerebellar ataxia type 6 (SCA6), Journal of Neurology 250 (2003), 1482-1487.
21. C.M. Gomez, R.M. Thompson, J.T. Gammack, S.L. Perlman, W.B. Dobyns, C.L. Truwit, D.S. Zee, H.B. Clarke and J.H. Anderson, Spinocerebellar ataxia tpe 6: Gaze evoked and vertigal nystagmus, Purkinje cell degeneration and variable age of onset, Annals of Neurology 42 (1997), 933-950.
22. B. Gottwald, Z. Mihajlovic, B. Wilde and H.M. Mehdorm, Does the cerebellumcontribute to specific aspects of attention? Neuropsychologia 41 (2003), 1452-1460.
23. B. Gottwald, B. Wilde, Z. Mihajlovic and H.M. Mehdorm, Evidence for distinct cognitive deficits after focal cerebellar lesions, Journal of Neurology, Neurosurgery and Psychiatry 75 (2004), 1524-1531.
24. E. Gowen and R.C. Miall, Behavioural aspects of cerebellar function in adults with Aspergers Syndrome, Cerebellum 4 (2005), 279-289.
25. A.E. Harding, The clinical features and classification of the late onset autosomal dominant cerebellar ataxias, Brain 105 (1982), 1-28.
26. G. Holmes, A form of familial degeneration of the cerebellum, Brain 30 (1908), 466-489.
27. M. Ito, Control of mental activities by internal models in the cerebellum, Nature Reviews Neuroscience 9 (2008), 304-313.
28. H. Jiang, B. Tang, K. Xia, Y. Zhou, B. Xu, G. Zhao, H. Li, L. Shen, Q. Pan and F. Cai, Spinocerebellar ataxia type 6 in mainland China: Molecular and clinical features in four families, Journal of the Neurological Sciences 236 (2005), 25-29.
29. T. Justus, The cerebellum and English grammatical morphology: Evidence from production, comprehension and gramaticality judgements, Journal of Cognitive Neuroscience 16 (2004), 1115-1130.
30. L.A. Kalashnikova, Y.V. Zueva, O.V. Pugacheva and N.K. Korsakova, Cognitive impairments in cerebellar infarcts, Neuroscience and Behavioural Physiology 35 (2005), 773-779.
31. Y. Kaseda, H. Kawakami, Z. Matsuyama, R. Kumagai, M. Toji, O. Komure, M. Nishimura, Y. Izumi, F. Vdaka, M. Kameyama, N. T, N. Sunohara, Y. Kuroda and S. Nakamura, Spinocerebellar ataxia type 6 in relation to CAG repeat length, Acta Neurologica Scandinavica 99 (1999), 209-212.
32. Y. Kawai, M. Suenga, H. Watanabe, M. Ito, K. Kato, T. Kato, K. Ito, F. Tanaka and G. Sobue, Prefrontal hypoperfusion and cognitive dysfunction correlates in spinocerebellar ataxia type 6, Journal of the Neurological Sciences 271 (2008), 68-74.
33. R.M.Kelly and P.L. Strick, Cerebellar loops withmotor cortex and prefrontal cortex of a nonhuman primate, The Journal of Neuroscience 23 (2003), 8432-8444.
34. M.P. Kirschen, M.S. DavisRatner, M.W. Milner, S.H.A. Chen, P. SchraedleyDesmond, P.G. Fisher and J.E. Desmond, Verbal memory impairments in children after cerebellar tumour resection, Behavioural Neurology 20 (2008), 39-53.
35. S.J. Kish, M. ElAwar, D. Stuss, J. Nobrega, R. Currier, J.F. Aita, L. Schut, H.Y. Zoghibi and M. Freedman, Neuropsychological test performance in patients with dominantly inherited spinocerebellar ataxia: Relationship to ataxia severity, Neurology 44 (1994), 1738-1746.
36. M.G. Leggio, A.M. Tedesco, F.R. Chiricozzi, S. Clausi, A. Orsini and M. Molinari, Cognitive sequencing impairment in patients with focal or atrophic cerebellar damage, Brain 131 (2008), 1332-1343.
37. H.C. Leiner, A.L. Leiner and R.S. Dow, Does the cerebellum contribute to mental skills? Behavioural Neuroscience 100 (1986), 443-454.
38. C.H. Lie, K. Specht, J.C.Marshall and G.R. Fink, Using fMRI to decompose the neural processes underlying the Wisconsin Card Sorting Test, NeuroImage 30 (2006), 1038-1049.
39. A. Lilja, P. Hamalainen, E. Kaitaranta and R. Rinne, Cognitive impairment in spinocerebellar ataxia type 8, Journal of the Neurological Sciences 237 (2005), 31-38.
40. C. Lukas, L. Schols, B. Bellenberg, U. Rub, H. Przuntek, G. Schmid, O. Koster and B. Suchan, Dissociation of grey and white matter reduction in spinocerebellar ataxia type 3 and 6: A voxelbased morphometry study, Neuroscience Letters 408 (2006), 230-235.
41. B.Machner, A. Sprender, D. Kompf andW. Heide, Cerebellar infarction affects visual search., Neuroreport 13 (2005), 1507-1511.
42. M.C. Mantovan, A. Martinuzzi, F. Squarzanti, A. Bolla, I. Silvestri, G. Liessi, C. Macchi, G. Ruzza, P. Trevisan and C. Angelini, Exploring mental status in Friedeichs ataxia: A combined neuropsychological, behavioural and neuroimaging study, European Journal of Neurology 13 (2006), 827-835.
43. F.A. Middleton and P.L. Strick, Cerebellar projections to the prefrontal cortex of the primate, The Journal of Neuroscience 21 (2001), 700-712.
44. U. Nagaoka, Y. Suzuki, T. Kawanami, K. Kurita, Y. Shikama, K. Honda, K. Abe, T. Nakajima and T. Kato, Regional differences in genetic subgroup frequency in hereditary cerebellar ataxia, and a morphometrical study of brain MR images in SCA1, MJD and SCA6, Journal of the Neurological Sciences
45. L.M. Parsons, J.M. Bower, J.H. Gao, J. Xiong and P.T. Fox, Lateral cerebellar hemispheres actively support sensory aquisition and discrimination rather than motor control, Learning and Memory 4 (1997), 49-62.
46. R.J. Perry and J.R. Hodges, Attention and executive deficits in Alzheimers Disease, Brain 122 (1999), 383-404.
47. I.F. Pollack, P. Polinko, A.L. Albright, R. Towbin and C. Fitz, Mutismand psudobulbar symptoms after resection of posterior fossa tumours in children: Incidence and pathophysiology, Neurosurgery 37 (1995), 885-893.
48. S.M. Ravizza, C.A. McCormick, J.E. Schlerf, T. Justus, R.B. Ivry and J.A. Fiez, Cerebellar damage produces selective deficits in verbal working memory, Brain 129 (2006), 306.
49. D. Riva and C. Giorgi, The cerebellum contributes to higher functions during development: Evidence from a series of children surgically treated for posterior fossa tumours, Brain 123 (2000), 1051-1061.
50. J.D. Schmahmann, Dysmetria of thought: Clinical consequences of cerebellar dysfunction on cognition and affect, Trends in Cognitive Neuroscience 2 (1998), 362-371.
51. J.D. Schmahmann, The cerebrocerebellar system: Anatomic structures of the cerebellar contribution to cognition and emotion, International Review of Psychiatry 13 (2001), 247-260.
52. J.D. Schmahmann and J.C. Sherman, The cerebellar cognitive affective syndrome, Brain 121 (1998), 561-579.
53. L. Schols, G. Amoiridis, T. Buttner, H. Przuntek, J.T. Epplen and O. Riess, Autosomal dominant cerebellar ataxia: Phenotypic differences in genetically defined subtypes? Annals of Neurology 42 (1997), 924-932.
54. L. Schols, R. Kruger, G. Amoiridis, H. Przuntek, J.T. Epplen and O. Riess, Spinocerebellar ataxia type 6: Genotype and phenotype in German kindreds, Journal of Neurology, Neurosurgery and Psychiatry 64 (1998), 67-73.
55. T.A. Schweizer, M.P.Alexander, M. Cusimano andD.T. Stuss, Fast and effcient visuotemporal attention requires the cerebellum, Neuropsychologia 45 (2007), 3068-3074.
56. J. Siffert, T. Young Poussain, L.C. Goumnerova, R.M. Scott, B. LaValley, N.J. Tarbell and S.L. Pmeroy, Neurological dysfunction associated with postoperative cerebellar mutism, Journal of NeuroOncology 48 (2000), 75-81.
57. M.C. Silveri, A.M. Di Betta, V. Filippni, M.G. Leggio and M. Molinari, Verbal short term store rehursal system and the cerebellum: Evidence from a patients with a right cerebellar lesion, Brain 121 (1998), 2175-2181.
58. R.J. Sinke, E.F. Ippel, C.M. Diepstraten, F.A. Breemer, J.H.J. Wokke, B.J. Van Hilten, V.A.M. Knoers, H.K.P. Van Amstel and H.P.H. Kremer, Clinical and molecular correlations in spinocerebellar ataxia type 6, Archives ofNeurology 58 (2001), 1839-1844.
59. C.J. Stoodley and J.D. Schmahmann, Functional topography in the human cerebellum: A metaanalysis of neuroimaging studies, NeuroImage 44 (2009), 489-501.
60. M. Suenaga, Y. Kawai, H. Watanabe, N. Atsuta, M. Ito, F. Tanaka, M. Katsuno, H. Fukatsu, S. Naganawa and G. Sobue, Cognitive impairment in spinocerebellar atxia type 6, Journal of Neurology, Neurosurgery and Psychiatry 79 (2008).
61. H. Takahasi, K. Ishikawa, T. Tsutsumi, H. Fujugasaki, A. Kawata, R. Okiyama, T. Fujita, K. Yoshizawa, S. Yamaguchi, H. Tomiyasu, F. Yoshii, K. Mitani, N. Shimizu, M. Yamazaki, T. Miyamoto, T. Orimo, S. Shoji, K. Kitamura and H. Mizusawa, A clinical and genetic study in a large cohot of patients with spinocerebella ataxia type 6, Journal of Human Genetics 49 (2004).
62. A. Tavano, R. Grasso, C. Gagliardi, F. Triulzi, N. Bresolin and F. Fabbro, Disorders of cognitive and affective development in cerebellar malformations, Brain 130 (2007), 2646-2660.
63. K. Tsuchiya, T. Oda, M. Yoshida, H. Sasaji, C. Haga, H. Okino, I. Tominaga, K. Matsui, H. Akiyama and Y. Hashizume, Degeneration of the inferior olive in spinocerebellar ataxia may depend on disease duration: Report of two autopsy cases and statistical analysis of autopsy cases reported to date, Neuropathology 25 (2005), 125-135.
64. D.Wechsler, Wechsler Adult Intelligence Scale - 3rd UK Edition, The Psychological Corporation, 1999.
65. D. Wechsler, Wechsler Memory Scale3rd UK Edition, The Psychological Corporation, 1999.
66. D. Wechsler, Wechsler Test of Adult Reading UK, The Psychological Corporation, 2001.
67. O. Zhuchenko, J. Bailey, P. Bonnen, T.Ashizawa, D.W. Stockton, C. Amos, W.B. Dobyns, S.H. Subramony, H.Y. Zoghibi and C.C. Lee, Autosomal dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the a1A voltage dependent calcium channel, Nature Genetics 15 (1997), 62-69.
68. H.Y. Zoghibi, CAG repeats in SCA6: Anticipating new clues, Neurology 49 (1997), 1196-1199.