Pharmacognostic and anti-hyperglycemic evaluation of Lantana camara (L.) var. aculeate leaves in alloxan-induced hyperglycemic rats

International Journal of Research in Pharmaceutical Sciences

Volumn 1, Issue 3, 2010, Pages 247-252

  Ganesh, T ^a   Sen, Saikat ^b   Thilagam, E ^a   Thamotharan, G ^a   Loganathan, T ^a   Chakraborty, Raja ^b  

^a JKK Munirajah Medical Research Foundation   (India)

^b CES College of Pharmacy   (India)

Author keywords

Antidiabetic activity; Lantana camara; Methanol extract; Pharmacognostic evaluation

Indexed keywords

ALLOXAN; ANTIDIABETIC AGENT; CHOLESTEROL; GLIBENCLAMIDE; GLUCOSE; HIGH DENSITY LIPOPROTEIN; LANTANA CAMARA EXTRACT; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETES MELLITUS; DOSE RESPONSE; DRUG EFFICACY; DRUG SCREENING; FLUORESCENCE ANALYSIS; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; HYPERLIPIDEMIA; LANTANA; LANTANA CAMARA; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PHARMACOGNOSY; PLANT LEAF; RAT; WEIGHT GAIN;

EID: 77955678584     PISSN: None     EISSN: 09757538     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Anonymous. Indian Medicinal Plants, A Compendium of 500 Species, Vol 3, Chennai:Orient Longman Pvt Ltd, 2006.
2. nd edition, New Delhi:Manager of Publications, 1966.
3. Anonymous. The wealth of India, Raw materials, Vol VI, New Delhi:Council of Scientific and Industrial Research, 1992.
4. Babu, V., Gangadevi, T. and Subramoniam, A. Antihy-perglycemic activity of Cassia Kleinii leaf extract in glucose fed normal rats and alloxan induced diabetic rats. Indian Journal of Pharmacology, vol 34, no. 6, November-December, 2002 pp. 409-415.
5. Brain, K.R. and Turner, T.D. The Practical Evaluation of Phytopharmaceuticals, Bristol:Wright-Scientechnica, 1975.
6. Dash, G.K., Suresh, P. and Ganapaty, S. Studies on hypoglycaemic and wound healing activities of Lantana camara Linn. Journal of Natural Remedies, vol 1, no, 2, 2001 pp. 105-110.
7. Davis, S.N. and Granner, D.K. 'Insulin, oral hypoglycaemic agents and the pharmacology of endocrine pancreas' in Hardman, J.G. and Limbird, L.E. (ed.) Goodman & Gillmans, The Pharmacological Basis of Therapeutics, New York, McGraw Hill, 2001.
8. De Mello, F.B., Jacubus, D., de Carvallo, K.C. and de Mello, J.R. Effects of Lantana camara (Verbenaceae) on rat fertility. Veterinary and Human Toxicology, vol 45, no. 1, 2003 pp. 20-23.
9. Dhawan, D., Bandhu, H.K., Singh, A. and Nagpal, J.P. Effect of D-400 (a herbal formulation) on the regulation of glucose metabolism in diabetic rats. Indian Journal of Pharmacology, vol 28, no. 4, October-December, 1996 pp. 224-226.
10. Fagbounka, B.S., Elias, S.O. and Adeneye, A.A. Evaluation of protective activity of ethanolic stem bark extract of Lantana camara on carbon tetrachloride-induced acute hepatic injury in Wister rats. Nigerian Journal of Health and Biomedical Science, vol 7, no. 2, 2008 pp. 9-13.
11. Garg, S.K., Shah, M.A. and Garg, K.M. Antilymphocytic and immunosuppressive effects of Lantana camara leaves in rats. Indian Journal of Experimental Biology, vol 35, no. 12, Decmber, 1997 pp. 1315-1318.
12. Ghisalberti, E.L. Lantana camara L. (Verbenaceae). Fitoterapia, vol 71, no. 5, September, 2000, pp. 467-485.
13. Hatapakki, B.C., Suresh, H.M., Bhoomannavar, V. and Shivakumar, S.I. Effect of Cassia auriculata Linn flowers against alloxan-induced diabetes in rats. Journal of Natural Remedies, vol 5, no. 2, June, 2005 pp. 132-136.
14. Jahan, N., Afaque, S.H., Khan, N.A., Ahmad, G. and Ansari, A.A. Physico-chemical studies of the gum acacia. Natural Product Radiance, vol 7, no, 4, July-August, 2008 pp. 335-337.
15. Jithendra, C.H., Muralidharan, P. Anti-hyperglycemic and antioxidant activities of the ayurvedic drug Nisha kathakathadhi churnam in alloxan-induced hyperglycemic rats. International Journal of Green Pharmacy, vol 3, no. 1, January-March, 2009 p. 66-69.
16. Kar, A. Pharmaceutical drug analysis. New Delhi:New Age International (P) Limited,.2005.
17. Kashyapa, K. and Chand, R. The Useful Plants of India. New Delhi: Council of Scientific and Industrial Research, 2006.
18. th edition, Pune:Nirali Prakashan, 2004.
19. Kokate, C.K. Practical Pharmacognosy, New Delhi:Vallabh Prakashan, 1985.
20. th edition, Pune:Nirali Prakashan, 2006.
21. Misra, L.N., Dixit, A.K. and Sharma, R.P. High concentration of hepatoprotective oleanolic acid and its derivatives in Lantana camara roots. Planta Medica, vol 63, no. 6, December, 1997 pp. 582.
22. Misra, N. and Sharma, K. Chemical constituents and antifilarial activity of Lantana camara against human lymphatic filarid brugia malayi and rodent filarid Acanthocheilonema viteae maintained in rodent rats. Parasitology Research, vol 100, no 3, February, 2007 pp. 439-448.
23. Mukherjee, P.K. Quality control of herbal drugs, New Delhi:Business Horizons, 2002.
24. Noble, D., Lane, S.J., Sidebottom, P.J. and Lynn, S.M. Isolation of translactone-containing triterpenes with thrombin inhibitory activities from the leaves of Lantana camara. Journal of Natural Product, vol 61, no. 11, November, 1998 pp. 1328-1331.
25. Raghu, C., Ashok, G. and Suresh, B. In vitro cytotoxic activity of Lantana camara Linn. Indian Journal of Pharmacology, vol 36, no. 2, March-April, 2004 pp. 94-95.
26. Rajesh, K., and Suman, K. Phytochemical and termiticidal study of Lantana camara var. aculeata leaves. Fitoterapia, vol 77, no. 3, Setember, 2006 pp. 466-468.
27. Sharma, O.P., Makkar, H.P. and Dawra, R.K. Toxicity of isolated lantana (L. camara L.) constituents to male and female guinea pigs. Veterinary and Human Toxicology, vol, 31, no. 1, February, 1989 pp. 10-13.
28. Sharma, O.P., Makkhar, H.P. and Dawra, R.K. A review of the noxious plant L. camara. Toxicon, vol 26, no. 11, 1988 pp. 975-987.
29. Sridevi, S., Chary, M.G., Krishna, D.R. and Diwan, P.V. Pharmacodynamic evaluation of transdermal drug delivery system of glibenclamide in rats. Indian Journal of Pharmacology, vol 32, no. 5, September-October, 2000 pp. 309-312.
30. Taylor, S.I. Deconstructing type 2 diabetes. Cell, vol 97, no. 1, April, 1999 pp. 9-12.
31. Tiwari, A.K. and Rao, J.M. Diabetes mellitus and multiple therapeutic approaches of phytochemicals: present status and future prospects. Current Sciences, vol 83, no. 1, July, 2002 pp. 30-38.
32. Xie, J.T., Wang, A., Mehendale, S., Wu, J., Aung, H.H., Dey, L., Qiu, S. and Yuan, C.S. Anti-diabetic effects of Gymnema yunnanense extract. Pharmacology Research, vol 47, no. 4, April, 2003 pp. 323-329.
33. Yarnalkar, S. Practical Pharmacognosy, Pune:Nirali Prakashan, 1991.