Tautomerism in drug discovery

Journal of Computer-Aided Molecular Design

Volumn 24, Issue 6-7, 2010, Pages 475-484

  Katritzky, Alan R ^a   Dennis Hall, C ^a   El Gendy, Bahaa El Dien M ^a,b   Draghici, Bogdan ^a  

^a University of Florida ^*  (United States)

^b BENHA UNIVERSITY   (Egypt)

Author keywords

Biological processes; Drugs; Energetics; Heterocycles; Tautomerism

Indexed keywords

'CURRENT; BIOLOGICAL PROCESS; DRUG; DRUG DISCOVERY; ENERGETIC; HETEROCYCLES; KINETIC ASPECTS; TAUTOMERISM; THERMODYNAMIC ASPECTS; THERMODYNAMICS AND KINETICS;

SOLVENTS;

2 AMINOTHIAZOLE DERIVATIVE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ABACAVIR; ALPHAGAN P; ARIPIPRAZOLE; BRIMONIDINE; CANDESARTAN HEXETIL; CATAPRESS TTS; CLONIDINE; EFAVIRENZ; ERLOTINIB; ESOMEPRAZOLE; HETEROCYCLIC COMPOUND; HYDROCHLOROTHIAZIDE PLUS LOSARTAN; IMIQUIMOD; IRBESARTAN; LAMOTRIGINE; LENALIDOMIDE; LOPINAVIR PLUS RITONAVIR; LOSARTAN; METAXALONE; METFORMIN PLUS PIOGLITAZONE; OLMESARTAN; PANTOPRAZOLE; PRAMIPEXOLE; ROSIGLITAZONE; SOLVENT; TENOFOVIR; TETRAZOLE DERIVATIVE; THALIDOMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALSARTAN; ZOLMITRIPTAN; DRUG;

DRUG DEVELOPMENT; DRUG INTERACTION; DRUG STRUCTURE; ISOMERISM; PH; PHARMACOKINETICS; PRIORITY JOURNAL; REVIEW; TAUTOMERIC SHIFT; TEMPERATURE; THERMODYNAMICS; CHEMISTRY;

DRUG DISCOVERY; HETEROCYCLIC COMPOUNDS; HYDROGEN-ION CONCENTRATION; ISOMERISM; PHARMACEUTICAL PREPARATIONS; THERMODYNAMICS;

EID: 77955716928     PISSN: 0920654X     EISSN: 15734951     Source Type: Journal    
DOI: 10.1007/s10822-010-9359-z     Document Type: Review

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