Aortic dissection associated with cogans's syndrome: Deleterious loss of vascular structural integrity is associated with GM-CSF overstimulation in macrophages and smooth muscle cells

Journal of Cardiothoracic Surgery

Volumn 5, Issue 1, 2010, Pages

  Weissen Plenz, Gabriele ^a,b   Sezer, Ömer ^a   Vahlhaus, Christian ^a   Robenek, Horst ^b   Hoffmeier, Andreas ^a   Tjan, Tonny D T ^a   Scheld, Hans H ^a   Sindermann, Jürgen R ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MATRIX METALLOPROTEINASE;

AORTA; AORTA ANEURYSM; ARTICLE; BLOOD VESSEL; CASE REPORT; COGAN SYNDROME; DISSECTING ANEURYSM; FEMALE; HUMAN; IMMUNOLOGY; MIDDLE AGED; PATHOPHYSIOLOGY; SMOOTH MUSCLE FIBER;

ANEURYSM, DISSECTING; AORTA; AORTIC ANEURYSM; BLOOD VESSELS; COGAN SYNDROME; FEMALE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; MATRIX METALLOPROTEINASES; MIDDLE AGED; MYOCYTES, SMOOTH MUSCLE;

EID: 77955724586     PISSN: None     EISSN: 17498090     Source Type: Journal    
DOI: 10.1186/1749-8090-5-66     Document Type: Article

References (6)

1. Gluth MB, Baratz KH, Matteson EL, Driscoll CL. Cogan syndrome: a retrospective review of 60 patients throughout a half century. Mayo Clin Proc 2006, 81:483-488. 10.4065/81.4.483, 16610568.
2. Gaubitz M, Lübben B, Seidel M, Schotte H, Gramley F, Domschke W. Cogan's syndrome: organ-specific autoimmune disease or systemic vasculitis? A report of two cases and review of the literature. Clin Exp Rheumatol 2001, 19(4):463-469.
3. Bisdas TE, Teebken OE, Wilhelmi M, Lotz J, Bredt M, Haverich A, Pichlmaier MA. Surgical treatment of a thoracoabdominal aneurysm in Cogan's syndrome. Ann Thorac Surg 2009, 88:1668-1670. 10.1016/j.athoracsur.2009.04.081, 19853133.
4. Low AH, Su JW, Sin KY, Fong KY, Thumboo J. Cogan's syndrome with recurrent carotid and aortic aneurysms: a potentially fatal disorder mimicking Marfan syndrome. Scand J Rheumatol 2007, 36:71-73. 10.1080/03009740600907923, 17454940.
5. Plenz G, Eschert H, Beissert S, Arps V, Sindermann JR, Robenek H, Völker W. Alterations in the vascular extracellular matrix of granulocyte macrophage colony-stimulating factor (GM-CSF) -deficient mice. FASEB J 2003, 17:1451-1457. 10.1096/fj.02-1035com, 12890699.
6. Weissen-Plenz G, Eschert H, Volker W, Sindermann JR, Beissert S, Robenek H, Scheld HH, Breithardt G. Granulocyte macrophage colony-stimulating factor deficiency affects vascular elastin production and integrity of elastic lamellae. J Vasc Res 2008, 45:103-110. 10.1159/000109819, 17934321.