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Volumn 49, Issue 8, 2010, Pages 830-840

Serotonin transporter gene moderates the development of emotional problems among children following bullying victimization

Author keywords

bullying; emotional problems; geneenvironment interaction; serotonin transporter; victimization

Indexed keywords

SEROTONIN TRANSPORTER;

EID: 77955705136     PISSN: 08908567     EISSN: 15275418     Source Type: Journal    
DOI: 10.1016/j.jaac.2010.01.024     Document Type: Article
Times cited : (94)

References (50)
  • 2
    • 3543079179 scopus 로고    scopus 로고
    • Cross-national consistency in the relationship between bullying behaviors and psychosocial adjustment
    • T.R. Nansel, W. Craig, M.D. Overpeck, G. Saluja, and W.J. Ruan Cross-national consistency in the relationship between bullying behaviors and psychosocial adjustment Arch Pediatr Adolesc Med 158 2004 730 736
    • (2004) Arch Pediatr Adolesc Med , vol.158 , pp. 730-736
    • Nansel, T.R.1    Craig, W.2    Overpeck, M.D.3    Saluja, G.4    Ruan, W.J.5
  • 3
    • 77952421521 scopus 로고    scopus 로고
    • Bullying victimization in youths and mental health problems: 'Much ado about nothing'?
    • L. Arseneault, L. Bowes, and S. Shakoor Bullying victimization in youths and mental health problems: 'much ado about nothing'? Psychol Med 40 2010 717 729
    • (2010) Psychol Med , vol.40 , pp. 717-729
    • Arseneault, L.1    Bowes, L.2    Shakoor, S.3
  • 4
    • 38649099407 scopus 로고    scopus 로고
    • Targeting the murine serotonin transporter: Insights into human neurobiology
    • D.L. Murphy, and K.P. Lesch Targeting the murine serotonin transporter: insights into human neurobiology Nat Rev Neurosci 9 2008 85 96
    • (2008) Nat Rev Neurosci , vol.9 , pp. 85-96
    • Murphy, D.L.1    Lesch, K.P.2
  • 5
    • 0344011656 scopus 로고    scopus 로고
    • The serotonin transporter gene-linked polymorphism and negative emotionality: Placing single gene effects in the context of genetic background and environment
    • A. Holmes, and A.R. Hariri The serotonin transporter gene-linked polymorphism and negative emotionality: placing single gene effects in the context of genetic background and environment Genes Brain Behav 2 2003 332 335
    • (2003) Genes Brain Behav , vol.2 , pp. 332-335
    • Holmes, A.1    Hariri, A.R.2
  • 6
    • 33645799676 scopus 로고    scopus 로고
    • Genetics of emotional regulation: The role of the serotonin transporter in neural function
    • A.R. Hariri, and A. Holmes Genetics of emotional regulation: the role of the serotonin transporter in neural function Trends Cogn Sci 10 2006 182 191
    • (2006) Trends Cogn Sci , vol.10 , pp. 182-191
    • Hariri, A.R.1    Holmes, A.2
  • 7
    • 0037135137 scopus 로고    scopus 로고
    • Serotonin transporter genetic variation and the response of the human amygdala
    • A.R. Hariri, V.S. Mattay, and A. Tessitore Serotonin transporter genetic variation and the response of the human amygdala Science 297 2002 400 403
    • (2002) Science , vol.297 , pp. 400-403
    • Hariri, A.R.1    Mattay, V.S.2    Tessitore, A.3
  • 8
    • 13244259560 scopus 로고    scopus 로고
    • A susceptibility gene for affective disorders and the response of the human amygdala
    • A.R. Hariri, E.M. Drabant, and K.E. Munoz A susceptibility gene for affective disorders and the response of the human amygdala Arch Gen Psychiatry 62 2005 146 152
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 146-152
    • Hariri, A.R.1    Drabant, E.M.2    Munoz, K.E.3
  • 9
    • 59349119884 scopus 로고    scopus 로고
    • Genetic gating of human fear learning and extinction: Possible implications for gene-environment interaction in anxiety disorder
    • T.B. Lonsdorf, A.I. Weike, P. Nikamo, M. Schalling, A.O. Hamm, and A. Ohman Genetic gating of human fear learning and extinction: possible implications for gene-environment interaction in anxiety disorder Psychol Sci 20 2009 198 206
    • (2009) Psychol Sci , vol.20 , pp. 198-206
    • Lonsdorf, T.B.1    Weike, A.I.2    Nikamo, P.3    Schalling, M.4    Hamm, A.O.5    Ohman, A.6
  • 10
    • 41449090413 scopus 로고    scopus 로고
    • HPA axis reactivity: A mechanism underlying the associations among 5-HTTLPR, stress, and depression
    • I.H. Gotlib, J. Joormann, K.L. Minor, and J. Hallmayer HPA axis reactivity: a mechanism underlying the associations among 5-HTTLPR, stress, and depression Biol Psychiatry 63 2008 847 851
    • (2008) Biol Psychiatry , vol.63 , pp. 847-851
    • Gotlib, I.H.1    Joormann, J.2    Minor, K.L.3    Hallmayer, J.4
  • 11
    • 66149177049 scopus 로고    scopus 로고
    • Looking on the bright side: Biased attention and the human serotonin transporter gene
    • E. Fox, A. Ridgewell, and C. Ashwin Looking on the bright side: biased attention and the human serotonin transporter gene Proc Biol Sci 276 2009 1747 1751
    • (2009) Proc Biol Sci , vol.276 , pp. 1747-1751
    • Fox, E.1    Ridgewell, A.2    Ashwin, C.3
  • 12
    • 0242539691 scopus 로고    scopus 로고
    • Consequences of bullying in schools
    • K. Rigby Consequences of bullying in schools Can J Psychiatry 48 2003 583 590
    • (2003) Can J Psychiatry , vol.48 , pp. 583-590
    • Rigby, K.1
  • 13
    • 62649160099 scopus 로고    scopus 로고
    • Serotonin transporter genotype modulates social reward and punishment in rhesus macaques
    • K.K. Watson, J.H. Ghodasra, and M.L. Platt Serotonin transporter genotype modulates social reward and punishment in rhesus macaques PLoS ONE 4 2009 e4156
    • (2009) PLoS ONE , vol.4 , pp. 4156
    • Watson, K.K.1    Ghodasra, J.H.2    Platt, M.L.3
  • 14
    • 33746833331 scopus 로고    scopus 로고
    • Bullying victimization uniquely contributes to adjustment problems in young children: A nationally representative cohort study
    • L. Arseneault, E. Walsh, K. Trzesniewski, R. Newcombe, A. Caspi, and T.E. Moffitt Bullying victimization uniquely contributes to adjustment problems in young children: a nationally representative cohort study Pediatrics 118 2006 130 138
    • (2006) Pediatrics , vol.118 , pp. 130-138
    • Arseneault, L.1    Walsh, E.2    Trzesniewski, K.3    Newcombe, R.4    Caspi, A.5    Moffitt, T.E.6
  • 15
    • 39049140336 scopus 로고    scopus 로고
    • Being bullied as an environmentally mediated contributing factor to children's internalizing problems: A study of twins discordant for victimization
    • L. Arseneault, B.J. Milne, and A. Taylor Being bullied as an environmentally mediated contributing factor to children's internalizing problems: a study of twins discordant for victimization Arch Pediatr Adolesc Med 162 2008 145 150
    • (2008) Arch Pediatr Adolesc Med , vol.162 , pp. 145-150
    • Arseneault, L.1    Milne, B.J.2    Taylor, A.3
  • 16
    • 0036807407 scopus 로고    scopus 로고
    • Twins early development study (TEDS): A multivariate, longitudinal genetic investigation of language, cognition and behavior problems in childhood
    • A. Trouton, F.M. Spinath, and R. Plomin Twins early development study (TEDS): a multivariate, longitudinal genetic investigation of language, cognition and behavior problems in childhood Twin Res 5 2002 444 448
    • (2002) Twin Res , vol.5 , pp. 444-448
    • Trouton, A.1    Spinath, F.M.2    Plomin, R.3
  • 20
    • 0037270487 scopus 로고    scopus 로고
    • DNA from buccal swabs recruited by mail: Evaluation of storage effects on long-term stability and suitability for multiplex polymerase chain reaction genotyping
    • B. Freeman, N. Smith, C. Curtis, L. Huckett, J. Mill, and I.W. Craig DNA from buccal swabs recruited by mail: evaluation of storage effects on long-term stability and suitability for multiplex polymerase chain reaction genotyping Behav Genet 33 2003 67 72
    • (2003) Behav Genet , vol.33 , pp. 67-72
    • Freeman, B.1    Smith, N.2    Curtis, C.3    Huckett, L.4    Mill, J.5    Craig, I.W.6
  • 21
    • 0031441095 scopus 로고    scopus 로고
    • Serotonin transporter protein (SLC6A4) allele and haplotype frequencies and linkage disequilibria in African- and European-American and Japanese populations and in alcohol-dependent subjects
    • J. Gelernter, H. Kranzler, and J.F. Cubells Serotonin transporter protein (SLC6A4) allele and haplotype frequencies and linkage disequilibria in African- and European-American and Japanese populations and in alcohol-dependent subjects Hum Genet 101 1997 243 246
    • (1997) Hum Genet , vol.101 , pp. 243-246
    • Gelernter, J.1    Kranzler, H.2    Cubells, J.F.3
  • 24
    • 34247531449 scopus 로고    scopus 로고
    • Gene-environment correlations: A review of the evidence and implications for prevention of mental illness
    • S.R. Jaffee, and T.S. Price Gene-environment correlations: a review of the evidence and implications for prevention of mental illness Mol Psychiatry 12 2007 432 442
    • (2007) Mol Psychiatry , vol.12 , pp. 432-442
    • Jaffee, S.R.1    Price, T.S.2
  • 25
    • 67650305593 scopus 로고    scopus 로고
    • School, neighborhood, and family factors are associated with children's bullying involvement: A nationally representative longitudinal study
    • L. Bowes, L. Arseneault, B. Maughan, A. Taylor, A. Caspi, and T.E. Moffitt School, neighborhood, and family factors are associated with children's bullying involvement: a nationally representative longitudinal study J Am Acad Child Adolesc Psychiatry 48 2009 545 553
    • (2009) J Am Acad Child Adolesc Psychiatry , vol.48 , pp. 545-553
    • Bowes, L.1    Arseneault, L.2    Maughan, B.3    Taylor, A.4    Caspi, A.5    Moffitt, T.E.6
  • 26
    • 0035447649 scopus 로고    scopus 로고
    • Does bullying cause emotional problems?: A prospective study of young teenagers
    • L. Bond, J.B. Carlin, L. Thomas, K. Rubin, and G. Patton Does bullying cause emotional problems? A prospective study of young teenagers BMJ 323 2001 480 484
    • (2001) BMJ , vol.323 , pp. 480-484
    • Bond, L.1    Carlin, J.B.2    Thomas, L.3    Rubin, K.4    Patton, G.5
  • 27
    • 73549107229 scopus 로고    scopus 로고
    • 5-HTTLPR moderates the effect of relational peer victimization on depressive symptoms in adolescent girls
    • C. Benjet, R.J. Thompson, and I.H. Gotlib 5-HTTLPR moderates the effect of relational peer victimization on depressive symptoms in adolescent girls J Child Psychol Psychiatry Allied Disc 51 2009 173 179
    • (2009) J Child Psychol Psychiatry Allied Disc , vol.51 , pp. 173-179
    • Benjet, C.1    Thompson, R.J.2    Gotlib, I.H.3
  • 28
    • 0037678563 scopus 로고    scopus 로고
    • Prior juvenile diagnoses in adults with mental disorder: Developmental follow-back of a prospective-longitudinal cohort
    • J. Kim-Cohen, A. Caspi, T.E. Moffitt, H. Harrington, B.J. Milne, and R. Poulton Prior juvenile diagnoses in adults with mental disorder: developmental follow-back of a prospective-longitudinal cohort Arch Gen Psychiatry 60 2003 709 717
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 709-717
    • Kim-Cohen, J.1    Caspi, A.2    Moffitt, T.E.3    Harrington, H.4    Milne, B.J.5    Poulton, R.6
  • 29
    • 0037624040 scopus 로고    scopus 로고
    • Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene
    • A. Caspi, K. Sugden, and T.E. Moffitt Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene Science 301 2003 386 389
    • (2003) Science , vol.301 , pp. 386-389
    • Caspi, A.1    Sugden, K.2    Moffitt, T.E.3
  • 30
    • 18244389951 scopus 로고    scopus 로고
    • The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: A replication
    • K.S. Kendler, J.W. Kuhm, J. Vittum, C.A. Prescott, and B. Riley The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: a replication Am J Psychiatry 62 2005 529 535
    • (2005) Am J Psychiatry , vol.62 , pp. 529-535
    • Kendler, K.S.1    Kuhm, J.W.2    Vittum, J.3    Prescott, C.A.4    Riley, B.5
  • 31
    • 49749089269 scopus 로고    scopus 로고
    • New evidence for the association of the serotonin transporter gene (SLC6A4) haplotypes, threatening life events, and depressive phenotype
    • J. Lazary, A. Lazary, and X. Gonda New evidence for the association of the serotonin transporter gene (SLC6A4) haplotypes, threatening life events, and depressive phenotype Biol Psychiatry 64 2008 498 504
    • (2008) Biol Psychiatry , vol.64 , pp. 498-504
    • Lazary, J.1    Lazary, A.2    Gonda, X.3
  • 32
    • 70349768290 scopus 로고    scopus 로고
    • Interaction between genetic polymorphisms and stressful life events in first episode depression
    • J. Drachmann Bukh, C. Bock, M. Vinberg, T. Werge, U. Gether, and L. Vedel Kessing Interaction between genetic polymorphisms and stressful life events in first episode depression J Affect Disord 119 2009 107 115
    • (2009) J Affect Disord , vol.119 , pp. 107-115
    • Drachmann Bukh, J.1    Bock, C.2    Vinberg, M.3    Werge, T.4    Gether, U.5    Vedel Kessing, L.6
  • 33
    • 70350647033 scopus 로고    scopus 로고
    • Interactive effect of stressful life events and the serotonin transporter 5-HTTLPR genotype on posttraumatic stress disorder diagnosis in 2 independent populations
    • P. Xie, H.R. Kranzler, and J. Poling Interactive effect of stressful life events and the serotonin transporter 5-HTTLPR genotype on posttraumatic stress disorder diagnosis in 2 independent populations Arch Gen Psychiatry 66 2009 1201 1209
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 1201-1209
    • Xie, P.1    Kranzler, H.R.2    Poling, J.3
  • 34
    • 37349021685 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphism (5-HTTLPR) and anxiety reactivity in daily life: A daily process approach to gene-environment interaction
    • K.C. Gunthert, T.S. Conner, S. Armeli, H. Tennen, J. Covault, and H.R. Kranzler Serotonin transporter gene polymorphism (5-HTTLPR) and anxiety reactivity in daily life: a daily process approach to gene-environment interaction Psychosom Med 69 2007 762 768
    • (2007) Psychosom Med , vol.69 , pp. 762-768
    • Gunthert, K.C.1    Conner, T.S.2    Armeli, S.3    Tennen, H.4    Covault, J.5    Kranzler, H.R.6
  • 35
    • 13444280555 scopus 로고    scopus 로고
    • The relationship between stressful life events, the serotonin transporter (5-HTTLPR) genotype and major depression
    • N.A. Gillespie, J.B. Whitfield, B. Williams, A.C. Heath, and N.G. Martin The relationship between stressful life events, the serotonin transporter (5-HTTLPR) genotype and major depression Psychol Med 35 2005 101 111
    • (2005) Psychol Med , vol.35 , pp. 101-111
    • Gillespie, N.A.1    Whitfield, J.B.2    Williams, B.3    Heath, A.C.4    Martin, N.G.5
  • 36
    • 67649206975 scopus 로고    scopus 로고
    • Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression
    • N. Risch, R. Herrell, and T. Lehner Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression JAMA 301 2009 2462 2471
    • (2009) JAMA , vol.301 , pp. 2462-2471
    • Risch, N.1    Herrell, R.2    Lehner, T.3
  • 37
    • 73149123164 scopus 로고    scopus 로고
    • Gene-environment interactions: Biologically valid pathway or artifact?
    • M. Rutter, A. Thapar, and A. Pickles Gene-environment interactions: biologically valid pathway or artifact? Arch Gen Psychiatry 66 2009 1287 1289
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 1287-1289
    • Rutter, M.1    Thapar, A.2    Pickles, A.3
  • 38
    • 55449132547 scopus 로고    scopus 로고
    • Gene-environment interactions in depression research: Genetic polymorphisms and life-stress polyprocedures
    • S.M. Monroe, and M.W. Reid Gene-environment interactions in depression research: genetic polymorphisms and life-stress polyprocedures Psychol Sci 19 2008 947 956
    • (2008) Psychol Sci , vol.19 , pp. 947-956
    • Monroe, S.M.1    Reid, M.W.2
  • 39
    • 10344238087 scopus 로고    scopus 로고
    • Social supports and serotonin transporter gene moderate depression in maltreated children
    • J. Kaufman, B.Z. Yang, and H. Douglas-Palumberi Social supports and serotonin transporter gene moderate depression in maltreated children Proc Natl Acad Sci 101 2004 17316 17321
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 17316-17321
    • Kaufman, J.1    Yang, B.Z.2    Douglas-Palumberi, H.3
  • 40
    • 34250852332 scopus 로고    scopus 로고
    • No interaction between the serotonin transporter polymorphism (5-HTTLPR) and childhood adversity or recent stressful life events on symptoms of depression: Results from two community surveys
    • P. Chipman, A.F. Jorm, and M. Prior No interaction between the serotonin transporter polymorphism (5-HTTLPR) and childhood adversity or recent stressful life events on symptoms of depression: results from two community surveys Am J Med Genet Part B Neuropsychiatr Genet 144B 2007 561 565
    • (2007) Am J Med Genet Part B Neuropsychiatr Genet , vol.144 , pp. 561-565
    • Chipman, P.1    Jorm, A.F.2    Prior, M.3
  • 41
    • 33745684557 scopus 로고    scopus 로고
    • Gene-environment interactions in psychiatry: Joining forces with neuroscience
    • A. Caspi, and T.E. Moffitt Gene-environment interactions in psychiatry: joining forces with neuroscience Nature Rev Neurosci 7 2006 583 590
    • (2006) Nature Rev Neurosci , vol.7 , pp. 583-590
    • Caspi, A.1    Moffitt, T.E.2
  • 43
    • 28044472244 scopus 로고    scopus 로고
    • Genetic and environmental influences on anxious/depression during childhood: A study from the Netherlands Twin Register
    • D.I. Boomsma, C.E. van Beijsterveldt, and J.J. Hudziak Genetic and environmental influences on anxious/depression during childhood: a study from the Netherlands Twin Register Genes Brain Behav 4 2005 466 481
    • (2005) Genes Brain Behav , vol.4 , pp. 466-481
    • Boomsma, D.I.1    Van Beijsterveldt, C.E.2    Hudziak, J.J.3
  • 44
    • 52549105050 scopus 로고    scopus 로고
    • Genetic and environmental influences on the stability of withdrawn behavior in children: A longitudinal, multi-informant twin study
    • R.A. Hoekstra, M. Bartels, J.J. Hudziak, T.C. Van Beijsterveldt, and D.I. Boomsma Genetic and environmental influences on the stability of withdrawn behavior in children: a longitudinal, multi-informant twin study Behav Genet 38 2008 447 461
    • (2008) Behav Genet , vol.38 , pp. 447-461
    • Hoekstra, R.A.1    Bartels, M.2    Hudziak, J.J.3    Van Beijsterveldt, T.C.4    Boomsma, D.I.5
  • 45
    • 33645337891 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children
    • J. Kaufman, B.Z. Yang, and H. Douglas-Palumberi Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children Biol Psychiatry 59 2006 673 680
    • (2006) Biol Psychiatry , vol.59 , pp. 673-680
    • Kaufman, J.1    Yang, B.Z.2    Douglas-Palumberi, H.3
  • 46
    • 34548021027 scopus 로고    scopus 로고
    • Interactions between life stressors and susceptibility genes (5-HTTLPR and BDNF) on depression in Korean elders
    • J.M. Kim, R. Stewart, and S.W. Kim Interactions between life stressors and susceptibility genes (5-HTTLPR and BDNF) on depression in Korean elders Biol Psychiatry 62 2007 423 428
    • (2007) Biol Psychiatry , vol.62 , pp. 423-428
    • Kim, J.M.1    Stewart, R.2    Kim, S.W.3
  • 47
    • 12144287589 scopus 로고    scopus 로고
    • Rearing condition and rh5-HTTLPR interact to influence limbic-hypothalamic-pituitary-adrenal axis response to stress in infant macaques
    • C.S. Barr, T.K. Newman, and C. Shannon Rearing condition and rh5-HTTLPR interact to influence limbic-hypothalamic-pituitary-adrenal axis response to stress in infant macaques Biol Psychiatry 55 2004 733 738
    • (2004) Biol Psychiatry , vol.55 , pp. 733-738
    • Barr, C.S.1    Newman, T.K.2    Shannon, C.3
  • 48
    • 41449111073 scopus 로고    scopus 로고
    • Identifying molecular substrates in a mouse model of the serotonin transporter x environment risk factor for anxiety and depression
    • V. Carola, G. Frazzetto, and T. Pascucci Identifying molecular substrates in a mouse model of the serotonin transporter x environment risk factor for anxiety and depression Biolog Psychiatry 63 2008 840 846
    • (2008) Biolog Psychiatry , vol.63 , pp. 840-846
    • Carola, V.1    Frazzetto, G.2    Pascucci, T.3
  • 49
    • 53649104153 scopus 로고    scopus 로고
    • The serotonin transporter genotype is associated with intermediate brain phenotypes that depend on the context of eliciting stressor
    • N.H. Kalin, S.E. Shelton, A.S. Fox, J. Rogers, T.R. Oakes, and R.J. Davidson The serotonin transporter genotype is associated with intermediate brain phenotypes that depend on the context of eliciting stressor Mol Psychiatry 13 2008 1021 1027
    • (2008) Mol Psychiatry , vol.13 , pp. 1021-1027
    • Kalin, N.H.1    Shelton, S.E.2    Fox, A.S.3    Rogers, J.4    Oakes, T.R.5    Davidson, R.J.6
  • 50
    • 33846448741 scopus 로고    scopus 로고
    • Impaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice
    • C.L. Wellman, A. Izquierdo, and J.E. Garrett Impaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice J Neurosci 27 2007 684 691
    • (2007) J Neurosci , vol.27 , pp. 684-691
    • Wellman, C.L.1    Izquierdo, A.2    Garrett, J.E.3


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